[GTOP] [HELP] [ORGANISMS] [SEARCH] [SUMMARY]
Streptomyces avermitilis MA-4680 (save0)
Gene : BAC68838.1
DDBJ      :             putative neutral zinc metalloprotease, secreted
Swiss-Prot:             

Homologs  Archaea  1/68 : Bacteria  160/915 : Eukaryota  14/199 : Viruses  0/175   --->[See Alignment]
d.92.1
:594 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   263->584 1keiA PDBj 3e-41 40.4 %
:RPS:PDB   244->584 1bqbA PDBj 3e-25 32.5 %
:RPS:SCOP  244->584 1bqbA  d.92.1.2 * 3e-64 35.1 %
:HMM:SCOP  239->585 1npcA_ d.92.1.2 * 1.3e-70 40.3 %
:RPS:PFM   68->101 PF07504 * FTP 4e-08 64.7 %
:RPS:PFM   280->399 PF01447 * Peptidase_M4 4e-16 44.9 %
:RPS:PFM   416->584 PF02868 * Peptidase_M4_C 2e-27 50.3 %
:HMM:PFM   416->584 PF02868 * Peptidase_M4_C 4.4e-45 46.4 151/163  
:HMM:PFM   256->398 PF01447 * Peptidase_M4 2.9e-28 41.7 132/151  
:HMM:PFM   63->109 PF07504 * FTP 4.5e-17 44.7 47/51  
:HMM:PFM   125->190 PF03413 * PepSY 8.8e-09 30.0 60/64  
:BLT:SWISS 263->584 THER_BACTH 1e-40 40.4 %
:PROS 387->396|PS00142|ZINC_PROTEASE
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAC68838.1 GT:GENE BAC68838.1 GT:PRODUCT putative neutral zinc metalloprotease, secreted GT:DATABASE GIB00135CH01 GT:ORG save0 GB:ACCESSION GIB00135CH01 GB:LOCATION complement(1415378..1417162) GB:FROM 1415378 GB:TO 1417162 GB:DIRECTION - GB:PRODUCT putative neutral zinc metalloprotease, secreted GB:NOTE PF02868: Thermolysin metallopeptidase, alpha-helical domain GB:PROTEIN_ID BAC68838.1 LENGTH 594 SQ:AASEQ MRRPHIRGVAIAIAVTTAATLPAVPAVADAPALAAAAASSPVDAARAAAFAHASATGVSRGDTLEAKDVLTDPDGKQHVRFVRTHQGLPVLGGDLVVHLTKRSTYLGVTRAADHTVKPAAAGQAKLTPAQAEQKAAAAAQGDATEAALVVDARDGGSALAYQVRVTDSKTTEATGSRTVVVDAVTGRIRSNTPDSDEFISPSLAQTLRERGETANPATGTADSALTGSSLLTGISGAASYPRKASGTGTSLFVGKVGLSTTQTARTSFLLKDSTRWGTETRDAKGQYLEAFSRGKKFTDKNNKWGTGKTSSRQSAAVDAQYGVTKTLDFYKKTFGRKGIKNNSTGARAMVHFGTKVGNAFWDSACGCMLYGDGDGDLFKKPLVVLDVTGHELTHGVVDATAALEPTRVDRDGNQFGEPGSLNESLADIFGTGMEFATNNSKDAGDYLVGEKLGLDQKFLRRLDEPSRDKLEGTIDYWSPETYDTEVHAGSGVSSHAFYLLAEGSGRKTIGGVKYNSPTSDGSTVTGIGRAKALAIFYRALTRYMVSTTDFHDARNATLKAATDMYGADSIEYQTVDKAWAGVNVTSANTPSTGR GT:EXON 1|1-594:0| BL:SWS:NREP 1 BL:SWS:REP 263->584|THER_BACTH|1e-40|40.4|285/548| PROS 387->396|PS00142|ZINC_PROTEASE|PDOC00129| SEG 9->59|vaiaiavttaatlpavpavadapalaaaaasspvdaaraaafahasatgvs| SEG 129->147|aqaeqkaaaaaqgdateaa| BL:PDB:NREP 1 BL:PDB:REP 263->584|1keiA|3e-41|40.4|285/316| RP:PDB:NREP 1 RP:PDB:REP 244->584|1bqbA|3e-25|32.5|292/301| RP:PFM:NREP 3 RP:PFM:REP 68->101|PF07504|4e-08|64.7|34/50|FTP| RP:PFM:REP 280->399|PF01447|4e-16|44.9|118/149|Peptidase_M4| RP:PFM:REP 416->584|PF02868|2e-27|50.3|151/161|Peptidase_M4_C| HM:PFM:NREP 4 HM:PFM:REP 416->584|PF02868|4.4e-45|46.4|151/163|Peptidase_M4_C| HM:PFM:REP 256->398|PF01447|2.9e-28|41.7|132/151|Peptidase_M4| HM:PFM:REP 63->109|PF07504|4.5e-17|44.7|47/51|FTP| HM:PFM:REP 125->190|PF03413|8.8e-09|30.0|60/64|PepSY| GO:PFM:NREP 6 GO:PFM GO:0004222|"GO:metalloendopeptidase activity"|PF07504|IPR011096| GO:PFM GO:0008270|"GO:zinc ion binding"|PF07504|IPR011096| GO:PFM GO:0004222|"GO:metalloendopeptidase activity"|PF01447|IPR013856| GO:PFM GO:0004222|"GO:metalloendopeptidase activity"|PF02868|IPR001570| GO:PFM GO:0005576|"GO:extracellular region"|PF02868|IPR001570| GO:PFM GO:0006508|"GO:proteolysis"|PF02868|IPR001570| RP:SCP:NREP 1 RP:SCP:REP 244->584|1bqbA|3e-64|35.1|288/301|d.92.1.2| HM:SCP:REP 239->585|1npcA_|1.3e-70|40.3|313/0|d.92.1.2|1/1|Metalloproteases ("zincins"), catalytic domain| OP:NHOMO 326 OP:NHOMOORG 175 OP:PATTERN --------------------------------------------------2----------------- ----2---------2-----------------1--------111--1--11-111--1--1-2---1853-------------------------------1----1------------------------------11-----2--1-------------------111-----------------------1445456484555655-----2554-1--111-1111-1-111111111111111-11-11------------------------------------------------------------------------2-6566555-5--------------------------------------------------1-------------------------------------1---------------------------------------------------------------------------11-1111111-111-----1111-11--------------------1--------1------------------------------------------4------------------------------1----------2----1-1111-------2--------------111------------------------------------1111--1--------------1------------------------1-----2333--21----------------------------1111---1-----1111--------------1111121122--21211-32------------23------------------------------------------------- ---------------------1--1-1---------------------211111-----111------------------------------------------------------------------------------------------------------1------------------------1--------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 329 STR:RPRED 55.4 SQ:SECSTR ###################################################################################################################################################################################################################################################EEEEEEcTTccEEEEEEEEEETTEEEcEEccccccEEEEET##EcTTTccEEEcEEcccEEccGGccTTGHHHHHHHHHHHHHHHHHHHHHccccTTcccccEEEEEcccEETTcEEEccccccEEEccccccccccGGGcHHHHHHHHHHHHHHHTTcccccHccc##cccHHHHHHHHHHHHHHHHHHcTTccccccTEEcTTTccTTcTTcccEEcccGGGGTccccGGcccccHHHHHHHHHTHHHHHHHHHHHHcEc#########TcTEETTEEEHHHcHHHHHHHHHHHHHHTccTTccHHHHHHHHHHHHHHHTcHHHHHHHHHHHHHHTTTcc######### DISOP:02AL 1-3, 25-41, 117-123, 586-594| PSIPRED cccccHHHHHHHHHHHHHcccccccHHcccHHHHHHccccHHHHHHHHHHHHHHHHcccccccEEEEEEEEccccEEEEEEEEEEccEEEEccEEEEEEccccEEEEEEEcccccccccccccccccHHHHHHHHHHHHcccccccEEEEEEccccEEEEEEEEEEEEcccccccccEEEEEEccccEEccccccHHHccccccccccccccccccccccccccccccccccccccccccccEEEcccccccccccccEEEEccccEEEEcccccccEEEEEEccccccccccccccccccccccccccccccHHHHHHHHHHHHHHHHHHHHHccccccccccEEEEEEEEccccccEEEcccccEEEEEcccccccccccHHHHHHHHHHHHHHHHHcccccccccccccccccccccccHHHHHHHHHHHHHHHccccccccEEEcHHHcccccEEEEccccccccccccccccccccccccEEEcccHHHHHHHHHHHHcccccccccccccccccccccccHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHccccccHHHHHHHHHHccccccccccccc //