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Rhodopseudomonas palustris BisB5 (rpal2)
Gene : ABE38903.1
DDBJ      :             PAS/PAC sensor hybrid histidine kinase
Swiss-Prot:             

Homologs  Archaea  30/68 : Bacteria  860/915 : Eukaryota  117/199 : Viruses  1/175   --->[See Alignment]
a.30.2c.23.1d.110.2d.110.3d.122.1f.55.1
:1427 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   360->581 3dgeA PDBj 9e-24 30.2 %
:BLT:PDB   650->765 2zwmA PDBj 1e-21 45.1 %
:BLT:PDB   805->894 3fg8E PDBj 9e-05 32.2 %
:BLT:PDB   1061->1284 3d36A PDBj 2e-23 28.9 %
:BLT:PDB   1307->1423 3jteA PDBj 8e-12 28.2 %
:RPS:PDB   57->184 3caxA PDBj 5e-06 11.6 %
:RPS:PDB   174->337 3dbaA PDBj 1e-08 9.2 %
:RPS:PDB   360->421 1csgA PDBj 2e-08 9.8 %
:RPS:PDB   408->776 1e51A PDBj 8e-41 10.1 %
:RPS:PDB   801->906 2cmnA PDBj 4e-14 22.6 %
:RPS:PDB   892->952 2btvA PDBj 2e-04 6.3 %
:RPS:PDB   987->1293 3d2rB PDBj 4e-30 11.9 %
:RPS:PDB   1307->1424 3cu5A PDBj 5e-16 20.2 %
:RPS:SCOP  57->184 2axtC1  f.55.1.1 * 2e-05 6.5 %
:RPS:SCOP  175->339 1mc0A1  d.110.2.1 * 3e-08 5.8 %
:RPS:SCOP  360->426 2c2aA1  a.30.2.1 * 3e-12 34.3 %
:RPS:SCOP  434->582 1b3qA3  d.122.1.3 * 1e-29 20.8 %
:RPS:SCOP  650->766 1a0oA  c.23.1.1 * 4e-32 36.8 %
:RPS:SCOP  801->1056 2axtC1  f.55.1.1 * 3e-17 8.5 %
:RPS:SCOP  1051->1120 1joyA  a.30.2.1 * 5e-08 18.6 %
:RPS:SCOP  1135->1282 1b3qA3  d.122.1.3 * 1e-21 18.6 %
:RPS:SCOP  1307->1419 1a0oA  c.23.1.1 * 2e-17 28.6 %
:HMM:SCOP  64->177 1dp6A_ d.110.3.2 * 2.6e-05 19.6 %
:HMM:SCOP  210->351 1mc0A2 d.110.2.1 * 9e-09 26.0 %
:HMM:SCOP  341->427 2c2aA1 a.30.2.1 * 5.3e-19 39.1 %
:HMM:SCOP  414->594 1jm6A2 d.122.1.4 * 1.1e-45 38.5 %
:HMM:SCOP  646->799 1s8nA_ c.23.1.1 * 1.3e-39 43.7 %
:HMM:SCOP  801->906 1dp6A_ d.110.3.2 * 1e-18 40.6 %
:HMM:SCOP  892->1034 1nwzA_ d.110.3.1 * 1.4e-13 33.6 %
:HMM:SCOP  1040->1126 2c2aA1 a.30.2.1 * 5.7e-14 26.4 %
:HMM:SCOP  1120->1288 1gkzA2 d.122.1.4 * 3.7e-39 36.1 %
:HMM:SCOP  1302->1419 1s8nA_ c.23.1.1 * 1.2e-25 40.0 %
:RPS:PFM   365->424 PF00512 * HisKA 2e-05 40.0 %
:RPS:PFM   478->581 PF02518 * HATPase_c 9e-18 43.1 %
:RPS:PFM   651->762 PF00072 * Response_reg 2e-23 50.0 %
:RPS:PFM   795->893 PF00989 * PAS 4e-07 34.3 %
:RPS:PFM   941->1044 PF08448 * PAS_4 1e-04 27.9 %
:RPS:PFM   1168->1283 PF02518 * HATPase_c 2e-16 37.5 %
:RPS:PFM   1307->1416 PF00072 * Response_reg 3e-13 34.8 %
:HMM:PFM   477->582 PF02518 * HATPase_c 3.4e-27 37.9 103/111  
:HMM:PFM   1166->1282 PF02518 * HATPase_c 9.9e-25 43.4 106/111  
:HMM:PFM   651->762 PF00072 * Response_reg 1.2e-30 44.5 110/112  
:HMM:PFM   1307->1389 PF00072 * Response_reg 1.7e-16 39.5 81/112  
:HMM:PFM   67->171 PF08448 * PAS_4 3.1e-05 20.0 100/110  
:HMM:PFM   796->898 PF08448 * PAS_4 5.1e-19 36.9 103/110  
:HMM:PFM   944->1044 PF08448 * PAS_4 6.9e-15 29.8 94/110  
:HMM:PFM   360->425 PF00512 * HisKA 4.1e-16 39.4 66/68  
:HMM:PFM   1060->1123 PF00512 * HisKA 4.2e-15 35.9 64/68  
:BLT:SWISS 77->200 YEGE_ECOLI 5e-04 32.8 %
:BLT:SWISS 360->581,648->761 DHKD_DICDI 2e-37 38.3 %
:BLT:SWISS 795->970 YQIR_BACSU 3e-04 27.7 %
:BLT:SWISS 1011->1419 LOVHK_PSE14 3e-63 37.4 %
:COIL
:REPEAT 2|94->772|823->1424
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID ABE38903.1 GT:GENE ABE38903.1 GT:PRODUCT PAS/PAC sensor hybrid histidine kinase GT:DATABASE GIB00345CH01 GT:ORG rpal2 GB:ACCESSION GIB00345CH01 GB:LOCATION complement(1875805..1880088) GB:FROM 1875805 GB:TO 1880088 GB:DIRECTION - GB:PRODUCT PAS/PAC sensor hybrid histidine kinase GB:PROTEIN_ID ABE38903.1 GB:DB_XREF GI:91682601 InterPro:IPR000014 InterPro:IPR000700 InterPro:IPR001789 InterPro:IPR003594 InterPro:IPR003661 InterPro:IPR004358 InterPro:IPR005467 LENGTH 1427 SQ:AASEQ MADVEWPGSSPGRGAAGHETLFLGRSELTSLLRRFDWAATPLGPPEQWPQALKTAVRIMLTSQQPIWIGWGEQLTYFYNDPYKAIIGGKHPWALGRPTREVWHEIWDDIGPLLAKAMGGDEGTYVEAQLLIMERNGFPEETYYTFSYSPIPTDDGSAGGIFCANTDDTQRVISERQLSLLRELASNAAQSRTVAQACESTAKALATDPRDLPFAMIYLMEPGGSSVRLAASAGIDADHPGVKPVLSLVDGAECWPLAEALRFNEPRLLRDLSAQFGFDFPAGGWRQPPSQAIVLPIPSSGDTGQPGFLIAGLNPFRLYDATYRDFFTLVAAQIAAAVTNGDAYEEERRRAEALAEIDRAKTAFFSNVSHEFRTPLTLMLSPLEEVMTQAALPDDQQALLGIAHRNGLRLLKLVNTLLDFARIEAGRVTAQFTPVDLPSFTAELASNFRSAIDKAGLRLIIDAPPLPQPVYVDREMWEKIVLNLLSNAFKFTFAGEIAVTVRAGPDGRSAEIVVSDTGTGIPPTEIPHLFERFRRVEGARGRSIEGSGIGLALVQELVKLHSGSLSVESELGRGSAFRVTLPFGAAHLPAERPQHSALQISTNVRAQVYLDEAMGWLQGEGDAEIDAGRPHASTAEDLGFGASRGGVARPRVLLADDNPDMRDYVARLLGESYEVDAVGDGVAALEAAWKQRPDLVISDIMMPRLDGLSLLKALRNDSTLADVPVIFLSARAGEEARVEGLEAGADDYLSKPFSARELLARVRSNLDIAEVRREALRTEHALRQEAQAARERAEGILASISDGFIALDGDFRFTYVNAAAERLMRRPAAELLGKKYWEVYPAMAGTMIERSYRSAMTDRIGAEFESYHPPSKRWFHLRVSPTNGQSISVYFRDITDRKRAVAALRELNDQLEEQVAERTAELRQKEARLRTIFAASYTYQALLALDGTLIDANLTSLSGIDAKLEDIVGKPLWETPWIVGTPGMSEMIRDAVAAVAAGETVRRELHINLPVGGWRWFDFQMRPVHDAQGQVIAIVPEAVEITERRKAEEAFRQAQKMEAIGQLTGGVAHDFNNLLTVIRSSADLLRRRELPPDRMRRYVDAISDTADRAAKLTGQLLTFARRHAQNRQVFDAAHQIEQIAEMLKTALGSRASFALTVAERPLAVEADANQFDAALVNLVANARDAMDGQGALEIRVARASPTAQETAAGIEGVVAVSIADTGSGIPPDKIDRIFEPFFTTKEIGRGTGLGLSQVYGFAKQSGGNVTVDSEVGAGTTITLRLPLSAKPIEARERTLSGETGKSQERSCVLVVEDNSEVGEFSTQLLHDLGYETVLASSAEQALKLLDQDADRFNIVLSDVVMPGMDGVALGREIRKRLPNLPVVLNSGYAHVLADDGHHGFELLHKPYSVEDLSKVLRRAMTESRRALT GT:EXON 1|1-1427:0| BL:SWS:NREP 4 BL:SWS:REP 77->200|YEGE_ECOLI|5e-04|32.8|122/1105| BL:SWS:REP 360->581,648->761|DHKD_DICDI|2e-37|38.3|336/1546| BL:SWS:REP 795->970|YQIR_BACSU|3e-04|27.7|155/692| BL:SWS:REP 1011->1419|LOVHK_PSE14|3e-63|37.4|401/534| COIL:NAA 41 COIL:NSEG 2 COIL:REGION 773->781| COIL:REGION 895->926| NREPEAT 1 REPEAT 2|94->772|823->1424| SEG 342->359|ayeeerrraealaeidra| SEG 782->793|rqeaqaarerae| SEG 1082->1096|dllrrrelppdrmrr| BL:PDB:NREP 5 BL:PDB:REP 360->581|3dgeA|9e-24|30.2|222/237| BL:PDB:REP 650->765|2zwmA|1e-21|45.1|113/120| BL:PDB:REP 805->894|3fg8E|9e-05|32.2|87/103| BL:PDB:REP 1061->1284|3d36A|2e-23|28.9|211/217| BL:PDB:REP 1307->1423|3jteA|8e-12|28.2|117/126| RP:PDB:NREP 8 RP:PDB:REP 57->184|3caxA|5e-06|11.6|115/355| RP:PDB:REP 174->337|3dbaA|1e-08|9.2|163/171| RP:PDB:REP 360->421|1csgA|2e-08|9.8|61/120| RP:PDB:REP 408->776|1e51A|8e-41|10.1|317/326| RP:PDB:REP 801->906|2cmnA|4e-14|22.6|106/117| RP:PDB:REP 892->952|2btvA|2e-04|6.3|60/845| RP:PDB:REP 987->1293|3d2rB|4e-30|11.9|302/362| RP:PDB:REP 1307->1424|3cu5A|5e-16|20.2|115/124| RP:PFM:NREP 7 RP:PFM:REP 365->424|PF00512|2e-05|40.0|60/69|HisKA| RP:PFM:REP 478->581|PF02518|9e-18|43.1|102/112|HATPase_c| RP:PFM:REP 651->762|PF00072|2e-23|50.0|110/111|Response_reg| RP:PFM:REP 795->893|PF00989|4e-07|34.3|99/112|PAS| RP:PFM:REP 941->1044|PF08448|1e-04|27.9|101/111|PAS_4| RP:PFM:REP 1168->1283|PF02518|2e-16|37.5|105/112|HATPase_c| RP:PFM:REP 1307->1416|PF00072|3e-13|34.8|106/111|Response_reg| HM:PFM:NREP 9 HM:PFM:REP 477->582|PF02518|3.4e-27|37.9|103/111|HATPase_c| HM:PFM:REP 1166->1282|PF02518|9.9e-25|43.4|106/111|HATPase_c| HM:PFM:REP 651->762|PF00072|1.2e-30|44.5|110/112|Response_reg| HM:PFM:REP 1307->1389|PF00072|1.7e-16|39.5|81/112|Response_reg| HM:PFM:REP 67->171|PF08448|3.1e-05|20.0|100/110|PAS_4| HM:PFM:REP 796->898|PF08448|5.1e-19|36.9|103/110|PAS_4| HM:PFM:REP 944->1044|PF08448|6.9e-15|29.8|94/110|PAS_4| HM:PFM:REP 360->425|PF00512|4.1e-16|39.4|66/68|HisKA| HM:PFM:REP 1060->1123|PF00512|4.2e-15|35.9|64/68|HisKA| GO:PFM:NREP 12 GO:PFM GO:0000155|"GO:two-component sensor activity"|PF00512|IPR003661| GO:PFM GO:0007165|"GO:signal transduction"|PF00512|IPR003661| GO:PFM GO:0016020|"GO:membrane"|PF00512|IPR003661| GO:PFM GO:0005524|"GO:ATP binding"|PF02518|IPR003594| GO:PFM GO:0000156|"GO:two-component response regulator activity"|PF00072|IPR001789| GO:PFM GO:0000160|"GO:two-component signal transduction system (phosphorelay)"|PF00072|IPR001789| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF00072|IPR001789| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF00989|IPR013767| GO:PFM GO:0005524|"GO:ATP binding"|PF02518|IPR003594| GO:PFM GO:0000156|"GO:two-component response regulator activity"|PF00072|IPR001789| GO:PFM GO:0000160|"GO:two-component signal transduction system (phosphorelay)"|PF00072|IPR001789| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF00072|IPR001789| RP:SCP:NREP 9 RP:SCP:REP 57->184|2axtC1|2e-05|6.5|126/447|f.55.1.1| RP:SCP:REP 175->339|1mc0A1|3e-08|5.8|155/187|d.110.2.1| RP:SCP:REP 360->426|2c2aA1|3e-12|34.3|67/89|a.30.2.1| RP:SCP:REP 434->582|1b3qA3|1e-29|20.8|149/174|d.122.1.3| RP:SCP:REP 650->766|1a0oA|4e-32|36.8|117/128|c.23.1.1| RP:SCP:REP 801->1056|2axtC1|3e-17|8.5|235/447|f.55.1.1| RP:SCP:REP 1051->1120|1joyA|5e-08|18.6|64/67|a.30.2.1| RP:SCP:REP 1135->1282|1b3qA3|1e-21|18.6|148/174|d.122.1.3| RP:SCP:REP 1307->1419|1a0oA|2e-17|28.6|111/128|c.23.1.1| HM:SCP:REP 64->177|1dp6A_|2.6e-05|19.6|112/0|d.110.3.2|1/3|PYP-like sensor domain (PAS domain)| HM:SCP:REP 210->351|1mc0A2|9e-09|26.0|131/0|d.110.2.1|2/2|GAF domain-like| HM:SCP:REP 341->427|2c2aA1|5.3e-19|39.1|87/0|a.30.2.1|1/2|Homodimeric domain of signal transducing histidine kinase| HM:SCP:REP 414->594|1jm6A2|1.1e-45|38.5|179/190|d.122.1.4|1/2|ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase| HM:SCP:REP 646->799|1s8nA_|1.3e-39|43.7|151/190|c.23.1.1|1/2|CheY-like| HM:SCP:REP 801->906|1dp6A_|1e-18|40.6|106/0|d.110.3.2|2/3|PYP-like sensor domain (PAS domain)| HM:SCP:REP 892->1034|1nwzA_|1.4e-13|33.6|119/0|d.110.3.1|3/4|PYP-like sensor domain (PAS domain)| HM:SCP:REP 1040->1126|2c2aA1|5.7e-14|26.4|87/0|a.30.2.1|2/2|Homodimeric domain of signal transducing histidine kinase| HM:SCP:REP 1120->1288|1gkzA2|3.7e-39|36.1|158/193|d.122.1.4|2/2|ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase| HM:SCP:REP 1302->1419|1s8nA_|1.2e-25|40.0|115/190|c.23.1.1|2/2|CheY-like| OP:NHOMO 28439 OP:NHOMOORG 1008 OP:PATTERN -----------------------5H437-A3I--33-145446GJ-7U8VL6E-2-2-22-------6 W**7Z8BCCCDA79IHIGG-GT88LKGGGGGGVPRRFMPJHPPXPFDBCFEAJLL7AE11KNk9dBPZabC55558779CaHC2699Cqo*k-t453--H9eCMN*U*nx----------11113BA6FA6BILe9*****XFN*8******UcgRT798EEDo*Wq***b7A68778A7867fPF998B8NNWyy*x*z**b*z***wXZROPR***LSRpFWWIFFHFH**CDDDDDDCDDDDDDDEBBA9FAE9HHA897ACCBBIGA9AACAADAJKJCAAC9BBBBBBBBCBBBB899999999B999B67886767DCxad*gggmmpumjhStonKPVMmZc99WNeUB**qfRIBDICGDKD44B*dk*wwnACC9Bee***gRey*s**PPOPOPONONW-********Xwi6tuutrom**znjqwUTfXOegYhgOeSMMMMMMMMLRPIN*ur44444444446B543345555554433334ETjGGNRNHW******tbdeY****jhkmQl***oz**29mwh*evVU*yp*tIco*RWQVpL3344434KKOh**i**wXY*uK**zw*9*******c*******d*J44844444461212111--IQBBVFFjaHvryoFuiXnWfebWbaiffZmiajcux--6LTVZ------VUSVSTKUTTXVWWYSU-TYVSUVVSTVTUVUUUUUSecgMRJIESQQSRTSRQSTQTQSUXRQLRQQUD1TTUVXWUSSXXW--6L88888CCCCMW*Nv656535254455348NMKLOFKFIFkh********x********532415413KXdbkbabbbjlqsu*zzu*vwilnHHEH--*7llMOUV33323323412-------------------------AL8998B8888*7 --1-AC-------1ICEFD99AAB8A85544444444555555555BF99BB8K8B986989231-1--3--321------2222222-362E46244439549AF-94K1-----------------------------------------------9----4-1----1--8-1775U22313p6AYG7I62R2432 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------3- STR:NPRED 1349 STR:RPRED 94.5 SQ:SECSTR ########################################################GcccTTcccccEEEcTTccEEEccGGGGGTTcccTTTGGGccTTcccHccHHHHHHHHHHHTTcccccTTcccccTTcccc#ccccccHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHTTccccccHHHHHHHHHHHHHH#HHHTEEEEEEEEEEEETTEEEEEEEEEEEcTTccHHHHcccGGGccEEcTHHHHHHTccEEEccGGGcTTcccHHHHHHccccccEEEEEEEETTEEEEEEEEEEEcccccccHHHHHHHHHHHHHHHHHTHH####################HHHHHHHHHHHTTTHHHHHHHHHHHTcccHHHHHHHHHHHHHHHHHHHccGGGcccHHHHHHHHHTTccccGGGEEEEEEEEccTTccccccccTTccEEEGGGHHHHHHHHHHTTccEEEEEEEccccccccccTccccccHHHHHHHHHHHHcTTcEEEEEEcccccccccccccccccccHHHHHHHHHHHHHHHHHTTcTTEEEEEEEccccEEEcEEEEccccTTHHHHHHHHHHHTTcTTTcEEccccEEccccTTHHHHHHHccccccccGGGccccccEcTcEEEEEETTEEEEEEccccTTcTHTcccTTcHHHHHHHHHHHHHTTcccEEEEccGGGHHHHHHHHHHcTHHTccEEEEEcHHHHHHHHHHHHTTcccHHHHHHHHHHHHHHHTccEEEETTHHHHHHTccccccccccHHHHHHccccccccHHHHGGGGGccccGGGHHHHHHHHHTcccccccHHHHHHHTcccccHHHHHHHHHHHHHHHHHHHHHHHHHHTTccHHHHTcHHHHHHHHHHHHHHHHHHTTTTccTTcHHHHHHHHHHHHHTTccGGGcccTTcccccEEEcTTccEEEccGGGGGTTTTHcccccccHHHHcHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTccHHHHTcHHHHHHHHHHHHHHHHHHTTccccTTcHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHTTccccHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHTTTcccccEEEEEEEEcccTTcccEEEEcHHHHHHHHHHHHHHHHHHHHHTcccccccccEEEEEEEcccEEccEEEEEEEEccccccHHHHGGGGcTTTTcccHHHccccHHHHHHHHHHHTTcEEEEEEETTTEEEEEEEEEccTTTcccccccccHHHHHTTccTcccccccccccccccccccTTccccGGcHHHHHHHHHHcccccccEEEcccccccccccHHHHHHHHHcHHHHHHHHcccHHHHHHHHHHHHcccTTHHHHHHHHHHHHTccEEEEETTHcH DISOP:02AL 1-4,6-7,386-397,772-791,1422-1428| PSIPRED ccccccccccccccccccccccccccHHHHHHHHccHHHccccccccccHHHHHHHHHHHcccccEEEEEcccEEEEEcHHHHHHHcccHHHHccccHHHHHHHHHHHHHHHHHHHHcccccEEEcccEEEEEccccccEEEEEEEEEEEEcccccEEEEEEEEEccHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHccccccEEEEEEEcccccEEEEEEEcccccccccccccccccccccccHHHHHHHccccEEEcccHHHccccccccccccccEEEEEEEEcccccccEEEEEEEEccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccEEEEEEEccHHHHHHHHHHHHHHHHHHccEEEEEEEcccccEEEEcHHHHHHHHHHHHHHHHHHccccEEEEEEEEEccccEEEEEEEEccccccHHHHHHHccccEEEcccccccccccccHHHHHHHHHHHcccEEEEEEEcccccEEEEEEEccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccEEEEEEccHHHHHHHHHHHHcccEEEEEccHHHHHHHHHcccccEEEEEcccccccHHHHHHHHHHccccccccEEEEEccccHHHHHHHHHccccEEEEccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccHHHHHccccccEEEEcHHHHHHHcccHHHHccccHHHHcHHHHHHHHHHHHHHHHcccEEEEEEEEEcccEEEEEEEEccccccEEEEEEEEcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccEEEEEcccccEEEEcHHHHHHHcccHHHHccccHHHHHHHcccHHHHHHHHHHHHHHHcccccEEEEEEEcccccEEEEEEEEEEEEcccccEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccEEEEHHHHHHHHHHHHHHHHHcccEEEEEEcccccEEEEcHHHHHHHHHHHHHHHHHHcccccEEEEEEEEEcccccccccccccEEEEEEEEccccccHHHHHHHccccEEEcccccccccHHHHHHHHHHHcccEEEEEEEcccccEEEEEEEccccccccccccccccccccccccEEEEEcccHHHHHHHHHHHHHcccEEEEEccHHHHHHHHHHccccccEEEEEcccccccHHHHHHHHHHHcccccEEEEcccHHHHHHHHccccEEEEccccHHHHHHHHHHHHHHcccccc //