[GTOP] [HELP] [ORGANISMS] [SEARCH] [SUMMARY]
Streptomyces avermitilis MA-4680 (save0)
Gene : aveE
DDBJ      :aveE         cytochrome P450 hydroxylase
Swiss-Prot:             

Homologs  Archaea  8/68 : Bacteria  137/915 : Eukaryota  158/199 : Viruses  0/175   --->[See Alignment]
a.104.1
:456 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   25->396 3el3A PDBj 5e-43 33.8 %
:RPS:PDB   10->444 1e9xA PDBj 2e-35 16.2 %
:RPS:SCOP  10->444 1e9xA  a.104.1.1 * 8e-36 16.2 %
:HMM:SCOP  9->443 1dt6A_ a.104.1.1 * 4.1e-87 30.0 %
:RPS:PFM   30->393 PF00067 * p450 1e-32 29.6 %
:HMM:PFM   10->429 PF00067 * p450 1.8e-63 26.9 416/458  
:BLT:SWISS 9->109 CPXU_RHISN 8e-04 32.7 %
:BLT:SWISS 87->393 CP139_MYCTU 3e-25 28.1 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAC68651.1 GT:GENE aveE GT:PRODUCT cytochrome P450 hydroxylase GT:DATABASE GIB00135CH01 GT:ORG save0 GB:ACCESSION GIB00135CH01 GB:LOCATION complement(1169630..1171000) GB:FROM 1169630 GB:TO 1171000 GB:DIRECTION - GB:GENE aveE GB:PRODUCT cytochrome P450 hydroxylase GB:NOTE CYP171A1, avermectin gene cluster GB:PROTEIN_ID BAC68651.1 LENGTH 456 SQ:AASEQ MMSQSTSSIPEAPGAWPVVGHVPPLMRQPLEFLRSAADHGDLLKLRLGPKTAYLATHPDLVRTMLVSSGSGDFTRSKGAQGASRFIGPILVAVSGETHRRQRRRMQPGFHRQRLESYVATMAAAAQETADSWSAGQVVDVEQAACDLSLAMITKTLFFSDLGAKAEAALRKTGHDILKVARLSALAPTLYEVLPTAGKRSVGRTSATIREAITAYRADGRDHGDLLSTMLRATDAEGASMTDQEVHDEVMGIAVAGIGGPAAITAWIFHELGQNAEIESRLHAELDTVLGGRLPTHEDLPRLPYTQNLVKEALRKYPGWVGSRRTVRPVRLGGHDLPADVEVMYSAYAIQRDPRWYPEPERLDPGRWETKGSSRGVPKGAWVPFALGTYKCIGDNFALLETAVTVAVVASHWRLHALPGDEVRPKTKATHVFPNRLRMIAEPRSVVRLEEPAAMGA GT:EXON 1|1-456:0| BL:SWS:NREP 2 BL:SWS:REP 9->109|CPXU_RHISN|8e-04|32.7|98/447| BL:SWS:REP 87->393|CP139_MYCTU|3e-25|28.1|302/430| SEG 119->129|atmaaaaqeta| SEG 251->267|giavagiggpaaitawi| SEG 397->409|alletavtvavva| BL:PDB:NREP 1 BL:PDB:REP 25->396|3el3A|5e-43|33.8|340/417| RP:PDB:NREP 1 RP:PDB:REP 10->444|1e9xA|2e-35|16.2|433/449| RP:PFM:NREP 1 RP:PFM:REP 30->393|PF00067|1e-32|29.6|358/417|p450| HM:PFM:NREP 1 HM:PFM:REP 10->429|PF00067|1.8e-63|26.9|416/458|p450| GO:PFM:NREP 4 GO:PFM GO:0004497|"GO:monooxygenase activity"|PF00067|IPR001128| GO:PFM GO:0005506|"GO:iron ion binding"|PF00067|IPR001128| GO:PFM GO:0009055|"GO:electron carrier activity"|PF00067|IPR001128| GO:PFM GO:0020037|"GO:heme binding"|PF00067|IPR001128| RP:SCP:NREP 1 RP:SCP:REP 10->444|1e9xA|8e-36|16.2|433/449|a.104.1.1| HM:SCP:REP 9->443|1dt6A_|4.1e-87|30.0|433/460|a.104.1.1|1/1|Cytochrome P450| OP:NHOMO 2643 OP:NHOMOORG 303 OP:PATTERN ------------------------31121121------------------------------------ 21--4---------71244-44--7744544145452334--211---------------211-323512-------------------------------1-1---1----------------------------122-----7-7322441--11------21-13484--------------2------------------------1--1-----------------1---------------------------------------------------------------------------------------------------------------------------------------------------------22112---11211------------23-32312111--112111----12---1-11----111---------12-----------------------------------11-1-------------111111--1111-21----12--------1-1-1-1--------1----------1-------------------------------35-------11111-------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------1------------1--------------------------1-11------------------------------------------------------------------ ----4-2-----44434377467FDC63312224442424244111445635A832533222-11-------1-1------11111---9H74875------1CCJ-21E*JTDSWK8655CI4bS6Y9j*R-ULO374AJ7BKE27796L33TA9BISKLfEKUWAQc**FLb*-E44*74647Uql*4ze32----1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 455 STR:RPRED 99.8 SQ:SECSTR #ccccccccccccccccTTcTHHHHHHcHHHHHHHHHHHccEEEEEETTEEEEEEcHHHHHHHHHHccTTTTTEEcTTccGGGHHHHcccccccccHHHHHHHHHTTTTcHHHHHHHHHHHHHHHHHHHTTcccEEEEEHHHHHHHHHHHHHHHHHTHHTTccHHHHHHHHHHHHcccGGGcTTcccHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccHHHHHHHcccTTccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHGGGccHHHHTTcccHHHHHHHHHHHHHccccccEEEEcccEEETTEEEcTTcEEEEcHHHHTTcTTTcccTTcccGGGGcTTTcHHHHcTTTccTTccGGGccTTHHHHHHHHHHHHHHHHHHEEEEEcccGGGEEccccccEEccccEEEEEEccccccccHHHHHT DISOP:02AL 1-11, 214-223, 236-237, 454-456| PSIPRED ccccccccccccccccccEEcHHHHcccHHHHHHHHHHHccEEEEEEccEEEEEEccHHHHHHHHHHcccHHcccccccHHHHHccccEEEccccHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHccccEEHHHHHHHHHHHHHHHHHHccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHccccccccHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHccccccHHHHHccHHHHHHHHHHHHHccccccccEEEccEEEccEEEccccEEEEcccEEcccHHHcccccccccccccccccccccccEEEEcccccccccHHHHHHHHHHHHHHHHHHHHEEEEccccccccccccEEEEccccEEEEEEEcccccccccccccc //