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Streptomyces avermitilis MA-4680 (save0)
Gene : malS1
DDBJ      :malS1        putative malate dehydrogenase
Swiss-Prot:             

Homologs  Archaea  7/68 : Bacteria  368/915 : Eukaryota  186/199 : Viruses  0/175   --->[See Alignment]
c.2.1c.58.1
:587 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   31->543 1o0sA PDBj 1e-97 38.2 %
:RPS:PDB   35->584 1do8A PDBj 4e-95 33.0 %
:RPS:SCOP  35->293 1do8A2  c.58.1.3 * 8e-86 38.1 %
:RPS:SCOP  293->524 1vl6A1  c.2.1.7 * 4e-30 27.2 %
:HMM:SCOP  1->293 1llqA2 c.58.1.3 * 2e-107 50.9 %
:HMM:SCOP  294->587 1llqA1 c.2.1.7 * 8.8e-90 45.6 %
:RPS:PFM   102->284 PF00390 * malic 1e-49 52.8 %
:RPS:PFM   294->537 PF03949 * Malic_M 9e-59 49.2 %
:HMM:PFM   294->555 PF03949 * Malic_M 1.6e-90 46.9 254/255  
:HMM:PFM   103->284 PF00390 * malic 1.5e-70 57.8 180/182  
:BLT:SWISS 29->587 MAO3_BACSU e-170 57.0 %
:PROS 290->306|PS00331|MALIC_ENZYMES
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAC69224.1 GT:GENE malS1 GT:PRODUCT putative malate dehydrogenase GT:DATABASE GIB00135CH01 GT:ORG save0 GB:ACCESSION GIB00135CH01 GB:LOCATION 1855017..1856780 GB:FROM 1855017 GB:TO 1856780 GB:DIRECTION + GB:GENE malS1 GB:PRODUCT putative malate dehydrogenase GB:NOTE PF03949: Malic enzyme, NAD binding domain putative malate dehydrogenase (oxaloacetate-decarboxylating) GB:PROTEIN_ID BAC69224.1 LENGTH 587 SQ:AASEQ MHPCSPRLVGVPAPDRFGVLMGTQWNAVDGRIRTTARGHAVLNSPRLNRGTAFTRQERQELGLVGLVPPQVLTQDQQAARAYTQFRSQPNDLAKNVYLTALRDRNEVLFHRLLGDHLAEMLPIVYTPTVGTAIERYSYEYRRPRGVYLSVDAPEDIERTLRASGLGADDVDLIVATDGEAILGIGDWGVGGIDIAVGKLAVYTAAAGVDPARTLAVMLDVGTNRQELLDDPLYLGNRHPRVDRESYDAFIDAYVTAATELFPDALLHWEDFGPANARRILDRYREKVRTFNDDIQGTGAVNLAAVLSGVRAGGVPLRDHRVVLFGAGTAGIGIADQLRDALIADGLTPQEATDRIWAVDRHGLLAEDQQGLHDFQLRYVRRGAEIAGWRRDDALGGVPLAEVVDRVRPSVLIGASGQGGAFTEDIVRAMAAHTDRPIILPMSNPTRLAEAVPADLLTWTDGQALIATGSPFDPVEVDGVTHHIGQANNALVFPGLGLGAVVARAERITDGMLVASARAVAEQTDATAPGVPVLPLIDRLRDTSAAVAVAVARAAVEDGVARETVDDAVEERVRAAMWQPEYPPIEAV GT:EXON 1|1-587:0| BL:SWS:NREP 1 BL:SWS:REP 29->587|MAO3_BACSU|e-170|57.0|558/566| PROS 290->306|PS00331|MALIC_ENZYMES|PDOC00294| SEG 61->72|lglvglvppqvl| SEG 180->197|ailgigdwgvggidiavg| SEG 544->560|aavavavaraavedgva| BL:PDB:NREP 1 BL:PDB:REP 31->543|1o0sA|1e-97|38.2|502/602| RP:PDB:NREP 1 RP:PDB:REP 35->584|1do8A|4e-95|33.0|528/539| RP:PFM:NREP 2 RP:PFM:REP 102->284|PF00390|1e-49|52.8|180/180|malic| RP:PFM:REP 294->537|PF03949|9e-59|49.2|236/254|Malic_M| HM:PFM:NREP 2 HM:PFM:REP 294->555|PF03949|1.6e-90|46.9|254/255|Malic_M| HM:PFM:REP 103->284|PF00390|1.5e-70|57.8|180/182|malic| GO:PFM:NREP 3 GO:PFM GO:0016616|"GO:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"|PF00390|IPR012301| GO:PFM GO:0016616|"GO:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"|PF03949|IPR012302| GO:PFM GO:0051287|"GO:NAD or NADH binding"|PF03949|IPR012302| RP:SCP:NREP 2 RP:SCP:REP 35->293|1do8A2|8e-86|38.1|257/259|c.58.1.3| RP:SCP:REP 293->524|1vl6A1|4e-30|27.2|195/222|c.2.1.7| HM:SCP:REP 1->293|1llqA2|2e-107|50.9|293/294|c.58.1.3|1/1|Aminoacid dehydrogenase-like, N-terminal domain| HM:SCP:REP 294->587|1llqA1|8.8e-90|45.6|283/0|c.2.1.7|1/1|NAD(P)-binding Rossmann-fold domains| OP:NHOMO 1070 OP:NHOMOORG 561 OP:PATTERN 11----1--------1---1--------------------------------------1-----1--- 1-1-1-------1----11-1---1-111111------111------1-----1--------121--221--------1------------------------------1------------------------1----12----1------------------1------------------12211-----211111111-111111--2223111-11----111111-1----1--1------------211-22-----2211221112122-11111---11-------------------------1------------2111111-111-----------1-----------------------11--1--1------1111---------1-1--1---1---2--1------------------21--11--1-11---11111111-11-1-------------------------------------1------1111-11112--11111111------------1-----1--1----1-1----------11----111-1------------------------2-----------------------------42-111311221111111111111111111---2-11------31222212212222222-2223222222222222221121221112222222222222222222122221-222222212222--1-1111122221--21---11---111----11111-111--122221111112121222111111111-111311111111121111111111----111---------------1-----------------------------1--11--1-1- --11111-4121--212322222222211111111111111111113222222223222222111111-2111111111111112112-46322373332211545--3434536673333333652626P4-53433335335323332333434443---23314A23711221624j5553547H92632132244 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 554 STR:RPRED 94.4 SQ:SECSTR ##############################ccccccccHTHHHcTTTccGGGccHHHHHHHTcTTTcccccccHHHHHHHHHHHHTTTccHHHHHHHHHHHTTTcHHHHHHHHHHcHHHHHHHHcTTHHHHHHHHHHHHccccccEEEEGGGTTcHHHHHTTcTcccccccEEEEEcccccTTTcccGGGGHHHHHHHHHHHHHHHcccGGGEEEEEEEcccccHHHHTcTTcccccccccccHHHHHHHHHHHHHHHHHcTTcEEEEccccHHHHHHHHHHHTTTccEEEHHHHHHHHHHHHHHHHHHHHHcccGGGccEEEEcccHHHHHHHHHHHHHTTTHTcccHHHHHTTEEEETTEEccTTccccccTTTGGGcccccccccccccccccccHHHHHHHHcccEEEEcccccccccHHHHHHHHHccccEEEEEccccGGGccccHHHHHHHTTTccEEEEccccccEEcTccEEccEEccGGGTHHHHHHHHHHTTcccccHHHHHHHHHHHHTTccHHHHHHcccccGGGHHHHHHHHHHHHHHHHHHTTcccccccccHHHHHHHTccccccccc### DISOP:02AL 1-4| PSIPRED ccccccccccccccEEcccccccccccccccEEEEcccHHHHccccccccccccHHHHHHcccccccccccccHHHHHHHHHHHHHHcccHHHHHHHHHHHHHcccEEEEEEccccHHHHccEEEcccHHHHHHHHHHHHccccEEEEEccccHHHHHHHHHHcccccccEEEEEEcccHHcccccccccccccHHHHHHHHHHHcccccHHcccEEEEccccHHHHHcccHHccccccccccccHHHHHHHHHHHHHHHcccEEEEEHHcccHHHHHHHHHHHccccEEccccccHHHHHHHHHHHHHHHccccccccEEEEEcccHHHHHHHHHHHHHHHHccccHHHcccEEEEEEcccEEEcccccccHHHHHHccccHHHHccccccccccccHHHHHHcccccEEEEcccccccccHHHHHHHHHcccccEEEEcccccccccccHHHHHHHHcccEEEEEccccccEEEcccEEccccEEEEEEHHHHHHHHHHHccEEccHHHHHHHHHHHHHccccccccccccccccHHHHHHHHHHHHHHHHHHHcccccccccHHHHHHHHHHcccccccccccc //