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Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : ACF66807.1
DDBJ      :             pseudouridine synthase, RluA family
Swiss-Prot:RLUA_SALTY   RecName: Full=Ribosomal large subunit pseudouridine synthase A;         EC=5.4.99.-;AltName: Full=rRNA-uridine isomerase A;AltName: Full=rRNA pseudouridylate synthase A;

Homologs  Archaea  5/68 : Bacteria  903/915 : Eukaryota  155/199 : Viruses  0/175   --->[See Alignment]
d.265.1
:219 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   4->219 2i82A PDBj e-109 95.7 %
:RPS:PDB   14->213 2apoA PDBj 2e-25 16.1 %
:RPS:SCOP  15->218 1v9kA  d.265.1.3 * 6e-54 39.3 %
:HMM:SCOP  5->216 1przA_ d.265.1.3 * 8.6e-59 40.9 %
:RPS:PFM   23->168 PF00849 * PseudoU_synth_2 4e-23 40.7 %
:HMM:PFM   22->169 PF00849 * PseudoU_synth_2 1.1e-32 32.4 148/164  
:BLT:SWISS 1->219 RLUA_SALTY e-129 100.0 %
:PROS 60->74|PS01129|PSI_RLU

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF66807.1 GT:GENE ACF66807.1 GT:PRODUCT pseudouridine synthase, RluA family GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION complement(104731..105390) GB:FROM 104731 GB:TO 105390 GB:DIRECTION - GB:PRODUCT pseudouridine synthase, RluA family GB:NOTE identified by match to protein family HMM PF00849 GB:PROTEIN_ID ACF66807.1 GB:DB_XREF GI:194406588 LENGTH 219 SQ:AASEQ MGMENYNPPQEPWLVILYQDEHIMVVNKPSGLLSVPGRLEAHKDSIMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYNVVEFAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEALSLAPRLQLHAEMLTITHPAYGNSMTFKVPADF GT:EXON 1|1-219:0| SW:ID RLUA_SALTY SW:DE RecName: Full=Ribosomal large subunit pseudouridine synthase A; EC=5.4.99.-;AltName: Full=rRNA-uridine isomerase A;AltName: Full=rRNA pseudouridylate synthase A; SW:GN Name=rluA; OrderedLocusNames=STM0095; SW:KW Complete proteome; Isomerase; rRNA processing; tRNA processing. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->219|RLUA_SALTY|e-129|100.0|219/219| GO:SWS:NREP 3 GO:SWS GO:0016853|"GO:isomerase activity"|Isomerase| GO:SWS GO:0006364|"GO:rRNA processing"|rRNA processing| GO:SWS GO:0008033|"GO:tRNA processing"|tRNA processing| PROS 60->74|PS01129|PSI_RLU|PDOC00869| BL:PDB:NREP 1 BL:PDB:REP 4->219|2i82A|e-109|95.7|209/209| RP:PDB:NREP 1 RP:PDB:REP 14->213|2apoA|2e-25|16.1|174/304| RP:PFM:NREP 1 RP:PFM:REP 23->168|PF00849|4e-23|40.7|145/149|PseudoU_synth_2| HM:PFM:NREP 1 HM:PFM:REP 22->169|PF00849|1.1e-32|32.4|148/164|PseudoU_synth_2| GO:PFM:NREP 4 GO:PFM GO:0001522|"GO:pseudouridine synthesis"|PF00849|IPR006145| GO:PFM GO:0003723|"GO:RNA binding"|PF00849|IPR006145| GO:PFM GO:0009451|"GO:RNA modification"|PF00849|IPR006145| GO:PFM GO:0009982|"GO:pseudouridine synthase activity"|PF00849|IPR006145| RP:SCP:NREP 1 RP:SCP:REP 15->218|1v9kA|6e-54|39.3|201/227|d.265.1.3| HM:SCP:REP 5->216|1przA_|8.6e-59|40.9|208/252|d.265.1.3|1/1|Pseudouridine synthase| OP:NHOMO 2969 OP:NHOMOORG 1063 OP:PATTERN --------------------------------------11111------------------------- 2121132322321222223-42112222222222223433112111322111222211111112212222112221112111111221444414-211121223234324-2222222-211114111111111112112211131223233311222322313111222112111112111123311221433-3333333333333322333333333333223333334523333333333333323333-34344343334444444443333333333333333333333333333333333333333333333333322332333222222233332333334232342133141121212223121214333322222333222332322222222222223-323333332232233222222222334433333333333333333333223334222222222221122222222222222122233333222212223222222222222222222222222232224353554343244332224434444442222548142426122411114343444345555952433312222222333333333432332265654454774699999AA77799-A999A2-3233222122244444554444444444-44444444444444444445554444544444444444444445444444431544444444444222522222222233635555455455554445555455534436444444444-33444432222222226777566666557665544444444222222434411111111111122211111-11111221111121111111222222222242 -1--122-1-212331111----111--------------------11-11---111-----22222211232222322321112211-14212221-1112131112E26222223132123123112392-22312312232212112232333132--1333314224-1121324E778232345143A763117 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 219 STR:RPRED 100.0 SQ:SECSTR cTcccTTcccccccHHHHHHTEEEEEEEcccccHHGGGEEEHHHHHHHHHHTTcccEEEcccccTTcEEEEEEEEGTTTEGGGGGGGGTTcccEEEEEEEEEcccccHHHHHHHHHHHcEEHHHHHHEEEEcccEEEEEEEEEcEEEETTEEEEEEEEcTTccHHHHHHHHHHHTTccEEEEEEEEEEEEEEEEETTEEGGGcccHHHHHHHHHHHccc DISOP:02AL 1-1,3-3| PSIPRED cccccccccccccccEEEEcccEEEEEccccEEEEccccccccccHHHHHHHccccEEEEEEccccccEEEEEEccHHHHHHHHHHHHHccEEEEEEEEEEEEEccccEEEEcccccccccccEEEEEcccccccccEEEEEEEccccEEEEEEEEcccccHHHHHHHHHccccEEcccccccHHHcccccccEEEEEEEEEEccccccEEEEEccccc //