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Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : eda
DDBJ      :eda          2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase
Swiss-Prot:ALKH_SHIFL   RecName: Full=KHG/KDPG aldolase;Includes:  RecName: Full=4-hydroxy-2-oxoglutarate aldolase;           EC=4.1.3.16;  AltName: Full=2-keto-4-hydroxyglutarate aldolase;           Short=KHG-aldolase;Includes:  RecName: Full=2-dehydro-3-deoxy-phosphogluconate aldolase;           EC=4.1.2.14;  AltName: Full=Phospho-2-dehydro-3-deoxygluconate aldolase;  AltName: Full=Phospho-2-keto-3-deoxygluconate aldolase;  AltName: Full=2-keto-3-deoxy-6-phosphogluconate aldolase;           Short=KDPG-aldolase;

Homologs  Archaea  5/68 : Bacteria  483/915 : Eukaryota  14/199 : Viruses  0/175   --->[See Alignment]
c.1.10
:213 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   1->212 1euaA PDBj e-115 97.2 %
:RPS:PDB   18->212 3ceuA PDBj 4e-13 12.4 %
:RPS:SCOP  1->212 1euaA  c.1.10.1 * 2e-57 97.2 %
:HMM:SCOP  1->213 1euaA_ c.1.10.1 * 3.9e-68 47.4 %
:RPS:PFM   11->200 PF01081 * Aldolase 2e-41 52.9 %
:HMM:PFM   9->203 PF01081 * Aldolase 7.9e-96 67.7 195/196  
:BLT:SWISS 1->212 ALKH_SHIFL e-115 97.2 %
:PROS 40->49|PS00159|ALDOLASE_KDPG_KHG_1
:PROS 128->141|PS00160|ALDOLASE_KDPG_KHG_2

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF67877.1 GT:GENE eda GT:PRODUCT 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION complement(2025963..2026604) GB:FROM 2025963 GB:TO 2026604 GB:DIRECTION - GB:GENE eda GB:PRODUCT 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase GB:NOTE identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182 GB:PROTEIN_ID ACF67877.1 GB:DB_XREF GI:194407658 GB:GENE:GENE eda LENGTH 213 SQ:AASEQ MKNWKTSAEAILTTGPVVPVIVVNKLEHAVPMAKALVAGGVRVLEVTLRTACAMDAIRAIAKEVPEAIVGAGTVLNPQQLAEVTEAGAQFAISPGLTEPLLKAATAGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEANGGTKALQAIAGPFSQVRFCPTGGISPANYRDYLALKSVLCIGGSWLVPADALEAGDYDRITKLAREAVEGAKQ GT:EXON 1|1-213:0| SW:ID ALKH_SHIFL SW:DE RecName: Full=KHG/KDPG aldolase;Includes: RecName: Full=4-hydroxy-2-oxoglutarate aldolase; EC=4.1.3.16; AltName: Full=2-keto-4-hydroxyglutarate aldolase; Short=KHG-aldolase;Includes: RecName: Full=2-dehydro-3-deoxy-phosphogluconate aldolase; EC=4.1.2.14; AltName: Full=Phospho-2-dehydro-3-deoxygluconate aldolase; AltName: Full=Phospho-2-keto-3-deoxygluconate aldolase; AltName: Full=2-keto-3-deoxy-6-phosphogluconate aldolase; Short=KDPG-aldolase; SW:GN Name=eda; OrderedLocusNames=SF1860, S1926; SW:KW Complete proteome; Cytoplasm; Lyase; Multifunctional enzyme;Schiff base. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->212|ALKH_SHIFL|e-115|97.2|212/213| GO:SWS:NREP 3 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016829|"GO:lyase activity"|Lyase| GO:SWS GO:0003824|"GO:catalytic activity"|Multifunctional enzyme| PROS 40->49|PS00159|ALDOLASE_KDPG_KHG_1|PDOC00144| PROS 128->141|PS00160|ALDOLASE_KDPG_KHG_2|PDOC00144| BL:PDB:NREP 1 BL:PDB:REP 1->212|1euaA|e-115|97.2|212/213| RP:PDB:NREP 1 RP:PDB:REP 18->212|3ceuA|4e-13|12.4|178/193| RP:PFM:NREP 1 RP:PFM:REP 11->200|PF01081|2e-41|52.9|189/194|Aldolase| HM:PFM:NREP 1 HM:PFM:REP 9->203|PF01081|7.9e-96|67.7|195/196|Aldolase| GO:PFM:NREP 2 GO:PFM GO:0003824|"GO:catalytic activity"|PF01081|IPR000887| GO:PFM GO:0008152|"GO:metabolic process"|PF01081|IPR000887| RP:SCP:NREP 1 RP:SCP:REP 1->212|1euaA|2e-57|97.2|212/213|c.1.10.1| HM:SCP:REP 1->213|1euaA_|3.9e-68|47.4|213/0|c.1.10.1|1/1|Aldolase| OP:NHOMO 724 OP:NHOMOORG 502 OP:PATTERN ------------------------1--1112------------------------------------- 1-1-2-----1--------------3------1-----341--2211-1---122--1-----1113141------------1-----111111-----1-2-211-1-1-----------------------------------1111111-1111------11111111------------12-1111-1-1-------1-------212211----13-2-----1---2------------------113-1-22-----1---13------1112122222---111111211111111111211111-22---222211-231111111-1-21--11111--1--1------------124-1------2221-11-131121--------22222222122-1111121222--222122222233212111232132122--------1--11---------------------------------11221----12222222222222222222222221111--2221-11111232111--111111111111-----------------------------------2-----------1-1-1111111-------1142111-3221211111111111111111-------------12111211112122111-11113121121222212233232111221212122112-111231111111--111111111111----1111111111-113111312-111--1111111111---4122221122111112222----------2244111113323522211111221111---1--------------11----1------1-------------------111-1-1- ------------------------------------------------------------------------------------------------------------2------------------------------------------------------2-----------1--11111--2--1--111----1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 213 STR:RPRED 100.0 SQ:SECSTR cTTccccHHHcccccTcEEEccccccTTHHHHHHHHHHTTccEEEEccccHHHHHHHHHccGGGGGGEEEcccTTHHHHTTcEEEccccccccHHHHHHTcTTcccTTcccEEEEEEccHHHHHTTGGGccEEEccccccccHHHHHHHHHTTcccTTEEEccccTTTHHHHHHTTccEEEEcHHHHTTccTTTccTTTccccHHHHHHHHHc DISOP:02AL 1-4| PSIPRED cccHHHHHHHHHHHcccEEEEEEccHHHHHHHHHHHHHccccEEEEEccccHHHHHHHHHHHHccccEEEEcccccHHHHHHHHHccccEEEcccccHHHHHHHHHccccEEcccccHHHHHHHHHccccEEEEccccccccHHHHHHHHcccccccEEEEccccHHHHHHHHccccEEEEEcHHHccHHHHHcccHHHHHHHHHHHHHHHHc //