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Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : ACF69484.1
DDBJ      :             macrolide export ATP-binding/permease protein MacB
Swiss-Prot:MACB_SALTI   RecName: Full=Macrolide export ATP-binding/permease protein macB;         EC=3.6.3.-;

Homologs  Archaea  68/68 : Bacteria  906/915 : Eukaryota  186/199 : Viruses  0/175   --->[See Alignment]
c.37.1
:648 amino acids
:PSIPRED
:DISOPRED
:BLT:PDB   4->232 1l2tB PDBj 1e-51 46.2 %
:BLT:PDB   298->518 3ftjA PDBj 5e-33 36.8 %
:RPS:PDB   4->229 3b5jA PDBj 2e-47 28.7 %
:RPS:SCOP  4->229 1b0uA  c.37.1.12 * 1e-42 33.8 %
:HMM:SCOP  7->222 1ii8.1 c.37.1.12 * 2.7e-71 43.6 %
:RPS:PFM   48->172 PF00005 * ABC_tran 2e-11 37.9 %
:RPS:PFM   482->639 PF02687 * FtsX 5e-20 39.4 %
:HMM:PFM   470->641 PF02687 * FtsX 4.7e-29 27.8 169/175  
:HMM:PFM   48->172 PF00005 * ABC_tran 1.4e-25 39.7 116/118  
:HMM:PFM   142->217 PF02463 * SMC_N 0.00024 21.3 75/220  
:HMM:PFM   23->55 PF03193 * DUF258 1.5e-05 34.4 32/161  
:BLT:SWISS 1->648 MACB_SALTI 0.0 99.4 %
:PROS 145->159|PS00211|ABC_TRANSPORTER_1
:TM
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF69484.1 GT:GENE ACF69484.1 GT:PRODUCT macrolide export ATP-binding/permease protein MacB GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION 1024279..1026225 GB:FROM 1024279 GB:TO 1026225 GB:DIRECTION + GB:PRODUCT macrolide export ATP-binding/permease protein MacB GB:NOTE identified by match to protein family HMM PF00005; match to protein family HMM PF02687 GB:PROTEIN_ID ACF69484.1 GB:DB_XREF GI:194409265 LENGTH 648 SQ:AASEQ MTALLELRNVSRSYPSGEEQVAVLKDISLQIHAGEMVAIVGVSGSGKSTLMNILGCLDKPTSGTYRVAGRDVSTLDPDALAQLRREHFGFIFQRYHLLSHLTAAQNVEIPAVYAGIERKKRQARARELLLRLGLSDRVDYPPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILRQLRDRGHTVIIVTHDPLIAAQAERIIEIHDGKIVHNPPAEEKKREQGVDAAVVNTAPGWRQFASSFREALSMAWLAMAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRAMGTNTIDIHPGKDFGDDNPQYRQALKYDDLVAIQKQLWVNSATPSVSKSLRLRYGNIDIAVNANGVSGDYFNVYGMSFREGNTFNDVQQQDRAQVVVLDANTRRQLFPNKANVVGEVVLVGNMPVIVIGVAEEKPSMYGNSNLLQVWLPYSTMSDRIMGQSWLNSITVRVKDGVDSDQAEQQLTRLLTLRHGKKDFFTWNMDSVLKTAEKTTYTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGISLSMFIAFMLQLFLPGWEIGFSLTALASAFLCSTFTGILFGWLPARNAARLDPVDALARE GT:EXON 1|1-648:0| SW:ID MACB_SALTI SW:DE RecName: Full=Macrolide export ATP-binding/permease protein macB; EC=3.6.3.-; SW:GN Name=macB; OrderedLocusNames=STY0938, t1991; SW:KW Antibiotic resistance; ATP-binding; Cell inner membrane;Cell membrane; Complete proteome; Hydrolase; Membrane;Nucleotide-binding; Transmembrane; Transport. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->648|MACB_SALTI|0.0|99.4|648/648| GO:SWS:NREP 9 GO:SWS GO:0046677|"GO:response to antibiotic"|Antibiotic resistance| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005886|"GO:plasma membrane"|Cell inner membrane| GO:SWS GO:0005886|"GO:plasma membrane"|Cell membrane| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| GO:SWS GO:0016020|"GO:membrane"|Membrane| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0016021|"GO:integral to membrane"|Transmembrane| GO:SWS GO:0006810|"GO:transport"|Transport| PROS 145->159|PS00211|ABC_TRANSPORTER_1|PDOC00185| TM:NTM 4 TM:REGION 273->295| TM:REGION 524->546| TM:REGION 573->595| TM:REGION 610->632| SEG 117->134|erkkrqararelllrlgl| SEG 278->296|giiigiasvvsivvvgdaa| SEG 392->405|dvqqqdraqvvvld| BL:PDB:NREP 2 BL:PDB:REP 4->232|1l2tB|1e-51|46.2|225/232| BL:PDB:REP 298->518|3ftjA|5e-33|36.8|212/214| RP:PDB:NREP 1 RP:PDB:REP 4->229|3b5jA|2e-47|28.7|223/243| RP:PFM:NREP 2 RP:PFM:REP 48->172|PF00005|2e-11|37.9|116/123|ABC_tran| RP:PFM:REP 482->639|PF02687|5e-20|39.4|155/177|FtsX| HM:PFM:NREP 4 HM:PFM:REP 470->641|PF02687|4.7e-29|27.8|169/175|FtsX| HM:PFM:REP 48->172|PF00005|1.4e-25|39.7|116/118|ABC_tran| HM:PFM:REP 142->217|PF02463|0.00024|21.3|75/220|SMC_N| HM:PFM:REP 23->55|PF03193|1.5e-05|34.4|32/161|DUF258| GO:PFM:NREP 3 GO:PFM GO:0005524|"GO:ATP binding"|PF00005|IPR003439| GO:PFM GO:0016887|"GO:ATPase activity"|PF00005|IPR003439| GO:PFM GO:0016020|"GO:membrane"|PF02687|IPR003838| RP:SCP:NREP 1 RP:SCP:REP 4->229|1b0uA|1e-42|33.8|222/258|c.37.1.12| HM:SCP:REP 7->222|1ii8.1|2.7e-71|43.6|211/370|c.37.1.12|1/1|P-loop containing nucleoside triphosphate hydrolases| OP:NHOMO 35413 OP:NHOMOORG 1160 OP:PATTERN MME9JGCAQPQOQMRGZBJJHKKQjJMTdPTPE97899FGIFCSZFTWKOrlc7IQLNOFKACBO155 Tj*E*TRVaaeISJNLMKK-KU88R*KKKKKKjbbdi***OrL*e*iWfbWLsnlKMS33nohXvhn***UXSSSxTVSLmTh97A7AMMJH1ICCB--BDNDEITDTPJ44444448987777DOIELLHDNIOMgjktt996lUdYXjVVYTXOQJEHFJFXRVeqtlKEKAEEBDJCEECTQRMLbW7OSituwuvr**q**wqu**mlljk*y*VQavmWdifgbbe**RZbdYdYXZZaaZZYLTOPOgVNRqsPJLNQigHHlpPPJRbVWTUdbcbdXhjlifgdeeeejcefWVUUSVVUWVVUUnYZRRSaZaXb*huxuuuuxwtVpQUyttPUVO*UYWUwUYRE**baTVYOKUZSZTGIQYIWTQQHCCE9BXR***OId*zv*qx*x**s*uvv*-eg*aY*dw**P7**************FCLs*********HGHHHHHHkOREIUTy22223444333323445243232246252GDCEADq**s*******momoh****vsvvXw***wy*t9GllgoYjfj*s****PbeKLGIfQDDCCDCDONNWgXRf*DTQgfKagUSdESWSRLQZQVcZWersVoDECGDCBCC9D99ABBBBABFL7CCMLdYlHgNVCNDqIJMMKINRLLKLLMPLOOP5-AEMJH2--111rj**Prmfjilgnkmdf-ifegigmihjjmicdeccc*****SQOZbYaYZZZYYWYZYaY*aXXZaYeK2tuvvzyusvxzx23ADEFCEFJKKKNDxe*OONQNOEDEBCJJNUKLNLLBK9EKdWrojrn***kuxnoW***999788989CRcZibccccjnkqmMNKGJGHEGF978742HKIIA9DF45443444m8OA88A6-554578798747B8A5444LVXJHWhXYUBdK ----CEE-SG36BHD85955AA6E6E63344447476978776433539BAFID77C57342332-1---31-1221-2224341231-BE558335337326882-BGGhEKISKVHDIEFKIhd9kB**Z2cMUFFD8YDDUL9IDBBVAA*ENHGdCO*BSEI6MHI*HRIB8955q5644BQBDh4WJ57ePSP6 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- DISOP:02AL 1-1,227-238,321-323,437-450,648-649| PSIPRED cccEEEEEEEEEEEccccEEEEEEcccEEEEccccEEEEEccccccHHHHHHHHHccccccccEEEEccEEHHcccHHHHHHHHHHHccEEEEcccccccccHHHHHHHHHHHccccHHHHHHHHHHHHHHccHHHHHHccHHHccccHHHHHHHHHHHcccccEEEEEcccccccHHHHHHHHHHHHHHHHcccEEEEEcccHHHHHHccEEEEEEccEEEEEccHHHcccccccccccccccHHHHHHHHHHHHHHHHHHHHHHHcccccHHHccccccccccEEEEEEEcccccHHHHHHHHHHcccEEEEEcccccccccccccccccHHHHHHHHHccccEEEEEEcccEEEEEEccEEEEEEEEcccHHHHHHHcccHHHcccccHHHHHHHccEEEEcHHHHHHHccccccccccEEEEccEEEEEEEEEcccccccccccccEEEEEHHHHHHHHHccccccEEEEEEEccccHHHHHHHHHHHHHHHcccccEEEEcHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccEEccHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccEEEEccHHHHHHHHHHHHHHHHHHcHHHHHHHHccHHHHHHcc //