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Streptomyces avermitilis MA-4680 (save0)
Gene : aveBVIII
DDBJ      :aveBVIII     dTDP-4-keto-6-deoxy-L-hexose 2,3-reductase
Swiss-Prot:             

Homologs  Archaea  45/68 : Bacteria  658/915 : Eukaryota  181/199 : Viruses  0/175   --->[See Alignment]
c.1.7
:347 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   30->329 1lqaA PDBj 6e-35 34.1 %
:RPS:PDB   22->332 3eauA PDBj 4e-59 27.1 %
:RPS:SCOP  22->345 1pz1A  c.1.7.1 * 8e-66 29.4 %
:HMM:SCOP  22->337 1pz1A_ c.1.7.1 * 1.4e-81 40.0 %
:RPS:PFM   35->329 PF00248 * Aldo_ket_red 3e-44 40.6 %
:HMM:PFM   34->332 PF00248 * Aldo_ket_red 1.5e-71 34.5 281/284  
:BLT:SWISS 22->345 YRPG_BACSU 8e-78 45.9 %

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAC68662.1 GT:GENE aveBVIII GT:PRODUCT dTDP-4-keto-6-deoxy-L-hexose 2,3-reductase GT:DATABASE GIB00135CH01 GT:ORG save0 GB:ACCESSION GIB00135CH01 GB:LOCATION complement(1210927..1211970) GB:FROM 1210927 GB:TO 1211970 GB:DIRECTION - GB:GENE aveBVIII GB:PRODUCT dTDP-4-keto-6-deoxy-L-hexose 2,3-reductase GB:NOTE avermectin gene cluster GB:PROTEIN_ID BAC68662.1 LENGTH 347 SQ:AASEQ MMPTTAEPAPVQSDSNSSAPLHTELGRTRLRISRLALGTVNIGGRVEEPEARRLMDHALAQGITLFDTANTYGWRVHKGYTEEVIGRWLADRPARREQVVLATKVGDPMGSGPNDHGLSVRNIVAACDASLRRLRTDWIDLYQLHHIDRRAGWDEVWQAMDLLITQGKVRYVGSSNFAGWDIASAQEAARRRNALGLASEQCVYNLVTRHAELEVIPAASAYGVGVLVWSPLHGGLLGGVLRKTRENTAVKSAQGRAVEALEHHRTTIAAYEDVCADHGLDPAHVGMAWVLSRPGVTGLVIGPRTEQHVDGALHALRTPLPEPVLARLEELFPPVGRGGSAPDAWLS GT:EXON 1|1-347:0| BL:SWS:NREP 1 BL:SWS:REP 22->345|YRPG_BACSU|8e-78|45.9|318/326| BL:PDB:NREP 1 BL:PDB:REP 30->329|1lqaA|6e-35|34.1|299/346| RP:PDB:NREP 1 RP:PDB:REP 22->332|3eauA|4e-59|27.1|306/327| RP:PFM:NREP 1 RP:PFM:REP 35->329|PF00248|3e-44|40.6|276/281|Aldo_ket_red| HM:PFM:NREP 1 HM:PFM:REP 34->332|PF00248|1.5e-71|34.5|281/284|Aldo_ket_red| GO:PFM:NREP 2 GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF00248|IPR001395| GO:PFM GO:0055114|"GO:oxidation reduction"|PF00248|IPR001395| RP:SCP:NREP 1 RP:SCP:REP 22->345|1pz1A|8e-66|29.4|313/333|c.1.7.1| HM:SCP:REP 22->337|1pz1A_|1.4e-81|40.0|305/0|c.1.7.1|1/1|NAD(P)-linked oxidoreductase| OP:NHOMO 4141 OP:NHOMOORG 884 OP:PATTERN 222-2-23555544532933313-722718731--------1-21--2-1624-------16433-11 59G3Q-13233-1-14411-1-112A111111133337878F7MFD925EC2BEG328--9863I2GGGF52222143---15--11-4821-3-----1-7132I-424--------------11-1111--12212233111C-434822322111---1-2218A4H4--1---------8731132192533333433233345332554633513424524555535M12222222222222232224217155123226644661361641211111----1111111111111-------------1221--222221-122222222-2-21------4-11-3-2----1---331-23141--2-58332-----B7767--155342-------1--6-45746C478D1-JBB9EGDPMGDC8625-43722236532222222269842133-----------------------------11553424435AAA9AB9545488BA555535E8G2444--22272422434772141-3111-----------122121--2---31----3121-23414787AJ-21-1---------11-1--111--11122271341-6232222222122122112112----111------43571865556566655-54556545655685555559A766---3364645445654556844454541-644444444444----------111-13651-14-5-------1-2221223111B176564657344454877211-12--11-111111111111134767664444111---2111111111-1-----1----1-------------2------2242143444395 --------21--124E9A7CAC8EEIJ4412223213212122211AAELAHMLAB9654442-2-1222365152625635551332-QmH9BZA4458333A87-2DEL7776642333744652D5MX8-B8B142253463141227218453373431941-3228--4228A7d4559DDDJI8BH64RHOGA ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 345 STR:RPRED 99.4 SQ:SECSTR EEEEcccTTHHHHHHHcccccEEEcTTcccEEEcEEEEcTTccccccHHHHHHHHHHHHHTTccEEEEETTGGGGHcHGHHHHHHHHHHHHHTccGGGcEEEEEEcccccccGGGccccHHHHHHHHHHHHHHHTcccEEEEEEccccTTccHHHHHHHHHHHHHTTcEEEEEEEcccHHHHHHHHHHHHHTTcccccEEEEEccTTccHHHHHHHHHHHHHccEEEEEcTTGGGGGGTTTTTcccTTcGGGcTTHHcHHHHHHHHHHHHHHHHHHHHTccHHHHHHHHHHccTTccEEEEccccHHHHHHHHGGGGGGccHHHHHHHHHHHHHHccGGGccccc## DISOP:02AL 1-23| PSIPRED ccccccccccccccccccccccccccccccEEccEEEEEccccccccHHHHHHHHHHHHHccccEEEEcHHcccccccccHHHHHHHHHHHcccccEEEEEEEEEccccccccccccccHHHHHHHHHHHHHHHcccEEEEEEEEcccccccHHHHHHHHHHHHHHccEEEEEEEcccHHHHHHHHHHHHHcccccEEEEEcccccccccHHHHHHHHHHHcccEEEEEcccccccccccccccccccccccccccccHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHcccEEEEEEccccHHHHHHHHHHccccccHHHHHHHHHHHccccccccccHHHHc //