[GTOP] [HELP] [ORGANISMS] [SEARCH] [SUMMARY]
Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : guaB
DDBJ      :guaB         inosine-5'-monophosphate dehydrogenase
Swiss-Prot:IMDH_SHIFL   RecName: Full=Inosine-5'-monophosphate dehydrogenase;         Short=IMP dehydrogenase;         Short=IMPDH;         Short=IMPD;         EC=1.1.1.205;

Homologs  Archaea  42/68 : Bacteria  826/915 : Eukaryota  192/199 : Viruses  0/175   --->[See Alignment]
c.1.5d.37.1
:488 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   3->484 1zfjA PDBj e-101 48.4 %
:RPS:PDB   3->90 1eepA PDBj 2e-15 64.8 %
:RPS:PDB   65->486 3bg3B PDBj 4e-44 12.2 %
:RPS:SCOP  7->91 1ak5A1  c.1.5.1 * 4e-27 43.6 %
:RPS:SCOP  82->204 2ef7A1  d.37.1.1 * 1e-19 26.1 %
:RPS:SCOP  185->467 1ak5A1  c.1.5.1 * 8e-52 24.3 %
:HMM:SCOP  1->478 1pvnA1 c.1.5.1 * 2.7e-137 57.9 %
:RPS:PFM   7->471 PF00478 * IMPDH e-134 58.7 %
:HMM:PFM   8->473 PF00478 * IMPDH 3.9e-151 63.7 347/351  
:BLT:SWISS 1->488 IMDH_SHIFL 0.0 97.5 %
:PROS 295->307|PS00487|IMP_DH_GMP_RED
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF68095.1 GT:GENE guaB GT:PRODUCT inosine-5'-monophosphate dehydrogenase GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION complement(2681129..2682595) GB:FROM 2681129 GB:TO 2682595 GB:DIRECTION - GB:GENE guaB GB:PRODUCT inosine-5'-monophosphate dehydrogenase GB:NOTE identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01302 GB:PROTEIN_ID ACF68095.1 GB:DB_XREF GI:194407876 GB:GENE:GENE guaB LENGTH 488 SQ:AASEQ MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPMLSAAMDTVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLPTTTLHEVKALTERNGFAGYPVVTEDNELVGIITGRDVRFVTDLNQPVSVYMTPKERLVTVREGEAREVVLAKMHEKRVEKALVVDDNFHLLGMITVKDFQKAERKPNSCKDEQGRLRVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGGNVATGAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVSDAVEALEGTGIPVIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLGAMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCATIDELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS GT:EXON 1|1-488:0| SW:ID IMDH_SHIFL SW:DE RecName: Full=Inosine-5'-monophosphate dehydrogenase; Short=IMP dehydrogenase; Short=IMPDH; Short=IMPD; EC=1.1.1.205; SW:GN Name=guaB; OrderedLocusNames=SF2554, S2726; SW:KW Acetylation; CBS domain; Complete proteome; GMP biosynthesis;Metal-binding; NAD; Oxidoreductase; Potassium; Purine biosynthesis;Repeat. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->488|IMDH_SHIFL|0.0|97.5|488/488| GO:SWS:NREP 5 GO:SWS GO:0006177|"GO:GMP biosynthetic process"|GMP biosynthesis| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| GO:SWS GO:0006164|"GO:purine nucleotide biosynthetic process"|Purine biosynthesis| PROS 295->307|PS00487|IMP_DH_GMP_RED|PDOC00391| SEG 220->229|vgaavgagag| SEG 234->248|vdalvaagvdvllid| SEG 279->294|atgagaralaeagcsa| SEG 347->363|iakaiaagasavmvgsm| BL:PDB:NREP 1 BL:PDB:REP 3->484|1zfjA|e-101|48.4|455/463| RP:PDB:NREP 2 RP:PDB:REP 3->90|1eepA|2e-15|64.8|88/314| RP:PDB:REP 65->486|3bg3B|4e-44|12.2|419/603| RP:PFM:NREP 1 RP:PFM:REP 7->471|PF00478|e-134|58.7|458/459|IMPDH| HM:PFM:NREP 1 HM:PFM:REP 8->473|PF00478|3.9e-151|63.7|347/351|IMPDH| GO:PFM:NREP 2 GO:PFM GO:0003824|"GO:catalytic activity"|PF00478|IPR001093| GO:PFM GO:0055114|"GO:oxidation reduction"|PF00478|IPR001093| RP:SCP:NREP 3 RP:SCP:REP 7->91|1ak5A1|4e-27|43.6|85/329|c.1.5.1| RP:SCP:REP 82->204|2ef7A1|1e-19|26.1|119/127|d.37.1.1| RP:SCP:REP 185->467|1ak5A1|8e-52|24.3|251/329|c.1.5.1| HM:SCP:REP 1->478|1pvnA1|2.7e-137|57.9|347/0|c.1.5.1|1/1|Inosine monophosphate dehydrogenase (IMPDH)| OP:NHOMO 1713 OP:NHOMOORG 1060 OP:PATTERN 21--------------11------211112221111111111111111-----111111111111-11 111-211222212122222-22222222222222222222112122211212112222112222222222211111111111-1111122111211---212111111111-------11-112-1111111111111111---11111-----1--------1--1---1-11----11-1-1111111211222222222222222221221222211122222222222112222222222222122222222222212322122222222222222222222211222222222222222222222222122111222211122111111111111111111111111111111111111111111111111111111111111111112122211111111111-11111111111111111111111111111111111111111111111111111121111111111---------------111111111111111111111111111111111111111111111111212222222222221111211111111111111211111111111111222111111222212111111111111111222222211111112221111111111111112111111211111-1111111-11122222222222222222-222222222222222222222222111222222222222222222222222112222222222221111111112222111111111111121111111111111111111111211111111111111111111112222222222222211111111111111111111111111111-1-1-1----2------------11------1-11111111-11 1111112-522-1111111-11111111111111111111111111111111111111111112111111112-13346511112211-11111111111111212-12148656844444444453E4Ol9-86C2423644441432343394424424A32222311323321111I1111121231211143332 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 486 STR:RPRED 99.6 SQ:SECSTR HHHcccccccTTcEEEccccccccGGGccccEEcccccEEcccEEEcccTTTccTHHHHHHHHTcHHHHHHHHHcHHHHHHHHHHccccEEEEcTHHHHHHcTTcHHHHHHTHHHHHcTTccEEGEEEETTHHHHHHHTccccHHHHHHHHHHHccccEEcGGGTTccccccHHHHHHHHHHHHTTTcEEEEccTTccHHHHHHHHHHHEEEccccTTcTTcccccHHHHHHHHHHHHHHTccEEEEETTccccHHHHHHHHHHHTTcTTccTTccHHHHHHHHHHTTccEEEEccGGGcTccccHHHHHccccHHHHHHHHHHHHHHHHTTGGGcGGGTccccHHHHHTTTTcccTTTccccHHHHHHHHHHHHHHTTcHHHHHHHHHHHHHHTTcccHHHHcTTTTccHHHHHHHTTTccTTcccHHHHHHHHTTcccccccHHHHcccccHHHHHHHHHHHcccHcccHHHHHHHHHcHHHHH## DISOP:02AL 1-2,4-4,483-489| PSIPRED ccHHHHHcccccEEEEccccccccHHHEEEEEEEccccEEcccEEcccccccccHHHHHHHHHcccEEEEcccccHHHHHHHHHHcccccccEEEccEEccccccHHHHHHHHHHccccEEEEEccccEEEEEEEcHHHccccccccEEEEEEEcccccEEEcccccHHHHHHHHHHccccEEEEEcccccEEEEEEEcccEEccccccccccccccccccEEEEcccHHHHHHHHHHHccccEEEEcccccccHHHHHHHHHHHHHcccccEEEEEcccHHHHHHHHHccccEEEEccccccccccHHHccccccHHHHHHHHHHHHHHcccEEEEEcccccHHHHHHHHHccccEEEEcHHHHccccccEEEEEEccEEEEEEcccHHHHHHHHHccccccccccccccccccccEEEEcccccHHHHHHHHHHHHHHHHHHcccccHHHHHHHcEEEEEcHHHHHcccccEEEEEEEcccccccc //