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Streptomyces avermitilis MA-4680 (save0)
Gene : BAC68555.1
DDBJ      :             putative modular polyketide synthase
Swiss-Prot:             

Homologs  Archaea  0/68 : Bacteria  806/915 : Eukaryota  161/199 : Viruses  0/175   --->[See Alignment]
a.28.1c.1.19c.19.1c.95.1d.358.1
:1052 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   26->899 2qo3B PDBj 2e-84 32.9 %
:BLT:PDB   883->1006 2vsqA PDBj 7e-16 37.8 %
:RPS:PDB   28->452 2byzA PDBj 1e-58 22.8 %
:RPS:PDB   494->576 3dsgB PDBj 2e-08 10.4 %
:RPS:PDB   549->846 2c2nB PDBj 6e-57 23.9 %
:RPS:PDB   881->1008 3ci0K PDBj 9e-16 7.8 %
:RPS:SCOP  18->518 1e1cA1  c.1.19.1 * 2e-57 9.1 %
:RPS:SCOP  550->809 1nm2A1  c.19.1.1 * 3e-46 19.6 %
:RPS:SCOP  788->901 2hh8A1  d.358.1.1 * 4e-15 10.5 %
:RPS:SCOP  933->1003 1dnyA  a.28.1.2 * 2e-17 35.2 %
:HMM:SCOP  18->397 1tedA_ c.95.1.2 * 7.1e-75 42.3 %
:HMM:SCOP  548->844 1mlaA1 c.19.1.1 * 4.2e-56 44.2 %
:HMM:SCOP  929->1004 1dnyA_ a.28.1.2 * 2.5e-16 40.8 %
:RPS:PFM   28->277 PF00109 * ketoacyl-synt 3e-34 42.6 %
:RPS:PFM   286->393 PF02801 * Ketoacyl-synt_C 3e-17 48.1 %
:RPS:PFM   550->830 PF00698 * Acyl_transf_1 5e-46 48.1 %
:RPS:PFM   942->999 PF00550 * PP-binding 1e-08 46.6 %
:HMM:PFM   27->277 PF00109 * ketoacyl-synt 2.9e-65 40.2 244/253  
:HMM:PFM   551->831 PF00698 * Acyl_transf_1 2.4e-56 36.4 272/318  
:HMM:PFM   285->403 PF02801 * Ketoacyl-synt_C 4.6e-44 53.4 118/119  
:HMM:PFM   939->1001 PF00550 * PP-binding 2.1e-15 34.9 63/67  
:BLT:SWISS 36->915 ERYA1_SACER e-105 35.6 %
:BLT:SWISS 898->1006 LGRB_BREPA 2e-13 31.2 %
:PROS 961->976|PS00012|PHOSPHOPANTETHEINE
:PROS 190->206|PS00606|B_KETOACYL_SYNTHASE
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAC68555.1 GT:GENE BAC68555.1 GT:PRODUCT putative modular polyketide synthase GT:DATABASE GIB00135CH01 GT:ORG save0 GB:ACCESSION GIB00135CH01 GB:LOCATION complement(999163..1002321) GB:FROM 999163 GB:TO 1002321 GB:DIRECTION - GB:PRODUCT putative modular polyketide synthase GB:NOTE nrps7 gene cluster GB:PROTEIN_ID BAC68555.1 LENGTH 1052 SQ:AASEQ MARRHPGSCDSEGRSVTRIPAHEHPDSIAITGMAARLPGAHNVTEYWRNLREGVESIVRHSREEMLANGARRDLVDDPYYVNASAPLEDADRFDAAFFGYAAREASIMEPQHRVFLECAYHALEDAAYDSRRDDALVGVFGGSTMNTYILHNVMPHAEDVVGLVGDLQTMVGNDKDYLTTRVSHKLDLRGPSLAVQTACSTSLVAVHMACRALVDDECDIALAGGASVRMPHAAGYLANPGGTSSPDGHCRAFDADAGGSVVGSGVGVVVLKRLADALRDGDQIHAVIRGSAINNDGQAKASFTAPSVDGQSRAVARALRRAGVDARDIQMVEAHGTGTPLGDPIEVAALTRAFRDWTEDTSYCWLGSAKPNIGHLDAAAGIAGLIKTVLSLKNRKVPPVVNFRRPNPKLALDSSPFRVATELTRLEGDEPLLASVNSLAMGGTNAHVVLEEAPPVRSGGASRRRRHPVLLSAKSGEALEDLSQSLGQWARENPHADVADVAHTLATGRRELPLRRALTAHDLDDVAYGLSTRGSRSQREAQARGSVRTAFLFPGQGTQLPAMGARLAQGDPVFAAHLDRVIGLFQERAGVDLLPVLRPDASTLEEARTTLTATEYTQPALFAVEWALGRTLMDYGVRPYAMLGHSVGELVAATLGGVLDLAPAVELVARRGRLMSETPEGAMLYVNLAEEEAAKLLDDVPGDLTLAAVNADQLVVVSGAPQEVEELAARLRADGVSCGRLEVTRAFHSPLMDTAADTFRQAADSHELHAPQGLVVSNVTGGYLTAQEATDGDYWGRQLRHTVRFNDGLNTLVRDGVSVFIELGPGHTLTRLAAGLGTQAASLTTLAGEGGEEPQDLLDLLTGFWLEGGDVDWSEFYAQEERLRLSLPLYPFARTRHWLDPLPVKTVRTEQAEAAPRAQATPEKPAPRKEIGTTPAQRYVAALWTELLGTDEFGLNDSFFEIGGHSLMAMQMVTRMRKEGAEGLEMTTLFELPTVVGLAEQLERLGVPVPDSGAARTSEDDEETAALLAEVAALSDDEVQARLAELEGDTGA GT:EXON 1|1-1052:0| BL:SWS:NREP 2 BL:SWS:REP 36->915|ERYA1_SACER|e-105|35.6|857/3491| BL:SWS:REP 898->1006|LGRB_BREPA|2e-13|31.2|109/5162| PROS 961->976|PS00012|PHOSPHOPANTETHEINE|PDOC00012| PROS 190->206|PS00606|B_KETOACYL_SYNTHASE|PDOC00529| SEG 258->270|ggsvvgsgvgvvv| SEG 313->328|ravaralrragvdard| SEG 394->409|nrkvppvvnfrrpnpk| SEG 603->617|tleearttltateyt| SEG 1019->1038|eddeetaallaevaalsdde| BL:PDB:NREP 2 BL:PDB:REP 26->899|2qo3B|2e-84|32.9|845/873| BL:PDB:REP 883->1006|2vsqA|7e-16|37.8|119/1273| RP:PDB:NREP 4 RP:PDB:REP 28->452|2byzA|1e-58|22.8|391/405| RP:PDB:REP 494->576|3dsgB|2e-08|10.4|77/95| RP:PDB:REP 549->846|2c2nB|6e-57|23.9|284/308| RP:PDB:REP 881->1008|3ci0K|9e-16|7.8|128/280| RP:PFM:NREP 4 RP:PFM:REP 28->277|PF00109|3e-34|42.6|242/245|ketoacyl-synt| RP:PFM:REP 286->393|PF02801|3e-17|48.1|106/118|Ketoacyl-synt_C| RP:PFM:REP 550->830|PF00698|5e-46|48.1|270/297|Acyl_transf_1| RP:PFM:REP 942->999|PF00550|1e-08|46.6|58/67|PP-binding| HM:PFM:NREP 4 HM:PFM:REP 27->277|PF00109|2.9e-65|40.2|244/253|ketoacyl-synt| HM:PFM:REP 551->831|PF00698|2.4e-56|36.4|272/318|Acyl_transf_1| HM:PFM:REP 285->403|PF02801|4.6e-44|53.4|118/119|Ketoacyl-synt_C| HM:PFM:REP 939->1001|PF00550|2.1e-15|34.9|63/67|PP-binding| GO:PFM:NREP 1 GO:PFM GO:0048037|"GO:cofactor binding"|PF00550|IPR006163| RP:SCP:NREP 4 RP:SCP:REP 18->518|1e1cA1|2e-57|9.1|461/559|c.1.19.1| RP:SCP:REP 550->809|1nm2A1|3e-46|19.6|235/243|c.19.1.1| RP:SCP:REP 788->901|2hh8A1|4e-15|10.5|114/127|d.358.1.1| RP:SCP:REP 933->1003|1dnyA|2e-17|35.2|71/76|a.28.1.2| HM:SCP:REP 18->397|1tedA_|7.1e-75|42.3|338/0|c.95.1.2|1/1|Thiolase-like| HM:SCP:REP 548->844|1mlaA1|4.2e-56|44.2|224/0|c.19.1.1|1/1|FabD/lysophospholipase-like| HM:SCP:REP 929->1004|1dnyA_|2.5e-16|40.8|76/76|a.28.1.2|1/1|ACP-like| OP:NHOMO 4251 OP:NHOMOORG 967 OP:PATTERN -------------------------------------------------------------------- 2241I1211121-1CCDKK-KB99U7LJKKKDE989B3A9-K7J--------333--2--KE--Y3RUCV1--------11111222211121222---115111L2213222222222222221212222212-221133111N369B39AB1111111211211AKDi31111111111111-12222112Z22323422422345222668F2262224212222222L1222222222222222222221--11111-1---11--1-111111111111111241111111111111111111111111111111111221332222322-2-Q2771111213--1222111322112221111111135211122122434262132611122222221221-335352321221555A112221532514153432324532222222214322322112222222211111111111111122221212111221223353DFDDFC4424NNML5L4113232222461161243335324211223122222223321132432211341211113223--B1322-2gP131---1------1-11111111-112332221364-2145333354433334344334--13221------B2C4241333A399433-433333434444433333343584EA32312121222222222333333332-345555444454113234333544534E1312222122222222233443211118A7768EHBC376774C8J322222222333352333333533336554422221212211--------------1-2-------------------------22111111112A1 -152fx2------128CN9UGKLWkUV112554KMD8ABBBAA333MIFQHHFFAAURE878122-11-1111-2-----11121--1-1D3C212------4121--G3S43442-121-22141111171-11211112214-1112-2-142632222218B-7446A4348112D*3-DBG3--1M12111--1P ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 1016 STR:RPRED 96.6 SQ:SECSTR #TTcGGGcccccccHHHHHHHHcccccEEEEEEEEEcTTcccHHHHHHHHHHTcccEEEcHHHHGTTcccccTTcHTTccccEEEccccTTccccTTcHccHHHHTTccHHHHHHHHHHHHHHHHHTccHHTTcTTEEEEEEcccccHHHHHHHHHHHTcccTHHHHcccHHHcTTHHHHHHHTTTTccccEEccccGGGHHHHHHHHHHHHHHTTcccEEEEEEEEcccHHHHHHHHTTTccccGGGTccTTcTTccccccccEEEEEEEEEHHHHHHTTccccEEEEEEEEEEccGccccccccccHHHHHHHHHHHHHTTTccccccEEEccccccHHHHHHHHHHHHHHHTTccGTHHTcEEEcTHHHHcccGGGHHHHHHHHHHHHHHHTEEHTEEccccccccccGGGcccccccccEEcccccccEEEEEEEETTTEEEEEEEEcHHHHHHHHHHHHHTccccccTTTTccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTcTTccccGGGcccHHHccccccHHHHHHHHHHTcEEEEEccTTcccTTTTTTTTTHcTTHHHHHHHHHHHHHHHHcccHHHHHHHccHHHHTcHHHHHEGGGcHHHHHHHHHHHHHHHHHHHHTEEEEEEcTTHHHHHHHHHTcccHHHHHHHHHHHHHHHHHHHHEEEEEEEccTTccHHHHHHHHccEEEEEEEETTEEEEEEEHHHHHHHHHHGGGGTccEEEccccccTTcGGGGGGHHHHHHHHHTccccccccEEEcTTTccccccHTTTHHHHHHHHTTccEEHHHHHHHHHcccccEEEEEccccHHHHHHHHHHTTEEEEcccTccEEEEEccEEEccccEEETTTTcEEEEcccccccccTTccccEEEETTccEEcccEEETTTTEGGcccccHHHHHHHHHHHHTTTccTTcHHHHHcEEcTTccEccGGGcccccccTTcTTcTTccccccccccccEEEEEEccccHHHHHHHHHHHcccccccccccc################################### DISOP:02AL 1-27, 459-460, 1007-1021, 1047-1052| PSIPRED cccccccccccccccccccccccccccEEEEEEEEEccccccHHHHHHHHHccccccccccHHHccccccccccccccccccccEEEccHHcccHHHHcccHHHHHHHcHHHHHHHHHHHHHHHHcccccccccccEEEEEEEcccHHHHHHHHHHHHHccccccccHHHHHHHHHHHHHHHHHHHcccccEEEEHHHHHHHHHHHHHHHHHHHcccccEEEEEcccccccHHHHHHHHHcccccccccccccccccccEEEEcEEEEEEEEcHHHHHHcccEEEEEEEEEEEccccccccccccccHHHHHHHHHHHHHHHcccHHHccEEEccccccccccHHHHHHHHHHHcccccccccEEEEEcHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccccccccccccEEEccccccccccccEEEEEEccccccHHEEEEEccccccccccccccccEEEEEEcccHHHHHHHHHHHHHHHHccccccHHHHHHHHHccccccccEEEEEEccHHHHHHHHHHHccccccccccccccccEEEEcccccccHHHHHHHHHHcHHHHHHHHHHHHHHHHHccccHHHHHccccccccccHHHHccHHHHHHHHHHHHHHHHHHHHHccccEEEEEEccHHHHHHHHHHccccHHHHHHHHHHHHHHHHHcccccEEEEEccHHHHHHHHHcccccEEEEEEEccccEEEEccHHHHHHHHHHHHHcccEEEEEcccccccHHHHHHHHHHHHHHHHccccccccEEEEEccccccccccccccHHHHHHHccccccHHHHHHHHHHccccEEEEccccHHHHHHHHHHccccEEEEEEccccccHHHHHHHHHHHHHHccccccHHHHcccccccccccccccccccccccccccccccccccccccccccccccccccHHHHHHHHHHHHHHHHHHHccccccccccccHHHHHHHHHHHHHHHHHHHHHHcccccHHHHHccccHHHHHHHHHHHccccccccccccccccHHHHHHHHHHHcccHHHHHHHHHHHHHcccc //