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Streptomyces avermitilis MA-4680 (save0)
Gene : nrps8
DDBJ      :nrps8        putative non-ribosomal peptide synthetase
Swiss-Prot:             

Homologs  Archaea  31/68 : Bacteria  588/915 : Eukaryota  162/199 : Viruses  0/175   --->[See Alignment]
e.23.1
:515 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   74->511 3e7wA PDBj 3e-35 29.5 %
:RPS:PDB   7->511 3dhvA PDBj 2e-50 21.0 %
:RPS:SCOP  4->507 1md9A  e.23.1.1 * 6e-45 19.2 %
:HMM:SCOP  6->511 1pg4A_ e.23.1.1 * 1.8e-123 39.1 %
:RPS:PFM   56->443 PF00501 * AMP-binding 2e-24 31.8 %
:HMM:PFM   33->445 PF00501 * AMP-binding 3.5e-88 33.8 394/418  
:BLT:SWISS 55->507 GRSB_ANEMI 2e-45 35.1 %
:PROS 158->169|PS00455|AMP_BINDING
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAC68960.1 GT:GENE nrps8 GT:PRODUCT putative non-ribosomal peptide synthetase GT:DATABASE GIB00135CH01 GT:ORG save0 GB:ACCESSION GIB00135CH01 GB:LOCATION 1551427..1552974 GB:FROM 1551427 GB:TO 1552974 GB:DIRECTION + GB:GENE nrps8 GB:PRODUCT putative non-ribosomal peptide synthetase GB:NOTE nrps8 gene cluster, PF00501: AMP-binding enzyme GB:PROTEIN_ID BAC68960.1 LENGTH 515 SQ:AASEQ MSDPQNLYAWFARSAAAYGDECTALEIGDDRLSYGALRDLAERLAGRLVAAAGGTPPRRVGLLASRSVTAYAGYLAVLRAGATVVPLNPEHPSARTRDIVEAAGLELVLADAPAAGADLGVPVLVAGPEELAALAALVDEPVPELPDARTGPDDIAYIIFTSGSTGAPKGVPILHRNICAYLGQVAPRYDIEPGSRLSQSFELTFDGSVHDLFVAWAGGGTLVVPMRSQLLSPVKTINSLRLTHWFSVPSLISFASRLGTLEPGSLPTLRWSIFGGEPLTLAAAREWRAAAPDSRLEVLYGPTELTISCTAYRFPDDLADWPKTPNGTAPIGTCYPFLDLLLLDADDRPSDSGELYVRGPLRFPGYLDPANNAGRFLTSAQHPATEEPLTDRHWYRTGDRVAMRDGHLVHLGRTDHQVKIRGHRIELGEIEAMLRQQPGVRDAIVLAVPASDGEPELEAAVSGTGCVPDRLYSALGDRLPPYMLPRRIAVLDQLPLNPNGKIDRRALLAELGRSR GT:EXON 1|1-515:0| BL:SWS:NREP 1 BL:SWS:REP 55->507|GRSB_ANEMI|2e-45|35.1|430/4451| PROS 158->169|PS00455|AMP_BINDING|PDOC00427| SEG 40->54|laerlagrlvaaagg| SEG 107->143|lvladapaagadlgvpvlvagpeelaalaalvdepvp| SEG 282->291|aaarewraaa| SEG 338->347|ldlllldadd| BL:PDB:NREP 1 BL:PDB:REP 74->511|3e7wA|3e-35|29.5|413/508| RP:PDB:NREP 1 RP:PDB:REP 7->511|3dhvA|2e-50|21.0|485/498| RP:PFM:NREP 1 RP:PFM:REP 56->443|PF00501|2e-24|31.8|368/405|AMP-binding| HM:PFM:NREP 1 HM:PFM:REP 33->445|PF00501|3.5e-88|33.8|394/418|AMP-binding| GO:PFM:NREP 2 GO:PFM GO:0003824|"GO:catalytic activity"|PF00501|IPR000873| GO:PFM GO:0008152|"GO:metabolic process"|PF00501|IPR000873| RP:SCP:NREP 1 RP:SCP:REP 4->507|1md9A|6e-45|19.2|485/536|e.23.1.1| HM:SCP:REP 6->511|1pg4A_|1.8e-123|39.1|486/643|e.23.1.1|1/1|Acetyl-CoA synthetase-like| OP:NHOMO 4217 OP:NHOMOORG 781 OP:PATTERN ------222222211---1121--1--211--------21111221231-312--------------- 2-22M633223726IJEBB-BC22PPBBBBB7HGFGKSmd1I7G2--2152-435327--MI31UBNMET3--------1331-----22-----------8--1G---2-------------------1-----132285---T257B-BBC-------------2F9Q1-------1----121----123L22323725525468331999F22946681-1111111N1122222222222222122111111111112113111111111-11111111211541111111111111111111111111111221112----41111511112E266------41-1111-572-21---1---1---4121114-----4894H-11ABC75-1----1--12-553657573B2-66681122233129-2143C2233648--------31--1323------------1----1--1-11------35D5-278557BCCDFHCFFA5557RRRQ9KB6CDAGH--32625722D225F8--3----6--------114423-8521123341----4343313222112UE241--1-111111-------------2--45---41-----111-7------------1---1531------A1G73111227188311-212111313323311111121478MQ1211222222122222251111111--265656433353---213121323224L-8111------------6666612---94CFCDMDDB297982EEK122222222--118122224--222243233-------------------------1--------------------------------------8- ----111-42--559GIJBSLWOYaVaBCEECDLNJFABABBAA88D9CWOOGKE9JF8445611211-11-1-1-1-1121111123-7B4I6821111316623-25291125212--1-2-33-1-7K3--58----11-1-1-1--3--2142271133C54524332483----D31231B64KM8B2235218 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 511 STR:RPRED 99.2 SQ:SECSTR HHccccHHHHHHHHHHHcTTccEEEEETTEEEEHHHHHHHHHHHHHHHHHHcTTcccccEEEEEcccHHHHHHHHHHHHTTccEEEEETTccHHHHHHHHHHHTccEEEEcccccccccccEEEETHHHHHHHHHTTcHHHHTccTccccGGGcccTTcEEEEEEEccEEEEEEHHHHHHHHHHHHHHTTcccccEEEEcccTTcGGGHHHHHHHHHTTcEEEEccHHHHHcHHHHHHHHTccEEEEcHHHHHHHHTcTTccTTTcTTccEEEEccccccHHHHHHHHHHcTTcEEEEEEccGGGccccEEEEEccHHHHHHccccccEEEcTTcEEEEEccccccccTTccEEEEEEcTTcccccTTcHTcHHHHHHHEEEETHHHHEETEEEEEEEEEEEEETTEEEEEEEGGGEEEccccEEEHHHHHHHHHHcTTEEEEEEEEEEccccEEEEEEEEccHHHHHHHHHHHHHTTccGGGcccEEEEcccccccTTccccHHHHHHHH#### DISOP:02AL 511-515| PSIPRED ccccccHHHHHHHHHHHcccccEEEEEcccEEcHHHHHHHHHHHHHHHHHHcccccccEEEEEEcccHHHHHHHHHHHHHccEEEEccccccHHHHHHHHHHcccEEEEEcHHHHHHcccccEEEEcccccccHHHHHccccccccccccccccEEEEEEccccccccccEEEcHHHHHHHHHHHHHHcccccccEEEEEccHHHHHHHHHHHHHHHHccEEEEcccccHHHHHHHHHHccccEEEEcHHHHHHHHHccccccccccccEEEEEEcccccHHHHHHHHHHccccEEEEccccccHHHcEEEEEcccccccccccccccccccccccccEEEEEccccccccccEEEEccccEEccccccHHHHHHHHcccccccccccccccccEEEccEEEEcccEEEEEEccccEEEEccEEEcHHHHHHHHHHccccEEEEEEEEEccccccEEEEEEccccccHHHHHHHHHHHccHHccccEEEEccccccccccHHHHHHHHHHHHHcc //