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Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : mutS
DDBJ      :mutS         DNA mismatch repair protein MutS
Swiss-Prot:MUTS_SALTY   RecName: Full=DNA mismatch repair protein mutS;

Homologs  Archaea  19/68 : Bacteria  779/915 : Eukaryota  196/199 : Viruses  1/175   --->[See Alignment]
a.113.1c.37.1c.55.6d.75.2
:855 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   7->802 1ng9A PDBj 0.0 91.3 %
:BLT:PDB   822->855 2ok2A PDBj 1e-14 100.0 %
:RPS:PDB   10->802 1e3mA PDBj e-157 78.3 %
:RPS:SCOP  7->118 1e3mA4  d.75.2.1 * 2e-50 91.1 %
:RPS:SCOP  119->270 1e3mA3  c.55.6.1 * 1e-60 93.4 %
:RPS:SCOP  272->568 1e3mA1  a.113.1.1 * 5e-86 77.8 %
:RPS:SCOP  569->802 1e3mA2  c.37.1.12 * 2e-28 94.6 %
:HMM:SCOP  4->118 1e3mA4 d.75.2.1 * 1.8e-46 52.2 %
:HMM:SCOP  119->271 1e3mA3 c.55.6.1 * 8.3e-47 39.9 %
:HMM:SCOP  272->568 1e3mA1 a.113.1.1 * 7.6e-92 44.1 %
:HMM:SCOP  569->802 1e3mA2 c.37.1.12 * 1.5e-70 37.6 %
:RPS:PFM   13->123 PF01624 * MutS_I 3e-42 64.9 %
:RPS:PFM   135->254 PF05188 * MutS_II 1e-22 48.3 %
:RPS:PFM   266->564 PF05192 * MutS_III 3e-62 44.6 %
:RPS:PFM   572->795 PF00488 * MutS_V 4e-82 63.8 %
:HMM:PFM   569->800 PF00488 * MutS_V 3e-108 59.9 232/234  
:HMM:PFM   267->565 PF05192 * MutS_III 6.8e-67 47.8 207/219  
:HMM:PFM   13->124 PF01624 * MutS_I 2.2e-46 56.2 112/113  
:HMM:PFM   133->258 PF05188 * MutS_II 2.3e-36 41.3 126/137  
:BLT:SWISS 1->855 MUTS_SALTY 0.0 100.0 %
:PROS 690->706|PS00486|DNA_MISMATCH_REPAIR_2
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF68251.1 GT:GENE mutS GT:PRODUCT DNA mismatch repair protein MutS GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION 3024884..3027451 GB:FROM 3024884 GB:TO 3027451 GB:DIRECTION + GB:GENE mutS GB:PRODUCT DNA mismatch repair protein MutS GB:NOTE identified by match to protein family HMM PF00488; match to protein family HMM PF01624; match to protein family HMM PF05188; match to protein family HMM PF05190; match to protein family HMM PF05192; match to protein family HMM TIGR01070 GB:PROTEIN_ID ACF68251.1 GB:DB_XREF GI:194408032 GB:GENE:GENE mutS LENGTH 855 SQ:AASEQ MNESFDKDFSNHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPHHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDGKGYGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMALIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENASRGLCAAGCLLQYVKDTQRTSLPHIRSITMERQQDSIIMDAATRRNLEITQNLAGGVENTLAAVLDCTVTPMGSRMLKRWLHMPVRNTDILRERQQTIGALQDTVSELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELHAQLETVDSAPVQALRKKMGDFAELRDLLERAIIDAPPVLVRDGGVIAPGYHEELDEWRALADGATDYLDRLEIRERERTGLDTLKVGYNAVHGYYIQISRGQSHLAPINYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYDELFDLLLPHLADLQQSANALAELDVLVNLAERAWTLNYTCPTFTDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALLAYIGSYVPAQNVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATENSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLAAPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV GT:EXON 1|1-855:0| SW:ID MUTS_SALTY SW:DE RecName: Full=DNA mismatch repair protein mutS; SW:GN Name=mutS; OrderedLocusNames=STM2909; SW:KW ATP-binding; Complete proteome; Direct protein sequencing; DNA damage;DNA repair; DNA-binding; Nucleotide-binding. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->855|MUTS_SALTY|0.0|100.0|855/855| GO:SWS:NREP 5 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0006974|"GO:response to DNA damage stimulus"|DNA damage| GO:SWS GO:0006281|"GO:DNA repair"|DNA repair| GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| PROS 690->706|PS00486|DNA_MISMATCH_REPAIR_2|PDOC00388| SEG 350->369|lerilarlalrtarprdlar| SEG 528->546|qlydelfdlllphladlqq| BL:PDB:NREP 2 BL:PDB:REP 7->802|1ng9A|0.0|91.3|790/794| BL:PDB:REP 822->855|2ok2A|1e-14|100.0|34/402| RP:PDB:NREP 1 RP:PDB:REP 10->802|1e3mA|e-157|78.3|761/765| RP:PFM:NREP 4 RP:PFM:REP 13->123|PF01624|3e-42|64.9|111/113|MutS_I| RP:PFM:REP 135->254|PF05188|1e-22|48.3|120/135|MutS_II| RP:PFM:REP 266->564|PF05192|3e-62|44.6|298/309|MutS_III| RP:PFM:REP 572->795|PF00488|4e-82|63.8|224/229|MutS_V| HM:PFM:NREP 4 HM:PFM:REP 569->800|PF00488|3e-108|59.9|232/234|MutS_V| HM:PFM:REP 267->565|PF05192|6.8e-67|47.8|207/219|MutS_III| HM:PFM:REP 13->124|PF01624|2.2e-46|56.2|112/113|MutS_I| HM:PFM:REP 133->258|PF05188|2.3e-36|41.3|126/137|MutS_II| GO:PFM:NREP 12 GO:PFM GO:0005524|"GO:ATP binding"|PF01624|IPR007695| GO:PFM GO:0006298|"GO:mismatch repair"|PF01624|IPR007695| GO:PFM GO:0030983|"GO:mismatched DNA binding"|PF01624|IPR007695| GO:PFM GO:0005524|"GO:ATP binding"|PF05188|IPR007860| GO:PFM GO:0006298|"GO:mismatch repair"|PF05188|IPR007860| GO:PFM GO:0030983|"GO:mismatched DNA binding"|PF05188|IPR007860| GO:PFM GO:0005524|"GO:ATP binding"|PF05192|IPR007696| GO:PFM GO:0006298|"GO:mismatch repair"|PF05192|IPR007696| GO:PFM GO:0030983|"GO:mismatched DNA binding"|PF05192|IPR007696| GO:PFM GO:0005524|"GO:ATP binding"|PF00488|IPR000432| GO:PFM GO:0006298|"GO:mismatch repair"|PF00488|IPR000432| GO:PFM GO:0030983|"GO:mismatched DNA binding"|PF00488|IPR000432| RP:SCP:NREP 4 RP:SCP:REP 7->118|1e3mA4|2e-50|91.1|112/115|d.75.2.1| RP:SCP:REP 119->270|1e3mA3|1e-60|93.4|152/153|c.55.6.1| RP:SCP:REP 272->568|1e3mA1|5e-86|77.8|297/297|a.113.1.1| RP:SCP:REP 569->802|1e3mA2|2e-28|94.6|223/223|c.37.1.12| HM:SCP:REP 4->118|1e3mA4|1.8e-46|52.2|115/115|d.75.2.1|1/1|DNA repair protein MutS, domain I| HM:SCP:REP 119->271|1e3mA3|8.3e-47|39.9|153/0|c.55.6.1|1/1|DNA repair protein MutS, domain II| HM:SCP:REP 272->568|1e3mA1|7.6e-92|44.1|297/297|a.113.1.1|1/1|DNA repair protein MutS, domain III| HM:SCP:REP 569->802|1e3mA2|1.5e-70|37.6|234/234|c.37.1.12|1/1|P-loop containing nucleoside triphosphate hydrolases| OP:NHOMO 2590 OP:NHOMOORG 995 OP:PATTERN ------------------------22222222-----------1111111111----------1---- 423-------------------------------------2-----------------------------------------121221443413333112332328242311111111111111122222221222244221113321221122222221212222222212122222122122212222122233333233333333333222233322233232222223333333333333333323333322233223332222332221212222222222322122222222222222222222222332222222224454554555535454443445543222332233332323222342232222111111111111111111111111111111111-131111111111111111111111111111111111111111111111221111111211111111111111111111111111-11111111111111111111111111111111111111--111111-11121111111211111111111222111311112122222211222222222332334111----------1--1--1--1-11-331111111111111111111111111111111-1211211-11121111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--11111111111211111111111111-111111121111111111111111-1111111111111111111111111111111111111111111111--1122222222222212212-------------------------3333333223111 3322666-A4525556666466655466665655566676566765656655664666666645346426664446637766666644-6C566666566756665279585957575544555673B3wt8-7694455645634543563575764538F46572343545967569*88877A56E69F7675564 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- STR:NPRED 830 STR:RPRED 97.1 SQ:SECSTR ######ccGcGGGccHHHHHHHHHTcTTcEEEEEcTTEEEEEHHHHHHHHHHHTcccEEEccTTcccEEEEEEEGGGHHHHHHHHHHTTccEEEEEEcccGGGccccccEEEEEEEcTTTcccTTTccTTccccEEEEEEccccEEEEEEcTTTccEEEEccccHHHHHHHHHHHcccEEEEETTcccGcGTTTcTTEEEEcGGGGcHHHHHHHHHHHHTccccGGGTcTTcHHHHHHHHHHHHHHHHHHccccTTccccEEEccGGGccEcHHHHHHHTccccTTcccTTcHHHHHcccccHHHHHHHHHHHHcccccHHHHHHHHHHHHHHTTTHHHHHHHHHTTccHHHHHHHHHHTcccHHHHHHHHHHHTTHHHHHHHHHccccHHHHHHHHHHcccHHHHHHHHHHcccccccccTTcccccTTccHHHHHHHHHHTcHHHHHHHHHHHHHHHHTcTTcEEEEETTTEEEEEEEHHHHTTccETTcEEEEcccEEEEEcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGGHHHHHHHHHHHHHHHHHHHHHHHHHHTTccccEEcccccEEEEEEccTTTTTccccccccEEEEEccEcccEEEEccTccHHHHHHHHHHHHHHHHTTTccccccEEEEccccEEEEEEccHHHHHHHHHHHccTTcHHHHHHHHHccTTcEEEEcccccccTTHHHHHHHHHHHHHHHTTccEEEEEcccGGGGGGGHHHHTTEEEEEEEEEEccccEEEEEEEEcccccccHHHHHHHTTccHHHHHHHHHHHHHHHHTc###################HHccHHHHHHHHccGGGccHHHHHHHHHHHHTTc DISOP:02AL 1-11,98-110,795-822| PSIPRED ccccHHHHHHHccHHHHHHHHHHHHcccEEEEEEcccEEEEEHHHHHHHHHHHccEEcccccccccccccccccHHHHHHHHHHHHHcccEEEEEEEcccccccccccEEEEEEEEEccEEEcccccccccccEEEEEEEcccEEEEEEEEccccEEEEEEcccHHHHHHHHHHccccEEEEccccccHHHHHHccccEEccHHHccHHHHHHHHHHHHHHccccccccccccHHHHHHHHHHHHHHHHcccccccccccEEEccccEEEEcHHHHHHHcccccccccccccHHHHHHHcccHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHcccHHHHHHHHHHHHcccHHHHcccccEEcccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccEEEEEEccccEEEEEcHHHHHHcccccEEEEEccccEEEEcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccEEccccEEEEEEcccHHHHHHccccEEEEEEEEccccEEEEEEcccccHHHHHHHHHHHHHHHHHccccccccccEEccEEEEEEEEcccccHHccHHHHHHHHHHHHHHHHHcccccEEEEEcccccccHHHHHHHHHHHHHHHHHHcccEEEEEcccHHHHHHHHccccEEEEEEEEEEEccEEEEEEEEEEccccccHHHHHHHHHcccHHHHHHHHHHHHHHHccccccccccccHHHHHHHcccccHHHHHHHHHccccccccHHHHHHHHHHHHHHc //