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Ralstonia metallidurans CH34 (rmet0)
Gene : ABF07717.1
DDBJ      :             alanyl-tRNA synthetase
Swiss-Prot:SYA_RALME    RecName: Full=Alanyl-tRNA synthetase;         EC=6.1.1.7;AltName: Full=Alanine--tRNA ligase;         Short=AlaRS;

Homologs  Archaea  67/68 : Bacteria  907/915 : Eukaryota  195/199 : Viruses  0/175   --->[See Alignment]
a.203.1b.43.3d.104.1d.206.1d.67.1
:884 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   10->472 1yfrA PDBj e-137 56.2 %
:BLT:PDB   574->691 1wnuB PDBj 9e-09 34.8 %
:RPS:PDB   13->459 2cvsA PDBj 1e-85 12.6 %
:RPS:PDB   463->706 2e1bA PDBj 5e-39 23.9 %
:RPS:PDB   683->882 3c9iF PDBj 8e-20 12.1 %
:RPS:SCOP  10->261 1riqA2  d.104.1.1 * e-130 63.1 %
:RPS:SCOP  262->472 1riqA1  a.203.1.1 * 7e-69 41.3 %
:RPS:SCOP  463->555 2e1bA1  b.43.3.6 * 1e-14 26.0 %
:RPS:SCOP  573->707 1v4pA  d.67.1.2 * 1e-37 27.4 %
:RPS:SCOP  771->840 1jrmA  d.206.1.1 * 2e-10 14.9 %
:HMM:SCOP  10->261 1riqA2 d.104.1.1 * 8.1e-109 69.5 %
:HMM:SCOP  262->477 1riqA1 a.203.1.1 * 2.8e-64 41.7 %
:HMM:SCOP  562->732 1nyrA3 d.67.1.1 * 1.4e-48 43.8 %
:RPS:PFM   15->555 PF01411 * tRNA-synt_2c 0.0 62.3 %
:RPS:PFM   663->704 PF07973 * tRNA_SAD 1e-07 54.8 %
:RPS:PFM   808->878 PF02272 * DHHA1 1e-06 41.8 %
:HMM:PFM   15->564 PF01411 * tRNA-synt_2c 1.1e-222 56.4 539/551  
:HMM:PFM   663->705 PF07973 * tRNA_SAD 4.2e-19 62.8 43/44  
:HMM:PFM   810->877 PF02272 * DHHA1 9.2e-17 35.4 65/68  
:HMM:PFM   743->808 PF06009 * Laminin_II 9.5e-05 23.8 63/140  
:HMM:PFM   716->764 PF12329 * TMF_DNA_bd 0.00046 30.6 49/74  
:BLT:SWISS 11->884 SYA_RALME 0.0 100.0 %
:COIL
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABF07717.1 GT:GENE ABF07717.1 GT:PRODUCT alanyl-tRNA synthetase GT:DATABASE GIB00349CH01 GT:ORG rmet0 GB:ACCESSION GIB00349CH01 GB:LOCATION 905964..908618 GB:FROM 905964 GB:TO 908618 GB:DIRECTION + GB:PRODUCT alanyl-tRNA synthetase GB:PROTEIN_ID ABF07717.1 GB:DB_XREF GI:93353628 InterPro:IPR002318 InterPro:IPR003156 InterPro:IPR012947 LENGTH 884 SQ:AASEQ MPRRRLRPHNMKVSDIRSKFLQFFESKGHTVVRSSSLVPANDPTLLFTNSGMVQFKDVFLGTDKRPYVRATSSQRSVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKREAIQYAWELLTKVYQLPADKLWVTVYAEDDEAYDIWAKEVGVPADRIVRIGDNKGARYASDNFWQMADTGPCGPCSEIFYDHGPDVWGGPPGSPEEDGDRYIEIWNLVFMQFNRDEQGTMTPLPKPCVDTGMGLERIAAVLQHVHSNYEIDLFQALIKGAGRETHIADLNQNSLKVIADHIRACSFLIVDGVIPGNEGRGYVLRRIVRRAIRHGYKLGQKTPFFHKLVGDLVAQMGEAYPELAEAQSRVVEVLKAEEERFFETIENGMSILDAAVADLKAKGGKVLDGELAFKLHDTFGFPLDLTQDVAREQEITVDEAAFDAAMTRQREQARAAGKFKMAAGLEYSGEKTVFHGYDALSMDGVRVTALYVDGASVDTMQPGQSGVVVLDNTPFYAESGGQVGDQGTLVSGPAVFAVADTTKIQSDVFGHQGTLANGALKVGDTVAAQVDAVRRARTVRNHSATHLMHKALREVLGTHVQQKGSLVDPDKTRFDFSHNAPLTDAQIRQIEEIVNAEILSNAPTVAQVMPFDDAVKSGAMALFGEKYADDVRVLSIGTSKELCGGTHVTRTGDIGLFKIVVEAGVAAGIRRVEAITGDNALHYLQSLDARLNEAAAALRAQPSELVPRIGQVQDQVRALEKELEKLKSKLASSQGDELAAQAVDVKGLKVLAAQLDGADVKTLRETMDKLKDKLQSAAIVLAAVADGKVSLIAGVTADATSKVKAGELVNFVAQQVGGKGGGRPDMAQAGGTDPANLPKALAGVTEWVSAKV GT:EXON 1|1-884:0| SW:ID SYA_RALME SW:DE RecName: Full=Alanyl-tRNA synthetase; EC=6.1.1.7;AltName: Full=Alanine--tRNA ligase; Short=AlaRS; SW:GN Name=alaS; OrderedLocusNames=Rmet_0831; SW:KW Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm;Ligase; Nucleotide-binding; Protein biosynthesis. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 11->884|SYA_RALME|0.0|100.0|874/874| GO:SWS:NREP 6 GO:SWS GO:0004812|"GO:aminoacyl-tRNA ligase activity"|Aminoacyl-tRNA synthetase| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006412|"GO:translation"|Protein biosynthesis| COIL:NAA 33 COIL:NSEG 1 COIL:REGION 740->772| SEG 201->212|ggppgspeedgd| SEG 556->572|dtvaaqvdavrrartvr| SEG 721->732|arlneaaaalra| SEG 750->765|alekeleklksklass| BL:PDB:NREP 2 BL:PDB:REP 10->472|1yfrA|e-137|56.2|438/448| BL:PDB:REP 574->691|1wnuB|9e-09|34.8|112/149| RP:PDB:NREP 3 RP:PDB:REP 13->459|2cvsA|1e-85|12.6|435/657| RP:PDB:REP 463->706|2e1bA|5e-39|23.9|209/216| RP:PDB:REP 683->882|3c9iF|8e-20|12.1|198/221| RP:PFM:NREP 3 RP:PFM:REP 15->555|PF01411|0.0|62.3|523/546|tRNA-synt_2c| RP:PFM:REP 663->704|PF07973|1e-07|54.8|42/44|tRNA_SAD| RP:PFM:REP 808->878|PF02272|1e-06|41.8|67/67|DHHA1| HM:PFM:NREP 5 HM:PFM:REP 15->564|PF01411|1.1e-222|56.4|539/551|tRNA-synt_2c| HM:PFM:REP 663->705|PF07973|4.2e-19|62.8|43/44|tRNA_SAD| HM:PFM:REP 810->877|PF02272|9.2e-17|35.4|65/68|DHHA1| HM:PFM:REP 743->808|PF06009|9.5e-05|23.8|63/140|Laminin_II| HM:PFM:REP 716->764|PF12329|0.00046|30.6|49/74|TMF_DNA_bd| GO:PFM:NREP 12 GO:PFM GO:0000166|"GO:nucleotide binding"|PF01411|IPR018164| GO:PFM GO:0004813|"GO:alanine-tRNA ligase activity"|PF01411|IPR018164| GO:PFM GO:0005524|"GO:ATP binding"|PF01411|IPR018164| GO:PFM GO:0005737|"GO:cytoplasm"|PF01411|IPR018164| GO:PFM GO:0006412|"GO:translation"|PF01411|IPR018164| GO:PFM GO:0006419|"GO:alanyl-tRNA aminoacylation"|PF01411|IPR018164| GO:PFM GO:0005524|"GO:ATP binding"|PF07973|IPR012947| GO:PFM GO:0005737|"GO:cytoplasm"|PF07973|IPR012947| GO:PFM GO:0006412|"GO:translation"|PF07973|IPR012947| GO:PFM GO:0016876|"GO:ligase activity, forming aminoacyl-tRNA and related compounds"|PF07973|IPR012947| GO:PFM GO:0043039|"GO:tRNA aminoacylation"|PF07973|IPR012947| GO:PFM GO:0003676|"GO:nucleic acid binding"|PF02272|IPR003156| RP:SCP:NREP 5 RP:SCP:REP 10->261|1riqA2|e-130|63.1|236/236|d.104.1.1| RP:SCP:REP 262->472|1riqA1|7e-69|41.3|208/212|a.203.1.1| RP:SCP:REP 463->555|2e1bA1|1e-14|26.0|77/87|b.43.3.6| RP:SCP:REP 573->707|1v4pA|1e-37|27.4|135/151|d.67.1.2| RP:SCP:REP 771->840|1jrmA|2e-10|14.9|67/104|d.206.1.1| HM:SCP:REP 10->261|1riqA2|8.1e-109|69.5|236/0|d.104.1.1|1/1|Class II aaRS and biotin synthetases| HM:SCP:REP 262->477|1riqA1|2.8e-64|41.7|216/0|a.203.1.1|1/1|Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)| HM:SCP:REP 562->732|1nyrA3|1.4e-48|43.8|169/179|d.67.1.1|1/1|ThrRS/AlaRS common domain| OP:NHOMO 1354 OP:NHOMOORG 1169 OP:PATTERN 11111111111111111111111121112211111111111111111121222111222211111-11 2111111111111111111-1111111111111111111111111111111111111111111111112211-111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111222221121111111112211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111112111111111111121111111111111111111111111112111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111-1111111111111111111111111222222111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111-111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111 1111241-31111111111-111111211111111111111111111111111111111111111111-2111111111111111111-12111111111111222123133332632221222242223F212222222221221222122223322122222332322322122222I2221222451212223222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 877 STR:RPRED 99.2 SQ:SECSTR ##cccEcHHHHHHHHHHHHHHHHHHTcccEEEEcTTcccTTccccccccccHHHHHHHHHHHHHHccTTcTTHHHHHTTHcTcccccccccccccccEEETEEEEEcHHHHHHHHTTcEEEEGGGccHHHHHHHHHHHHHTEEEHHHHHHHHHHHHHHHcccEEEEHHHHHHTcTTTTTcccccccTTccccccccTTEccccccccEEcHHHHHHHHHHHHHHHHHHHHHcccccHHHHcccEEEEEcHHHHHHHTTccTTcHHHHHHHHHHHHHHHHHHcccTTcTTcGGGGTccTGGGGTccccccccHHHHHHHHHHHcccccccccccccTTHHHHTTccccccccccHHHHTcEEcccEEcHHHHHHHHHTTcccHHHHHHHHHTTTTTcTTccHHHHHHTccTTcccHHHHHHHHHHHHTTccccccccccHHHHHHHHHHHHHTccEEEccEEEcccccTTccTTccEEEEEEEETTE#EEEcccccccccccccccccccccTTcccccEEETETTETEEEEEEEccTTcccEEEEEccGGGccccccEEEEEcHHHHHHHHHHHHHHHHHHHHHHHHHTTccEEEEccccccccccEEEEEEEccccTTHHHHTTcccccTcccccccccccccccccEEcccccTTTcTTHHHHHTccccccccccTTEEEEEEcccEEEEEEccEETTEEEEEEccHHHH#HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH#HHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccccEEETTEEEEcccccccccccccccccccccTTHHHHHHHHHHHHHHHH## DISOP:02AL 1-14,388-397,439-455,730-731,761-761,763-765,767-767| PSIPRED ccccccccccccHHHHHHHHHHHHHHcccEEcccccccccccccEEEEEcccccccccccccccccccccccHHHHHHcccccccHHHccccccHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHcccHHHEEEEEEcccHHHHHHHHHHccccHHHEEEccccccccccccccccccccccccccEEEEEEccccccccccccccccccEEEEEEEEEEEEEEEcccccEEEcccccccccccHHHHHHHHcccccccHHHHHHHHHHHHHHHHccccccccEEEHHHHHHHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHccccHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHccccccccccccccccccccccccccEEEEEEEEEEccEEEEEEccccEEEEEEcccccccccccccccEEEEEEccEEEEEEEEEEccccEEEEEEEEcccccccccEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccEEEcccccccEEEEEEEccccccHHHHHHHHHHHHHHHHccccEEEEEccHHHHHHcccHHHcccccccEEEEEEEccccccccccccccccccccEEEEEEEcccccEEEEEEEEcHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccEEEccEEEEEEEEccccHHHHHHHHHHHHHHcccEEEEEEEccccEEEEEEEEcHHHHccccHHHHHHHHHHHHcccccccHHHHccccccHHHHHHHHHHHHHHHHHcc //