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Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : ACF69898.1
DDBJ      :             regulatory protein ada
Swiss-Prot:ADA_SALTY    RecName: Full=Regulatory protein ada;AltName: Full=Regulatory protein of adaptative response;Contains:  RecName: Full=Methylated-DNA--protein-cysteine methyltransferase;           EC=2.1.1.63;  AltName: Full=O-6-methylguanine-DNA alkyltransferase;

Homologs  Archaea  17/68 : Bacteria  724/915 : Eukaryota  96/199 : Viruses  1/175   --->[See Alignment]
a.4.1a.4.2c.55.7g.48.1
:352 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   1->128 1wpkA PDBj 2e-51 76.4 %
:BLT:PDB   186->349 1sfeA PDBj 3e-61 68.3 %
:RPS:PDB   1->91 1adnA PDBj 3e-29 68.1 %
:RPS:PDB   84->190 1bl0A PDBj 6e-12 19.6 %
:RPS:PDB   188->350 1eh6A PDBj 4e-41 31.2 %
:RPS:SCOP  1->91 1adnA  g.48.1.1 * 1e-29 68.1 %
:RPS:SCOP  85->128 1bl0A1  a.4.1.8 * 9e-09 29.5 %
:RPS:SCOP  186->266 1sfeA2  c.55.7.1 * 2e-15 63.0 %
:RPS:SCOP  268->350 1eh6A1  a.4.2.1 * 1e-31 42.2 %
:HMM:SCOP  1->91 1eyfA_ g.48.1.1 * 2.1e-30 49.5 %
:HMM:SCOP  82->133 1d5yA1 a.4.1.8 * 6.4e-10 40.4 %
:HMM:SCOP  186->266 1sfeA2 c.55.7.1 * 1.6e-19 42.0 %
:HMM:SCOP  267->350 1sfeA1 a.4.2.1 * 1e-32 52.4 %
:RPS:PFM   10->74 PF02805 * Ada_Zn_binding 3e-15 56.9 %
:RPS:PFM   190->264 PF02870 * Methyltransf_1N 2e-09 45.8 %
:RPS:PFM   270->347 PF01035 * DNA_binding_1 5e-19 48.7 %
:HMM:PFM   9->74 PF02805 * Ada_Zn_binding 1.3e-33 60.6 66/66  
:HMM:PFM   268->348 PF01035 * DNA_binding_1 5.4e-33 50.6 81/85  
:HMM:PFM   188->265 PF02870 * Methyltransf_1N 2.5e-22 35.5 76/77  
:HMM:PFM   97->130 PF00165 * HTH_AraC 1.6e-10 41.2 34/42  
:HMM:PFM   139->181 PF00165 * HTH_AraC 4.7e-06 28.6 42/42  
:BLT:SWISS 1->352 ADA_SALTY 0.0 99.1 %
:PROS 85->127|PS00041|HTH_ARAC_FAMILY_1
:PROS 135->176|PS00041|HTH_ARAC_FAMILY_1
:PROS 318->324|PS00374|MGMT
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF69898.1 GT:GENE ACF69898.1 GT:PRODUCT regulatory protein ada GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION complement(2410697..2411755) GB:FROM 2410697 GB:TO 2411755 GB:DIRECTION - GB:PRODUCT regulatory protein ada GB:NOTE identified by match to protein family HMM PF00165; match to protein family HMM PF01035; match to protein family HMM PF02805; match to protein family HMM PF02870; match to protein family HMM TIGR00589 GB:PROTEIN_ID ACF69898.1 GB:DB_XREF GI:194409679 LENGTH 352 SQ:AASEQ MKKALLTDDECWLRVQARDASADGRFVFAVRTTGVFCRPSCRSKRALRKNVRFFANAQQALDAGFRPCKRCQPDNARAQQRRLDKIACACRLLEQETPVTLASLAQAVAMSPFHLHRLFKASTGMTPKGWQQAWRARRLREALAKGEPITAAIYRAGFPDSSSYYRHADQTLGMTAKQFRKGGDNVSVRYALTDWVYGRCLVAESERGICAILPGDSDDALLAELHTLFPAARHEPADALFQQRVRQVVAAINTRDVLLSLPLDIQGTAFQQQVWQALCAIPCGETVSYQQLAATIGKPTAVRAVASACGANKLAMVIPCHRVVRRDGALSGYRWGVRRKAQLLKREAQKEE GT:EXON 1|1-352:0| SW:ID ADA_SALTY SW:DE RecName: Full=Regulatory protein ada;AltName: Full=Regulatory protein of adaptative response;Contains: RecName: Full=Methylated-DNA--protein-cysteine methyltransferase; EC=2.1.1.63; AltName: Full=O-6-methylguanine-DNA alkyltransferase; SW:GN Name=ada; OrderedLocusNames=STM2265; SW:KW Activator; Complete proteome; DNA damage; DNA repair; DNA-binding;Metal-binding; Methyltransferase; Transcription;Transcription regulation; Transferase; Zinc. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->352|ADA_SALTY|0.0|99.1|352/353| GO:SWS:NREP 8 GO:SWS GO:0006974|"GO:response to DNA damage stimulus"|DNA damage| GO:SWS GO:0006281|"GO:DNA repair"|DNA repair| GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0008168|"GO:methyltransferase activity"|Methyltransferase| GO:SWS GO:0006350|"GO:transcription"|Transcription| GO:SWS GO:0045449|"GO:regulation of transcription"|Transcription regulation| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 85->127|PS00041|HTH_ARAC_FAMILY_1|PDOC00040| PROS 135->176|PS00041|HTH_ARAC_FAMILY_1|PDOC00040| PROS 318->324|PS00374|MGMT|PDOC00320| SEG 130->144|wqqawrarrlreala| BL:PDB:NREP 2 BL:PDB:REP 1->128|1wpkA|2e-51|76.4|127/145| BL:PDB:REP 186->349|1sfeA|3e-61|68.3|164/165| RP:PDB:NREP 3 RP:PDB:REP 1->91|1adnA|3e-29|68.1|91/92| RP:PDB:REP 84->190|1bl0A|6e-12|19.6|107/116| RP:PDB:REP 188->350|1eh6A|4e-41|31.2|160/168| RP:PFM:NREP 3 RP:PFM:REP 10->74|PF02805|3e-15|56.9|65/66|Ada_Zn_binding| RP:PFM:REP 190->264|PF02870|2e-09|45.8|72/75|Methyltransf_1N| RP:PFM:REP 270->347|PF01035|5e-19|48.7|78/85|DNA_binding_1| HM:PFM:NREP 5 HM:PFM:REP 9->74|PF02805|1.3e-33|60.6|66/66|Ada_Zn_binding| HM:PFM:REP 268->348|PF01035|5.4e-33|50.6|81/85|DNA_binding_1| HM:PFM:REP 188->265|PF02870|2.5e-22|35.5|76/77|Methyltransf_1N| HM:PFM:REP 97->130|PF00165|1.6e-10|41.2|34/42|HTH_AraC| HM:PFM:REP 139->181|PF00165|4.7e-06|28.6|42/42|HTH_AraC| GO:PFM:NREP 9 GO:PFM GO:0003677|"GO:DNA binding"|PF02805|IPR004026| GO:PFM GO:0006281|"GO:DNA repair"|PF02805|IPR004026| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF02805|IPR004026| GO:PFM GO:0008168|"GO:methyltransferase activity"|PF02805|IPR004026| GO:PFM GO:0008270|"GO:zinc ion binding"|PF02805|IPR004026| GO:PFM GO:0003908|"GO:methylated-DNA-[protein]-cysteine S-methyltransferase activity"|PF02870|IPR008332| GO:PFM GO:0006281|"GO:DNA repair"|PF02870|IPR008332| GO:PFM GO:0003824|"GO:catalytic activity"|PF01035|IPR014048| GO:PFM GO:0006281|"GO:DNA repair"|PF01035|IPR014048| RP:SCP:NREP 4 RP:SCP:REP 1->91|1adnA|1e-29|68.1|91/92|g.48.1.1| RP:SCP:REP 85->128|1bl0A1|9e-09|29.5|44/54|a.4.1.8| RP:SCP:REP 186->266|1sfeA2|2e-15|63.0|81/81|c.55.7.1| RP:SCP:REP 268->350|1eh6A1|1e-31|42.2|83/90|a.4.2.1| HM:SCP:REP 1->91|1eyfA_|2.1e-30|49.5|91/0|g.48.1.1|1/1|Ada DNA repair protein, N-terminal domain (N-Ada 10)| HM:SCP:REP 82->133|1d5yA1|6.4e-10|40.4|52/54|a.4.1.8|1/2|Homeodomain-like| HM:SCP:REP 186->266|1sfeA2|1.6e-19|42.0|81/0|c.55.7.1|1/1|Methylated DNA-protein cysteine methyltransferase domain| HM:SCP:REP 267->350|1sfeA1|1e-32|52.4|84/0|a.4.2.1|1/1|Methylated DNA-protein cysteine methyltransferase, C-terminal domain| OP:NHOMO 1400 OP:NHOMOORG 838 OP:PATTERN ------1-1111111-1---------------11------------1--1111--------------1 13412-111111-122222-2311132222213232222212122223111-3222-3--212121354321111111-1211-----111111111--112111412-3--------------2--111---1--111111113-2--111---11---------2111------------------1--11333333334133434333332333311151334344434311111111111111111111211-11-12-11111111111112-2111111111111111111111-------------1111--11111131111111131111211-11-2111----11332-1111111111-111115443-1111214241113333322222212223-11111111132-22242212223311211113111122311111111322-1113------------1-11112---12-----111311333234344432223244332122228334445114451222312333233311124211111111312113-1-1---2-1--1-111-11-1122123211211111111111111111112---133431211212212332332232221222221---21-1------22221322222222212-222222222222222222232334112222222222222222222222222--222222222222--12121112221-1322111111111111111222121211122333233332222211111111111111111322222-222222121221111111--11111111--------111-------1----------1-1------1--11111132 ----11--21---2---111111222111111111111-1111---11231-111111----122-1--11121211111122212------------------------1----1----1-1112-1-241-111-1-12-1-1-11--1----1--1----11--1--51211----------1--------1---- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- STR:NPRED 350 STR:RPRED 99.4 SQ:SECSTR cccccccHHHHHHHHHHccccccTTcEEEETTTTEEEcccccccccccccEEEEccHHHHHHHTccEEcccccccccTTTcccccccccccHHHTTcccccHHHHHHccccHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHcccHHHHHHHTTcccHHHHHHHHEEEEETTEEEEEccccccEcEEEEEccTTccEEEEEETTEEEEEEEccccccccccccccHHHHHHHHHHHHHHHHHHcGGGGGGccccccccHHHHcccHHHHHHHHHHHHccTTccEEHHHHHHHTTcTTcHHHHHHHTTcccccTTccGGGEEcTTccccccTTcHHHHHHHHHHTTcc## DISOP:02AL 1-3,348-348,350-353| PSIPRED cccccccHHHHHHHHHHcccccccEEEEEEEccccccccccccccccHHHHHccccHHHHHHccccHHHccccccccccccHHHHHHHHHHHccccccccHHHHHHHHcccHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHccccHHHHHHHHccccHHHHHHHHHHHHcccHHHHHHHcccccccccccccccccccEEEcccEEEEEEEcccHHHHHHHHHHHccccccccccHHHHHHHHHHHHHHccccccccccccccccHHHHHHHHHHHccccccEEcHHHHHHHccccccHHHHHHHHHccccEEEccccEEEccccccccccccHHHHHHHHHHcccccc //