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Ralstonia metallidurans CH34 (rmet0)
Gene : ABF09677.1
DDBJ      :             dihydroxyacid dehydratase
Swiss-Prot:ILVD1_RALEJ  RecName: Full=Dihydroxy-acid dehydratase 1;         Short=DAD 1;         EC=4.2.1.9;

Homologs  Archaea  54/68 : Bacteria  742/915 : Eukaryota  117/199 : Viruses  0/175   --->[See Alignment]
c.8.2d.334.1
:557 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   73->526 2gp4A PDBj 6e-32 32.4 %
:RPS:PDB   31->297 2cwlB PDBj 5e-37 8.9 %
:RPS:PDB   337->527 3ejfA PDBj 4e-30 10.0 %
:RPS:SCOP  41->378 2gp4A2  d.334.1.1 * 8e-91 29.5 %
:RPS:SCOP  380->557 2gp4A1  c.8.2.2 * 1e-38 31.6 %
:HMM:SCOP  2->378 2gp4A2 d.334.1.1 * 9.4e-132 45.6 %
:HMM:SCOP  379->557 2gp4A1 c.8.2.2 * 2.3e-56 54.0 %
:RPS:PFM   35->554 PF00920 * ILVD_EDD e-158 53.8 %
:HMM:PFM   35->554 PF00920 * ILVD_EDD 8.6e-210 51.4 519/521  
:BLT:SWISS 1->557 ILVD1_RALEJ 0.0 93.7 %
:PROS 123->133|PS00886|ILVD_EDD_1
:PROS 465->476|PS00887|ILVD_EDD_2

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABF09677.1 GT:GENE ABF09677.1 GT:PRODUCT dihydroxyacid dehydratase GT:DATABASE GIB00349CH01 GT:ORG rmet0 GB:ACCESSION GIB00349CH01 GB:LOCATION 3051158..3052831 GB:FROM 3051158 GB:TO 3052831 GB:DIRECTION + GB:PRODUCT dihydroxyacid dehydratase GB:PROTEIN_ID ABF09677.1 GB:DB_XREF GI:93355588 InterPro:IPR000581 InterPro:IPR004404 LENGTH 557 SQ:AASEQ MAYNKRSQHITQGVARSPNRSMYYALGYKKEDFDKPMVGIANGHSTITPCNAGLQRLADAAVDAIKASDANPQIFGTPTISDGMSMGTEGMKYSLISREVIADCIETAAQGQWMDGVVVIGGCDKNMPGGMIALARTNVPGIYVYGGTIRPGNWKGKDLTIVSSFEAVGEFTAGRMSEEDFEGVEKNACPSTGSCGGMYTANTMSSSFEALGMSLLNSSTMANPDQEKVDSAAESARVLVEAIKKDIKPRDIITRKSIENAVTLIMATGGSTNAVLHYLAIAHSAEVEWTIDDFERIRRRVPVICNLKPSGAYVATDLHRAGGIPQVMKILLNAGLLHGDCLTITGRTLAEELEHVPNEPRTDQDVILPISQALYKQGHLAILKGNLAEEGAVAKITGLKNPVITGPARVFEDEQSAMEAILADKINAGDILVLRYLGPKGGPGMPEMLAPTSAIIGKGLGESVGFITDGRFSGGTWGMVVGHVAPEAHVGGTIALVQEGDSITIDAHQLLLQLNVADDELARRRAAWKQPAPRYTRGVLAKFARLASTASKGAVTD GT:EXON 1|1-557:0| SW:ID ILVD1_RALEJ SW:DE RecName: Full=Dihydroxy-acid dehydratase 1; Short=DAD 1; EC=4.2.1.9; SW:GN Name=ilvD1; OrderedLocusNames=Reut_A0639; SW:KW 4Fe-4S; Amino-acid biosynthesis;Branched-chain amino acid biosynthesis; Complete proteome; Iron;Iron-sulfur; Lyase; Metal-binding. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->557|ILVD1_RALEJ|0.0|93.7|557/557| GO:SWS:NREP 6 GO:SWS GO:0051539|"GO:4 iron, 4 sulfur cluster binding"|4Fe-4S| GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0009082|"GO:branched chain family amino acid biosynthetic process"|Branched-chain amino acid biosynthesis| GO:SWS GO:0051536|"GO:iron-sulfur cluster binding"|Iron-sulfur| GO:SWS GO:0016829|"GO:lyase activity"|Lyase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| PROS 123->133|PS00886|ILVD_EDD_1|PDOC00690| PROS 465->476|PS00887|ILVD_EDD_2|PDOC00690| BL:PDB:NREP 1 BL:PDB:REP 73->526|2gp4A|6e-32|32.4|410/509| RP:PDB:NREP 2 RP:PDB:REP 31->297|2cwlB|5e-37|8.9|237/298| RP:PDB:REP 337->527|3ejfA|4e-30|10.0|160/166| RP:PFM:NREP 1 RP:PFM:REP 35->554|PF00920|e-158|53.8|519/521|ILVD_EDD| HM:PFM:NREP 1 HM:PFM:REP 35->554|PF00920|8.6e-210|51.4|519/521|ILVD_EDD| GO:PFM:NREP 2 GO:PFM GO:0003824|"GO:catalytic activity"|PF00920|IPR000581| GO:PFM GO:0008152|"GO:metabolic process"|PF00920|IPR000581| RP:SCP:NREP 2 RP:SCP:REP 41->378|2gp4A2|8e-91|29.5|302/332|d.334.1.1| RP:SCP:REP 380->557|2gp4A1|1e-38|31.6|174/190|c.8.2.2| HM:SCP:REP 2->378|2gp4A2|9.4e-132|45.6|371/0|d.334.1.1|1/1|IlvD/EDD N-terminal domain-like| HM:SCP:REP 379->557|2gp4A1|2.3e-56|54.0|176/0|c.8.2.2|1/1|LeuD/IlvD-like| OP:NHOMO 1761 OP:NHOMOORG 913 OP:PATTERN 11-1--1111111111-11111111--11211111111111111111111211111-----1--1-11 2131211211111121111-121114111111211133332113242-211123111111121-23423211111111-11-111111111112---11--211211212---------------11111111111111111111111111111111111111111121111111111111111111111-11111111111111111121111111111111--1111111211111111111111111112---------------------1-111-------11111111111111-------------111222111-14-23111111111121112---2-1--1211122111111111111--12135444-22-2526771134543333333333225-33433537851-5554536666775522233423444342122222251122111-----------------------------2226222552746656452222557A222223447664512552325336463982211222212232222111311-2212111111111-1111111111111-3111111111112111111111111111222243323-2322322322233332222322-1-121111111122212314222422222-2232222222233223222222211123232323333323222322222221-22222222222211-------111122246111111-111111114444423111422222223322224333311-1-11-1121312222222123222222222222221111111111--------------------------------------1--1-111131 ------1-------134224464575622222222222222222222234334434333222111111111111111-1121111111-22242222222112222--5----------------------------------------------------------------1-1111I1111111352121132332 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 532 STR:RPRED 95.5 SQ:SECSTR #####################ccccccccccccccccccccc####cccccHHHHHHHGGGTTcTTcHHHHHHHcccTTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccTTccccccccccGGGcTTGGGGcccccHHHHTcccccccccTTcccccGGGccccccHHHHHHHHHHHHHHHHHHHHHHHTTcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccGGGGcccccccGGGcHHHTTTTEHHHHHTTTTcEEEEccccccTTcHHTTGGGTHHHHHHHHHHHHHHHHHHHHHHTcGGHHHHHHHHHcTTccccEEEGcHHHHHHHHHHHTTcccccccccccccccTccccccHHTcccccHHHHHHHHHHcHHHHHHHHHHHHHHHHHccccEEEEccccTTEEEEEEEccccTTcccHHHHHHHHHHTHHHHTcccETccTTEEEEEcccTTcTTccHHHHHHHHHHHHTTcccEEEccGGGcHHEEEccHHHHHHHHHccHHHHHHHHHHHHTTccEEEEccGGGTTc DISOP:02AL 1-3| PSIPRED cccccccccccccccHHHHHHHHHHccccHHHHcccEEEEEEcccccccccccHHHHHHHHHHHHHHcccEEEEcccccHHHcccccHHHHHHHHHHHHHHHHHHHHHHHcccccEEEEEccccccHHHHHHHHHHccccEEEEEcccccccccccEEccHHHHHHHHHHHHcccccHHHHHHHHHHccccccccccccHHHHHHHHHHHHHHccccccccccccHHHHHHHHHHHHHHHHHHHccccHHHHccHHHHHHHHHHHHHHcccHHHHHHHHHHHHHccccccHHHHHHHHccccEEEEcccccHHHHHHHHHcccHHHHHHHHHHcccccccccccccccHHHHHHHccccccccccccccHHHcccccccEEEEEcccccccEEEEEEcccccEEEEEEEEEccHHHHHHHHHccccccccEEEEEccccccccccHHHHHccHHHHHccccccccEEEcccccccccccccEEccHHHHccccEEEEEcccEEEEEccccEEEEEccHHHHHHHHHHccccccccccHHHHHHHHHcccHHHccccc //