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Streptomyces avermitilis MA-4680 (save0)
Gene : pteA5
DDBJ      :pteA5        modular polyketide synthase
Swiss-Prot:             

Homologs  Archaea  0/68 : Bacteria  859/915 : Eukaryota  185/199 : Viruses  0/175   --->[See Alignment]
a.28.1a.38.2c.1.19c.19.1c.2.1c.69.1c.95.1d.129.7d.358.1
:3352 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   36->887 2qo3B PDBj 0.0 53.2 %
:BLT:PDB   953->1212 2fr0A PDBj 2e-42 39.0 %
:BLT:PDB   1300->1402 2fr0A PDBj 4e-19 45.6 %
:BLT:PDB   1430->1495 2ju1A PDBj 1e-11 48.5 %
:BLT:PDB   1527->2415 2hg4F PDBj 0.0 49.7 %
:BLT:PDB   2476->2946 2fr0A PDBj 4e-55 38.6 %
:BLT:PDB   2975->3049 2ju1A PDBj 2e-09 42.7 %
:BLT:PDB   3112->3333 1mo2A PDBj 8e-28 33.8 %
:RPS:PDB   36->460 2c9hA PDBj 2e-90 24.1 %
:RPS:PDB   557->854 3eenA PDBj 2e-76 35.4 %
:RPS:PDB   1038->1185 1a4iB PDBj 3e-08 12.4 %
:RPS:PDB   1183->1321 2e6gC PDBj 4e-12 10.1 %
:RPS:PDB   1299->1403 3e03A PDBj 6e-04 22.0 %
:RPS:PDB   1457->1955 1e1cA PDBj 2e-91 10.8 %
:RPS:PDB   2009->2090 3dsgB PDBj 4e-11 16.9 %
:RPS:PDB   2062->2373 3eenA PDBj 3e-58 22.3 %
:RPS:PDB   2469->2658 3d64A PDBj 7e-13 9.7 %
:RPS:PDB   2723->2845 2e6gI PDBj 3e-15 13.5 %
:RPS:PDB   2973->3057 3ce7A PDBj 2e-13 8.2 %
:RPS:PDB   3132->3250 3bf8A PDBj 2e-08 11.2 %
:RPS:SCOP  36->464 1e1cA1  c.1.19.1 * 2e-86 10.4 %
:RPS:SCOP  562->802 1nm2A1  c.19.1.1 * 2e-63 21.3 %
:RPS:SCOP  780->887 2hh8A1  d.358.1.1 * 2e-19 10.5 %
:RPS:SCOP  948->1137 2fr0A2  c.2.1.2 * 9e-29 44.1 %
:RPS:SCOP  1153->1402 2fr0A1  c.2.1.2 * 8e-15 34.3 %
:RPS:SCOP  1452->2045 1e1cA1  c.1.19.1 * e-104 10.0 %
:RPS:SCOP  2066->2323 1nm2A1  c.19.1.1 * 6e-45 15.4 %
:RPS:SCOP  2305->2429 2hh8A1  d.358.1.1 * 4e-18 8.7 %
:RPS:SCOP  2475->2682 2fr0A2  c.2.1.2 * 5e-27 36.8 %
:RPS:SCOP  2689->2946 2fr0A1  c.2.1.2 * 2e-15 34.9 %
:RPS:SCOP  2987->3067 1j3mA  d.129.7.1 * 9e-13 21.0 %
:RPS:SCOP  3113->3333 1jmkC  c.69.1.22 * 3e-16 18.9 %
:HMM:SCOP  2->35 1pzrA_ a.38.2.1 * 7.7e-07 44.1 %
:HMM:SCOP  27->409 1tedA_ c.95.1.2 * 1.9e-103 48.0 %
:HMM:SCOP  559->854 1nm2A1 c.19.1.1 * 9.7e-74 51.5 %
:HMM:SCOP  947->1147 2fr1A2 c.2.1.2 * 1.3e-41 43.1 %
:HMM:SCOP  1150->1414 1gz6A_ c.2.1.2 * 1.2e-48 31.5 %
:HMM:SCOP  1428->1543 1klpA_ a.28.1.1 * 2.4e-30 44.7 %
:HMM:SCOP  1519->1901 1tedA_ c.95.1.2 * 8.2e-101 48.5 %
:HMM:SCOP  2065->2368 1mlaA1 c.19.1.1 * 5.7e-65 45.1 %
:HMM:SCOP  2474->2685 2fr1A2 c.2.1.2 * 6.1e-43 42.3 %
:HMM:SCOP  2690->2947 1gz6A_ c.2.1.2 * 9.3e-50 32.3 %
:HMM:SCOP  3011->3335 1kezA_ c.69.1.22 * 1.2e-39 29.2 %
:RPS:PFM   37->285 PF00109 * ketoacyl-synt 7e-68 61.4 %
:RPS:PFM   294->411 PF02801 * Ketoacyl-synt_C 1e-34 70.1 %
:RPS:PFM   563->823 PF00698 * Acyl_transf_1 5e-63 58.2 %
:RPS:PFM   1157->1212 PF08659 * KR 2e-13 69.6 %
:RPS:PFM   1269->1332 PF08659 * KR 6e-17 65.6 %
:RPS:PFM   1458->1496 PF00550 * PP-binding 1e-05 48.7 %
:RPS:PFM   1529->1777 PF00109 * ketoacyl-synt 7e-61 56.6 %
:RPS:PFM   1786->1903 PF02801 * Ketoacyl-synt_C 8e-32 64.4 %
:RPS:PFM   2067->2349 PF00698 * Acyl_transf_1 2e-51 44.2 %
:RPS:PFM   2712->2846 PF08659 * KR 8e-25 51.9 %
:RPS:PFM   2984->3049 PF00550 * PP-binding 3e-07 43.1 %
:RPS:PFM   3123->3320 PF00975 * Thioesterase 5e-10 31.3 %
:HMM:PFM   35->285 PF00109 * ketoacyl-synt 4e-99 58.1 246/253  
:HMM:PFM   1526->1777 PF00109 * ketoacyl-synt 9e-96 56.3 247/253  
:HMM:PFM   563->861 PF00698 * Acyl_transf_1 8.2e-65 39.8 299/318  
:HMM:PFM   2068->2387 PF00698 * Acyl_transf_1 1.1e-101 45.9 316/318  
:HMM:PFM   1157->1332 PF08659 * KR 1e-62 58.0 176/181  
:HMM:PFM   2697->2875 PF08659 * KR 7.9e-65 58.7 179/181  
:HMM:PFM   293->411 PF02801 * Ketoacyl-synt_C 1.5e-51 65.3 118/119  
:HMM:PFM   1785->1903 PF02801 * Ketoacyl-synt_C 3.1e-49 61.9 118/119  
:HMM:PFM   1438->1504 PF00550 * PP-binding 1.2e-16 36.4 66/67  
:HMM:PFM   2991->3049 PF00550 * PP-binding 1.1e-12 37.9 58/67  
:HMM:PFM   3123->3333 PF00975 * Thioesterase 5.5e-23 23.9 209/229  
:HMM:PFM   3->28 PF08990 * Docking 2.6e-12 57.7 26/27  
:BLT:SWISS 3->1212,1269->1399,1448->1495,1527->3333 OL56_STRAT 0.0 45.5 %
:PROS 1463->1478|PS00012|PHOSPHOPANTETHEINE
:PROS 3008->3023|PS00012|PHOSPHOPANTETHEINE
:PROS 198->214|PS00606|B_KETOACYL_SYNTHASE
:PROS 1690->1706|PS00606|B_KETOACYL_SYNTHASE
:PROS 432->463|PS00969|ANTENNA_COMP_BETA
:TM
:COIL
:REPEAT 2|36->1496|1528->3041
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID BAC68125.1 GT:GENE pteA5 GT:PRODUCT modular polyketide synthase GT:DATABASE GIB00135CH01 GT:ORG save0 GB:ACCESSION GIB00135CH01 GB:LOCATION complement(498846..508904) GB:FROM 498846 GB:TO 508904 GB:DIRECTION - GB:GENE pteA5 GB:PRODUCT modular polyketide synthase GB:NOTE filipin gene cluster GB:PROTEIN_ID BAC68125.1 LENGTH 3352 SQ:AASEQ MSSKEDRLLEYLKRVTGDLRQVRERLREVEEKDDDPIAIVGMACRYPGGVRSPEDLWHLVAAGGDAVGDFPADRGWDVEGIYDPDPDARGKTYARRGGFLYEAGEFDPGFFGISPREAVAMDPQQRLLLETTWETFERAGIDAESVRGSRTGVFVGSGYQDYVNLLVGVGGESDGHLGTGNSASVMSGRIAYTFGLEGPAVTVDTACSSSLVALHWAIQALRNGECSMALAGGVQVMTTPTAFVEFSRQRGLAPDGRCKAFGAGADGTGWAEGVGMLLVERLSDAVRNGHEVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRQALASAGLSPAQIDVVEAHGTGTTLGDPIEAQALLATYGRERTEDRPLWLGSLKSNIGHSQAAAGVGGIIKMVMAMRHGVLPQTLHVDEPTPHVDWSAGAVRLLTEAVEWPETHHPRRAAVSSFGVSGTNAHTIIEQAPPAQDEGPAGALVDGPLAWVLSARSDAALRAQAARLRPSARGEVRPQDIGLSLATTRAAMRHRAAVVGDNREELLSGLEDLATGTPSSRVLLGRPAGGKTGFLFSGQGSQRIGMGRELYAAYPVFAAAYDEVCAHLDAPVDVDAETLHRTGGTQPALFAVEVALFRLLESLGVRPDFVVGHSVGEIAAAHVAGALSLDDAAKLVSARAALMQALPAGGAMVAVQATEEEVLPHLTDGVSIAAVNGPSSVVVSGDETAALAIAAGFAEQGRKTSRLKVSHAFHSPLMDPMLAEFAEVVRGLAFEQPQLPVVSNLTGQPVEAYTPEYWVRHVRETVRFADSVRTLHDLGVKTFIEIGPGGVLSGMAQGCADDIVTVPVLRADRPERQAVVTALAHLHTHGVSVDWHSFFAGARRTDLPTYAFQREWYWVDAPESAAAEADPVDAEFWETVERGDLQALAETLDIGAGDTFGDVLPRLSSWRRQRKEQSTVDDRRYRESWKRLGELGPAGIGGTWLLAVPAEENEQTAAVRTALTARGATLKTLVVDAASHRAGLAGELAGIGPVDGVLSLLVNGDPVLPTLLLVQALGDAGVDAPLWCLTSGAVAVSGSDAVRDARHAQVWGLGRTVALELPRRWGGLIDLPESVDDQAAVRLADVLEQALTGRWEEDQLAVRASGVFARRLAHAPARAATRRWQPRGTVLITGGTGALGGHVARWLARGGAEHLVLTSRRGADAPGAAALRDELEVLGARVTFAACDVADRDAVAALLAQHVFTAVVHAAGVADAGTVDATTPAAFAAALAAKVGGAAHLDELLGDQELDAFVLFSSISGVWGSGGQAAYAAGNAFLDGLARQRRDRGLTATAVSWGPWADGGMVADGDDEERLRRRGLRAMTPASAITSLQRALDRDETLLTVADVDWSRFIVPFTLGRPSPLLGDLPEVRAALAVDTPAAGHGSGALAESLAALSHQDRARALVDLVRTHAAAVLGHRGAGAVEADRPFRDIGFDSLTAVELRNRINKATGLSLPATLIFDHPTAADLAAHLLAELTGGQHEAVAAAATAAVLDEPIAIIGMACRYPGGVRSPEDLWELVASGRDAISRFPGNRGWDVEALYHPDPDHPGTTYTTQGGFLHDADEFDPAVFGISPREAVAMDPQQRLLLDTTWEAFERARIAPHAMRSTTTGVFVGSGYQDYTGRPLKVPDGVEGYIPSGNAASVISGRLSYTFGLQGPSVTVDTACSSSLTALHLAMQALRGGECSMALAGGVMVMAGPSAFTMSSRQRALSADGRCKAFSSSADGTGFAEGVGLVLLERLSDARRNGHEVLAVVRGSAVNQDGASNGLTAPSGKAQQQVIRQALANARLAPDEVDAVEAHGTGTRLGDPIEAQALLATYGKERSEGRPLWLGSLKSNIGHTQAAAGVGGVIKMVMAIRNGILPQTLHVDEPTPHVDWAGGNVRLLTEQTAWPDQDRPRRAAVSSFGMSGTNVHTIIEQAPQTATAAEVEQPPAAQDATAAQPLDVFPWALSAKTDRSLREQARRLLNHLDRTEGLTLPDVGRALVTTRTQLEQRAVVVGQDRHELRAGLAALADGKPADTVVQGTASASGKVAFVFPGHGSQWTEMARELLDTSPVFAEQAKACAEAFAPYLDWPLLDVLRAEPDAPDVADVEVAQPALFTVMVSLAALWRSYGVTPAAVVGHSQGEVAAAYVAGALTLDDAARIVALRSRSLTKLIGKGAMLAIAMPAERVRARLEKYGDRLSVAAVNGPAALTVSGEPDAVDELLAELEAEGVRVRKVRGATGAGHSTQVESLRPELLHLLAPVAPGAAEVPYYSTVTGTVLDTTTLDAEYWYRNARHTVEFEWTVRTLLADGHGVFVECSPHPLLADAVQEIAEETGADAVTGSSLRRGQGGMDRFLRSVSELHVSGVHVDLTAPFAGRPVRRVDLPTYAFQPQRYWLESADPVPAGTDPVEAGFWELVENTDLSGLADELGADDAALVGPALPVLSAWRRRSREKSTVDGWRYRVSFRRLTDHAAPGLNGLWLAVLPAGLADEQWAPCVVGVLAAHGAKVRVVELPVDCDRSQAAKRLAEELRGEQPAGVLSMLGLAPGCHPAHPTLSASLATTVTLLQALGDVDVQAPLWCATRGAVSTGVTDPLRDAGQAQLWGLGVVAALELPRRWGGLVDLPEELDEHALRRLAGVLAQHDEDQLAVRVDGVYGRRMVRARPADEESATPWKPRGTVLITGGTGGVGRHLARWLAGAGAQHLVLTSRSGPDAPGAQELHAELTALGAEVTIAACDMADRAAVARLLAGIESRHPLTAVLHAAGTARSSMLADAGLDEFAEAAASKVTGAIHLDELLDGRELDAFVLFASGAGVWGSGGQASYASANAFLDALALRRRARGLTATSVAWGGWAGGGMVDDAVQERGERRGLGVMAPELAISALREAVEHDEAALTVAPIDWEKFLPAFTVGRPSPLLADLPDVQRLLEAEQAVGEGTSAGAALATELAALAPVEQEERLLEHVRAQSAVVLGHASAEDVLPTAHFLELGFDSLTAIDLRRRLSAATGLRLPSGLAFDHPTPARLAKHLLTRLQSTGSAAAEERPADMLVQLYRHASENGTAAEAMGMLMEAARFRPSFERPEELDRRPAPVRLSQGDHPLALMCFSPYVVPAGAHQYARFAAPFRDRLDVWALVHPGYEKGEPVPSDPDVVFRLHAQTVRECAGGKPAVLLGYSSGGWIAHGVAAHLEAMGERPAAVVMVDSFSREVPFDHQVLNAMAQAHSQRLDFMRSGGEQLTAMGRYMRLFDDWAAPQIAAPTLLVRASEPMLAGAGDGDGRAAPPEHVDTIVEVTGNHYSMLEDHAGTTAAAVDSWLADAVTDASGPVAPADATTA GT:EXON 1|1-3352:0| BL:SWS:NREP 1 BL:SWS:REP 3->1212,1269->1399,1448->1495,1527->3333|OL56_STRAT|0.0|45.5|3171/3519| PROS 1463->1478|PS00012|PHOSPHOPANTETHEINE|PDOC00012| PROS 3008->3023|PS00012|PHOSPHOPANTETHEINE|PDOC00012| PROS 198->214|PS00606|B_KETOACYL_SYNTHASE|PDOC00529| PROS 1690->1706|PS00606|B_KETOACYL_SYNTHASE|PDOC00529| PROS 432->463|PS00969|ANTENNA_COMP_BETA|PDOC00748| COIL:NAA 25 COIL:NSEG 1 COIL:REGION 8->32| TM:NTM 1 TM:REGION 2125->2147| NREPEAT 1 REPEAT 2|36->1496|1528->3041| SEG 18->35|dlrqvrerlreveekddd| SEG 482->502|lsarsdaalraqaarlrpsar| SEG 515->526|attraamrhraa| SEG 888->904|vdapesaaaeadpvdae| SEG 1138->1152|arrlahaparaatrr| SEG 1214->1229|aacdvadrdavaalla| SEG 1234->1268|tavvhaagvadagtvdattpaafaaalaakvggaa| SEG 1337->1350|dgddeerlrrrglr| SEG 1411->1428|aaghgsgalaeslaalsh| SEG 1497->1508|aadlaahllael| SEG 1515->1524|avaaaataav| SEG 1964->1976|qppaaqdataaqp| SEG 2091->2103|faeqakacaeafa| SEG 2239->2247|ellaeleae| SEG 2292->2304|tvtgtvldtttld| SEG 2440->2455|dlsgladelgaddaal| SEG 2574->2589|tlsaslattvtllqal| SEG 2697->2709|gtvlitggtggvg| SEG 2754->2766|aacdmadraavar| SEG 2847->2865|anafldalalrrrarglta| SEG 2869->2877|awggwaggg| SEG 2955->2972|gegtsagaalatelaala| SEG 3082->3093|aaeamgmlmeaa| SEG 3289->3299|agagdgdgraa| BL:PDB:NREP 8 BL:PDB:REP 36->887|2qo3B|0.0|53.2|840/873| BL:PDB:REP 953->1212|2fr0A|2e-42|39.0|256/468| BL:PDB:REP 1300->1402|2fr0A|4e-19|45.6|102/468| BL:PDB:REP 1430->1495|2ju1A|1e-11|48.5|66/95| BL:PDB:REP 1527->2415|2hg4F|0.0|49.7|835/859| BL:PDB:REP 2476->2946|2fr0A|4e-55|38.6|464/468| BL:PDB:REP 2975->3049|2ju1A|2e-09|42.7|75/95| BL:PDB:REP 3112->3333|1mo2A|8e-28|33.8|216/251| RP:PDB:NREP 12 RP:PDB:REP 36->460|2c9hA|2e-90|24.1|403/426| RP:PDB:REP 557->854|3eenA|2e-76|35.4|294/314| RP:PDB:REP 1038->1185|1a4iB|3e-08|12.4|145/295| RP:PDB:REP 1183->1321|2e6gC|4e-12|10.1|127/225| RP:PDB:REP 1299->1403|3e03A|6e-04|22.0|100/262| RP:PDB:REP 1457->1955|1e1cA|2e-91|10.8|461/727| RP:PDB:REP 2009->2090|3dsgB|4e-11|16.9|77/95| RP:PDB:REP 2062->2373|3eenA|3e-58|22.3|305/314| RP:PDB:REP 2469->2658|3d64A|7e-13|9.7|186/462| RP:PDB:REP 2723->2845|2e6gI|3e-15|13.5|111/227| RP:PDB:REP 2973->3057|3ce7A|2e-13|8.2|85/90| RP:PDB:REP 3132->3250|3bf8A|2e-08|11.2|116/255| RP:PFM:NREP 12 RP:PFM:REP 37->285|PF00109|7e-68|61.4|241/245|ketoacyl-synt| RP:PFM:REP 294->411|PF02801|1e-34|70.1|117/118|Ketoacyl-synt_C| RP:PFM:REP 563->823|PF00698|5e-63|58.2|261/297|Acyl_transf_1| RP:PFM:REP 1157->1212|PF08659|2e-13|69.6|56/181|KR| RP:PFM:REP 1269->1332|PF08659|6e-17|65.6|64/181|KR| RP:PFM:REP 1458->1496|PF00550|1e-05|48.7|39/67|PP-binding| RP:PFM:REP 1529->1777|PF00109|7e-61|56.6|241/245|ketoacyl-synt| RP:PFM:REP 1786->1903|PF02801|8e-32|64.4|117/118|Ketoacyl-synt_C| RP:PFM:REP 2067->2349|PF00698|2e-51|44.2|281/297|Acyl_transf_1| RP:PFM:REP 2712->2846|PF08659|8e-25|51.9|135/181|KR| RP:PFM:REP 2984->3049|PF00550|3e-07|43.1|65/67|PP-binding| RP:PFM:REP 3123->3320|PF00975|5e-10|31.3|195/219|Thioesterase| HM:PFM:NREP 12 HM:PFM:REP 35->285|PF00109|4e-99|58.1|246/253|ketoacyl-synt| HM:PFM:REP 1526->1777|PF00109|9e-96|56.3|247/253|ketoacyl-synt| HM:PFM:REP 563->861|PF00698|8.2e-65|39.8|299/318|Acyl_transf_1| HM:PFM:REP 2068->2387|PF00698|1.1e-101|45.9|316/318|Acyl_transf_1| HM:PFM:REP 1157->1332|PF08659|1e-62|58.0|176/181|KR| HM:PFM:REP 2697->2875|PF08659|7.9e-65|58.7|179/181|KR| HM:PFM:REP 293->411|PF02801|1.5e-51|65.3|118/119|Ketoacyl-synt_C| HM:PFM:REP 1785->1903|PF02801|3.1e-49|61.9|118/119|Ketoacyl-synt_C| HM:PFM:REP 1438->1504|PF00550|1.2e-16|36.4|66/67|PP-binding| HM:PFM:REP 2991->3049|PF00550|1.1e-12|37.9|58/67|PP-binding| HM:PFM:REP 3123->3333|PF00975|5.5e-23|23.9|209/229|Thioesterase| HM:PFM:REP 3->28|PF08990|2.6e-12|57.7|26/27|Docking| GO:PFM:NREP 4 GO:PFM GO:0048037|"GO:cofactor binding"|PF00550|IPR006163| GO:PFM GO:0048037|"GO:cofactor binding"|PF00550|IPR006163| GO:PFM GO:0009058|"GO:biosynthetic process"|PF00975|IPR001031| GO:PFM GO:0016788|"GO:hydrolase activity, acting on ester bonds"|PF00975|IPR001031| RP:SCP:NREP 12 RP:SCP:REP 36->464|1e1cA1|2e-86|10.4|394/559|c.1.19.1| RP:SCP:REP 562->802|1nm2A1|2e-63|21.3|230/243|c.19.1.1| RP:SCP:REP 780->887|2hh8A1|2e-19|10.5|95/127|d.358.1.1| RP:SCP:REP 948->1137|2fr0A2|9e-29|44.1|186/209|c.2.1.2| RP:SCP:REP 1153->1402|2fr0A1|8e-15|34.3|249/259|c.2.1.2| RP:SCP:REP 1452->2045|1e1cA1|e-104|10.0|548/559|c.1.19.1| RP:SCP:REP 2066->2323|1nm2A1|6e-45|15.4|237/243|c.19.1.1| RP:SCP:REP 2305->2429|2hh8A1|4e-18|8.7|109/127|d.358.1.1| RP:SCP:REP 2475->2682|2fr0A2|5e-27|36.8|204/209|c.2.1.2| RP:SCP:REP 2689->2946|2fr0A1|2e-15|34.9|258/259|c.2.1.2| RP:SCP:REP 2987->3067|1j3mA|9e-13|21.0|81/127|d.129.7.1| RP:SCP:REP 3113->3333|1jmkC|3e-16|18.9|206/222|c.69.1.22| HM:SCP:REP 2->35|1pzrA_|7.7e-07|44.1|34/60|a.38.2.1|1/1|Docking domain B of the erythromycin polyketide synthase (DEBS)| HM:SCP:REP 27->409|1tedA_|1.9e-103|48.0|342/0|c.95.1.2|1/2|Thiolase-like| HM:SCP:REP 559->854|1nm2A1|9.7e-74|51.5|237/254|c.19.1.1|1/2|FabD/lysophospholipase-like| HM:SCP:REP 947->1147|2fr1A2|1.3e-41|43.1|197/0|c.2.1.2|1/4|NAD(P)-binding Rossmann-fold domains| HM:SCP:REP 1150->1414|1gz6A_|1.2e-48|31.5|254/302|c.2.1.2|1/2|NAD(P)-binding Rossmann-fold domains| HM:SCP:REP 1428->1543|1klpA_|2.4e-30|44.7|114/115|a.28.1.1|2/3|ACP-like| HM:SCP:REP 1519->1901|1tedA_|8.2e-101|48.5|342/0|c.95.1.2|2/2|Thiolase-like| HM:SCP:REP 2065->2368|1mlaA1|5.7e-65|45.1|235/0|c.19.1.1|2/2|FabD/lysophospholipase-like| HM:SCP:REP 2474->2685|2fr1A2|6.1e-43|42.3|208/0|c.2.1.2|3/4|NAD(P)-binding Rossmann-fold domains| HM:SCP:REP 2690->2947|1gz6A_|9.3e-50|32.3|248/302|c.2.1.2|2/2|NAD(P)-binding Rossmann-fold domains| HM:SCP:REP 3011->3335|1kezA_|1.2e-39|29.2|264/267|c.69.1.22|3/3|alpha/beta-Hydrolases| OP:NHOMO 5570 OP:NHOMOORG 1044 OP:PATTERN -------------------------------------------------------------------- 4482L2233341-1FEFNN-NFCCVBOMNNOFHEDE83573NEM112-232234311411NI21X4Ra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aQ342432222222122222222222222444442375434677777677777777777772-33332211111E3D5364366D3AA433-733333434474633333554694CA634333333333333336334333332868788767787223546444766853E4622224222222233233553243326C66479G88354744A9C522222222345572333335755665555544433333323--1111--------2-2-------------------------22222222222A2 2152jy4-211-2238DRCYHMMakVW333665LNE8BCCCCB555OKHRHJFHCBWSG999222111-211212111-112222222-1D3D212------6222-1N3V6554413221233512314B3-3242221323521222-41162632333339C2B558E66A9335O*73KFP958BN68444223* ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 3227 STR:RPRED 96.3 SQ:SECSTR ####cHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccEEEEEEEEEETTEEccHHHHHHHHHTTcccEEEcccGGccccTTcGTTccccccccEEEcccccccTTcccGGGTHccTTHHHHccHHHHHHHHHHHHHHHHHTcccccHHHHHTEEEEHHHHHHHHHHHHHcGGGccTTHHHHHcTTHHHHHHHHHHTccccEEccccGGHHHHHHHHHHHHHHHHTcccEEEEEEEEccccHHHHHHHHHTTcccTTTcccTTcTTccccccccEEEEEEEEEHHHHHHHTccccEEEEEEEEEEcccccccccTTcHHHHHHHHHHHHHHTccGGGEEEEEccccccHHHHHHHHHHHHHHHGGGGHGGGTcEEEccHHHHcccGGGHHHHHHHHHHHHHHHTEEcccTTcccccTTccccGcccccccccEEccEcccccEEEEEEEETTTEEEEEEEEcccHHHHHTTcccGGGcccTTccccccHHHHHHHHHHHHTTTccHHHHHHHHHHHHTTccTTTTccccTccGGGcTTGGGccTTcTTTTHHHHHHHHHHHHHHHHHHccTTccccHHHHHHHHcHHHHHHHHHHHTTccccccccccccccGGGccHHHHGGGcccEEGGGTEEccccccEEcHHHHHHHHHHHTTccHHHHHHHHHHHHHTTcHccTTEEEEEEHHHHHHHHHHTTccEEEEEEEETTEEEEEEEHHHHHHHHHHHHTTTcccEEccccccTTcGGGHHHHHHHHHHHTTccccccccccEETTTTEEcHHHHHHHHHHHHHccEEHHHHHHHHHHTTccEEEEcccccHHHHHHHHHcTEEEEcccHHHHHHHHccEHHHHccEEccccEEETTTTccccccTTccccEEEETTcc#######################################################cccGGGHHHHHHHHHHHGGGcHHHHHHHHHTTTTcTccccHHHHHHHHHHHHTTcEEEEEcccccccHHHHHHHHHTTccEEccTTccHTTcccTcEEEEEEEcccHHHHHHHHHHHHHHHHHEEEEEEEcTTccHHHHHHHHHHHHHcTTccEEEEcccccccccccHHHHHHTccGGGcTTcccHHHHHHHHTTccccccccHHHHHHHHHHcEEEEEcccTTTHHHHHHHHHHTTcEEEEEcTTcccHHHHHTTcHcEEEEccccTTcEEccccccccccccEEEcccccEEcccccccEEEEcccHHHHHHHHHHHHccccEEEEEEEEccccGGEEEEccccccccccccHHHHHHHHHHHHHHHHHHHHccEEEEEETTTcccccccGGGcccTHHHHHHHHcccTTccHHHHccEEEEcccEEEEEEccHHHHHHHTccccccccccEEEEEEEcccEEEEEEGGGccTTccccHHHHHTTccccHHHHHHHHcEEcTTccEEccccGGcccccccccTTHHHHHHcHHHHHHTccccEEcTTccEEcccccGGGGTTcccTTcTTcTTcccccHHHHcccEEccEEccccHHHHHHHHHHHHHTTcccEEEEccEcHHHHHTTccTTcTTTGGGTTccccccccHHHHHHHcTTccTTTcEEccTTHHHHHHHHHHHHHHHTccGGGcEEEEcccHHHHHHTTccHHHHHHHHHHTTccccHHHHHHHHHHHHHHHHHHcTTEEcEEEEcHHHHHHTTTccccHHHHHHHHHHHHHcHHHHHHHHHHHHHHTTccGGGTGGGEEEEEcccHHHHHHHHHHHHHHHHHHHHTTccHccGGGGcccEEEEEccTTcccccTTHHHHHHHHHHHHHHHHTccEEEcccTTTTTccccHHHHHHHHcccccTTHHHHHHHHHTcccccccTTTTcHHHHHHHHHHHHHHHHHHHHHHHTTcHHHHccHHTTHHHHHHHHHHHHHHHHHHHTcccccTTTcccccccccccEEEEEccGGGGGGGHHHHHHHccEEEcTTccHHHHHHHHHHHTHHHHHHHHTcTTccccHHHHHHHHHHHTTcccccccccHHHHHHHHHHTTTTGGGccTTccHHHHHHHTTccTTTcccccTccGGGcTTGGGccTTcTHHHHHHHHHTTTHHHHHHHHHHHHHHHHHHHHccccTTccccHHHHHHHHTccHHHHHHHHHHHHHHHHHHHHHHHHHHTTccHHHHHHTHHHHHHHHHHHHHccGGGTTcccccccccccccGGGcccccccccccccHHHHHHHHHTTTccHHHHHHHHHGGGGccEEcHHHHcccEEccccTTccccHHHHHHHHcccEEEEcTTccEEEEcTTccEEcHHHHHHHHcHHHHHHHcccccHHHHHHHHHcTTcEEEEcEEccHHHHHHHHHHHEEEccEEEccccEEETTTTccccccccTTccccEEEETTccEEcEEE################################################ccccGGGHHHHHHHHHHHGGGcHHHHHHHHHTTTTcTTTccccHHHHHHHHHHHHTTcEEEEEccccccccHHHHHHHHHHHHHTTccEEccTTccHHHHHHHHHHTTcccTTccccEEEEcccHHHHHHHHHHHHHHcGGGGTccccHHHHHHHHHHHHHHTTcTTTTHHHHTTcccEEEccHHHHHHHHHTTTTcHHHHHHHHHHTccccccEEcccccccccEEEEEEEcTTcccccEEETTccHHHHHHEEEEEEccccTTcHHHHHHHHHHGGGcEEEEEEEEcccccccEEEEcccccEccccccEEEEEccHHHHHHHHHHHcccccEccccEHHHHEEEEEEEccccGGGGGGcHHHHHHHHHHTTcEEccccEEEEEccccccEEEEcccccGGGccEEEEEEcTTccEEEEEEcccGGGccTTcHHHcHHHTTEEEEEEcccccccGHHHTccccccccccEEEEEEEcccccEEEEEGGGccTTccccHHHHHHHHHHHHHHHHHHTTccTTccccTTccGGGcccTTcccccHHHHHHHHHHHHHHHTccccHHHHTTcccHHHHHHHHHHHHHcccccccc###ccHHHHHHHHHHHHTccHHHHHHHHHHHTTccccccccccccccccEEEEccccEEEEEEEccccTTccTTTTHHHHHHHTTTccEEEEccTTcTTccccccccHHHHHHHHHHHHHHHTcccEEEEEETHHHHHHHHHHHHccccGGGEEEEEEEccccccccccccHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHTGGGccccEEEEEETTcccccTTHHHHHHHHcTTcccEEccccTTTcTTHHHHHHHHHHHHHHHH############### DISOP:02AL 1-5, 15-36, 895-898, 1404-1421, 1520-1522, 1961-1971, 2421-2425, 2947-2971, 3056-3084, 3348-3352| PSIPRED cccHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccEEEEEEEEEcccccccHHHHHHHHHccccEEEcccccccccHHHHcccccccccccccccccEEccHHcccHHHHcccHHHHHHHcHHHHHHHHHHHHHHHHccccccccccccEEEEEEcccHHHHHHHHcccccccccEEHHHHHHHHHHHHHHHHcccccEEEEEcHHHHHHHHHHHHHHHHHcccccEEEEEcccccccHHHHHHHHHcccccccccccccccccccEEEEcEEEEEEEEcHHHHHHcccEEEEEEEEEEEcccccccccccccHHHHHHHHHHHHHHccccHHHccEEEEEEcccccccHHHHHHHHHHHcccccccccEEEEcccccccHHHHHHHHHHHHHHHHHHHcccccccccccccccccccccccEEEccccccccccccEEEEEEEccccccHHEEEEEEccccccccccccccccccEEEEEccccHHHHHHHHHHHHHHHcccccHHHHHHHHHccccccccEEEEEEccHHHHHHHHHHHHcccccccEEEccccccEEEEEEccccccHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHccccEEEEEEccHHHHHHHHHHccccHHHHHHHHHHHHHHHHHcccccEEEEEcccHHHHHHHHcccEEEEEEEccccEEEEccHHHHHHHHHHHHHcccEEEEEcccccccHHHHHHHHHHHHHHHHccccccccEEEEEcccccccccccHHHHHHHHHHHHHHHHHHHHHHHccccEEEEEccHHHHHHHHHHHccccEEEEEccccccHHHHHHHHHHHHHHccccccHHHcccccccccccccccccHHcccccccccccccccccccccccccccHHHHHHHccccccccccccHHHHHHHHHHHHHcHHHHHHHHHHHHcccccccccccccccEEEEEEcccccHHHHHHHHHHccccccEEEEcccccccHHHHHHHHcccccccEEEEcccccHHHHHHHHHHHHHccccccEEEEEccccEEcccccccccHHHHHHHHHHHHHHHHccccEEEEEEccccccHHHHHHHHHHHHHHHcccccccEEEEEccEEEEEEEEcccccccccccccccEEEEEEcccHHHHHHHHHHHHccccEEEEEEccccccHHHHHHHHHHHHcccEEEEEEcccccHHHHHHHHHcccccEEEEccccccccHHHHccHHHHHHHHHHHHHHHHHHHHHcccccccEEEEHHHHHHHcccccHHHHHHHHHHHHHHHHHHHcccccEEEEEccccccccccccHHHHHHHHHcccccccHHHHHHHHHHHHHccccEEEEEcccHHHHHHHHHHccccHHHHHHHHHHHHHcccccccccccHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHccccHHHccccccHHHHcccHHHHHHHHHHHHHHHcccEEEHHHHccccHHHHHHHHHHHHcccccHHHHHHHHcccccccEEEEEEEcccccccccHHHHHHHHHccccEEEcccccccccHHHHcccccccccccccccccccccHHHccHHHHcccHHHHHHHcHHHHHHHHHHHHHHHcccccccccccccEEEEEEccccHHHHHHHccHHHcccEEHHHHHHHHHHHHHHHHHcccccEEEEEcHHHHHHHHHHHHHHHHHcccccEEEEEcccccccHHHHHHHHHcccccccccccccccccccEEEEcEEEEEEEEcHHHHHHcccEEEEEEEEEEEcccccccccccccHHHHHHHHHHHHHHccccHHHccEEEEEEcccccccHHHHHHHHHHHcccccccccEEEEccccccccHHHHHHHHHHHHHHHHHHcccccccccccccccccccccccEEEccccccccccccEEEEEEEcccHHHHHHHHHHHccccccccccccccccccccccccccccEEEEEccccHHHHHHHHHHHHHHHHccccccHHHHHHHHHccccccccEEEEEEccHHHHHHHHHHHHcccccccEEEccccccccEEEEEccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHHHccccEEEEEEccHHHHHHHHHHccccHHHHHHHHHHHHHHHHHcccccEEEEEEccHHHHHHHHHcccccEEEEEEEccccEEEEccHHHHHHHHHHHHHcccEEEEEccccccccHHHHHHHHHHHHHHHHcccccccccEEEEccccEEcccccccHHHHHHHHHcHHHHHHHHHHHHHccccEEEEEcccHHHHHHHHHHHHHHcccEEEEEcccccccHHHHHHHHHHHHHHcccccccHHccccccccccccccccccccccccccccccccccccccccccHHccccccccccHHccccHHHHHHHHHHHHHHHHHHHccccccccccccccEEccccccccccccEEEEEEcccccccHHHHHHHHHHHcccccEEEEEEcccccHHHHHHHHHHHHcccccccEEEccccccccccccccHHHHHHHHHHHHHHHHHcccccEEEEEEcccEEcccccccccHHHHHHHHHHHHHHHHcccEEEEEEEEcccccHHHHHHHHHHHccccccEEEEEccEEEEEEEccccccccccccccccccEEEEEEccHHHHHHHHHHHHHccccEEEEEEcccccHHHHHHHHHHHHHcccEEEEEEcccccHHHHHHHHHHHHHccccEEEEEccccccccHHHHccHHHHHHHHHHHHHHHHHHHHHcccccccEEEEHHHHHHHcccccHHHHHHHHHHHHHHHHHHHcccccEEEEEcHHHcccccHHHHHHHHHHHcccccccHHHHHHHHHHHHHcccccEEEEEccHHHHHHHHHHcccccHHHHHHHHHHHccccccccccccccHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHccccHHHccccccHHHHcccHHHHHHHHHHHHHHHcccccHHHHHccccHHHHHHHHHHHcccccccccccccHHHHHHHHHccHHHHccHHHHHHHHHHHHcccccccHHHHHHcccccccccccccccEEEEccccccccccEEEcccccccccccEEccccccccccccccccHHHHHHHHHHHHHHHcccccEEEEEEcHHHHHHHHHHHHHHHccccccEEEEEccccccccccHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHcccccccccccEEEEEcccccccccccccccccccccccEEEEccccHHHHHHHHHHHHHHHHHHHHHHHHccccccccccccccc //