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Streptomyces avermitilis MA-4680 (save0)
Gene : orf-1
DDBJ      :orf-1        reductase
Swiss-Prot:             

Homologs  Archaea  45/68 : Bacteria  833/915 : Eukaryota  186/199 : Viruses  0/175   --->[See Alignment]
c.2.1
:237 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   30->211 2cfcA PDBj 2e-19 37.0 %
:RPS:PDB   26->165 3ce6B PDBj 6e-28 10.1 %
:RPS:SCOP  2->197 1pwxA  c.2.1.2 * 3e-26 20.2 %
:HMM:SCOP  2->208 1zemA1 c.2.1.2 * 1.3e-47 34.6 %
:RPS:PFM   31->141 PF00106 * adh_short 4e-10 41.8 %
:HMM:PFM   10->142 PF00106 * adh_short 9.8e-25 27.8 126/167  
:BLT:SWISS 25->233 EPHD_MYCTU 1e-41 42.8 %
:PROS 111->139|PS00061|ADH_SHORT

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAC68654.1 GT:GENE orf-1 GT:PRODUCT reductase GT:DATABASE GIB00135CH01 GT:ORG save0 GB:ACCESSION GIB00135CH01 GB:LOCATION 1202833..1203546 GB:FROM 1202833 GB:TO 1203546 GB:DIRECTION + GB:GENE orf-1 GB:PRODUCT reductase GB:NOTE not involved in biosynthesis of avermectin, PF00106: short chain dehydrogenase GB:PROTEIN_ID BAC68654.1 LENGTH 237 SQ:AASEQ MCVDRDGRGAGVTADLARTRGARAAWPEVADVSDGAAMERFAERVAETYGVVDLLVNNAGIGMAGRFLDTSVEDWQRTLGVNLWGVIHGCRLIGRQMAERGQGGHIVTVASAAAFQPTRAVPAYATSKAAVLMLSECLRAEFAEFGVGVSVVCPGFVRTSFASAMHFAGVPRLEQERLRALFAGRGCSAEKVAAAVLRSVARDSAVVTVTAEARLSRLMSRFTPRLRAAVARMDPPS GT:EXON 1|1-237:0| BL:SWS:NREP 1 BL:SWS:REP 25->233|EPHD_MYCTU|1e-41|42.8|208/592| PROS 111->139|PS00061|ADH_SHORT|PDOC00060| BL:PDB:NREP 1 BL:PDB:REP 30->211|2cfcA|2e-19|37.0|173/250| RP:PDB:NREP 1 RP:PDB:REP 26->165|3ce6B|6e-28|10.1|139/485| RP:PFM:NREP 1 RP:PFM:REP 31->141|PF00106|4e-10|41.8|110/169|adh_short| HM:PFM:NREP 1 HM:PFM:REP 10->142|PF00106|9.8e-25|27.8|126/167|adh_short| GO:PFM:NREP 2 GO:PFM GO:0008152|"GO:metabolic process"|PF00106|IPR002198| GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF00106|IPR002198| RP:SCP:NREP 1 RP:SCP:REP 2->197|1pwxA|3e-26|20.2|188/252|c.2.1.2| HM:SCP:REP 2->208|1zemA1|1.3e-47|34.6|205/0|c.2.1.2|1/1|NAD(P)-binding Rossmann-fold domains| OP:NHOMO 10754 OP:NHOMOORG 1064 OP:PATTERN --1-12366575645316-111-183352647-1---------11143--522-11--1-2-643-44 FFP2X2-3226554akZMM-Mh55b*MLMMMSl***Xl**5Q9zLFC65C72GBD4-A11DEP4GBRWRLD-222---2274Q1121-45771422---63G489d6P6D1111111-111111354389744566BDDHI222F7EAGE54776331214332338ECP7211122212122FA688551E5EAAAAA9BCBBDAAACF9JJAF9A87DDEFCA555464CU5443333233444337776A729276251218944556642667555454555332333333333333544544555555333222333452568333333343551553465431115611264123225333236312828WAAL11111J8sTa546KHJHDDEFECDFDFFL-HJPGFdHLSiP1dVVLcWcpmlmdNS9E9GGPJ8HICFD55555555GIK949B61111111111----11---------1---48cqB5CNHCOjXZejdJMMNKWWfdNPNOALxMmQlbR25JLHICFBBMDRGZO5C72434B52222222--6JB46M6C31121-133212652B44646978LS14-111------1-2-------111114476669975C523755629A8677548662A1-2234511-1117AEG6E69BB7999999-B89A989AAAB89A99A98CHEA84588667878789767677H78676592-5888788787781-154645499991FEFC111515111112232DDDFE9B489H6LLEJGKLNHFILLFHHK3232232221445B6566568389BCCBABB55541211133887699--------1-4----2---2-1------2-------45321565652C3 11--LEA-1-2-367IMCGRFKIWPYTBD99ACCCA6FABACCAA8AGDHKWkbBFDA999C149-112611445-1---16556533-CTCM7E64632756987-CE6yUaKKN874936A6GH6L6LmE-GEJ8474B87J75A943C33FAKHHLSTL7UIGAICJRDIEL5963b3315DDFDaCMB69F57A8 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 237 STR:RPRED 100.0 SQ:SECSTR EEEEcccHHHHHHHHHHHHHTTccEGGGccEEEEcccccccccHHHHHHccTTcEEEEccccGGGccHHHHHHTTcEEEEEETTEEEEEcTTTccEEEEEGEGGccHHHHHcccccHHHHHHcGGGccccEEEccHHHHHHHHHHHHHHHTcccccccHHHHHHHGHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHccccccEEEcccTTHHHHHHHHTHHHccTTccHHHTT PSIPRED cEEcccHHHHHHHHHHHHHccccEEEEEEcccccHHHHHHHHHHHHHHHccccEEEEcccccccccHHHccHHHHHHHHHHHcHHHHHHHHHHHHHHHHcccccEEEEEccHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHHccEEEEEcccccccHHHHHHcccccHHHHHHHHHcccccccccHHHHHHHHHHHHcHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHccccc //