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Streptomyces avermitilis MA-4680 (save0)
Gene : nrps7-4
DDBJ      :nrps7-4      putative non-ribosomal peptide synthetase
Swiss-Prot:             

Homologs  Archaea  43/68 : Bacteria  661/915 : Eukaryota  170/199 : Viruses  0/175   --->[See Alignment]
a.28.1c.43.1d.129.7e.23.1
:1148 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   68->535 3gqwB PDBj 7e-45 36.1 %
:BLT:PDB   584->1077 2jgpA PDBj 2e-09 22.1 %
:RPS:PDB   15->537 3dhvA PDBj 2e-51 18.5 %
:RPS:PDB   574->625 1dnyA PDBj 6e-06 25.0 %
:RPS:PDB   625->1060 2e1tA PDBj 2e-25 8.1 %
:RPS:PDB   1078->1141 1amuB PDBj 1e-06 12.3 %
:RPS:SCOP  67->539 1ba3A  e.23.1.1 * 2e-43 18.7 %
:RPS:SCOP  574->664 1j3mA  d.129.7.1 * 1e-08 9.9 %
:RPS:SCOP  641->817 1l5aA1  c.43.1.2 * 1e-26 19.7 %
:RPS:SCOP  915->1083 1l5aA2  c.43.1.2 * 8e-16 12.7 %
:RPS:SCOP  1078->1147 1amuA  e.23.1.1 * 5e-07 11.3 %
:HMM:SCOP  14->538 1pg4A_ e.23.1.1 * 5e-119 34.4 %
:HMM:SCOP  551->626 1klpA_ a.28.1.1 * 8.6e-11 31.6 %
:HMM:SCOP  641->814 1l5aA1 c.43.1.2 * 5.8e-31 36.5 %
:HMM:SCOP  818->1083 1l5aA2 c.43.1.2 * 5.9e-31 32.6 %
:HMM:SCOP  1063->1141 1pg4A_ e.23.1.1 * 4.1e-07 26.6 %
:RPS:PFM   67->449 PF00501 * AMP-binding 3e-40 42.4 %
:RPS:PFM   584->619 PF00550 * PP-binding 4e-04 50.0 %
:RPS:PFM   641->849 PF00668 * Condensation 7e-18 38.5 %
:HMM:PFM   46->464 PF00501 * AMP-binding 5.1e-96 36.3 391/418  
:HMM:PFM   640->926 PF00668 * Condensation 4.4e-39 28.2 284/301  
:HMM:PFM   561->623 PF00550 * PP-binding 1.4e-12 41.3 63/67  
:BLT:SWISS 19->535 FAD26_MYCTU 4e-75 41.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAC68557.1 GT:GENE nrps7-4 GT:PRODUCT putative non-ribosomal peptide synthetase GT:DATABASE GIB00135CH01 GT:ORG save0 GB:ACCESSION GIB00135CH01 GB:LOCATION complement(1004016..1007462) GB:FROM 1004016 GB:TO 1007462 GB:DIRECTION - GB:GENE nrps7-4 GB:PRODUCT putative non-ribosomal peptide synthetase GB:NOTE nrps7 gene cluster GB:PROTEIN_ID BAC68557.1 LENGTH 1148 SQ:AASEQ MRETRLTRTSTPLDLVGAIRARAEREGTAVALSWLTDLKDRTDSRTCAELDDAAAAVAAALLAEAAPGDRVLLVQPPGLDFVTSFVGCLYAGCVPVPVYPLLDTAEDRAKVRRIQQDSGSRVTWTSDAGMAEYVADALATPALWRTGEDRYVPSESPAPDTLAFLQYTSGSTAEPRGVMVTHGNLTANLTAIRDAFRHTADSVVLSWLPAYHDMGLIGNILHPLHTGCHAYLASPIDFIRNPTAWPAAVHTYGVTTSGAPDFAYELVARTVDRDGLPAGLDLSGWRTAYSGAEPVSTNTLRRFAEALAPAGFRDDAFVPCYGLAESTLLVTSVPVGAGASTRICREGEEVVTCGVPRDCEVAVGGADGTPLPAGEVGEILVHGPAVAAGYWNRPDLTSEVFAANVSGSDKKWLRTGDLGFLQDGELHVTGRIKDVIIVRGRNHHPQDIERLVVDLCPAVRPGCVAAFAAPDDQGVVIVAELRPGQSLTDDDRARIAGAIATSFGLAPHEIVGVPRGTVPKTTSGKLRRGECRTRYLAGDYADHRFDHGRGPTPGDTAPTAAVRRAVREVLGTGVGDDRPLTLHGLDSLGAVRLTELIARHAGVDIPVRDLLEGATVAGLMERVGTAEPAPVRAGDEASGALSKAQESLLFLHMLAPDSDAYTISFACEPGPGTDHDLFEQALRTALEHQPELHVRFTSSGADGRREPVSTRRMRDALALTPVPVAEDRLAQQLSEAAALPFDPEQGPLLRLYRWQTPTRRVYQVVVHHLVTDLWSLSLVLRDLGSAYSALIAGRPVRLPEPGSYDAYVREQRAYLDSEEAGERDAFLREVLPRRAASLGVRTDFPRTAVRGSRGARVEARVPAPAVPGPAGQDPVSLLAVLWAATLRRYGTPAPVVVGVPVTGRTGGRHGAIGGLCTNTVPLALDVEPDRLLEPLVAAARAQLTAGMDAGLYPLARAVEAVRPDREPGRTPLVETLITYQENPLPDVRGLLEALSGSETELALDTLVLRTVPIERRSCRYDLDLVVTPGPEGLHLTLDYAADLFTERTARAVLDTFCAALAASERTYGARLADLTVLSDHDAALLERIGRCATPPLEPSLLQRVRAVAEHTPGAPAIQGPHQVWSHAEFTRQVERVAHALRLVDDGRS GT:EXON 1|1-1148:0| BL:SWS:NREP 1 BL:SWS:REP 19->535|FAD26_MYCTU|4e-75|41.0|503/583| SEG 48->66|aelddaaaavaaallaeaa| SEG 489->500|dddrariagaia| SEG 560->569|aavrravrev| SEG 853->871|rgarvearvpapavpgpag| SEG 890->914|gtpapvvvgvpvtgrtggrhgaigg| BL:PDB:NREP 2 BL:PDB:REP 68->535|3gqwB|7e-45|36.1|441/542| BL:PDB:REP 584->1077|2jgpA|2e-09|22.1|471/520| RP:PDB:NREP 4 RP:PDB:REP 15->537|3dhvA|2e-51|18.5|487/498| RP:PDB:REP 574->625|1dnyA|6e-06|25.0|52/76| RP:PDB:REP 625->1060|2e1tA|2e-25|8.1|405/440| RP:PDB:REP 1078->1141|1amuB|1e-06|12.3|64/508| RP:PFM:NREP 3 RP:PFM:REP 67->449|PF00501|3e-40|42.4|349/405|AMP-binding| RP:PFM:REP 584->619|PF00550|4e-04|50.0|36/67|PP-binding| RP:PFM:REP 641->849|PF00668|7e-18|38.5|205/297|Condensation| HM:PFM:NREP 3 HM:PFM:REP 46->464|PF00501|5.1e-96|36.3|391/418|AMP-binding| HM:PFM:REP 640->926|PF00668|4.4e-39|28.2|284/301|Condensation| HM:PFM:REP 561->623|PF00550|1.4e-12|41.3|63/67|PP-binding| GO:PFM:NREP 3 GO:PFM GO:0003824|"GO:catalytic activity"|PF00501|IPR000873| GO:PFM GO:0008152|"GO:metabolic process"|PF00501|IPR000873| GO:PFM GO:0048037|"GO:cofactor binding"|PF00550|IPR006163| RP:SCP:NREP 5 RP:SCP:REP 67->539|1ba3A|2e-43|18.7|444/540|e.23.1.1| RP:SCP:REP 574->664|1j3mA|1e-08|9.9|91/127|d.129.7.1| RP:SCP:REP 641->817|1l5aA1|1e-26|19.7|173/174|c.43.1.2| RP:SCP:REP 915->1083|1l5aA2|8e-16|12.7|150/250|c.43.1.2| RP:SCP:REP 1078->1147|1amuA|5e-07|11.3|70/510|e.23.1.1| HM:SCP:REP 14->538|1pg4A_|5e-119|34.4|500/643|e.23.1.1|1/2|Acetyl-CoA synthetase-like| HM:SCP:REP 551->626|1klpA_|8.6e-11|31.6|76/115|a.28.1.1|1/1|ACP-like| HM:SCP:REP 641->814|1l5aA1|5.8e-31|36.5|170/0|c.43.1.2|1/1|CoA-dependent acyltransferases| HM:SCP:REP 818->1083|1l5aA2|5.9e-31|32.6|242/0|c.43.1.2|1/1|CoA-dependent acyltransferases| HM:SCP:REP 1063->1141|1pg4A_|4.1e-07|26.6|79/643|e.23.1.1|2/2|Acetyl-CoA synthetase-like| OP:NHOMO 5409 OP:NHOMOORG 874 OP:PATTERN 11----1232323332--31232732221132211---1111132535-1111--------------- -234P442443627QbPNN-NP88fZNNNNNJRUZUOh*w1UBP2--2124-444335--LJ61XENMER53122122-2329123113311-2111--113--1D-21----------111111-1--2--11-188898111T38EA1AAA1111-1-1-13-16B7Q4--1--1-1----32243--176J88888B789899AB734BB8F78E4B9C622111121P3-222222222222222---11-1-11-------11-----2-1------1----11-------------------------11---111-1---21111211---9-44------5--5113-861142--731111---3-45779-----55GEQ225KFIFD11111111112-67D88D79896-777B45354753AC26486A335495B1111111152123464------------------------------8ALB12BA59ADEFHIIDEE999AJNOON9LK7OMSWK1288A47896I57EII116----8122112221235232TC54223233333-5673432456756XF25-1-1-1111-1----------1112--14-314312325333366344434333356--1152-------22B42223335355443-244444333333343344343444BC1323334344432323352335542--245435522233---133342344343M26111111-111-1111444441334495ACBCKGED6A9A96CBJ111111111-1226111113212222222232221111----------111-11--2--------------------------------------5- --2254------335BEEANEGEIQLOBC8969AF899586899BA87AGDBGGA8CA89574--1--1-1----1111-1-----2--666E6654311116768-3M4E7C9H763123252771618R43455221362351144-2C-132563B6585D4C68468576D11-3N22172BA9NKBC2255445 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 1143 STR:RPRED 99.6 SQ:SECSTR ####HTTccHHcccHHHHHHHHHHHcTTcEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHcTTccccEEEEEcccHHHHHHHHHHHHTTccEEEEETTccHHHHHHHHHHHHHHHTccEEEEcccccccccccEEEETHHHHHHHHHTTTccccGGGcccTTcEEEEEEEccEEEEEEHHHHHHHHHHHHHHTTcccccEEEEcccTTcGGGHHHHHHHHHTTcEEEEccHcHHHHHcHHHHHHHHHHHTccEEEEcHHHHHHHHTcTTccccTcTTTcTTccEEEEccccccHHHHHHHHHHHTccccTTcEEEEEEccGGGccccEEEEccHHHHccccccEEEcTTcEEEEEccEEEEcTccccccTTccEEEEEEcTTcccccTTcHHHHHHHEEEETEETTEEEEEEEEEEEEETTEEEEEEEGGGEEEccccEEEHHHHHHHHHHccTTEEEEEEEEEEcccEEEEEEEEEEcccccccHHHHHHHHHHHHTTccGGGcccEEEEcccccccTTccccHHHHHHHHHcHccTTTcTTTHHHHHHHHHHHHHHHcTTTEEEHHHHTTTcccTTcEEEEEEHHHHHHHHHHcGGGccEEEEcHHHHHHHHHTTEEEcEEEcccTTTcccEEEEccHHHHcTTTTcccEEEEEEEEccccHHHHHHTHHHHHHHHHHHHHHHcGGGGcEEEEcccccccEEEEcccGGGTcccccEEGGGcGGGcccccccEEccccEEEEcEEEEEEEETTTEEEEEEEcGGGccHHHHHHHHHHHHHHHHTTcccHHHHHHHHHHHccccccccccccHHHHHHHHHHHcHHHHHHHcccccccccccEEEEEEEEcHHHHHHHHHHHHHHcTTcHHHHHHHHHHHHHHHHHcccEEEEEEEEEcGGGccccccTTcccccEEEEEEEEEGHHHHHHHHHHHHHHHHHHHTTcccccHHHHHccccEEEEEEccTcTTTcEETccGGGccccccGccTTcGccTcccccccccEEEEGGGGGccEEEEEEcccccEccEEEEEEEEHHHHHHHHHHHHHHHcTTHHHHTTccccccccccHHHHHHTccTTcTTccHHHHHHHTTTTTTcccccHHHHHHHHHHHHHTTcccHHHHHHHTTcHHHTccT# DISOP:02AL 3-4, 1147-1148| PSIPRED ccccccccccccccHHHHHHHHHHHccccEEEEEEccccccccEEcHHHHHHHHHHHHHHHHHccccccEEEEEEcccHHHHHHHHHHHHHccEEEEcccccccccHHHHHHHHHHccccEEEEEccHHHHHHHcccccccccccccccccccccccccccEEEEEEcccccccccEEEEcHHHHHHHHHHHHHHcccccccEEEEEcHHHHHHHHHHHHHHHHHHccEEEEEccHHHHccHHHHHHHHHHccccEEEccHHHHHHHHHHHccccccccccccccEEEEEccccccHHHHHHHHHHHccccccccEEEEccccHHHHHcEEEEccccccccccccccccccccccccccEEEEEcccccccccccEEEEEEccccccccccccHHHHHHHHccccccccccEEEEccEEEccccEEEEEEccccEEEEccEEEcHHHHHHHHHHccccHHcEEEEEEEcccccEEEEEEEEcccccccHHHHHHHHHHHHHHcccccEEEEEEEcccccccccccccHHHHHHHHcccccHHHccccccccccHHHHHHHHHHHHHHHcccccccccccHHHHcccHHHHHHHHHHHHHHHcccccHHHHHccccHHHHHHHHHHHccccccccccccccccccccccEEEEEEcccccEEEEEEEEEEcccccHHHHHHHHHHHHHHccccEEEEEEEcccEEEEEEcccccccEEEEEEccccHHHHHHHHHHHHHccccccccccEEEEEEEEcccEEEEEEEHHHHHcHHHHHHHHHHHHHHHHHHHccccccccccccHHHHHHHHHHHcccHHHHHHHHHHHHHHccccccccccccccccccccccccEEEEEccHHHHHHHHcccHHHHHHHHHHHHHHHHHcccEEEEEcccccccHHHHHHHHHHHHcEEEEEEEEcccccHHHHHHHHHHHHHHHHHHccccHHHHHHHHccccccccccHHHHHHHHcccccHHHHHHHHHcccccccccccccEEEEEEcccccccccEEEEEEEcccEEEEEEEEccccccHHHHHHHHHHHHHHHHHHHHcccccccccccccHHHHHHHHHcccccccccccHHHHHHHHHHHHccccEEEEEcccEEcHHHHHHHHHHHHHHHHHcccccc //