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Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : guaC
DDBJ      :guaC         guanosine monophosphate reductase
Swiss-Prot:GUAC_SALTY   RecName: Full=GMP reductase;         EC=1.7.1.7;AltName: Full=Guanosine 5'-monophosphate oxidoreductase;         Short=Guanosine monophosphate reductase;

Homologs  Archaea  40/68 : Bacteria  848/915 : Eukaryota  189/199 : Viruses  0/175   --->[See Alignment]
c.1.5
:347 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   3->338 2a7rA PDBj e-129 66.3 %
:RPS:PDB   9->336 2bznA PDBj 1e-43 66.8 %
:RPS:SCOP  5->336 1ak5A1  c.1.5.1 * 3e-73 26.1 %
:HMM:SCOP  6->337 1jr1A1 c.1.5.1 * 7.7e-103 40.7 %
:RPS:PFM   99->336 PF00478 * IMPDH 5e-48 41.1 %
:HMM:PFM   9->342 PF00478 * IMPDH 3.1e-114 45.0 327/351  
:BLT:SWISS 1->347 GUAC_SALTY 0.0 100.0 %
:PROS 176->188|PS00487|IMP_DH_GMP_RED
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF69085.1 GT:GENE guaC GT:PRODUCT guanosine monophosphate reductase GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION 159253..160296 GB:FROM 159253 GB:TO 160296 GB:DIRECTION + GB:GENE guaC GB:PRODUCT guanosine monophosphate reductase GB:NOTE identified by match to protein family HMM PF00478; match to protein family HMM TIGR01305 GB:PROTEIN_ID ACF69085.1 GB:DB_XREF GI:194408866 GB:GENE:GENE guaC LENGTH 347 SQ:AASEQ MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQTWSGVPIIAANMDTVGTFEMAQALAGFDILTAVHKHYTVEEWAAFINTASADVLKHVMVSTGTSDADFEKTVQILALNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVVTGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVSDGGCTMPGDVAKAFGGGADFVMLGGMLAGHEESGGSVVEENGEKFMLFYGMSSESAMNRHVGGVAKYRAAEGKTVKLPLRGPVGNTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRIFNSL GT:EXON 1|1-347:0| SW:ID GUAC_SALTY SW:DE RecName: Full=GMP reductase; EC=1.7.1.7;AltName: Full=Guanosine 5'-monophosphate oxidoreductase; Short=Guanosine monophosphate reductase; SW:GN Name=guaC; OrderedLocusNames=STM0141; SW:KW Complete proteome; Metal-binding; NADP; Oxidoreductase; Potassium. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->347|GUAC_SALTY|0.0|100.0|347/347| GO:SWS:NREP 3 GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| PROS 176->188|PS00487|IMP_DH_GMP_RED|PDOC00391| SEG 247->261|gheesggsvveenge| BL:PDB:NREP 1 BL:PDB:REP 3->338|2a7rA|e-129|66.3|335/338| RP:PDB:NREP 1 RP:PDB:REP 9->336|2bznA|1e-43|66.8|319/320| RP:PFM:NREP 1 RP:PFM:REP 99->336|PF00478|5e-48|41.1|236/459|IMPDH| HM:PFM:NREP 1 HM:PFM:REP 9->342|PF00478|3.1e-114|45.0|327/351|IMPDH| GO:PFM:NREP 2 GO:PFM GO:0003824|"GO:catalytic activity"|PF00478|IPR001093| GO:PFM GO:0055114|"GO:oxidation reduction"|PF00478|IPR001093| RP:SCP:NREP 1 RP:SCP:REP 5->336|1ak5A1|3e-73|26.1|307/329|c.1.5.1| HM:SCP:REP 6->337|1jr1A1|7.7e-103|40.7|327/0|c.1.5.1|1/1|Inosine monophosphate dehydrogenase (IMPDH)| OP:NHOMO 1706 OP:NHOMOORG 1077 OP:PATTERN ----------------11------211112221111111111111111-----111111111111-11 111-211222212122222-22222222222222222222112122211212112222112222222222211111111111-1111122111211---212111111111-------11-111-111111111111111111111111111-11--11-1111111--111111111111111111111211222222222222222221221222211122222222222112222222222222122222222222212222122222221122222222222211222222222222222222222222122111222211122111111111111111111111111111111111111111111111111111111111111111112122211111111111-11111111111111111111111111111111111111111111111111111121111111111---------------111111111111111111111111111111111111111111111111212222222222221111211111111111111211111111111111222111111222212111111111111111222222211111112221111111111111112111111211111-1111111-11122222222222222222-222222222222222222222222111222222222222222222222222112222222222221111111112222111111111111111111111111111111111111211111111111111111111112222232222233211111111111111111111111111111-1-1-1----2------------12------1-11111111-11 11-1112-522-1111111-111111111-1111111111111111111111111111111111111111112-12344311111111-11111111111111212-11148666863334444453E4Ji9-87C3443644442433443394324424-31222311323421111I1111121231211122522 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 345 STR:RPRED 99.4 SQ:SECSTR #cccccccccGGGEEEccccccccccTTccccEEEEcTTTccEEEEccEEEcccTTTccHHHHHHHHHTTcEEEccccccHHHHHHHHHHHcGGGcTTEEEEEcccHHHHHHHHHHHHHcTTccEEEEEcccTTcHHHHHHHHHHHHHcTTcEEEEEEEccHHHHHHHHHTTccEEEEcccccTTccHHHHHcccccHHHHHHHHHHHHHTTTcEEEEEcccccHHHHHHHHHTTccEEEEcTTTTTcTTccccEEEETTEEEEEEEcTTcHHHHHHcccccTTTccccccEEEEEccccHHHHHHHHHHHHHHHHHHHTcccGGGTTTTccEEEccccccccccc# DISOP:02AL 275-285,342-342,346-348| PSIPRED cccccccccccHHEEEccccEEccccccccHHHHHHHHHHcccccccEEEcccccEEEcHHHHHHHHHcccEEEEEccccHHHHHHHHHHHHHccccEEEEEEEEccccHHHHHHHHHccccccEEEEEccccccHHHHHHHHHHHHHccccEEEEEccccHHHHHHHHHccccEEEEccccccccHHHHHccccccHHHHHHHHHHHHHHcccEEEEEcccccHHHHHHHHHcccccHHHHHHHHccccccccEEEEccEEEEEEEccccHHHHccccccccEEEEccccEEEEEEcccHHHHHHHHHHHHHHHHHHcccccHHHHHHccEEEEEEEccccccccc //