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Ralstonia metallidurans CH34 (rmet0)
Gene : ABF08007.1
DDBJ      :             Hydrophobe/amphiphile efflux-1 HAE1
Swiss-Prot:             

Homologs  Archaea  0/68 : Bacteria  664/915 : Eukaryota  9/199 : Viruses  0/175   --->[See Alignment]
c.55.1d.225.1d.58.44f.35.1
:1044 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   1->1023 2v50B PDBj 0.0 41.2 %
:RPS:PDB   1->999 2dhhA PDBj 0.0 32.3 %
:RPS:SCOP  60->210 1mwkA2  c.55.1.1 * 6e-30 12.1 %
:RPS:SCOP  181->271 1iwgA5  d.225.1.1 * 6e-23 47.3 %
:RPS:SCOP  322->497 1iwgA7  f.35.1.1 * 8e-36 51.1 %
:RPS:SCOP  561->668 1iwgA3  d.58.44.1 * 7e-18 29.5 %
:RPS:SCOP  719->806 1iwgA6  d.225.1.1 * 8e-20 36.4 %
:RPS:SCOP  812->1024 1iwgA8  f.35.1.1 * 6e-33 40.4 %
:HMM:SCOP  38->133 1iwgA1 d.58.44.1 * 2.8e-24 38.5 %
:HMM:SCOP  134->329 1iwgA2 d.58.44.1 * 1.1e-20 32.4 %
:HMM:SCOP  295->497 1iwgA7 f.35.1.1 * 1.3e-47 42.5 %
:HMM:SCOP  561->652 1iwgA3 d.58.44.1 * 5.3e-12 33.7 %
:HMM:SCOP  669->853 1iwgA4 d.58.44.1 * 1.3e-19 37.4 %
:HMM:SCOP  801->1029 1iwgA8 f.35.1.1 * 8.2e-43 30.9 %
:RPS:PFM   1->1023 PF00873 * ACR_tran 0.0 38.9 %
:HMM:PFM   1->1022 PF00873 * ACR_tran 0 41.7 1011/1021  
:BLT:SWISS 1->1024 ACRD_ECOLI 0.0 43.0 %
:TM
:REPEAT 2|169->425|705->952
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABF08007.1 GT:GENE ABF08007.1 GT:PRODUCT Hydrophobe/amphiphile efflux-1 HAE1 GT:DATABASE GIB00349CH01 GT:ORG rmet0 GB:ACCESSION GIB00349CH01 GB:LOCATION complement(1224155..1227289) GB:FROM 1224155 GB:TO 1227289 GB:DIRECTION - GB:PRODUCT Hydrophobe/amphiphile efflux-1 HAE1 GB:PROTEIN_ID ABF08007.1 GB:DB_XREF GI:93353918 InterPro:IPR001036 InterPro:IPR004764 LENGTH 1044 SQ:AASEQ MAQFFLRRPAFAWVLAILTMVAGLVALNSIPVAQYPAVAPPTVILYADYPGATARTVEDRVTAVLEQQMHGIPGLLYIDSSSEAGTATVTIGFRQGTDPQLAQVNVRNRVSQAEPLLPEVVRRGGVYVDQASASPFMYVSLISKTGTMSETALADYAAGTVLPMLRRLPGIGKVEAYSAEYALRVWFNPDQLNAYGLTTADVEAAIRARNGSVTPGQLGGAPSKPGQSYQAVVRPPAPLADPEAFGRIVLRSAADGSAVLLRDVARVEMAAADYRYSSTLNGREAASMGLKLADGANVLATSRTVRDALDEAAKAFPAGVAYDISYDTAHFVQSSISRVLMTLAEATVLVFLILYLFLGNLRATLIPCIVVPVSLLGTVACLYAFGLSLNVITLFGVVLAIGILVDDAIVVVENVERIMREEGVDAFTAASRSMREVSGALLAVTLVLCAVFVPMAFLGSAVGVIYRHFAMTLAISIAFSLFFALSLAPAMCASLLRHGAQPARGPLAWFEHRFTAFTTRYAGWVQRLQQRRLRWLAVYLAMAAVCAVGLWQLPSGFLPEEDTGELVIDVELPPGSTQAQTRETIAQLEQWMKQERLPVKTSFALLGWNSGGSGEQRASVFLSLDDWKLRGRENAADVVLARLTKGLEEWPGRGDAQLYPYNGTALPELGSTSGLDMRLVTRLEGGRPSLYAARDKLIERAKADPVFAEVRATAGQPVPALDLAIDYRKAESFGVDTEAIHHALAATLGSRYIDELARDGRVRRVILQADAPFRMQPEDLARLHVRNAQGQMVSLGAFATLEWGNGEATLERYNGLISVRINADVAPGTSTGTAMTRLESLVRELGPDYEVRWSGRAFEQQQSGTQAPWLFALSMLFIFLCLVALYESWTLPLAVLAIVPAGLVGAASAVWLRGLPNDVYFKVGVIVIMGLAAKNAILVVEYAEQLRRNGLERVQAATQAARQRLRPVVMTSLAFILGVVPLAISTGPGAGAQRAVGTGVLGGMLGATILGTLVIPLLYAWIARWSKARATTEPAKAPASEPGA GT:EXON 1|1-1044:0| BL:SWS:NREP 1 BL:SWS:REP 1->1024|ACRD_ECOLI|0.0|43.0|1018/1037| TM:NTM 12 TM:REGION 10->32| TM:REGION 337->359| TM:REGION 366->388| TM:REGION 396->418| TM:REGION 437->459| TM:REGION 474->496| TM:REGION 534->556| TM:REGION 867->887| TM:REGION 891->913| TM:REGION 921->943| TM:REGION 967->989| TM:REGION 1000->1022| NREPEAT 1 REPEAT 2|169->425|705->952| SEG 440->453|allavtlvlcavfv| SEG 526->536|qrlqqrrlrwl| SEG 953->966|rvqaatqaarqrlr| BL:PDB:NREP 1 BL:PDB:REP 1->1023|2v50B|0.0|41.2|1019/1030| RP:PDB:NREP 1 RP:PDB:REP 1->999|2dhhA|0.0|32.3|987/1022| RP:PFM:NREP 1 RP:PFM:REP 1->1023|PF00873|0.0|38.9|1007/1014|ACR_tran| HM:PFM:NREP 1 HM:PFM:REP 1->1022|PF00873|0|41.7|1011/1021|ACR_tran| GO:PFM:NREP 3 GO:PFM GO:0005215|"GO:transporter activity"|PF00873|IPR001036| GO:PFM GO:0006810|"GO:transport"|PF00873|IPR001036| GO:PFM GO:0016020|"GO:membrane"|PF00873|IPR001036| RP:SCP:NREP 6 RP:SCP:REP 60->210|1mwkA2|6e-30|12.1|140/163|c.55.1.1| RP:SCP:REP 181->271|1iwgA5|6e-23|47.3|91/92|d.225.1.1| RP:SCP:REP 322->497|1iwgA7|8e-36|51.1|176/199|f.35.1.1| RP:SCP:REP 561->668|1iwgA3|7e-18|29.5|105/107|d.58.44.1| RP:SCP:REP 719->806|1iwgA6|8e-20|36.4|88/88|d.225.1.1| RP:SCP:REP 812->1024|1iwgA8|6e-33|40.4|213/222|f.35.1.1| HM:SCP:REP 38->133|1iwgA1|2.8e-24|38.5|96/0|d.58.44.1|1/1|Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains| HM:SCP:REP 134->329|1iwgA2|1.1e-20|32.4|102/0|d.58.44.1|1/1|Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains| HM:SCP:REP 295->497|1iwgA7|1.3e-47|42.5|200/200|f.35.1.1|1/2|Multidrug efflux transporter AcrB transmembrane domain| HM:SCP:REP 561->652|1iwgA3|5.3e-12|33.7|92/0|d.58.44.1|1/1|Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains| HM:SCP:REP 669->853|1iwgA4|1.3e-19|37.4|99/0|d.58.44.1|1/1|Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains| HM:SCP:REP 801->1029|1iwgA8|8.2e-43|30.9|220/223|f.35.1.1|2/2|Multidrug efflux transporter AcrB transmembrane domain| OP:NHOMO 4501 OP:NHOMOORG 673 OP:PATTERN -------------------------------------------------------------------- D9K-------------------------------------------11-1--111-11--11--1--1111------------44356FGIE-I24---23G4B8LBJ8C--------------342344533465111111--1-67455451122222534362E47A3-2-----2-----2111--11212222222222222221111212212112122------6311111111111111111111-----------------------------------------------------------------------6116-------1-1-1221--------1-13122522213-1-----31E3BG77C11111AENKRI9HLIJGD46574664547-NQGGPKML5A9-GAACBBDBBA8ABL7AA7495655544777777778CB866A61111111111--1-221141113311-111338936755BDHIGIBA7776CCGGAAAA7BDBHCGGN-5GHF7CA9BMFA7A7AGG9GAC8A111111187B6BF75A246764895531694779B77AA9AE92A62111222222333333333753598B875IE9JCDB6DEFFEHFKLFFHHDJQKMG--1B85B------76677B67999788A77-6887789768797777777CDC773456545666666546455A64664661-877777765778--17343335989H9C662111121111111117778759222A8DEEECCEFCDFEB99BC111111111A5AAB666669CDCBGHDADAA8BB54442297BC46BB11111111-----------------------------1---111118C6 -1-----------1------------------------------------------------------------------------------------------------------------------------------------------------6----6-2-------5-----------1--D-----7---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 1023 STR:RPRED 98.0 SQ:SECSTR cHHHHHHcTTTTTHHHHHHHHHHHHHHHHccccccccccccEEEEccccccccHHHHHTTTHHHHcTTcccccccccccEEEETccEEccEEccTTccHHHHHHHHHHHHHHHGGGccHHHHHHcccEEEccccccEEEEEEEccccccHHHHHHHHHHTTHHHHHccccccEEEEcccccccEEEEcHHHHHTTTccHHHHHHHHTTTcccccccccccccccTTcccccccccccccccHHHHHccEEEccTTTccEEHHHHEEEEccccccccEEEETTEEcccEEEEccccccHHHHHHHHHHHHTTTcccccccEEEEccccccHHHHHHHHHHHHHHHHHHHHHHHHHHTTccccTTTTHHHHHHHHHHHHHHHHHGGGTccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTcccccHHHHHHHHTTTcHHHHTTHHHHHHTTTTTccccccTTTHHHHHHHHHHHHHHHHHHHHTTTTHHHHcTTTcccTcccccHHHHTTTTTTTTHHHHHHHHHccccTTcTTTHHHHHHHHHHHHHHHHHccccccccccccEEEEEEEccTTccHHHHHHHHHHHHHTTccccTTEEEEEEEEEEccccEEEEEEEEEEEEccTTTccGGGcHHHHHHHHHHHTcccTTTTEcccEEEcccTTccccccccEEEEEEccccccTTHHHHHHHHHHHHHHccGGccccEEcccccEEcccccccHHHHHHTTccHHHHHHHHHHHHHcccccEEEccccEEEccccccGGGcccTTTGGGcEEEcTTccEEEGGGcccccccEEccEEEEETTEEEEEEEEcccccccHHHHHHHHHHHHHTccTTcEEEEcHHHHHHHcccccHHHHHHHHHHHHHHHHHHHTTcccTTHHHHTTHHHHHHHHcTTccccccccTTHHHHHHHHHHHHHHHHHHHHHHHHTTTTTccccTTTHHHHHHHTTHHHHHHHHHHHHHHHccTTTcccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH##################### DISOP:02AL 499-505,664-676,950-961,1025-1045| PSIPRED cHHHHHHccHHHHHHHHHHHHHHHHHHHcccHHHcccccccEEEEEEEEccccHHHHHHHHHHHHHHHHHccccEEEEEEEEEccEEEEEEEEEccccHHHHHHHHHHHHHHHHHHccccccccccEEEcccccEEEEEEEEcccccccHHHHHHHHHHHHHHHHHcccccEEEEEccccEEEEEEEcHHHHHHccccHHHHHHHHHHcccccccEEEEcccccccccEEEEEEEccccccHHHHHccEEEEcccccEEEEEEEEEEEEccccHHHEEEEccccEEEEEEEEcccccHHHHHHHHHHHHHHHHHHcccccEEEEEccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHcccEEEHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccccEEEEEEEccccccHHHHHHHHHHHHHHHHHccccEEEEEEEEEcccccccccEEEEEEEEEcHHHccccccHHHHHHHHHHHHHHccccccEEEEEEEccccccccccccccEEEEEEEcccHHHHHHHHHHHHHHHHccccEEEEEccccccccEEEEEEcHHHHHHccccHHHHHHHHHHHHccEEEEEEEEccEEEEEEEEEcHHHHccHHHHHccccccccccEEEEEEEEEEEEEccccEEEEEccEEEEEEEEEEcccccHHHHHHHHHHHHHHccccEEEEEcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccccccccc //