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Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : clpA
DDBJ      :clpA         ATP-dependent Clp protease ATP-binding subunit ClpA
Swiss-Prot:CLPA_ECOLI   RecName: Full=ATP-dependent Clp protease ATP-binding subunit clpA;

Homologs  Archaea  6/68 : Bacteria  892/915 : Eukaryota  182/199 : Viruses  0/175   --->[See Alignment]
a.174.1c.37.1
:758 amino acids
:PSIPRED
:DISOPRED
:BLT:PDB   1->755 1ksfX PDBj 0.0 97.8 %
:RPS:PDB   173->296 3bbnG PDBj 6e-32 19.4 %
:RPS:PDB   279->658 1bpoA PDBj 2e-46 9.8 %
:RPS:PDB   629->722 1av6A PDBj 1e-04 8.6 %
:RPS:SCOP  1->142 1k6kA  a.174.1.1 * 6e-39 98.6 %
:RPS:SCOP  168->436 1ksfX2  c.37.1.20 * e-115 99.2 %
:RPS:SCOP  437->755 1ksfX3  c.37.1.20 * 8e-54 94.8 %
:HMM:SCOP  1->142 1k6kA_ a.174.1.1 * 5.6e-60 62.0 %
:HMM:SCOP  166->426 1qvrA2 c.37.1.20 * 7.8e-71 37.1 %
:HMM:SCOP  437->755 1ksfX3 c.37.1.20 * 1.1e-84 34.8 %
:RPS:PFM   17->59 PF02861 * Clp_N 3e-05 53.5 %
:RPS:PFM   211->344 PF00004 * AAA 7e-09 38.6 %
:RPS:PFM   487->644 PF07724 * AAA_2 3e-34 51.4 %
:RPS:PFM   656->733 PF10431 * ClpB_D2-small 1e-09 35.9 %
:HMM:PFM   486->647 PF07724 * AAA_2 1.5e-49 46.7 150/171  
:HMM:PFM   653->737 PF10431 * ClpB_D2-small 1.6e-28 44.7 85/89  
:HMM:PFM   211->343 PF00004 * AAA 4e-16 32.8 116/130  
:HMM:PFM   13->62 PF02861 * Clp_N 3.6e-17 40.0 50/53  
:BLT:SWISS 1->758 CLPA_ECOLI 0.0 97.2 %
:PROS 302->314|PS00870|CLPAB_1
:PROS 518->536|PS00871|CLPAB_2

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF69477.1 GT:GENE clpA GT:PRODUCT ATP-dependent Clp protease ATP-binding subunit ClpA GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION 1027251..1029527 GB:FROM 1027251 GB:TO 1029527 GB:DIRECTION + GB:GENE clpA GB:PRODUCT ATP-dependent Clp protease ATP-binding subunit ClpA GB:NOTE identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR02639 GB:PROTEIN_ID ACF69477.1 GB:DB_XREF GI:194409258 GB:GENE:GENE clpA LENGTH 758 SQ:AASEQ MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRSEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDIVNFISHGTRKDEPSQSSDLGNQPTGDEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSVEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDNAIEALTEAIKMSRAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNLLLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMGEIKKVFTPEFRNRLDNIIWFDHLSGEVIHQVVDKFIVELQAQLDQKGVSLEVSQEARDWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNALTYDFQSAQKHKPEAAH GT:EXON 1|1-758:0| SW:ID CLPA_ECOLI SW:DE RecName: Full=ATP-dependent Clp protease ATP-binding subunit clpA; SW:GN Name=clpA; Synonyms=lopD; OrderedLocusNames=b0882, JW0866; SW:KW 3D-structure; ATP-binding; Chaperone; Complete proteome;Direct protein sequencing; Nucleotide-binding; Repeat. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->758|CLPA_ECOLI|0.0|97.2|758/758| GO:SWS:NREP 2 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| PROS 302->314|PS00870|CLPAB_1|PDOC00679| PROS 518->536|PS00871|CLPAB_2|PDOC00679| BL:PDB:NREP 1 BL:PDB:REP 1->755|1ksfX|0.0|97.8|714/714| RP:PDB:NREP 3 RP:PDB:REP 173->296|3bbnG|6e-32|19.4|124/154| RP:PDB:REP 279->658|1bpoA|2e-46|9.8|379/487| RP:PDB:REP 629->722|1av6A|1e-04|8.6|93/289| RP:PFM:NREP 4 RP:PFM:REP 17->59|PF02861|3e-05|53.5|43/52|Clp_N| RP:PFM:REP 211->344|PF00004|7e-09|38.6|114/123|AAA| RP:PFM:REP 487->644|PF07724|3e-34|51.4|146/160|AAA_2| RP:PFM:REP 656->733|PF10431|1e-09|35.9|78/90|ClpB_D2-small| HM:PFM:NREP 4 HM:PFM:REP 486->647|PF07724|1.5e-49|46.7|150/171|AAA_2| HM:PFM:REP 653->737|PF10431|1.6e-28|44.7|85/89|ClpB_D2-small| HM:PFM:REP 211->343|PF00004|4e-16|32.8|116/130|AAA| HM:PFM:REP 13->62|PF02861|3.6e-17|40.0|50/53|Clp_N| GO:PFM:NREP 4 GO:PFM GO:0005515|"GO:protein binding"|PF02861|IPR004176| GO:PFM GO:0019538|"GO:protein metabolic process"|PF02861|IPR004176| GO:PFM GO:0005524|"GO:ATP binding"|PF00004|IPR003959| GO:PFM GO:0005524|"GO:ATP binding"|PF07724|IPR013093| RP:SCP:NREP 3 RP:SCP:REP 1->142|1k6kA|6e-39|98.6|142/142|a.174.1.1| RP:SCP:REP 168->436|1ksfX2|e-115|99.2|266/266|c.37.1.20| RP:SCP:REP 437->755|1ksfX3|8e-54|94.8|306/306|c.37.1.20| HM:SCP:REP 1->142|1k6kA_|5.6e-60|62.0|142/0|a.174.1.1|1/1|Double Clp-N motif| HM:SCP:REP 166->426|1qvrA2|7.8e-71|37.1|259/0|c.37.1.20|1/2|P-loop containing nucleoside triphosphate hydrolases| HM:SCP:REP 437->755|1ksfX3|1.1e-84|34.8|319/319|c.37.1.20|2/2|P-loop containing nucleoside triphosphate hydrolases| OP:NHOMO 2923 OP:NHOMOORG 1080 OP:PATTERN ----------------------------------1-----1--11--1-1------------------ 2372422244222222222-22222222222222223444243232222222323232224322236443223223222224322222432312223--2232224232222222222222222433333333333444452226234334442233333333333454563333333333333332222123222222222222222222222222233322223333432143333333443334432222333334333334433444543533333363333344333333333333333333334333543333333332243222222223222444222233421222222212211111112213332222422222233342222222322222222223-24224432232233332342222232222234323322233333333333322222222222222--11111121111112122-2223233324755356557777566888837634555322323323223322422232322322222222222233222222232332222111122131335398222112222222222222222222122223334434222322222232222222222331-22222------24233232333244443-3123223325343222223433336532433432333333332422222232-3777777477761122222222222236331111211111111113333333222428888344454344343311111111124343333333444322324224452222222233333322222212331----1-11111111111111--1112223332233242 3311223-73212222422222222222232222222222322222222322222222223223222222222232213222122222-2824223222223134412A321111-11111111311313B1-21211112111-111--11121-1121--1212-------3145B5t44454A8AF38A4653423 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- DISOP:02AL 65-79,141-167,296-300,745-759| PSIPRED cccHHHHHHHHHHHHHHHHcccccccHHHHHHHHHccHHHHHHHHHccccHHHHHHHHHHHHHHcccccccccccccccccHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHccccHHHHHHHHccccHHHHHHHHHHcccccccHHHHHHHccccccccccccccHHHHHccHHHHHHHccccccccHHHHHHHHHHHccccccccEEEEccccccHHHHHHHHHHHHHcccccHHHcccEEEEEEHHHHHHHcccccHHHHHHHHHHHHHHHcccEEEEEEcHHHHccccccccccHHHHHHHHHHHccccEEEEEEccHHHHHHHHHccHHHHHcccEEEcccccHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHccccccccHHHHHHHHHHHcccccHHHcHHHHHcccHHHHHHHHHHccHHHHHHHHHHHHHHHHHcccccccccEEEEEccccHHHHHHHHHHHHHHccccEEEEEcccHHHHHHHHHHHccccccccccHHHHHHHHHHHccccEEEEEcHHHccHHHHHHHHHHHHccccccccccEEccccEEEEEcccccHHHHHHcccccccHHHHHHHHHHHHHHccHHHHccccEEEEcccccHHHHHHHHHHHHHHHHHHHHHcccEEEEcHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHcccccccEEEEEEEccccEEEEEEcccccccccccc //