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Rickettsia conorii str. Malish 7 (rcon0)
Gene : icd
DDBJ      :icd          isocitrate dehydrogenase
Swiss-Prot:IDH_RICCN    RecName: Full=Isocitrate dehydrogenase [NADP];         Short=IDH;         EC=1.1.1.42;AltName: Full=Oxalosuccinate decarboxylase;AltName: Full=NADP(+)-specific ICDH;AltName: Full=IDP;

Homologs  Archaea  60/68 : Bacteria  775/915 : Eukaryota  189/199 : Viruses  0/175   --->[See Alignment]
c.77.1
:483 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   7->483 2d1cA PDBj 7e-95 41.3 %
:RPS:PDB   6->344 3blwM PDBj 9e-92 37.0 %
:RPS:SCOP  7->341 1ai2A  c.77.1.1 * 5e-90 34.0 %
:HMM:SCOP  1->341 1pb1A_ c.77.1.1 * 9.8e-112 45.6 %
:RPS:PFM   7->326 PF00180 * Iso_dh 3e-72 47.3 %
:HMM:PFM   7->337 PF00180 * Iso_dh 4.2e-97 40.8 326/347  
:HMM:PFM   419->433 PF00301 * Rubredoxin 0.00085 46.7 15/47  
:BLT:SWISS 1->483 IDH_RICCN 0.0 100.0 %
:PROS 228->247|PS00470|IDH_IMDH

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAL02891.1 GT:GENE icd GT:PRODUCT isocitrate dehydrogenase GT:DATABASE GIB00062CH01 GT:ORG rcon0 GB:ACCESSION GIB00062CH01 GB:LOCATION 355167..356618 GB:FROM 355167 GB:TO 356618 GB:DIRECTION + GB:GENE icd GB:PRODUCT isocitrate dehydrogenase GB:PROTEIN_ID AAL02891.1 GB:DB_XREF GI:15619416 GB:GENE:GENE icd LENGTH 483 SQ:AASEQ MAEFTPITIAYGDGIGPEIMEAVLYILRKAEARIRLETIEVGEKLYKKHYTSGISEESWESIQRTGIILKAPITTPQGGGYKSLNVTIRKTLQLFANIRPAVSLHPFTRTLHPNLNLTIIRENEEDLYAGIEYRQTHNMYESMKLISHTGCEKIIRYAFEYAVKNNRKKVMCLSKDNIMKFSDGVLHKVFNEIAKEYPQINNAHYIIDIGTARLATKPEIFDVIVTSNLYGDIISDVAAEISGSVGLAGSANIGQHYAMFEAVHGSAPDIAGKDIANPSGLLNAAIMMLVHIGQGDIATLIENAWKKTIEDGVHTADIYNEQSSSKKVGTKEFAEEVTKRLGQLPTKLPKADYPLIAEKQESNIDYKIDTKEVKKLVGTDIFVNMNVSSAHDIADKINKLDLGNFELKTISSKGLKLWPRDTRFETVSDHWCCRFMNKDGTEIKHLDITRLLEALSTANIDFIKVENLFEFDGVAGYSLAQGE GT:EXON 1|1-483:0| SW:ID IDH_RICCN SW:DE RecName: Full=Isocitrate dehydrogenase [NADP]; Short=IDH; EC=1.1.1.42;AltName: Full=Oxalosuccinate decarboxylase;AltName: Full=NADP(+)-specific ICDH;AltName: Full=IDP; SW:GN Name=icd; OrderedLocusNames=RC0353; SW:KW Complete proteome; Glyoxylate bypass; Magnesium; Manganese;Metal-binding; NADP; Oxidoreductase; Phosphoprotein;Tricarboxylic acid cycle. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->483|IDH_RICCN|0.0|100.0|483/483| GO:SWS:NREP 5 GO:SWS GO:0006097|"GO:glyoxylate cycle"|Glyoxylate bypass| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| GO:SWS GO:0006099|"GO:tricarboxylic acid cycle"|Tricarboxylic acid cycle| PROS 228->247|PS00470|IDH_IMDH|PDOC00389| BL:PDB:NREP 1 BL:PDB:REP 7->483|2d1cA|7e-95|41.3|470/495| RP:PDB:NREP 1 RP:PDB:REP 6->344|3blwM|9e-92|37.0|322/339| RP:PFM:NREP 1 RP:PFM:REP 7->326|PF00180|3e-72|47.3|319/338|Iso_dh| HM:PFM:NREP 2 HM:PFM:REP 7->337|PF00180|4.2e-97|40.8|326/347|Iso_dh| HM:PFM:REP 419->433|PF00301|0.00085|46.7|15/47|Rubredoxin| GO:PFM:NREP 4 GO:PFM GO:0000287|"GO:magnesium ion binding"|PF00180|IPR001804| GO:PFM GO:0016616|"GO:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"|PF00180|IPR001804| GO:PFM GO:0051287|"GO:NAD or NADH binding"|PF00180|IPR001804| GO:PFM GO:0055114|"GO:oxidation reduction"|PF00180|IPR001804| RP:SCP:NREP 1 RP:SCP:REP 7->341|1ai2A|5e-90|34.0|335/414|c.77.1.1| HM:SCP:REP 1->341|1pb1A_|9.8e-112|45.6|340/0|c.77.1.1|1/1|Isocitrate/Isopropylmalate dehydrogenase-like| OP:NHOMO 2517 OP:NHOMOORG 1024 OP:PATTERN 11-2--2222222222-2222222211222222222222222222222323332221-1--2112-22 4443111111111221111-111113111111133322531111211-1111121111--111-13411111111111-22-422121222212---11--2-1121131--------------111111111121333332225322322222222222222122222322222222222223333311142322222222322222243333322232433112222223212222222222222222222-------2------------11-221-------222-1111111111-------------222222222-23-21111111111132221---2-21-411222211222-221112--32221111-1--1117441132222111111111111-23422433222-3222225424221111131241342112222222253322221111111111111111111111111111111131123543445554433333554533331333745532222553444444774333222212111111122223312321222222222-111111132222234131111111111-1111111111211122332221312312222222222222222222-1-2532-11--132332223332322233-3323322333323333333344222322222222222222222233322231-233333333333111111111222224232111113-111-2112333331212111222233232232323431-1--1---111121111111111222222222222222211112222-------------------------------------22--1-111212 ----225-21--3347865778688876645555555555455444546777676664444433444434424442433344444424-46484456564426667-3235593333333227333242Ff6-6452333823642333332166313536424335B3784463333191112374986A31121111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 482 STR:RPRED 99.8 SQ:SECSTR ccccEEEEEEccTTTHHHHHHHHHHHHHTTTccEEEEEccccTTccHHHccccTHHHHHHHHHHHcEEEEccccccccTccccccHHHHHHHTccEEEEEEEcccTTccccccccEEEEEEEcccEEEEEEEEEccTTcEEEEEEccHHHHHHHHHHHHHHHHHTTccEEEEEEcTTTcTTHHHHHHHHHHHHHcccTTcEEEEEEHHHHHHHHHHcGGGccEEEEcHHHHHHHHHHHHHHHTcGGGcEEEEEccccEEEcccccccGGGTTccccccHHHHHHHHHHHHHTTccHHHHHHHHHHHHHHHcccccGGGTTTcTTTccccHHHHHHHHHHHHTTcccccccccccccccccGGGccccccccccEEEEEEEEEEEccccHHHHHHHHHHHHTTccEEEEEEEETTEEEEcccccccccccEEEEEEEEcccccccHHHHHHHHHHHH#TTcEEEEEEEEEEETTEEccccccTc DISOP:02AL 1-2, 358-363, 481-483| PSIPRED cccccEEEEEccccccHHHHHHHHHHHHHccccEEEEEEEccHHHHHHcccccccHHHHHHHHHccEEEEcccccccccccccHHHHHHHHHccEEEEEEEEEcccccccccccccEEEEEEccccEEEcccEEcccccEEEEEEEcHHHHHHHHHHHHHHHHHccccEEEEEEcHHHHHHHHHHHHHHHHHHHHHccccEEEHHHHHHHHHHHHHcccccEEEEEccccHHHHHHHHHHHHccHHHcccEEEcccccEEEEcccccccccccccccHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHcccccHHHcccccccccccHHHHHHHHHHHHHHHHHHcccccccccccccccccccEEccccccEEEEEEEEEEEccccHHHHHHHHccccccccEEEEEEcccEEEEcccccccEEEEEEEEEEEEcccccccHHHHHHHHHHHHHccccEEEEEEEEEEcccccccccccc //