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Rickettsia conorii str. Malish 7 (rcon0)
Gene : ksgA
DDBJ      :ksgA         dimethyladenosine transferase
Swiss-Prot:KSGA_RICCN   RecName: Full=Dimethyladenosine transferase;         EC=2.1.1.-;AltName: Full=S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase;AltName: Full=16S rRNA dimethylase;AltName: Full=High level kasugamycin resistance protein ksgA;AltName: Full=Kasugamycin dimethyltransferase;

Homologs  Archaea  47/68 : Bacteria  878/915 : Eukaryota  183/199 : Viruses  0/175   --->[See Alignment]
c.66.1
:315 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   36->315 1qyrA PDBj 2e-36 40.1 %
:RPS:PDB   34->313 2aztA PDBj 7e-15 5.7 %
:RPS:SCOP  36->315 1qyrA  c.66.1.24 * 4e-55 39.7 %
:HMM:SCOP  28->316 1i4wA_ c.66.1.24 * 1e-77 41.7 %
:RPS:PFM   32->315 PF00398 * RrnaAD 1e-49 45.4 %
:HMM:PFM   32->315 PF00398 * RrnaAD 6.3e-56 31.1 251/262  
:BLT:SWISS 15->315 KSGA_RICCN e-171 100.0 %
:PROS 60->88|PS01131|RRNA_A_DIMETH

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAL03560.1 GT:GENE ksgA GT:PRODUCT dimethyladenosine transferase GT:DATABASE GIB00062CH01 GT:ORG rcon0 GB:ACCESSION GIB00062CH01 GB:LOCATION complement(948447..949394) GB:FROM 948447 GB:TO 949394 GB:DIRECTION - GB:GENE ksgA GB:PRODUCT dimethyladenosine transferase GB:PROTEIN_ID AAL03560.1 GB:DB_XREF GI:15620139 GB:GENE:GENE ksgA LENGTH 315 SQ:AASEQ MFYWIPAFTGMTYPMLPSIAKHAALHQVNPLKKHGQNFIFDSSLCDKIVRASNLAENSRVLEIGPGTGGLTRSILQKNPESLTVIETDARCLPLLNEIKEYYPNLNIIKQDALKINLTDLSYDIVNSVGFAYKKREVKPITNRRANDIGESKSIDYKVTIISNLPYHIGTELVIRWLKEARLITSMTLMLQKEVVERICAIPSTKAYGRLSVICQLIAKVEKCFDVAPTAFYPPPKVYSAIVKLIPLENPPSIALINKVEQITKLAFAGRRKMIKSSLKNLVPNIYEVLTQLKINDNYRAENLAPQDYLRIAEIL GT:EXON 1|1-315:0| SW:ID KSGA_RICCN SW:DE RecName: Full=Dimethyladenosine transferase; EC=2.1.1.-;AltName: Full=S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase;AltName: Full=16S rRNA dimethylase;AltName: Full=High level kasugamycin resistance protein ksgA;AltName: Full=Kasugamycin dimethyltransferase; SW:GN Name=ksgA; OrderedLocusNames=RC1022; SW:KW Antibiotic resistance; Complete proteome; Methyltransferase;RNA-binding; rRNA processing; S-adenosyl-L-methionine; Transferase. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 15->315|KSGA_RICCN|e-171|100.0|301/301| GO:SWS:NREP 5 GO:SWS GO:0046677|"GO:response to antibiotic"|Antibiotic resistance| GO:SWS GO:0008168|"GO:methyltransferase activity"|Methyltransferase| GO:SWS GO:0003723|"GO:RNA binding"|RNA-binding| GO:SWS GO:0006364|"GO:rRNA processing"|rRNA processing| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 60->88|PS01131|RRNA_A_DIMETH|PDOC00871| BL:PDB:NREP 1 BL:PDB:REP 36->315|1qyrA|2e-36|40.1|247/252| RP:PDB:NREP 1 RP:PDB:REP 34->313|2aztA|7e-15|5.7|245/276| RP:PFM:NREP 1 RP:PFM:REP 32->315|PF00398|1e-49|45.4|251/256|RrnaAD| HM:PFM:NREP 1 HM:PFM:REP 32->315|PF00398|6.3e-56|31.1|251/262|RrnaAD| GO:PFM:NREP 3 GO:PFM GO:0000154|"GO:rRNA modification"|PF00398|IPR001737| GO:PFM GO:0000179|"GO:rRNA (adenine-N6,N6-)-dimethyltransferase activity"|PF00398|IPR001737| GO:PFM GO:0008649|"GO:rRNA methyltransferase activity"|PF00398|IPR001737| RP:SCP:NREP 1 RP:SCP:REP 36->315|1qyrA|4e-55|39.7|247/252|c.66.1.24| HM:SCP:REP 28->316|1i4wA_|1e-77|41.7|264/0|c.66.1.24|1/1|S-adenosyl-L-methionine-dependent methyltransferases| OP:NHOMO 1228 OP:NHOMOORG 1108 OP:PATTERN --1111----------1111111111111-11-1111-111111111111111111111111------ 1111111111111-11111-111111111111111111111----1111---11111111--111111---111111111111-111111111111-111111111111111111111111111111111111111---1111--111111111111-1--1-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111311111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111----111111111111111111-1111111111111111111111111-111-11 22-1221-411122111111111111111-1111111111111111-111--1-11--111-111111111111111-1111111111-1211111111111122212-2432223-222122222122272-2222122221312221222232222211221221423-42232121D2221222321222231112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 312 STR:RPRED 99.0 SQ:SECSTR ###GGGccccccccccccHHcccEEEEETTcTcHTccccccHHHHHHHHHHHHHTTccEEEEcccTTcHHHHHHGGGccEEEEEcccHHHHTcEEEEEEccHHHHHHHHHHHHHTTTcHccccccHHHHHHHEEEEEEccHHHHcEEEEccGGGHHHHccccccEEEEEEccccGGGccccccccHHHHHHHHHHHHTEEEEEEEEEEEEcHHHHHHHTccccccccccccccccEEEEEEEEETTEEEEEEEEEEccccEEEEEEccccHHHHHHHHHHHHTTcEEEEEEETTEEccTTccccccEEEEEEEHH PSIPRED ccccHHHHccccccccccHHHHHHHHcccccccccccccccHHHHHHHHHHcccccccEEEEEcccccHHHHHHHHHcccEEEEEEccHHHHHHHHHHHcccccEEEEEccEEcccccHHHHHHHHHcccccccHHHccccccHHHHccccccccccEEEEEcccccHHHHHHHHHHcccccccEEEEEEHHHHHHHHHcccccccccHHHHHHHHHEEEEEEEEEcHHHcccccccEEEEEEEEEcccccccccHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHcccccccccEEccHHHHHHHHHcc //