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Rickettsia conorii str. Malish 7 (rcon0)
Gene : gyrA
DDBJ      :gyrA         DNA gyrase subunit A
Swiss-Prot:GYRA_RICCN   RecName: Full=DNA gyrase subunit A;         EC=5.99.1.3;

Homologs  Archaea  22/68 : Bacteria  910/915 : Eukaryota  187/199 : Viruses  8/175   --->[See Alignment]
b.68.10e.11.1
:905 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   31->485 1ab4A PDBj e-134 56.3 %
:BLT:PDB   527->883 1zi0B PDBj 6e-55 40.1 %
:RPS:PDB   31->512 1ab4A PDBj e-159 57.5 %
:RPS:PDB   518->633 3dwpC PDBj 1e-32 14.2 %
:RPS:PDB   640->734 3dwpC PDBj 2e-06 5.8 %
:RPS:PDB   784->879 3dwpA PDBj 8e-12 8.8 %
:RPS:SCOP  31->512 1ab4A  e.11.1.1 * e-160 57.5 %
:RPS:SCOP  525->882 1wp5A  b.68.10.1 * 1e-86 24.2 %
:HMM:SCOP  1->516 1bjtA_ e.11.1.1 * 1.2e-180 56.1 %
:HMM:SCOP  524->900 1wp5A_ b.68.10.1 * 6.7e-97 46.1 %
:RPS:PFM   33->485 PF00521 * DNA_topoisoIV e-156 66.5 %
:RPS:PFM   528->574 PF03989 * DNA_gyraseA_C 2e-04 36.2 %
:RPS:PFM   686->733 PF03989 * DNA_gyraseA_C 2e-04 41.7 %
:RPS:PFM   836->882 PF03989 * DNA_gyraseA_C 1e-04 38.3 %
:HMM:PFM   33->496 PF00521 * DNA_topoisoIV 4.6e-158 52.6 422/426  
:HMM:PFM   529->567 PF03989 * DNA_gyraseA_C 4.2e-09 25.6 39/50  
:HMM:PFM   582->624 PF03989 * DNA_gyraseA_C 0.00029 22.5 40/50  
:HMM:PFM   639->683 PF03989 * DNA_gyraseA_C 2.1e-08 24.4 45/50  
:HMM:PFM   686->734 PF03989 * DNA_gyraseA_C 3.3e-15 39.6 48/50  
:HMM:PFM   785->833 PF03989 * DNA_gyraseA_C 2.4e-10 22.9 48/50  
:HMM:PFM   835->882 PF03989 * DNA_gyraseA_C 3.9e-17 35.4 48/50  
:BLT:SWISS 1->883 GYRA_RICCN 0.0 100.0 %
:COIL
:REPEAT 2|640->733|787->882
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAL02811.1 GT:GENE gyrA GT:PRODUCT DNA gyrase subunit A GT:DATABASE GIB00062CH01 GT:ORG rcon0 GB:ACCESSION GIB00062CH01 GB:LOCATION 274436..277153 GB:FROM 274436 GB:TO 277153 GB:DIRECTION + GB:GENE gyrA GB:PRODUCT DNA gyrase subunit A GB:PROTEIN_ID AAL02811.1 GB:DB_XREF GI:15619329 GB:GENE:GENE gyrA LENGTH 905 SQ:AASEQ MTDKSSSNLVPVNIEDEMKVSYLDYAMSVIVSRAIPDVRDGLKPVHRRIIYSMHEAGNHASKPYRKSARIVGDVMGKYHPHGDSAIYDALVRMAQDFSLRLPLVDGQGNFGSMDGDAAAAMRYTESRMAKVSYKLVEDIDKETVSFNPNYDGSEEEPSVLPAMFPNLLVNGSGGIAVGMATNIPPHNLGEVIDACCLYIDNNDIEILDLLEVVKGPDFPTGSMILGISGIRSAYLTGRGSIIMRGRAEIENIGNNRQAIIITEIPYMVNKARLVEKIAEMVKEKRIEGISDLRDESNKNGVRIFIELKKDVVAEVVLNQIYACTQLQTSFGVIMLALKDGLPKVMNLKEVIAAFVSFREVVITNRTIYLLNKARDRAHILLGLTIAVSNIDEIIRIIKASNDSNAAKQELMARQWEALNILPLVKLVDDKAMLNEQGKCNFTEVQAKAILEMRLQRLTAMEKNKLEEDLKNLITEITEYLNILGSRTRLLEILKEELIKVKEEFATPRLTSIEFGEFDQDIEDLIQREEMVVTVTLGGYIKRVPLSSYRAQKRGGKGRSGLSMRDEDITTQVFVGSTHTPMLFFSNIGQVYSLKLYKLPLSNPQGKGRPMVNILPLKANEHITNIMPLPENQDERDNLNIMFATAKGNIRRSDLLDFKKLQSNGKIAIRLDEDDKLIDVKPCKEDEHILLATKAGKALRFPVESLRVIKSRTSDGVRGMKLAKEDSVISMTVLKGISSTKEDRDAYLSVPWEQRLEIAKGEAFNPEELGVSLTAPAIVEMANSEEFILTVTENGFGKRSSAYGYRITDRGGSGIINMDINDKTGLVVGVMPVKMDDELMLITNSGKLIRCKLESVRITGRNTSGVILFKLDDGEKVVSVSLIAETAESEEDSELEEEGLEQSEEV GT:EXON 1|1-905:0| SW:ID GYRA_RICCN SW:DE RecName: Full=DNA gyrase subunit A; EC=5.99.1.3; SW:GN Name=gyrA; OrderedLocusNames=RC0273; SW:KW ATP-binding; Complete proteome; DNA-binding; Isomerase;Nucleotide-binding; Topoisomerase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->883|GYRA_RICCN|0.0|100.0|883/905| GO:SWS:NREP 5 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding| GO:SWS GO:0016853|"GO:isomerase activity"|Isomerase| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0003916|"GO:DNA topoisomerase activity"|Topoisomerase| COIL:NAA 31 COIL:NSEG 1 COIL:REGION 467->497| NREPEAT 1 REPEAT 2|640->733|787->882| SEG 489->503|lleilkeelikvkee| SEG 884->904|etaeseedseleeegleqsee| BL:PDB:NREP 2 BL:PDB:REP 31->485|1ab4A|e-134|56.3|444/477| BL:PDB:REP 527->883|1zi0B|6e-55|40.1|294/296| RP:PDB:NREP 4 RP:PDB:REP 31->512|1ab4A|e-159|57.5|471/477| RP:PDB:REP 518->633|3dwpC|1e-32|14.2|113/120| RP:PDB:REP 640->734|3dwpC|2e-06|5.8|94/120| RP:PDB:REP 784->879|3dwpA|8e-12|8.8|95/116| RP:PFM:NREP 4 RP:PFM:REP 33->485|PF00521|e-156|66.5|424/434|DNA_topoisoIV| RP:PFM:REP 528->574|PF03989|2e-04|36.2|47/50|DNA_gyraseA_C| RP:PFM:REP 686->733|PF03989|2e-04|41.7|47/50|DNA_gyraseA_C| RP:PFM:REP 836->882|PF03989|1e-04|38.3|47/50|DNA_gyraseA_C| HM:PFM:NREP 7 HM:PFM:REP 33->496|PF00521|4.6e-158|52.6|422/426|DNA_topoisoIV| HM:PFM:REP 529->567|PF03989|4.2e-09|25.6|39/50|DNA_gyraseA_C| HM:PFM:REP 582->624|PF03989|0.00029|22.5|40/50|DNA_gyraseA_C| HM:PFM:REP 639->683|PF03989|2.1e-08|24.4|45/50|DNA_gyraseA_C| HM:PFM:REP 686->734|PF03989|3.3e-15|39.6|48/50|DNA_gyraseA_C| HM:PFM:REP 785->833|PF03989|2.4e-10|22.9|48/50|DNA_gyraseA_C| HM:PFM:REP 835->882|PF03989|3.9e-17|35.4|48/50|DNA_gyraseA_C| GO:PFM:NREP 20 GO:PFM GO:0003677|"GO:DNA binding"|PF00521|IPR002205| GO:PFM GO:0003918|"GO:DNA topoisomerase (ATP-hydrolyzing) activity"|PF00521|IPR002205| GO:PFM GO:0005524|"GO:ATP binding"|PF00521|IPR002205| GO:PFM GO:0005694|"GO:chromosome"|PF00521|IPR002205| GO:PFM GO:0006265|"GO:DNA topological change"|PF00521|IPR002205| GO:PFM GO:0003677|"GO:DNA binding"|PF03989|IPR006691| GO:PFM GO:0003916|"GO:DNA topoisomerase activity"|PF03989|IPR006691| GO:PFM GO:0005524|"GO:ATP binding"|PF03989|IPR006691| GO:PFM GO:0005694|"GO:chromosome"|PF03989|IPR006691| GO:PFM GO:0006265|"GO:DNA topological change"|PF03989|IPR006691| GO:PFM GO:0003677|"GO:DNA binding"|PF03989|IPR006691| GO:PFM GO:0003916|"GO:DNA topoisomerase activity"|PF03989|IPR006691| GO:PFM GO:0005524|"GO:ATP binding"|PF03989|IPR006691| GO:PFM GO:0005694|"GO:chromosome"|PF03989|IPR006691| GO:PFM GO:0006265|"GO:DNA topological change"|PF03989|IPR006691| GO:PFM GO:0003677|"GO:DNA binding"|PF03989|IPR006691| GO:PFM GO:0003916|"GO:DNA topoisomerase activity"|PF03989|IPR006691| GO:PFM GO:0005524|"GO:ATP binding"|PF03989|IPR006691| GO:PFM GO:0005694|"GO:chromosome"|PF03989|IPR006691| GO:PFM GO:0006265|"GO:DNA topological change"|PF03989|IPR006691| RP:SCP:NREP 2 RP:SCP:REP 31->512|1ab4A|e-160|57.5|471/477|e.11.1.1| RP:SCP:REP 525->882|1wp5A|1e-86|24.2|302/323|b.68.10.1| HM:SCP:REP 1->516|1bjtA_|1.2e-180|56.1|474/760|e.11.1.1|1/1|Type II DNA topoisomerase| HM:SCP:REP 524->900|1wp5A_|6.7e-97|46.1|321/0|b.68.10.1|1/1|GyrA/ParC C-terminal domain-like| OP:NHOMO 1983 OP:NHOMOORG 1127 OP:PATTERN -----------------------111111111-----------1111111111--------111---- 1111211111111111112-12111211111122221111211122222222222222222222221222222222221111111111222212222112222222222222222222222222211111111111111111111122222222222222222222222222222222222221111111112222222222222222222222222222212222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222212122222222222221222222222111221122111121111111111112222222222222222222222222222222222-22223222222222222222222222222222222222222222222222222221111111111112222222222222111112222222222222222222222222222222232222222222222222222222221121222222222111222112121111111111111111111111122111111111111111111111111111222223222222222222222222222222221-2222211111122222222222222222-22222222222222222222222222222222222222222222222222221222222222222112222222222222222222222222112222222122222222222222222222222222222222222222222222222322222222222222222212222222222222221211112-22222222222222222231111111111122 221122116221112111111111111111111111111121111111111111111111111-1111-1111-1111111-111111-1211111111112111111222221334112122122-319I2-42621-12-223221121113-422113912121111-44-13222F2232232111233443222 ---1---------------1---------------111-1----------------------------------------------------------------------------------------------------------------------------------1-1-- STR:NPRED 883 STR:RPRED 97.6 SQ:SECSTR HHHHHHHcccccccccccTHHHHHHHHHHHcTTTcccTTTcccHHHHHHHHHHHHTTcccccccEEHHHHHHHHHHHTccccHHHHHHHHHHTTcTTTcccccEEEEcccccTTccccccTTTcEEEEcTTHHHHcTTTTTTcccEEEcTTcccEEEccccccccHHHHHcEEEccccccEEEccccHHHHHHHHHHHHHcTTccHHHHTTTccccccccccEEcccHHHHHHHHHcEEEEEEEcEEEEEHHcEEccEEEEEEccTTccHHHHHHHHHHHHTTTcccccccEEEccccccccEEEcccHHHHHHHHHHHHHHHcTTEEEEEEEcEEEETTEEEEccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHcccHHHHHHHHHHccEEccGGGTTcccccccTTccTTcEEEccHHHHHHHHTccGGGGcHHHHHHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHccccccEEHHHHHHHHHHccGGGcccEEEEccGGGHHHcccTGGGEHHHHTTTcTTcEEEEEcccccGGGGGGcHHHHHHccEEEEEETTTTGGGTccHHHHHHHHHHHHHHHHcHHHHEEEEEEEEEcccccTHHHTcccTTccccTTccccccEcHHHHHHHHHHHHHHHHHHHHHHHTccGGGcHHHHHHHHHTccccHHHcHHHccccEEEEcccccccccccccccEEEcTTcEEEEEGGGcccccTTcccEEccccccccccccEEEHHHcHHHHHHHTcccTTccccTTccccGEEcccHHHHHHHHHHHHHHHHHHHHHHHTccGGGccHHHHHHHHETTEEEEEEEEEccccEEEEEEcccEEEcTTccE###################### DISOP:02AL 1-6, 550-560, 888-905| PSIPRED ccccccccEEEccHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHcccccccccEEHHHHHHHHHHHccccHHHHHHHHHHHHcccHHccccEEcccccccccccccccccccHHHHHHHHHHHHHHHccccccccEEcccccccccEEEcccccEEEEEcccEEEEccccccccccHHHHHHHHHHHHccccccHHHHHHHccccccccccEEEccHHHHHHHHcccEEEEEEEEEEEEEcccccEEEEEEEccccccHHHHHHHHHHHHHcccccHHHHHHHHcccccEEEEEEEcccccHHHHHHHHHHHccEEEEEEEEEEEEcccEEEEccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHccccccHHHHHHHHccHHHHHcccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHccccccHHHHccccccHHHHcccccEEEEEccccEEEEccHHHHHHccccccccccccccccccEEEEEEEEcccEEEEEEccccEEEEEHHHccccccccccEEEEEccccccccEEEEEEEEccccccccccEEEEEEcccEEEEEEHHHHcccccccEEEEEcccccEEEEEEEEccccEEEEEEccccEEEEEHHHcccccccccccEEEEEEccccEEEEEEEEcccccccccHHHcccccHHHHHHHHcccccccccccccccEEEEEEEcccccEEEEEEcccEEEEccHHHcccccccccEEEEEEEEccccEEEEEEEEcccccEEEEEcccEEEEEEHHHcccccccccccEEEEEccccEEEEEEEEccccccccccccccccccccccc //