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Rickettsia conorii str. Malish 7 (rcon0)
Gene : dnaE
DDBJ      :dnaE         DNA polymerase III alpha chain
Swiss-Prot:DPO3A_RICCN  RecName: Full=DNA polymerase III subunit alpha;         EC=2.7.7.7;

Homologs  Archaea  0/68 : Bacteria  908/915 : Eukaryota  3/199 : Viruses  3/175   --->[See Alignment]
a.4.6a.60.2b.29.1b.40.4b.42.4c.6.3d.58.1
:1181 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   4->1033 3e0dA PDBj e-172 38.6 %
:RPS:PDB   5->1051 3e0dA PDBj 0.0 37.1 %
:RPS:SCOP  51->156 1q16B  d.58.1.5 * 4e-10 10.6 %
:RPS:SCOP  289->422 1r8nA  b.42.4.1 * 1e-30 16.0 %
:RPS:SCOP  399->490 1fc3A  a.4.6.3 * 7e-21 12.0 %
:RPS:SCOP  686->825 1kitA2  b.29.1.8 * 6e-29 13.4 %
:RPS:SCOP  875->927 2eduA1  a.60.2.7 * 2e-05 20.0 %
:RPS:SCOP  983->1097 1asyA1  b.40.4.1 * 9e-13 13.5 %
:HMM:SCOP  4->260 1m65A_ c.6.3.1 * 2.6e-13 20.3 %
:RPS:PFM   8->136 PF02811 * PHP 2e-08 38.3 %
:RPS:PFM   303->712 PF07733 * DNA_pol3_alpha e-126 56.9 %
:HMM:PFM   293->734 PF07733 * DNA_pol3_alpha 2.2e-161 53.4 412/422  
:HMM:PFM   6->177 PF02811 * PHP 4.9e-25 30.0 170/175  
:HMM:PFM   1025->1099 PF01336 * tRNA_anti 2.2e-06 18.1 72/76  
:BLT:SWISS 1->1181 DPO3A_RICCN 0.0 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAL03749.1 GT:GENE dnaE GT:PRODUCT DNA polymerase III alpha chain GT:DATABASE GIB00062CH01 GT:ORG rcon0 GB:ACCESSION GIB00062CH01 GB:LOCATION complement(1105664..1109209) GB:FROM 1105664 GB:TO 1109209 GB:DIRECTION - GB:GENE dnaE GB:PRODUCT DNA polymerase III alpha chain GB:PROTEIN_ID AAL03749.1 GB:DB_XREF GI:15620342 GB:GENE:GENE dnaE LENGTH 1181 SQ:AASEQ MRPEFIHLRTQSSYSFLESALTIEKVVELASSNKMPAICLADKGNLFGSLEFALCAVKKGLQPIHGVILNIKYDIDIFAQILLIAKDETGYKNLLKLSSLTFTKNDRKICDHIDFEDLIEYQEGLIGLCCYTDGIVGKCLLARNEEQAMLFARKLQEILGDRFYFEIMRHELPEEQFIEDSYIRIAAELAIPLVATNKVLFSEKSMHDAHDVLLCISAGVTKEYLDRKTVSENCYFKSPHEMIELFSDLPSAIQNTVNLRERCYFAAHANPPMLPNFATENISETDLIKKDAKEGLLARLATKFKSENIALENQEALKTEYFARLNYELDIICNMNFAGYFLIVSDFIKWSKKEGILVGPGRGSGAGSVVAWSLLITDLDPIKFGLLFERFLNPERISMPDFDIDFCQERREEVINYVRSKYGNNRVGQIITFGKMQAKAVIKDVARVLSLPYKFADYLTELVPFSAVNPVSLEQAMREVPELANAAKGNGLYNLDGEAELIKLVIDTSLILEGLHRHSSTHAAGIVIAGTDLVDIVPVYKDANSDMLIVGYSMKYSEIAGLIKFDFLGLQTLTVITDCKKLLKEQGIEVDFNNMTFDDNKTYQMLCKGKGVGVFQFESIGMKDALRRLKPDSIHDLIALGALYRPGPMENIPTYIACKHKLQQPDYLHELLQPILEETYGVVIYQEQVQRIAQVLAGYTLGAADLLRRAMGKKIKKEMEEQEEIFVKGAIANNISESQAKSIFATVAKFAGYGFNKAHAASYGVISYQTAYLKANYPAAFLVACLNLELNNHDKINLFLQEAKDNGIKIIAPNINISEGYFSVKFSDTVIPHSVKPVIPRLDRGIQKISKDTVVKPRCDIAGAIIFALGAIKGVTPNFGKLVTDERKARGAFKSITDFIERLPPKSINSKLLENLIKSGCFDELHDNRLQLLSSIPKLLSYSTAYHEEQESNQFSLIKVSSLSPTILVSSDYADKNTLAFYEFEAMGLFISNHPLTEYQEIFSRLNILNTADLHNNLPDGTNRVNLAGVIQKKDSRMSARGRFVTLVLSDPENIFELSIFSEEVLKDYVHLLDVKSLVVVNCDIVKDEGGIKLTAKSFSSIEDAINNKQFELQFYPQNHEELRQIVTLLAARINNEDQSNAKATIYLQSADVKNFVAKITLPEKFLLQGQDFEILKGYSK GT:EXON 1|1-1181:0| SW:ID DPO3A_RICCN SW:DE RecName: Full=DNA polymerase III subunit alpha; EC=2.7.7.7; SW:GN Name=dnaE; OrderedLocusNames=RC1211; SW:KW Complete proteome; Cytoplasm; DNA replication;DNA-directed DNA polymerase; Nucleotidyltransferase; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->1181|DPO3A_RICCN|0.0|100.0|1181/1181| GO:SWS:NREP 5 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006260|"GO:DNA replication"|DNA replication| GO:SWS GO:0003887|"GO:DNA-directed DNA polymerase activity"|DNA-directed DNA polymerase| GO:SWS GO:0016779|"GO:nucleotidyltransferase activity"|Nucleotidyltransferase| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| SEG 713->728|kkikkemeeqeeifvk| SEG 861->874|iagaiifalgaikg| BL:PDB:NREP 1 BL:PDB:REP 4->1033|3e0dA|e-172|38.6|977/1148| RP:PDB:NREP 1 RP:PDB:REP 5->1051|3e0dA|0.0|37.1|996/1148| RP:PFM:NREP 2 RP:PFM:REP 8->136|PF02811|2e-08|38.3|120/177|PHP| RP:PFM:REP 303->712|PF07733|e-126|56.9|399/428|DNA_pol3_alpha| HM:PFM:NREP 3 HM:PFM:REP 293->734|PF07733|2.2e-161|53.4|412/422|DNA_pol3_alpha| HM:PFM:REP 6->177|PF02811|4.9e-25|30.0|170/175|PHP| HM:PFM:REP 1025->1099|PF01336|2.2e-06|18.1|72/76|tRNA_anti| GO:PFM:NREP 4 GO:PFM GO:0003824|"GO:catalytic activity"|PF02811|IPR004013| GO:PFM GO:0005737|"GO:cytoplasm"|PF07733|IPR011708| GO:PFM GO:0006260|"GO:DNA replication"|PF07733|IPR011708| GO:PFM GO:0008408|"GO:3'-5' exonuclease activity"|PF07733|IPR011708| RP:SCP:NREP 6 RP:SCP:REP 51->156|1q16B|4e-10|10.6|104/509|d.58.1.5| RP:SCP:REP 289->422|1r8nA|1e-30|16.0|119/185|b.42.4.1| RP:SCP:REP 399->490|1fc3A|7e-21|12.0|92/119|a.4.6.3| RP:SCP:REP 686->825|1kitA2|6e-29|13.4|134/197|b.29.1.8| RP:SCP:REP 875->927|2eduA1|2e-05|20.0|50/91|a.60.2.7| RP:SCP:REP 983->1097|1asyA1|9e-13|13.5|111/137|b.40.4.1| HM:SCP:REP 4->260|1m65A_|2.6e-13|20.3|232/0|c.6.3.1|1/1|PHP domain-like| OP:NHOMO 1251 OP:NHOMOORG 914 OP:PATTERN -------------------------------------------------------------------- 3222222222222222222-22112222222222222222222232222211242221112222113232111112111111211111111111111112131224141311111111111111111111-111111111111112221122211221111111121222211111111111121111111211111111111111121111112111111111111111111111111111111111112111111111111111111211111111111111111111111111111111111111111111111111111111211211111111111111-2111112111111111111211111111212322211111222223222222222122221213122223222322-3442332333232322232221222221111111124221211111111111111111111111111111111222212221242532232222333223222224222221122223422222231222211111111111111222222131111111111121211112122222212111111111111111111111111122111222121112111111111112112111111122111111111111111111111111-11111111111111111111111111111111111111211111111111111112112222111111111111111121211111111111-11111111111111111222222222222222221111111111111111111222222222222222111111111111111111111111111111-11111111111111111111111111111121 -------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------1--------------3---------- --------------1-----------------------------------------------------------------1---------------------------------------------1------------------------------------------------ STR:NPRED 1026 STR:RPRED 86.9 SQ:SECSTR cEEEccccccccTTcTTTccccHHHHHHHHHHHcccEEEEEEETccTTHHHHHHHHHTTTcEEEEEEEEEEEcccTTEEEEEEEEccHHHHHHHHHHHHHHHHTccccccEEEcHHHHHHTcTTEEEEcccTTcHHHHHHHTTcHHHHHHHHHHHHHHHGGGEEEEEcccccHHHHHHHHHHHHHHHHTTccEEEccccccccGGGHHHHHHHHHHHTTcccccccccccccccccccHHHHHHHccHHHHHHHHHHHHHHTcccccccTTccccccccccccHHHHHHHHHHHHHHHHcTTTccHHHHTTTTccccHHHHHHHHHHHHHHHHHHTcHHHHHHHHHHHHHHHTTTcccccccGGGGGcHHHHHTTcccccTTTTTccHHHHccTTcccccccEEEEETTTHHHHHHHHHHHHcTTTEEEEEEEccccHHHHHHHHHHHTTccHHHHHHHHTTccccccccccTTTTTcccTTTTTHHHHc#HHHHcHHcHHHHHHHHHHHHcTTccccEEEcccEEEEccccGGGTccEEEcTTGccEEEEEEHHHHHTTTcEEEEEEEEHHHHHHHHHHHHHHHHcccccGGGccTTcHHHHHHHHTTccTTcTTcccHHHHHHHHHHccccHHHHHHHHHHccTTGGGHHHHHHHHHTTccccccTHHHHHHHHGGGTTccccHHHHHHHHHHHccccHHHHHHHHHHHHHTcTTTHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHTTccccHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHTTTcHHHHHHHHHHHHTTcccEEcccTTTcccccEEETTTEEEcccGGGc#####TccTTcccHHHH##################cccHHHHHHHHHHHHHccccccHHHHHHHccTTTccHHHHHHHHHHTTTGGGcccHHHHHHHHHHHHHHHHHHHHHHTTccccccccccccccccccccccHHHHHHHHHHHHHcccccccGGGTcHHHHccccGGGHHHHHcccc#cccEEEEEEEEccccEEEEETTEEEEEccTT################################################################################################################################## DISOP:02AL 1-2, 949-957| PSIPRED cccccEEEEcccccHHHHHcccHHHHHHHHHHccccEEEEEccccHHHHHHHHHHHHHccccEEEEEEEEEEEcccccccEEEEEEcHHHHHHHHHHHHHHHHHccccccccccHHHHHHHHccEEEEccccccHHHHHHHcccHHHHHHHHHHHHHHccccEEEEEEEcccHHHHHHHHHHHHHHHHHcccEEEEcccHHccHHHHHHHHHHHHHHcccccccHHHcccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHcEEEccccccccccccccccHHHHHHHHHHHHHHHHHHHcccHHHHHccccccccHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHcccEEccccccHHHHHHHHHHHcccccccccccccccccccccccccEEEcccccccHHHHHHHHHHHcccccEEEEEEEEEHHHHHHHHHHHHHHcccHHHHHHHHHHccccccccccHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHcccccccccccEEEEEcccccEEEEccEEccccccEEEEEcHHHHHHcccEEEEEEccccHHHHHHHHHHHHHccccccHHHcccccHHHHHHHHccccEEEEEcccHHHHHHHHHcccccHHHHHHHHHcccccccccccHHHHccccccccccccHHHHHHHHccccEEEcHHHHHHHHHHHccccHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHcccEEccHHHccccccccccccccHHHHHHHHHHHHHHcccHHHHHHHccccccccccEEEccHHHcccccHHHHHHHHHHHHcccccccHHHHHHHcccccccHHHHHHHHHccccccccHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccccccccccccccHHHHHHHHHHHHcEEEcccHHHHHHHHHHHcccccHHHHHHHHcccccEEEEEEEEEEEEEEEcccccEEEEEEEccccEEEEEEccHHHHHHHHHHHccccEEEEEEEEEEEccEEEEEEEEcccHHHHHHHHccEEEEEEcccHHHHHHHHHHHHHcccccccccEEEEEEEEccccEEEEEEEEcccEEEcHHHHHHHHcccc 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