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Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : panB
DDBJ      :panB         3-methyl-2-oxobutanoate hydroxymethyltransferase
Swiss-Prot:PANB_SALTY   RecName: Full=3-methyl-2-oxobutanoate hydroxymethyltransferase;         EC=2.1.2.11;AltName: Full=Ketopantoate hydroxymethyltransferase;         Short=KPHMT;

Homologs  Archaea  38/68 : Bacteria  696/915 : Eukaryota  121/199 : Viruses  0/175   --->[See Alignment]
c.1.12
:263 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   3->263 1m3uA PDBj e-127 92.3 %
:RPS:PDB   25->260 2csbA PDBj 3e-24 8.3 %
:RPS:SCOP  3->263 1m3uA  c.1.12.8 * 2e-41 85.4 %
:HMM:SCOP  3->261 1o66A_ c.1.12.8 * 3.9e-105 52.9 %
:RPS:PFM   2->259 PF02548 * Pantoate_transf 4e-77 54.3 %
:HMM:PFM   3->259 PF02548 * Pantoate_transf 5e-108 54.1 257/261  
:BLT:SWISS 1->263 PANB_SALTY e-138 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF67119.1 GT:GENE panB GT:PRODUCT 3-methyl-2-oxobutanoate hydroxymethyltransferase GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION complement(220169..220960) GB:FROM 220169 GB:TO 220960 GB:DIRECTION - GB:GENE panB GB:PRODUCT 3-methyl-2-oxobutanoate hydroxymethyltransferase GB:NOTE identified by match to protein family HMM PF02548; match to protein family HMM TIGR00222 GB:PROTEIN_ID ACF67119.1 GB:DB_XREF GI:194406900 GB:GENE:GENE panB LENGTH 263 SQ:AASEQ MKPTTISLLQKCKQEKKRFATITAYDYSFAKLFADEGINVMLVGDSLGMTIQGHDSTLPVTVEDIAYHTRAVRRGAPNCLLLSDLPFMAYATPEQACENAAIVMRAGANMVKIEGGAWLVDTVKMLTERAVPVCGHLGLTPQSVNIFGGYKIQGRGDAGQVLLDDALALEAAGAQLLVLECVPVELAKRVTEALSIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAEAGDMRAAVQQYMAEVESGVYPGEEHSFH GT:EXON 1|1-263:0| SW:ID PANB_SALTY SW:DE RecName: Full=3-methyl-2-oxobutanoate hydroxymethyltransferase; EC=2.1.2.11;AltName: Full=Ketopantoate hydroxymethyltransferase; Short=KPHMT; SW:GN Name=panB; OrderedLocusNames=STM0182; SW:KW Complete proteome; Cytoplasm; Magnesium; Metal-binding;Methyltransferase; Pantothenate biosynthesis; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->263|PANB_SALTY|e-138|100.0|263/263| GO:SWS:NREP 5 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0008168|"GO:methyltransferase activity"|Methyltransferase| GO:SWS GO:0015940|"GO:pantothenate biosynthetic process"|Pantothenate biosynthesis| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| SEG 160->180|qvllddalaleaagaqllvle| BL:PDB:NREP 1 BL:PDB:REP 3->263|1m3uA|e-127|92.3|261/262| RP:PDB:NREP 1 RP:PDB:REP 25->260|2csbA|3e-24|8.3|228/511| RP:PFM:NREP 1 RP:PFM:REP 2->259|PF02548|4e-77|54.3|258/261|Pantoate_transf| HM:PFM:NREP 1 HM:PFM:REP 3->259|PF02548|5e-108|54.1|257/261|Pantoate_transf| GO:PFM:NREP 2 GO:PFM GO:0003864|"GO:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"|PF02548|IPR003700| GO:PFM GO:0015940|"GO:pantothenate biosynthetic process"|PF02548|IPR003700| RP:SCP:NREP 1 RP:SCP:REP 3->263|1m3uA|2e-41|85.4|261/262|c.1.12.8| HM:SCP:REP 3->261|1o66A_|3.9e-105|52.9|259/0|c.1.12.8|1/1|Phosphoenolpyruvate/pyruvate domain| OP:NHOMO 929 OP:NHOMOORG 855 OP:PATTERN 1111111111111111-111111-1111-111----------------------1111111-----11 11-1111111111111111-111111111111111111111111111-111111111111111-1111111---------1--1111111111111---11121111111---------------111111111111111111111111111111111111111111111111111111111111111---111111111111111111111111111111111111111111-11111111111111111111---------------------------------------------------------------------11-111111111-1111111-----1----111111211--1111-11---11111111111113-11111111111111111111-11111211131-211122222222111111-1111111111111111111-111111---------------------------111112-111121222211111111111111121111111111112111111111111111111111111111111111111111111111-111111111111111111111111111-11111111111111111111111111112222111111111111111--11111--11111111111111111111-11111111111111111111111111111111111111111111111111111111111111111---111111111111211---------------1112111111212222221111211111111111111111211111111111111111111111111111-111111------------------------------------11-1111111111 ----111-----22111111111212111111111111111111111111111111111111111111-1111111111111111111-12112111111111111-111---------------------------------------------------------------1-1111I111111--31331121222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 263 STR:RPRED 100.0 SQ:SECSTR HHHHHHHHHHHHHHHcccEEEEcccEEEEcccHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHcHHHHTcHHHHHHHHHHHHHHHHHHHHHHHHHTccTTcccEEEEEETTEEHHHHHHTcTTcccHHHHHHTcTTTHHHHHHHTTccGGGcccccccTTccccHHHHHHHHHTTcTTTcccGGGTTTHHHHHHTTccccHHHHHHHHHcTTccHHHHHHHHTccHHHHHcccccccccHHHHHHHHHTTccccHHHHHHHHHH DISOP:02AL 1-1,257-264| PSIPRED cccccHHHHHHHHHccccEEEEEEccHHHHHHHHHccccEEEEEccHHHHHccccccHHHHHHHHHHHHHHHHccccccEEEEcccccccccHHHHHHHHHHHHHHcccEEEEcccHHHHHHHHHHHHccccEEEEccccHHHHHHcccEEEEcccHHHHHHHHHHHHHHHccccEEEEEcccHHHHHHHHHHccccEEEEcccccccHHHHHHHHHHccccccccHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccc //