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Streptomyces avermitilis MA-4680 (save0)
Gene : nfi
DDBJ      :nfi          putative endonuclease V
Swiss-Prot:NFI_STRAW    RecName: Full=Endonuclease V;         EC=3.1.21.7;AltName: Full=Deoxyinosine 3'endonuclease;AltName: Full=Deoxyribonuclease V;         Short=DNase V;

Homologs  Archaea  43/68 : Bacteria  183/915 : Eukaryota  75/199 : Viruses  0/175   --->[See Alignment]
:229 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   2->229 3gocA PDBj e-100 100.0 %
:RPS:PDB   107->161 3c65A PDBj 5e-08 20.4 %
:RPS:PFM   80->219 PF04493 * Endonuclease_5 8e-35 53.6 %
:HMM:PFM   21->219 PF04493 * Endonuclease_5 9.8e-67 43.7 199/206  
:BLT:SWISS 1->229 NFI_STRAW e-100 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAC69395.1 GT:GENE nfi GT:PRODUCT putative endonuclease V GT:DATABASE GIB00135CH01 GT:ORG save0 GB:ACCESSION GIB00135CH01 GB:LOCATION complement(2062697..2063386) GB:FROM 2062697 GB:TO 2063386 GB:DIRECTION - GB:GENE nfi GB:PRODUCT putative endonuclease V GB:NOTE PF04493: Endonuclease V GB:PROTEIN_ID BAC69395.1 LENGTH 229 SQ:AASEQ MTTVRIPAGWPATEEEARAVQDELRGRVILDEPGPPPGTGRVTGVDVAYDDERDVVVAAAVVLDAATLDVVAEATAVGEVSFPYVPGLLAFREIPTVLAALDALPCPPGLIVCDGYGVAHPRRFGLASHLGVLTGLPTIGVAKNPFTFSYEDPGAPRGSAAPLLAGADEVGRALRTQSGVKPVFVSVGHRVDLDHACAHTLALTPKYRIPETTRRADSLCRRALKEATA GT:EXON 1|1-229:0| SW:ID NFI_STRAW SW:DE RecName: Full=Endonuclease V; EC=3.1.21.7;AltName: Full=Deoxyinosine 3'endonuclease;AltName: Full=Deoxyribonuclease V; Short=DNase V; SW:GN Name=nfi; OrderedLocusNames=SAV_1684; SW:KW 3D-structure; Complete proteome; Cytoplasm; DNA damage; DNA repair;Endonuclease; Hydrolase; Magnesium; Nuclease. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->229|NFI_STRAW|e-100|100.0|229/229| GO:SWS:NREP 6 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006974|"GO:response to DNA damage stimulus"|DNA damage| GO:SWS GO:0006281|"GO:DNA repair"|DNA repair| GO:SWS GO:0004519|"GO:endonuclease activity"|Endonuclease| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| GO:SWS GO:0004518|"GO:nuclease activity"|Nuclease| SEG 33->77|pgpppgtgrvtgvdvaydderdvvvaaavvldaatldvvaeatav| BL:PDB:NREP 1 BL:PDB:REP 2->229|3gocA|e-100|100.0|228/228| RP:PDB:NREP 1 RP:PDB:REP 107->161|3c65A|5e-08|20.4|54/149| RP:PFM:NREP 1 RP:PFM:REP 80->219|PF04493|8e-35|53.6|140/195|Endonuclease_5| HM:PFM:NREP 1 HM:PFM:REP 21->219|PF04493|9.8e-67|43.7|199/206|Endonuclease_5| GO:PFM:NREP 2 GO:PFM GO:0004519|"GO:endonuclease activity"|PF04493|IPR007581| GO:PFM GO:0006281|"GO:DNA repair"|PF04493|IPR007581| OP:NHOMO 343 OP:NHOMOORG 301 OP:PATTERN 111-1111111111111111111111111111--------------1-1----111111111--1--- ----1-------------------------------1------1----------------21--1111111-----------111111-----------------2-11---------------1-----------1111111111211111-----------1--1111----------------1111---1--------------------11---------------1----------------------------------------------------------------------------------------------12---------------------------1--------------1---------------------------------------1111111----------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------11-----1-11--------------------------------2---------------------------11-1------11111111111111111-1111111111111111111111-11111111111111111111111111111-111111111111-------------1-11--------------------------1---------1----1---------------------------11111111111111----------------------------------------------11111111112-- ----321-211---1-----------------------------------------------------------------------11---------------111-1-221313--1-1-11132121291-2231---2-112-1---1--3111112211211-----1111111-1---1-1111-21--11111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 228 STR:RPRED 99.6 SQ:SECSTR #ccccccTTccccHHHHHHHHHHHGGGcccccccccTTccEEEEEEEEEcccccEEEEEEEEEETTTccEEEEEEEEEEccccccTTcGGGGTHHHHHHHHHTccccccEEEEccccHHHHHHHHHHHHHTccccccEEEccccEETTTTEEccccTTcHHEEEETTEEEEEEEcccTTcccEEEEEEEcccHHHHHHHHHHTcccccccHHHHHHHHHHHHHHHHHHc DISOP:02AL 228-229| PSIPRED cccccccccccccHHHHHHHHHHHHHHcEEccccccccccEEEEEEEEEEccccEEEEEEEEEEccccEEEEEEEEEEEEEccccccHHHHHHHHHHHHHHHHccccccEEEEcccEEEccccccHHHHHHHHHcccEEEEEccEEEEcccccccccccEEEEEEccEEEEEEEEEccccccEEEEccccccHHHHHHHHHHHccccccccHHHHHHHHHHHHHHHHcc //