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Streptomyces avermitilis MA-4680 (save0)
Gene : cyp2
DDBJ      :cyp2         putative cytochrome P450 / NADPH-ferrihemoprotein reductase
Swiss-Prot:             

Homologs  Archaea  9/68 : Bacteria  441/915 : Eukaryota  191/199 : Viruses  1/175   --->[See Alignment]
a.104.1b.43.4c.23.5c.25.1
:1073 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   21->463 2ij2B PDBj e-103 46.7 %
:BLT:PDB   492->1036 3fjoA PDBj 4e-49 27.6 %
:RPS:PDB   15->465 3c6gB PDBj 5e-60 18.7 %
:RPS:PDB   490->1072 2bn4B PDBj 5e-59 22.4 %
:RPS:SCOP  15->463 1dt6A  a.104.1.1 * 2e-55 18.0 %
:RPS:SCOP  492->640 1bvyF  c.23.5.1 * 4e-38 38.5 %
:RPS:SCOP  655->902 1amoA1  b.43.4.1 * 2e-47 23.3 %
:RPS:SCOP  927->1072 1b2rA2  c.25.1.1 * 5e-27 24.3 %
:HMM:SCOP  12->464 1dt6A_ a.104.1.1 * 1.7e-108 32.4 %
:HMM:SCOP  490->649 1tllA2 c.23.5.2 * 2.1e-33 30.4 %
:HMM:SCOP  642->911 1f20A1 b.43.4.1 * 5.3e-55 32.8 %
:HMM:SCOP  913->1072 1f20A2 c.25.1.4 * 2.1e-44 35.8 %
:RPS:PFM   47->434 PF00067 * p450 4e-54 37.5 %
:RPS:PFM   495->616 PF00258 * Flavodoxin_1 2e-13 33.9 %
:RPS:PFM   672->893 PF00667 * FAD_binding_1 2e-29 40.5 %
:RPS:PFM   927->1026 PF00175 * NAD_binding_1 5e-04 34.8 %
:HMM:PFM   14->458 PF00067 * p450 2e-84 30.3 439/458  
:HMM:PFM   711->893 PF00667 * FAD_binding_1 3.5e-41 34.4 180/219  
:HMM:PFM   495->625 PF00258 * Flavodoxin_1 8e-21 33.3 129/143  
:HMM:PFM   926->1036 PF00175 * NAD_binding_1 1.4e-16 34.0 103/109  
:BLT:SWISS 11->1073 CYPD_BACSU 0.0 41.0 %
:PROS 404->413|PS00086|CYTOCHROME_P450
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAC68285.1 GT:GENE cyp2 GT:PRODUCT putative cytochrome P450 / NADPH-ferrihemoprotein reductase GT:DATABASE GIB00135CH01 GT:ORG save0 GB:ACCESSION GIB00135CH01 GB:LOCATION complement(726776..729997) GB:FROM 726776 GB:TO 729997 GB:DIRECTION - GB:GENE cyp2 GB:PRODUCT putative cytochrome P450 / NADPH-ferrihemoprotein reductase GB:NOTE CYP102D1, bifunctional P450:NADPH-P450 reductase GB:PROTEIN_ID BAC68285.1 LENGTH 1073 SQ:AASEQ MTTQPETDLRPIRSPRGVPLFGHTPQIPSTNPVEYFGKLSKQFPEGLYGMEIAGIEQVFVWDPDLVAEVCDETRFFKQIDKTPLAHVRDYAGAGLFTAHQHEEEWGMAHRVLLPVFSQRAMKGYFGQMLEIAQNLVGKWERKEGQPVNITDDYTRLTLDTIALSGFGYRFDSFAKEDLHPFLNALLQALVESLRRSQELPVMTKMRKADDKKYRENIRLMRDLVENVIKERREGKGTGEDDLLGLMLEATDPETGKGLDDDNVRDQVVTFLIAGHETTSGLLSFATYSLMRNPHILAQAYAEVDRLLPGDTVPDYDTIMQMDVIPRILEETLRLWAPIPMIGKSPLEDTVIGGCYGLKKGARVNILEGPLHTHPKAWERPEEFDINRWLPENRVNHHPHAYKPFGNGVRACIGRQFALTEARLALALVLQKFKFADTDDYKMDVKEALTRKPGGFELNVRARQEHERTVFGAADLQTDDTQAQAAVSGVGVNLTVAYGSSLGSCEDLARTIADRGERSGFGTTLVGLDELGDNLPTEGLLVVVASSYNGKAPDNAQRFDDLLAAGLPEGSLSNVRFALLGAGNTQWVATYQGFPKRIEAGLLAAGATRVIERGIADAAGDFDGMATRWMDTLWTTLAEEYAADTSETTGPRFEVQLLTEAEVRPAIVSEQAYPLTVVANEELVSDATGLWDFSIEPPRPAAKSITIELPDGVTYDTGNHLAVFAKNEPVLVNRALARLGVDRDQVLRLDQPGGGRTHLPVGTPVTTGLLFTEFVELQDVATRSQIQELAEHTQCPWTRPQLQAYTADTAEAEERYQKEILGKRVSVLNLLERFPAVELPLAVFLEMMGPIRPRFYSISSSPLANPRHVRLTVGLLEGPALSGDGRYRGTCSSYIAGLESGDVFYGYVRVPSPTFAPPADPATPLLLIGPGTGIAPLRGFLEERAHQHAHGTQVGLSQVFVGCRHPEHDYFYRQEMQDWEQAGIAQVHTAFSAVTGHPARFVQDAIVGAADTVWQAIQDGAYVYVCGDGRRMAPAVREALAAIYRKHTGSDDEAAQQWLAQLEADERYQQDVFA GT:EXON 1|1-1073:0| BL:SWS:NREP 1 BL:SWS:REP 11->1073|CYPD_BACSU|0.0|41.0|1039/1061| PROS 404->413|PS00086|CYTOCHROME_P450|PDOC00081| SEG 910->926|psptfappadpatplll| SEG 1050->1065|ddeaaqqwlaqleade| BL:PDB:NREP 2 BL:PDB:REP 21->463|2ij2B|e-103|46.7|428/448| BL:PDB:REP 492->1036|3fjoA|4e-49|27.6|533/603| RP:PDB:NREP 2 RP:PDB:REP 15->465|3c6gB|5e-60|18.7|449/467| RP:PDB:REP 490->1072|2bn4B|5e-59|22.4|575/641| RP:PFM:NREP 4 RP:PFM:REP 47->434|PF00067|4e-54|37.5|371/417|p450| RP:PFM:REP 495->616|PF00258|2e-13|33.9|121/137|Flavodoxin_1| RP:PFM:REP 672->893|PF00667|2e-29|40.5|205/216|FAD_binding_1| RP:PFM:REP 927->1026|PF00175|5e-04|34.8|92/107|NAD_binding_1| HM:PFM:NREP 4 HM:PFM:REP 14->458|PF00067|2e-84|30.3|439/458|p450| HM:PFM:REP 711->893|PF00667|3.5e-41|34.4|180/219|FAD_binding_1| HM:PFM:REP 495->625|PF00258|8e-21|33.3|129/143|Flavodoxin_1| HM:PFM:REP 926->1036|PF00175|1.4e-16|34.0|103/109|NAD_binding_1| GO:PFM:NREP 10 GO:PFM GO:0004497|"GO:monooxygenase activity"|PF00067|IPR001128| GO:PFM GO:0005506|"GO:iron ion binding"|PF00067|IPR001128| GO:PFM GO:0009055|"GO:electron carrier activity"|PF00067|IPR001128| GO:PFM GO:0020037|"GO:heme binding"|PF00067|IPR001128| GO:PFM GO:0010181|"GO:FMN binding"|PF00258|IPR008254| GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF00258|IPR008254| GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF00667|IPR003097| GO:PFM GO:0055114|"GO:oxidation reduction"|PF00667|IPR003097| GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF00175|IPR001433| GO:PFM GO:0055114|"GO:oxidation reduction"|PF00175|IPR001433| RP:SCP:NREP 4 RP:SCP:REP 15->463|1dt6A|2e-55|18.0|438/449|a.104.1.1| RP:SCP:REP 492->640|1bvyF|4e-38|38.5|148/152|c.23.5.1| RP:SCP:REP 655->902|1amoA1|2e-47|23.3|236/269|b.43.4.1| RP:SCP:REP 927->1072|1b2rA2|5e-27|24.3|140/162|c.25.1.1| HM:SCP:REP 12->464|1dt6A_|1.7e-108|32.4|447/460|a.104.1.1|1/1|Cytochrome P450| HM:SCP:REP 490->649|1tllA2|2.1e-33|30.4|158/0|c.23.5.2|1/1|Flavoproteins| HM:SCP:REP 642->911|1f20A1|5.3e-55|32.8|256/0|b.43.4.1|1/1|Riboflavin synthase domain-like| HM:SCP:REP 913->1072|1f20A2|2.1e-44|35.8|159/0|c.25.1.4|1/1|Ferredoxin reductase-like, C-terminal NADP-linked domain| OP:NHOMO 8471 OP:NHOMOORG 642 OP:PATTERN ------------------------31121121-------------------1---------------- 21--7---111---D7A88-8A11GA888886CEDE888B-2342-------2-------422-626B24-------------------------------1-1-1-1--111111111111111-----------12221---7-A551662--11---1--21-14695--------------1-----115111111111121112126647111-1111--------21-1111111111111111112--------------------------------------------------------------------------------------------------------------------------1111------3484411232443--11-11-111-45455646111-12221111112141--1113----21111111111122---1-------------------------------32311---111111111233322323333-43121224--111-2-212-1-1-----2--1--1211111111------------------------------48-------111111--------------111-112-1-11211111111111111111211--1-1-1--1111222-221111111111-1111111111111111111222231112112121221222222111111111-12222222222211-1---------21-1-111111--------------------1----22-1-1121----2--------1111211111112112412122-213333----11--------------------------------------------------221 1---FO8-H74-78CUYnSeZeeu**iHH9D9BPUKHIEIDIJEDCebbmjjyjHKhLMDDDJ8A4442A5665923133499ADC55-h*mYkpW657646EZaZ-9Bb*p*dx*nQJEJVqU**O*N**s-*k*FLMPvPRqd7QLKBsBG*TgW**hw*Ptpxc****nc**2LE9*DABIS****d**7BWORS8 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- STR:NPRED 1068 STR:RPRED 99.5 SQ:SECSTR #####cccccccccccccTTTcTHHHHHcccHHHHHHHHHHHHcTcEEEEEETTEEEEEEEcHHHHHHHHTTTTTTTcccccccHHHHHHHTTcccTTccTTHHHHHHHHHHHHHHHHTTTTcTTHHHHHHHHHHHHHHHHHTTccccTHHHHHHHHHHHHHHHHHcccccTTcHHHHHHHHHHHHHHHHTTcHHHHHHHHcGGGGGccccHHHHHHHHHHHHHHHHHHHTTTTccTTcccHHHHHHHTTcccTTccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHTcTTcccccGGGGGcHHHHHHHHHHHHHHcccTTcccEEccccEEETTEEEcTTcEEEEEHHHHHTcTTTcccTTcccGGGGccTTccccccccccTTcccTTccTTHHHHHHHHHHHHHHHHHHEEEGGGccccccccccccccccccccEEEEccccEcTEEEccccTTccEEEEEEcTTcTccEEEEEEccccHHHHHHHHHHHHHHHHcccEEEEETTTccTGGGccccEEEEEEccTTcccTTcHHHHHHHHHHccTTTTTTcEEEEEEEEcTTccccTTHHHHHHHHHHHHTTcEEccccEEEETTTTHHHHHHHHHHHHHHHHHHTTccccccccccccccccccccccccccTTccccccccTTcTTccccccccccccccccEEEEEEEEEEcTTcccccTTcEEEEcccccHHHHHHHHHHHTccTTcEEccccccTTTccccccccEEHHHHHHHTccccccccHHHHHTTGGGcccHHHHHHHHHHHTcHHHHHHHTTTTTccHHHHHHHHTTTcccTTccHHHHHHHccccccEEEEcccccTTTTTEEEEEEEccEEccccccccEEcHHHHHHHHHHHHHTTcEEEEEEcccccccccTTccEEEEccGGGGHHHHHHHHHHHHHHHHHHccccccEEEEEccccccTTTTHHHHHHHHTGGEEEEEEEcccTTcccccHHHHHHHcHHHHHHHHTTTcEEEEEEccccHHHHHHHHHHHHHHHHTTccHHHHHHHHHHHHHHccEEEEEcc DISOP:02AL 1-3, 6-10, 230-240, 253-256, 467-491, 1048-1049| PSIPRED ccccccccccccccccccccEEccHHHccccHHHHHHHHHHHccccEEEEEEccccEEEEccHHHHHHHHcccccccccccccHHHHHHHHcccEEEEccccHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHHHHcccEEEHHHHHHHHHHHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHcccccccccHHHHHHHHHHHHHccccHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHcccccccHHHHHccHHHHHHHHHHHHHcccccccccEEEccEEEccEEEEccccEEEEcccccccccccccccccccccccccccccccccEEEEcccccccccHHHHHHHHHHHHHHHHHHHccEEEcccccccccHHHHEEEcccEEEEEEEccccccccccccccccccccccccccccccEEEEEEEccccHHHHHHHHHHHHHHHccccEEEEcHHHHHHHcccccEEEEEEEcccccccHHHHHHHHHHHHcccccccccccEEEEEcccccccHHHHHHHHHHHHHHHHccccEEcccEEEEcccccHHHHHHHHHHHHHHHHHHccccccccccccccEEEccccccccccccccccccEEHHcccccccccccEEEEEccccccEEEEEEEEccccEEccccEEEEcccccHHHHHHHHHHHccccccEEEEEccccccccccccccccHHHHHHHHHHccccccHHHHHHHHHHcccHHHHHHHHHHHccccHHHHHHHHHHHcccccHHHHHHHcccccccHHHHHHHccccccccEEEcccccccccEEEEEEEEEEEEccccccccccEEcHHHcccccccEEEEEEEEccccccccccccccEEEEEccccHHHHHHHHHHHHHHHHcccccccEEEEEcccccccccHHHHHHHHHHHcccEEEEEEEEcccccccEEHHHHHHHHHHHHHHHHHcccEEEEEccccccHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHcccEEEEEcc //