[GTOP] [HELP] [ORGANISMS] [SEARCH] [SUMMARY]
Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : ACF67956.1
DDBJ      :             D-lactate dehydrogenase
Swiss-Prot:LDHD_ECOLI   RecName: Full=D-lactate dehydrogenase;         Short=D-LDH;         EC=1.1.1.28;AltName: Full=Fermentative lactate dehydrogenase;

Homologs  Archaea  67/68 : Bacteria  788/915 : Eukaryota  186/199 : Viruses  1/175   --->[See Alignment]
c.2.1c.23.12c.91.1
:329 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   1->322 1dxyA PDBj 2e-48 33.0 %
:RPS:PDB   2->327 3ba1A PDBj 3e-73 23.1 %
:RPS:SCOP  38->327 1aq2A1  c.91.1.1 * 3e-48 11.6 %
:HMM:SCOP  1->139 2dldA2 c.23.12.1 * 8.5e-49 44.9 %
:HMM:SCOP  101->299 1dxyA1 c.2.1.4 * 7.9e-57 39.4 %
:RPS:PFM   110->263 PF02826 * 2-Hacid_dh_C 9e-39 50.0 %
:HMM:PFM   110->297 PF02826 * 2-Hacid_dh_C 8.9e-56 42.9 175/178  
:BLT:SWISS 1->328 LDHD_ECOLI e-169 93.6 %
:PROS 147->174|PS00065|D_2_HYDROXYACID_DH_1
:PROS 194->216|PS00670|D_2_HYDROXYACID_DH_2
:PROS 223->239|PS00671|D_2_HYDROXYACID_DH_3
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF67956.1 GT:GENE ACF67956.1 GT:PRODUCT D-lactate dehydrogenase GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION 1788132..1789121 GB:FROM 1788132 GB:TO 1789121 GB:DIRECTION + GB:PRODUCT D-lactate dehydrogenase GB:NOTE identified by match to protein family HMM PF00389; match to protein family HMM PF02826 GB:PROTEIN_ID ACF67956.1 GB:DB_XREF GI:194407737 LENGTH 329 SQ:AASEQ MKLAVYSTKQYDKKYLQQVNEAFGFELEFFDFLLTEKTAKTANGCEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLQVVRVPAYSPEAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMHGKTAGVIGTGKIGVAALRILKGFGMRLLAFDPYPSTAALDLGVEYVDLQTLFAESDVISLHCPLTPENYHLLNHAAFDQMKNGVMVINTSRGALIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVIQDDVFRRLSACHNVLFTGHQAFLTAEALISISETTLQNLSQLEKGEACPNALF GT:EXON 1|1-329:0| SW:ID LDHD_ECOLI SW:DE RecName: Full=D-lactate dehydrogenase; Short=D-LDH; EC=1.1.1.28;AltName: Full=Fermentative lactate dehydrogenase; SW:GN Name=ldhA; Synonyms=hslI, htpH; OrderedLocusNames=b1380, JW1375; SW:KW Complete proteome; NAD; Oxidoreductase; Stress response. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->328|LDHD_ECOLI|e-169|93.6|328/329| GO:SWS:NREP 3 GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| GO:SWS GO:0006950|"GO:response to stress"|Stress response| PROS 147->174|PS00065|D_2_HYDROXYACID_DH_1|PDOC00063| PROS 194->216|PS00670|D_2_HYDROXYACID_DH_2|PDOC00063| PROS 223->239|PS00671|D_2_HYDROXYACID_DH_3|PDOC00063| SEG 21->34|eafgfeleffdfll| BL:PDB:NREP 1 BL:PDB:REP 1->322|1dxyA|2e-48|33.0|321/330| RP:PDB:NREP 1 RP:PDB:REP 2->327|3ba1A|3e-73|23.1|308/312| RP:PFM:NREP 1 RP:PFM:REP 110->263|PF02826|9e-39|50.0|154/176|2-Hacid_dh_C| HM:PFM:NREP 1 HM:PFM:REP 110->297|PF02826|8.9e-56|42.9|175/178|2-Hacid_dh_C| GO:PFM:NREP 2 GO:PFM GO:0016616|"GO:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"|PF02826|IPR006140| GO:PFM GO:0048037|"GO:cofactor binding"|PF02826|IPR006140| RP:SCP:NREP 1 RP:SCP:REP 38->327|1aq2A1|3e-48|11.6|267/310|c.91.1.1| HM:SCP:REP 1->139|2dldA2|8.5e-49|44.9|138/0|c.23.12.1|1/1|Formate/glycerate dehydrogenase catalytic domain-like| HM:SCP:REP 101->299|1dxyA1|7.9e-57|39.4|198/199|c.2.1.4|1/1|NAD(P)-binding Rossmann-fold domains| OP:NHOMO 4212 OP:NHOMOORG 1042 OP:PATTERN 22211131111111113222211252223361111111222212121112221233333332112-22 2371722133311243422-231146222224233311882313233-1112665222--323134657613222333113132233344441544---23423444624-----------------1211--12-233551112323124422122111111232223421111112211222113344222333333333333333343543333323347112222132337777777777777786665325544471215544351416972223331----11-----------1----111111-1211111111136167444444424323553222431113324167111122128842-332144334-1--156CB93235978444444443445-6766755AC85-AAA5668777BE9643133767787342222222234431322-----------------------------222523475498AA9962444477A966665695D78B8-46644446593847A54212--12112222244312133321--23112222222222346333323242222222222222222222212332225565633333444444454444444454441-12234------45544444445465644-44456554544644444446B756324444444444444444465544444216666666666661-2311111434324465222334-33233222334333622373665648A8466873655112123111323335455444555333333333411112213222233--------11-------1---2------11------3243223222232 ----372-21--35279B78777B9A75655667775A78979767855ABEFG58876545D4623314335355424479978A33-7E69674A9A8616554-384CA98AA622-34426E2D4AW7-66A143294253-333151-54B57A35524633E58822753754t45437G9FK79955E8DB2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- STR:NPRED 328 STR:RPRED 99.7 SQ:SECSTR cccEEEEcccccHHHHHHHHHHcEEEEGGGcccHHHHHHHHTTTEEEEEEcccccccHHHHHHcHcTTccEEEEcccccTTccHHHHHHHTcEEEccccTTHHHHHHHHHHHHHHHHTTHHHHHHHHHTTGGGGccccccccTTccEEEEcccHHHHHHHHHHHTTTccEEEEcccccTTcccccEEEccHHHHHHTccEEEEcccccGGGTTcccHHHHHHHcTTcEEEEcccGGGccHHHHHHHHHHTcccEEEEcccTTTHHHHHHHHHHccccTcccGGGGGcTTEEEccccTTccHHHHHHHHHHHHHHHHHHHHTccccccE# PSIPRED cEEEEEEEccccHHHHHHHHHHcccEEEEccccccHHHHHHHccccEEEEEccccccHHHHHHccccccEEEEEcccccccccHHHHHHcccEEEEcccccHHHHHHHHHHHHHHHHHcHHHHHHHHHcccccccccccccccccEEEEEEccHHHHHHHHHHHHcccEEEEEccccccHHHHcccEEccHHHHHHHccEEEEEccccHHHHccccHHHHHHccccEEEEEccccccccHHHHHHHHHcccEEEEEEccccccccccccccccccccccccHHHHccccEEEccccccccHHHHHHHHHHHHHHHHHHHcccccccccc //