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Streptomyces avermitilis MA-4680 (save0)
Gene : hopA
DDBJ      :hopA         squalene-hopene cyclase
Swiss-Prot:             

Homologs  Archaea  1/68 : Bacteria  144/915 : Eukaryota  167/199 : Viruses  0/175   --->[See Alignment]
a.102.4
:666 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   49->654 1gszA PDBj e-163 49.1 %
:RPS:PDB   52->148 3draB PDBj 2e-05 14.3 %
:RPS:PDB   310->662 3draB PDBj 6e-38 11.5 %
:RPS:SCOP  66->336 1gszA2  a.102.4.2 * 1e-79 44.6 %
:RPS:SCOP  319->654 1gszA1  a.102.4.2 * e-116 52.8 %
:HMM:SCOP  67->333 1w6kA2 a.102.4.2 * 4.5e-75 37.0 %
:HMM:SCOP  326->660 2sqcA1 a.102.4.2 * 4.9e-102 42.8 %
:HMM:PFM   44->64 PF00432 * Prenyltrans 0.00071 47.6 21/44  
:HMM:PFM   95->130 PF00432 * Prenyltrans 9.2e-07 36.1 36/44  
:HMM:PFM   497->537 PF00432 * Prenyltrans 5.2e-08 34.1 41/44  
:HMM:PFM   544->596 PF00432 * Prenyltrans 2.8e-11 42.9 42/44  
:HMM:PFM   604->621 PF00432 * Prenyltrans 5.8e-05 44.4 18/44  
:BLT:SWISS 49->654 SQHC_ALIAC e-162 49.1 %
:REPEAT 4|429->453|496->514|544->564|603->623
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAC69361.1 GT:GENE hopA GT:PRODUCT squalene-hopene cyclase GT:DATABASE GIB00135CH01 GT:ORG save0 GB:ACCESSION GIB00135CH01 GB:LOCATION complement(2020191..2022191) GB:FROM 2020191 GB:TO 2022191 GB:DIRECTION - GB:GENE hopA GB:PRODUCT squalene-hopene cyclase GB:NOTE squalene/hopene gene cluster, shc, PF00432: Prenyltransferase and squalene oxidase repeat GB:PROTEIN_ID BAC69361.1 LENGTH 666 SQ:AASEQ MTATTDGSTGALPPRAASASEPHDTIPQAAGSVGIQDAAARATQRATDFLLSRQDAEGWWKGDLETNVTMDAEDLLLRQFLGIQDEKTTRAAGLFIRGEQRADGTWATFYGGPGDLSATIEAYVALRLAGDGPDEPHMAKASAWIRERGGIASARVFTRIWLALFGWWKWDDLPELPPELIYFPKWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHADANDPNPAKPLAPMVSWDGLFQRLDVALHTYRKVAPRRLRKAAMNTAARWIIERQENDGCWGGIQPPAVYSVIALYLLGYDLEHPVMREGLASLDRFAVWRDDGARMIEACQSPVWDTCLATIALADAGVPADHPQLVRAADWMLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHDPERLDNAIRRGVRWNLGMQSKDGGWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEMLAFEGLSHDPRTRRGIQWLLSAQEANGSWFGRWGVNYVYGTGSVVPALVAAGLPASHPAIRRAVTWLETVQNDDGGWGEDLRSYPEAAEWSGKGASTASQTGWALLALLAAGERESKAVERGIEWLAQTQRPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPLVEVKGG GT:EXON 1|1-666:0| BL:SWS:NREP 1 BL:SWS:REP 49->654|SQHC_ALIAC|e-162|49.1|599/631| NREPEAT 1 REPEAT 4|429->453|496->514|544->564|603->623| SEG 36->48|qdaaaratqratd| SEG 527->541|gsvvpalvaaglpas| SEG 589->596|allallaa| BL:PDB:NREP 1 BL:PDB:REP 49->654|1gszA|e-163|49.1|599/619| RP:PDB:NREP 2 RP:PDB:REP 52->148|3draB|2e-05|14.3|95/364| RP:PDB:REP 310->662|3draB|6e-38|11.5|321/364| HM:PFM:NREP 5 HM:PFM:REP 44->64|PF00432|0.00071|47.6|21/44|Prenyltrans| HM:PFM:REP 95->130|PF00432|9.2e-07|36.1|36/44|Prenyltrans| HM:PFM:REP 497->537|PF00432|5.2e-08|34.1|41/44|Prenyltrans| HM:PFM:REP 544->596|PF00432|2.8e-11|42.9|42/44|Prenyltrans| HM:PFM:REP 604->621|PF00432|5.8e-05|44.4|18/44|Prenyltrans| RP:SCP:NREP 2 RP:SCP:REP 66->336|1gszA2|1e-79|44.6|267/271|a.102.4.2| RP:SCP:REP 319->654|1gszA1|e-116|52.8|335/348|a.102.4.2| HM:SCP:REP 67->333|1w6kA2|4.5e-75|37.0|265/0|a.102.4.2|1/4|Terpenoid cyclases/Protein prenyltransferases| HM:SCP:REP 326->660|2sqcA1|4.9e-102|42.8|334/0|a.102.4.2|2/2|Terpenoid cyclases/Protein prenyltransferases| OP:NHOMO 466 OP:NHOMOORG 312 OP:PATTERN ------------------------------1------------------------------------- 112-1-----------------------------------1212--------------------111111----------------------------------------------------------------------------1111111-----------1111111--------------------1-1111111111111111--1111111--1----------11---------------------------------------------------------------------------------------------------------------------------11-----------------1---------1111111111111------------21111111----------1--------------------22222222111111-1----------------------------------2-----2222222111122111111-12111112--------------------------------111-------------1----121122122--1----2-------------------------11---------------------------------1---------------------------------------------------------------------------------------------------------2-----------------------------1----------------------------------------------------------------------------------------------------------------1-- -1--111-211-1111121365245421122222211212212111111111222222111111111111111111111111111121-22111131111121111-121211111-111-111111114D2-1111111-112--1-1111-311111----11---------1111181111118AG1E411----1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 614 STR:RPRED 92.2 SQ:SECSTR ################################################HHHEEEETTTTEEEEEcccHHHHHHHHHHHHHTTccccccHHHHHHHHHTTccTTccccccTTccccHHHHHHHHHHHHHTTcTccGGGcHHHHHHHHTTTGGGGccHHHHHHHHHTTcccGGGcccccGGGGGccTTcTTcTTcccHHHHHHHHHHHHHHHHcccccccGccGGGTGcccccccccccTcccHHHHHHHHHHHTEEEEcTccccGGGcGGGGGGccccTTcccHHHHHHHHHHHHHHHHHHHHHHHTccccccHHHHHHHHHHHTTHHcccGGGGGGTTcHHHHHHHHHHHHHHTTcccHHHHHHHHHHHHHHHEEcEccccEEEcccHccGGGGGccTTTccccHHHHHHHHHHHHHTTccGGGTHHccHHHHHHHHHHHcccccTTTTccccEEEEETTTTEEEEEcccccHHcHHHHHHHHHHHHHTTccccccHHHHHHHHHTTccTTccccccTTccccHHHHHHHHHHHHHHTTccGGGcHHHHHHHHTTccGTTccccccTTcccHHHHTTTccccTHHHHHHHHHHHHHcGGGGGcHHHHHHHHHHTTccTTTcEEEEccTccccccTTccccHHHHHHHHHHHHHHHHHHHTcc#### DISOP:02AL 1-7, 16-26, 662-666| PSIPRED ccccccccccccccccccccccccccccccccccccHHHHHHHHHHHHHHHHHccccccEEEcccccHHccHHHHHHHHHHccccHHHHHHHHHHHHHHccccccccccccccccHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHcccEEEccHHHHHHHHHHccccccccccccHHHHcccccccccHHHHHHHHHHHHHHHHHHHcccccccccccHHHHHccccccccccccccccHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHcccccccccHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHcEEcccccEEEccccccHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHccccccccHHHHcccccccccccccccccccccccHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHccccccccccccccccHHHHccccHHHHHHcccccccHHHHHHHHHHHccccccHHHHHHHHHHHHHcccccccccccccHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHcccccccccccHHccccccccccccccHHHHHHHHHHHHHHcccccHHHHHHHHHHHHccccccccccccccccccccEEEEccccccHHHHHHHHHHHHHcccccccccc //