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Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : ACF67222.1
DDBJ      :             H(+)/Cl(-) exchange transporter ClcA (ClC-ec1)
Swiss-Prot:CLCA_SALHS   RecName: Full=H(+)/Cl(-) exchange transporter clcA;

Homologs  Archaea  8/68 : Bacteria  275/915 : Eukaryota  2/199 : Viruses  0/175   --->[See Alignment]
f.20.1
:473 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   30->461 1kplB PDBj 0.0 99.3 %
:RPS:PDB   56->460 3ejyA PDBj e-102 50.6 %
:RPS:SCOP  30->460 1kpkA  f.20.1.1 * 2e-80 67.1 %
:HMM:SCOP  12->461 1kpkA_ f.20.1.1 * 5.1e-109 36.4 %
:RPS:PFM   96->436 PF00654 * Voltage_CLC 1e-28 30.6 %
:HMM:PFM   29->96 PF00654 * Voltage_CLC 1.2e-05 17.2 64/355  
:HMM:PFM   89->437 PF00654 * Voltage_CLC 5.6e-93 35.8 346/355  
:HMM:PFM   9->39 PF12607 * DUF3772 5e-05 32.3 31/64  
:BLT:SWISS 1->473 CLCA_SALHS 0.0 100.0 %
:TM
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF67222.1 GT:GENE ACF67222.1 GT:PRODUCT H(+)/Cl(-) exchange transporter ClcA (ClC-ec1) GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION 246397..247818 GB:FROM 246397 GB:TO 247818 GB:DIRECTION + GB:PRODUCT H(+)/Cl(-) exchange transporter ClcA (ClC-ec1) GB:NOTE identified by match to protein family HMM PF00654 GB:PROTEIN_ID ACF67222.1 GB:DB_XREF GI:194407003 LENGTH 473 SQ:AASEQ MKTDTSTFLAQQIVRLRRRDQIRRLMQRDKTPLAILFMAAVVGTLTGLVGVAFEKAVSWVQNMRIGALVQVADHAFLLWPLAFILSALLAMVGYFLVRKFAPEAGGSGIPEIEGALEELRPVRWWRVLPVKFIGGMGTLGAGMVLGREGPTVQIGGNLGRMVLDVFRMRSAEARHTLLATGAAAGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAVFTGVIMSSIVFRIFNGEAPIIEVGKLSDAPVNTLWLYLILGIIFGCVGPVFNSLVLRTQDMFQRFHGGEIKKWVLMGGAIGGLCGILGLIEPEAAGGGFNLIPIAAAGNFSVGLLLFIFIARVVTTLLCFSSGAPGGIFAPMLALGTLLGTAFGMAAAVLFPQYHLEAGTFAIAGMGALMAASVRAPLTGIVLVLEMTDNYQLILPMIITCLGATLLAQFLGGKPLYSTILARTLAKQDAEQAAKNQNAPAGENT GT:EXON 1|1-473:0| SW:ID CLCA_SALHS SW:DE RecName: Full=H(+)/Cl(-) exchange transporter clcA; SW:GN Name=clcA; Synonyms=eriC; OrderedLocusNames=SeHA_C0240; SW:KW Antiport; Cell inner membrane; Cell membrane; Chloride;Complete proteome; Ion transport; Membrane; Transmembrane; Transport. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->473|CLCA_SALHS|0.0|100.0|473/473| GO:SWS:NREP 7 GO:SWS GO:0015297|"GO:antiporter activity"|Antiport| GO:SWS GO:0005886|"GO:plasma membrane"|Cell inner membrane| GO:SWS GO:0005886|"GO:plasma membrane"|Cell membrane| GO:SWS GO:0006811|"GO:ion transport"|Ion transport| GO:SWS GO:0016020|"GO:membrane"|Membrane| GO:SWS GO:0016021|"GO:integral to membrane"|Transmembrane| GO:SWS GO:0006810|"GO:transport"|Transport| TM:NTM 9 TM:REGION 34->56| TM:REGION 72->94| TM:REGION 178->200| TM:REGION 216->238| TM:REGION 253->275| TM:REGION 291->313| TM:REGION 336->358| TM:REGION 390->412| TM:REGION 419->441| SEG 11->29|qqivrlrrrdqirrlmqrd| SEG 39->52|aavvgtltglvgva| SEG 173->195|arhtllatgaaaglsaafnapla| SEG 295->308|ggaigglcgilgli| SEG 358->376|apmlalgtllgtafgmaaa| BL:PDB:NREP 1 BL:PDB:REP 30->461|1kplB|0.0|99.3|432/451| RP:PDB:NREP 1 RP:PDB:REP 56->460|3ejyA|e-102|50.6|405/444| RP:PFM:NREP 1 RP:PFM:REP 96->436|PF00654|1e-28|30.6|337/351|Voltage_CLC| HM:PFM:NREP 3 HM:PFM:REP 29->96|PF00654|1.2e-05|17.2|64/355|Voltage_CLC| HM:PFM:REP 89->437|PF00654|5.6e-93|35.8|346/355|Voltage_CLC| HM:PFM:REP 9->39|PF12607|5e-05|32.3|31/64|DUF3772| GO:PFM:NREP 4 GO:PFM GO:0005247|"GO:voltage-gated chloride channel activity"|PF00654|IPR001807| GO:PFM GO:0006821|"GO:chloride transport"|PF00654|IPR001807| GO:PFM GO:0016020|"GO:membrane"|PF00654|IPR001807| GO:PFM GO:0055085|"GO:transmembrane transport"|PF00654|IPR001807| RP:SCP:NREP 1 RP:SCP:REP 30->460|1kpkA|2e-80|67.1|431/450|f.20.1.1| HM:SCP:REP 12->461|1kpkA_|5.1e-109|36.4|450/450|f.20.1.1|1/1|Clc chloride channel| OP:NHOMO 312 OP:NHOMOORG 285 OP:PATTERN ------11------------------------1----------------11-1-1----1-------- 111-1-------1--------------------111----1-1-------------------------1--1---1111-----1--------1------1------------------------1111111-11-1---------122------12------12-11-2---1-------------------------------------------------------------------------------12-11211213--22211-121-11111111111--1111111111111111111-11111111121111----1-----------1111222-1--1--------1-----1---1111-------------1-1---------------------11-11-1---1----------1---1----------------------1--1-----------------------------------------------1--111---111111-12-1-----1111--------1----------1----------1----1-12-2--1--------11-2--------1----------------------1----11------1-1----------------------1---------111-11-1111111111-1111111111111111111222-1--1211111111111111111111111--111111111111---------11111------------------------------1-----------------111111111-11111111111111--------------1--1--------------1---------------------------1-----1----2- ----------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------1---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 432 STR:RPRED 91.3 SQ:SECSTR #############################cccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTcccHHHHHHHHHHHHHHHHHHHHHHHHHHcGGGccccHHHHHHHHTTcccccHHHHHHHHHHHHHHHTTTTcccccHHHHHHHHHHHHHHHHHHTTcccHHHHHHHHHHHHHHHHHHHHTcHHHHHHHHHHTTccTTccccccHHHHHHHHHHHHHHHHHHccccccccccccccccGGGTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTcHHHHHHHHHHHHHHHHHHHHHcGGGccccTTHHHHHHTTcccHHHHHHHHHHHHHHHHHHHTTTcccccHHHHHHHHHHHHHHHHHHHHHHcGGGTccHHHHHHHHHTTHHHHTcccHHHHHHHHHHHHccGGGHHHHHHHHHHHHHHHHHTTcccHHHHHHHHHHHHHHTTcT############ DISOP:02AL 1-3,450-474| PSIPRED cccccHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccHHHHHHHHccccccccHHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHcccccEEEEcccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHccHHHccccHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHccHHHHcccccccccccccc //