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Streptomyces avermitilis MA-4680 (save0)
Gene : ilvB2
DDBJ      :ilvB2        putative acetolactate synthase
Swiss-Prot:             

Homologs  Archaea  54/68 : Bacteria  748/915 : Eukaryota  145/199 : Viruses  0/175   --->[See Alignment]
c.31.1c.36.1
:598 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   32->309 1jscB PDBj 1e-23 27.9 %
:BLT:PDB   451->491 2q29A PDBj 5e-05 39.0 %
:RPS:PDB   26->527 1bfdA PDBj 3e-49 18.4 %
:RPS:SCOP  26->198 1ozfA2  c.36.1.5 * 7e-33 31.5 %
:RPS:SCOP  223->365 1ovmA1  c.31.1.3 * 6e-08 16.8 %
:RPS:SCOP  388->568 1powA3  c.36.1.9 * 2e-11 17.1 %
:HMM:SCOP  11->212 1ybhA2 c.36.1.5 * 4.6e-45 36.9 %
:HMM:SCOP  185->364 1qpbA1 c.31.1.3 * 3.9e-23 30.2 %
:HMM:SCOP  385->578 1ozhA3 c.36.1.9 * 3.5e-36 33.5 %
:RPS:PFM   32->198 PF02776 * TPP_enzyme_N 6e-24 45.6 %
:RPS:PFM   456->496 PF02775 * TPP_enzyme_C 8e-05 43.9 %
:HMM:PFM   25->197 PF02776 * TPP_enzyme_N 3.1e-51 43.7 167/172  
:HMM:PFM   411->557 PF02775 * TPP_enzyme_C 1.4e-26 33.8 142/150  
:HMM:PFM   228->322 PF00205 * TPP_enzyme_M 8.1e-22 29.5 95/137  
:BLT:SWISS 26->198 ILVI_BUCBP 3e-25 34.3 %
:BLT:SWISS 451->491 OXC_ECOLI 2e-04 39.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAC69082.1 GT:GENE ilvB2 GT:PRODUCT putative acetolactate synthase GT:DATABASE GIB00135CH01 GT:ORG save0 GB:ACCESSION GIB00135CH01 GB:LOCATION 1689619..1691415 GB:FROM 1689619 GB:TO 1691415 GB:DIRECTION + GB:GENE ilvB2 GB:PRODUCT putative acetolactate synthase GB:NOTE PF02776: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain GB:PROTEIN_ID BAC69082.1 LENGTH 598 SQ:AASEQ MTTPTSDIRSGIPSDLPEAGTVRLVDHLAGELARAGVTHMFGVGGANIEDLYDAVHRGRAVHGVVAKHEFSAVTMADGYARTTGRLGVVAATSGGGAMNLVPGLAEAYASRVPVLALVGQPPTGQEGHGAFQDSSGRAGSFDAREVFTPVSRFCARVENADSLTELLPRAMAAAQAHPRGPAVLLLPKDVQQARIQVPGRGATPTPGMPEPEPTAEAAWLDSAVLTAVSDTLRGAGRVLVIAGEDVAAADARAELAELAGRLGAWVAVTPDAKDVFDNRDPRFAGVAGVMGHANVEECLRRADVCLLAGTRLPLLARGGLDRALAATEVVCLGPEPPFVAGTALGGNLRDALRAVTGRLPPRPRACPEHAGPLPTPTPSPVSQARGRPIPYAQAVAAVEAALPQDAHVFVDAGNAGASAVHLLPAPRHGRFVVAVGMGGMGYTFGAGIGAALATGRRTYVLAGDGSFFMHGMEVHTAVEYAAPVTFVVFNNNAHAMCAVREEFLQGGVRSDDLFARTDLAAGVAAAFPSLEVTGADDAAQLRQALLRSNAGGGPAFVALDCDPGEIPPFLPFQSFTEATENATENKESPVERGIVHVG GT:EXON 1|1-598:0| BL:SWS:NREP 2 BL:SWS:REP 26->198|ILVI_BUCBP|3e-25|34.3|166/576| BL:SWS:REP 451->491|OXC_ECOLI|2e-04|39.0|41/564| SEG 201->218|gatptpgmpepeptaeaa| SEG 242->264|agedvaaadaraelaelagrlga| SEG 311->326|rlpllarggldralaa| SEG 392->401|aqavaaveaa| SEG 436->450|gmggmgytfgagiga| SEG 535->547|addaaqlrqallr| SEG 576->585|teatenaten| BL:PDB:NREP 2 BL:PDB:REP 32->309|1jscB|1e-23|27.9|269/550| BL:PDB:REP 451->491|2q29A|5e-05|39.0|41/546| RP:PDB:NREP 1 RP:PDB:REP 26->527|1bfdA|3e-49|18.4|479/523| RP:PFM:NREP 2 RP:PFM:REP 32->198|PF02776|6e-24|45.6|160/170|TPP_enzyme_N| RP:PFM:REP 456->496|PF02775|8e-05|43.9|41/139|TPP_enzyme_C| HM:PFM:NREP 3 HM:PFM:REP 25->197|PF02776|3.1e-51|43.7|167/172|TPP_enzyme_N| HM:PFM:REP 411->557|PF02775|1.4e-26|33.8|142/150|TPP_enzyme_C| HM:PFM:REP 228->322|PF00205|8.1e-22|29.5|95/137|TPP_enzyme_M| GO:PFM:NREP 3 GO:PFM GO:0030976|"GO:thiamin pyrophosphate binding"|PF02776|IPR012001| GO:PFM GO:0003824|"GO:catalytic activity"|PF02775|IPR011766| GO:PFM GO:0030976|"GO:thiamin pyrophosphate binding"|PF02775|IPR011766| RP:SCP:NREP 3 RP:SCP:REP 26->198|1ozfA2|7e-33|31.5|165/178|c.36.1.5| RP:SCP:REP 223->365|1ovmA1|6e-08|16.8|143/161|c.31.1.3| RP:SCP:REP 388->568|1powA3|2e-11|17.1|181/228|c.36.1.9| HM:SCP:REP 11->212|1ybhA2|4.6e-45|36.9|195/0|c.36.1.5|1/2|Thiamin diphosphate-binding fold (THDP-binding)| HM:SCP:REP 185->364|1qpbA1|3.9e-23|30.2|159/179|c.31.1.3|1/1|DHS-like NAD/FAD-binding domain| HM:SCP:REP 385->578|1ozhA3|3.5e-36|33.5|188/192|c.36.1.9|1/1|Thiamin diphosphate-binding fold (THDP-binding)| OP:NHOMO 2581 OP:NHOMOORG 947 OP:PATTERN 11-1--2343343442-21221132--211-1243222222221312213443111-----22-1-11 3261741211114255622-2233482222242444528A1224223-222154544211634235866521111111-211311111222111--111-1111131211---------------21111111111211221111522322222211113111222232521111111111111211111-123444443431353435223333333224242-3333332434444444444444423344112133111-2551123333124312111----12211111111111-------------111222111122-34-------3-321331---1-2--2122165222121221112--1-111222-11-1335682125224522232221215-45744838652-2333245553675313147842234563333333322212222-----------------------------1324226B9775778778555577BA77774785D666622553233226245A622321-1211111111112322-722312323333412213112233323342421111111111-1-------11112113222313-2222222422222222322223-1-311111111145442644555465655-5535655545555554554667642256566556666666664854555541-64444443444411-----------32741222212-22212112222221212312888847444588632221----1---312233333322222332222222211111111331122--------------------------------------1--1-111122 --------21----164214332667622222221212122112331136344A-1314222211211-1121211111111111122-23243322222112411--4-2---1----------3121161-111----1-14-----11--11---2121111------111111118111123125122123111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 557 STR:RPRED 93.1 SQ:SECSTR #############ccccTTccEEHHHHHHHHHHHTTccEEEEcccGGGHHHHTTccTTTccEEEEcccHHHHHHHHHHHHHHHTccEEEEEEHHHHHHHTHHHHHHHHHHTccEEEEEEEccHHHHTTTcTTccTEEEEccTGGGTTTTcccEEEccccGGGHHHHHHHHHHHHHccccccEEEEEEGGGTTccccGGGGHHHccccGGTTccccccccccHHHHHHHHHHHHHccccEEEEcHHHHHHTcHHHHHHHHHHHTccEEEcccccccccTTcTTEEEEccHccHHHHHHHHTTccEEEEEccTTccccccccccccTTcEEEEEEccHHccccEEEEccHHHHHHHHHHHcccccccccccccccccccccHccccTcccccHHHHHHHHHHHccTTcEEEEEcGGGHHHHHHHcccccTTcEEEcTTcccccHHHHHHHHHHHcTTccEEEEEEHHHHTTTGGGHHHHHHHTcccEEEEEEccccHHHHHHHHHTTcccccccccccccHHHHHHHHTEEEEEccEccHHHHHHHHHHHHHHTccEEEEEEccTTcccTcc############################ DISOP:02AL 1-22| PSIPRED ccccccccccccccccccccccHHHHHHHHHHHHccccEEEEcccccHHHHHHHHHHccccEEEEEccHHHHHHHHHHHHHHcccEEEEEEcccHHHHHHHHHHHHHHHccccEEEEEcccccHHccccccEEEccccccccHHHHHHHHEEEEEEEccHHHHHHHHHHHHHHHHccccccEEEEEccHHHccccccccccccccccccccccccccccccHHHHHHHHHHHHHccccEEEEccccccHHHHHHHHHHHHHccccEEEccccccccccccccccccccccccHHHHHHHHcccEEEEEccccccccccccccccccccEEEEEccHHHHccccccccHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHccccccccHHHHHHHHHHHcccccEEEEcccHHHHHHHHHHccccccEEEEcccccHHHHHHHHHHHHHHcccccEEEEEEcHHHHccHHHHHHHHHccccEEEEEEEcccccHHHHHHHHHccccccccccccccHHHHHHHHccccEEEEEccHHHHHHHHHHHHHccccEEEEEEccHHHccccccHHHHHHHHHccccccccHHHccccccc //