[GTOP] [HELP] [ORGANISMS] [SEARCH] [SUMMARY]
Streptomyces avermitilis MA-4680 (save0)
Gene : nrps6
DDBJ      :nrps6        putative non-ribosomal peptide synthetase
Swiss-Prot:             

Homologs  Archaea  51/68 : Bacteria  727/915 : Eukaryota  187/199 : Viruses  0/175   --->[See Alignment]
a.28.1c.2.1c.43.1e.23.1
:1440 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   2->1023 2vsqA PDBj 6e-60 24.8 %
:BLT:PDB   1062->1198 2iodD PDBj 5e-04 30.8 %
:RPS:PDB   2->406 2e1vA PDBj 7e-35 9.3 %
:RPS:PDB   458->935 3e7wA PDBj 6e-48 21.4 %
:RPS:PDB   945->1025 2afdA PDBj 3e-12 21.0 %
:RPS:PDB   1063->1358 2b69A PDBj 2e-10 17.7 %
:RPS:SCOP  10->159 1l5aA1  c.43.1.2 * 1e-26 29.0 %
:RPS:SCOP  191->434 1l5aA2  c.43.1.2 * 8e-29 20.7 %
:RPS:SCOP  458->933 1md9A  e.23.1.1 * 8e-48 22.7 %
:RPS:SCOP  954->1023 1dnyA  a.28.1.2 * 2e-17 34.3 %
:RPS:SCOP  1061->1367 1sb8A  c.2.1.2 * 2e-15 17.6 %
:HMM:SCOP  10->201 1l5aA1 c.43.1.2 * 8.7e-37 39.7 %
:HMM:SCOP  190->442 1l5aA2 c.43.1.2 * 3.7e-42 32.4 %
:HMM:SCOP  417->965 1pg4A_ e.23.1.1 * 1.6e-138 35.9 %
:HMM:SCOP  949->1024 1dnyA_ a.28.1.2 * 1.6e-15 36.8 %
:HMM:SCOP  1062->1363 1gy8A_ c.2.1.2 * 1.7e-35 27.3 %
:RPS:PFM   8->299 PF00668 * Condensation 5e-26 35.4 %
:RPS:PFM   502->862 PF00501 * AMP-binding 5e-32 37.8 %
:RPS:PFM   960->1022 PF00550 * PP-binding 4e-07 41.3 %
:RPS:PFM   1066->1300 PF07993 * NAD_binding_4 1e-26 39.2 %
:HMM:PFM   479->869 PF00501 * AMP-binding 9.9e-91 36.4 382/418  
:HMM:PFM   1066->1299 PF07993 * NAD_binding_4 8.5e-61 36.5 233/249  
:HMM:PFM   7->301 PF00668 * Condensation 9.5e-46 27.1 292/301  
:HMM:PFM   959->1022 PF00550 * PP-binding 9e-14 35.9 64/67  
:BLT:SWISS 7->1023 DHBF_BACSU e-172 37.5 %
:BLT:SWISS 1042->1425 HETM_ANASP 6e-42 32.3 %
:PROS 981->996|PS00012|PHOSPHOPANTETHEINE
:PROS 594->605|PS00455|AMP_BINDING
:TM
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAC68313.1 GT:GENE nrps6 GT:PRODUCT putative non-ribosomal peptide synthetase GT:DATABASE GIB00135CH01 GT:ORG save0 GB:ACCESSION GIB00135CH01 GB:LOCATION complement(754376..758698) GB:FROM 754376 GB:TO 758698 GB:DIRECTION - GB:GENE nrps6 GB:PRODUCT putative non-ribosomal peptide synthetase GB:NOTE nrps6 gene cluster GB:PROTEIN_ID BAC68313.1 LENGTH 1440 SQ:AASEQ MDDTARRHPLLAAQEGIWTGQQLDPDSPAYNTAEYVLIEGPVDTAVFDAALHHVVAETEALNVVFVVDDQGRPWQATAPVGDWRLHTADLTTEPNPHAAALAWMGEDMARPVDLARGPVFGHALLRTAPEQYLWYHRVHHIALDGFGLSLVARRVAQVYTALAAGERAAAGGFGTLASVRDEERAYRESPRFAKARAYWADRFADRPPVATPAGRTALPARTFHRRVADLDAAQTQALRAVARDLQLTWSEVLLAVTVAQLHHATRAPEIVLSLPAMGRLGSVSLRVPCMVRNILPLRVAVTASDSLRDLAARISRELRAGLPHQRYRYEQLRRDLKLVGGQRRLSGPGVNIMPFEYDLRFAGHRSTVHNISAGPVDDLSVNVYDRSEGAGLRIAVDANPDLYDEADVAALQEGLLALLEEAVAAPDRALGDLCAREPVPVLDGGPLPGPVRPVLGLIADHAARHGGFVAVEHGGTSITYARLFGSARALARRLAARQVGHGDLVAVALPRGIDAITAILGVLLSGAAYSPLDPTAPRARRAELLDDARPDLVLTTSAFADRFGDRAVLRHDEPGPDSEAAQSTAPTPEDLAYVLHTSGSTGRPKGVEVGHHALAHFVAGATHRYGLHHRDRVLQFAPLHFDTSLEEIFLTLCAGATLVVRTDDMTESVPGFLDACARLRISFLDLPTAYWHELAYAVSTGAVTLPAEVRTVVIGGEAALPERVERWRTAVGTSVRLLNTYGPTEATVVATVADLHDPSLAPGDVPIGLPLPGTRAAVVDGELHLLGDNLAIGYRGDRPPDTSRFAPLDQIPGAPRAYRTGDLVRIGDDGQLRYLGRSDTEFKISGHRVHPAEVEGALLGHPRVRDAVVVGLVLGDGTRRLVAYVVPDGPAPAVALIRDHLRETLPAAMIPSAVEFLDRLPRTSSGKIDRNALAATTPDGHVPEPGAQAATSDSALVRTIAAVWQQVLGVAAVFARDDVFDLGAHSLQAIQVANRLGVELHRDLKVAWLFQHPTPAELARFLEQQEQPRSAPPGLPAALLADTVLDPDIRPGDGPRASGTPDRILLTGATGFVGAHLLAELLTSTGAEAVCTVRAASPAEATARIHQALETHLIHLPDAARERITAVPADLARPRLGVDEALFADLARTCGAIIHNAATVSIMREYATLRAANTESTRDLLRMAAVRSIPLHLVSTLSVAPPLDLAPEVPEAFLAAHPGLRHGYQQSKWAAERLLEQAAERGLPVTVHRLGRIVGPRTTGYVNERDFLWSVLRAGIPARIVPDLFDEETWTPVDHVAQALVHLCLGQRPPGATVFNHATARPVRLADVYDWLEDYGYPLRRMPLAQWRAELPRSSGDSGVAATMLAFFDAWEANPDDATGPELRLGRVRADNVVNGLHGSGITSPPVDRDLVFRYLDHCVTTGTLPAPAGKQSHLATPAK GT:EXON 1|1-1440:0| BL:SWS:NREP 2 BL:SWS:REP 7->1023|DHBF_BACSU|e-172|37.5|994/2378| BL:SWS:REP 1042->1425|HETM_ANASP|6e-42|32.3|378/506| PROS 981->996|PS00012|PHOSPHOPANTETHEINE|PDOC00012| PROS 594->605|PS00455|AMP_BINDING|PDOC00427| TM:NTM 1 TM:REGION 955->977| SEG 161->174|alaageraaaggfg| SEG 409->425|aalqegllalleeavaa| SEG 438->457|pvpvldggplpgpvrpvlgl| SEG 487->497|aralarrlaar| SEG 536->552|aprarraellddarpdl| SEG 863->882|rvrdavvvglvlgdgtrrlv| SEG 1031->1041|appglpaalla| SEG 1230->1241|aaerlleqaaer| BL:PDB:NREP 2 BL:PDB:REP 2->1023|2vsqA|6e-60|24.8|994/1273| BL:PDB:REP 1062->1198|2iodD|5e-04|30.8|120/321| RP:PDB:NREP 4 RP:PDB:REP 2->406|2e1vA|7e-35|9.3|398/434| RP:PDB:REP 458->935|3e7wA|6e-48|21.4|471/508| RP:PDB:REP 945->1025|2afdA|3e-12|21.0|81/88| RP:PDB:REP 1063->1358|2b69A|2e-10|17.7|265/302| RP:PFM:NREP 4 RP:PFM:REP 8->299|PF00668|5e-26|35.4|288/297|Condensation| RP:PFM:REP 502->862|PF00501|5e-32|37.8|341/405|AMP-binding| RP:PFM:REP 960->1022|PF00550|4e-07|41.3|63/67|PP-binding| RP:PFM:REP 1066->1300|PF07993|1e-26|39.2|232/248|NAD_binding_4| HM:PFM:NREP 4 HM:PFM:REP 479->869|PF00501|9.9e-91|36.4|382/418|AMP-binding| HM:PFM:REP 1066->1299|PF07993|8.5e-61|36.5|233/249|NAD_binding_4| HM:PFM:REP 7->301|PF00668|9.5e-46|27.1|292/301|Condensation| HM:PFM:REP 959->1022|PF00550|9e-14|35.9|64/67|PP-binding| GO:PFM:NREP 3 GO:PFM GO:0003824|"GO:catalytic activity"|PF00501|IPR000873| GO:PFM GO:0008152|"GO:metabolic process"|PF00501|IPR000873| GO:PFM GO:0048037|"GO:cofactor binding"|PF00550|IPR006163| RP:SCP:NREP 5 RP:SCP:REP 10->159|1l5aA1|1e-26|29.0|145/174|c.43.1.2| RP:SCP:REP 191->434|1l5aA2|8e-29|20.7|241/250|c.43.1.2| RP:SCP:REP 458->933|1md9A|8e-48|22.7|459/536|e.23.1.1| RP:SCP:REP 954->1023|1dnyA|2e-17|34.3|70/76|a.28.1.2| RP:SCP:REP 1061->1367|1sb8A|2e-15|17.6|290/341|c.2.1.2| HM:SCP:REP 10->201|1l5aA1|8.7e-37|39.7|174/0|c.43.1.2|1/1|CoA-dependent acyltransferases| HM:SCP:REP 190->442|1l5aA2|3.7e-42|32.4|247/0|c.43.1.2|1/1|CoA-dependent acyltransferases| HM:SCP:REP 417->965|1pg4A_|1.6e-138|35.9|541/643|e.23.1.1|1/1|Acetyl-CoA synthetase-like| HM:SCP:REP 949->1024|1dnyA_|1.6e-15|36.8|76/76|a.28.1.2|1/1|ACP-like| HM:SCP:REP 1062->1363|1gy8A_|1.7e-35|27.3|293/383|c.2.1.2|1/1|NAD(P)-binding Rossmann-fold domains| OP:NHOMO 6712 OP:NHOMOORG 965 OP:PATTERN 11-1--37A99AA99611434327522211352111--1111-5546841322----1----21---1 3484U844223737OYMCC-CL55jYCCCCCINOSOTYwy1LCL4--61A7-639477--UPB1gDXVIb7--------135B113213311-1--1---18--1H1212---------------1-111111211777BB111d589D1DDE--1111121-1113JBX3-111---2-11-53354--293M88989E7A98AACE855EEGH88F8EAC732222222R52555655555555554333421112211121132222111111211111112115411111111111111111111-1111111221112----61111511112H277------51-6114-974141--A21111---6235337-111179HFP334ILMFE23332232333-AA9BAE9A7E5-A88D77654885AD35286F567756A11111111421-2A74-----------------------------145L5-6CC7AGKLMNOMGJJDCCDNYZYYCTNAONNSJ-1ECE38E64F79CME2271-21A122222123259552FB14447676555-34414-2444554aH561211-112111-1-------1111511781246513244343392323334232333---2851------94JB543444A4AA543-3454445455455444443657AAQS44243444444434334734355541-476767644565---312131444444S3A111121-111-11117778735445C4JLGKNOGJ5BBCA5GGP1--------13339455555314444645443442222----112211--------1-------------------------------------17- --12763---1-32DJHKDUPaQkjee89BB9ANWPDBCCCFE98AKBIcPQMNHCMIA34331121211112112212221111132-GIAH6B33221427AA6-2A682724474111172H7162JkA-78G341172252234-192-D476392333E952357246841-11V13234856CN79228743A ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 1381 STR:RPRED 95.9 SQ:SECSTR #ccccEEEEccHHHHTTTTccccEEEEEEEEccccHHHHHHTHHHHHHHHHHHHHTTcGGGGcEEEEccccccEEEEEEEEcccGGGTcccccEEGGGGGGcccccccEEccccEEEEcEEEEEEEETTTEEEEEEEEcGGGccHHHHHHHHHHHHHHHHTTcccHHHHEEEHTHHccccccccccccHHHHHHHHHTTcTTHHHHcccccccccccEEEEEEEEcHHHHHHHHHHHHHHcTTcccccHHHHHHHHHHHHHHHHHcccEEEEEEEEEcGcccccTTcccccEEEEEEEEEGGGTcHHHHHHHHHHHHHHHHHHHHHHHHTTcccccHHHHHcccEEEEEccTTTccGGGccccccccEEEEGGGGGccEEEEEEccccTTcEEEEEEEEHHHHHHHHHTTTTccEEEEEEEEEccccccccGGGGcccGGGccEEEEEEEcccEEEEHHHHHHHcTTcEEEEETTEEEEHHHHHHHHHHHHHHTTTccccccccEEEEEcccHHHHHHHHHHHHHTccEEEEETTccHHHHHHHHHHHTccEEEEcccccTTcccccccEHHHTcccccccGGGcccTTcEEEEEEEccTTcccEEEEEEHHHHHHHHHHHHHHcTTTTTcEEEEcccTTcTHHHHHHHHHHHTTcEEEEccHHHHHcHHHHHHHHHHHcccEEEEcHHHHHHHHTcTTccTTTcTTccEEEEccccccccHHHHHHHHHHcTTcEEEEccccGGGccccEEEEEcHHHHTTccccccEEcTTcEEEEEcEEEEEEcTTcccccTTcHHHHHHHEEEEccEEccccEEEEEEEEEEEETTEEEEEEEcccEEEETTEEEEHHHHHHHHHHcTTEEEEEEEEEcccccccEEEEEEEEccHHHHHHHHHHHHHHHccGGGcccEEEEcccccccTTccccHHHHHHEEEETTTTEEEEEEEEcGGGHHHHHcGGGHHHHHHHHHHcEEEEEEEEEEEEHHHHHHHHHHcGGGccEEEEcHHHHHHHHHHHTTTEEcccccc####cccccTTcccE#cccTTccccTTccccEEEEEETTTcHHHHHHHHHHTTTTcEEEEEEccTTcHHHHHHHHTcTTcEEEEEEccccccGGGTGGGTTcTTEEEEEccTTccccccccEEEEccccccHHHHTcHHHHHHHHHHHHHHHHHHHHTcEEEEEEEGGGGcccccccccTTcccccccccTTHHHHHHHHHHHHHHHHHHHcccEEEEEEccEEcTTcTcccHHHHHHHHHHHHTccEEEEcccccEEEcEEHHHHHHHHHHHTHHHHccccccEEEccccEEEHHHHHHHHHHHTccccEEEEcccTTccccccccccHHHHHHTcTTccccccccEEGGGTcTTc##################################################### DISOP:02AL 940-950, 1026-1032, 1354-1357, 1430-1436, 1438-1440| PSIPRED cccccccccccHHHHHHHHHHHHcccccEEEEEEEEEEEccccHHHHHHHHHHHHHHccccEEEEEEEcccEEEEEEcccccccEEEEEcccccHHHHHHHHHHHHHHHccccccccccEEEEEEEEccccEEEEEEccHHHHHHHHHHHHHHHHHHHHHHHHccccccccccccHHHHHHHHHHHHccHHHHHHHHHHHHHHcccccccccccccccccccccEEEEEEcHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHccccEEEEEEEccccHHHHHccccHHHcEEEEEEEEcccccHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHccccccccccEEEEEEEccccccccccccccccccccccccEEEEEEEEccccEEEEEEEEccHHccHHHHHHHHHHHHHHHHHHHHHcccHHHHcccccHHHcccccccccccccHHHHHHHHHHHccccEEEEEccccccHHHHHHHHHHHHHHHHHcccccccEEEEEEcccHHHHHHHHHHHHHccEEEEEcccccHHHHHHHHHHcccEEEEEcHHHHHHccccEEEEEccccccccccccccccccccEEEEEcccccccccEEEEcHHHHHHHHHHHHHHcccccccEEEEEccHHHHHHHHHHHHHHHHccEEEEEcccccccHHHHHHHHHHccccEEEccHHHHHHHHHccccccccccccccEEEEccccccHHHHHHHHHHHccccEEEEccccccHHHEEEEEcccccccccccccccEEccccEEEEEccEEEEccccHHHcccccccccHHHHccccccccccccEEEccEEEEccccEEEEEEccccEEEEccEEEcHHHHHHHHHHcccccEEEEEEEEccccccEEEEEEEEccccccHHHHHHHHHHHccHHccccEEEEEccccccccccccHHHHHHHHHHHHcccccccccccccHHHHHHHHHHHHHHccccccccccHHHHccHHHHHHHHHHHHHHHHcccccHHHHHccccHHHHHHHHHccccccccccccHHHHHHHHcccHHHcccccccccccccEEEEEEcccccHHHHHHHHHHHccHHHHHHHHHHccccHHHHHHHHHHHHHHcccccccccEEEEEcccccccccccHHHHHHHHHHccEEEEcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccEEEEEEEEEcccccccccccHHHHccccccccHHHHHHHHHHHHHHHHHccccEEEEEEccEEEEccccccccHHHHHHHHHHHHHHHccccccccccccEEHHHHHHHHHHHHHccccccccEEEEEccccccHHHHHHHHHHcccccccccHHHHHHHHHHHccccccccHHHHHHHHHHcccccccccHHHHHHHHHHHHHHHHHccccccccccHHHHHHHHHHHHHccccccccccccccccccc //