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Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : panE.1
DDBJ      :panE         2-dehydropantoate 2-reductase
Swiss-Prot:PANE_SALTY   RecName: Full=2-dehydropantoate 2-reductase;         EC=1.1.1.169;AltName: Full=Ketopantoate reductase;         Short=KPA reductase;         Short=KPR;

Homologs  Archaea  26/68 : Bacteria  317/915 : Eukaryota  74/199 : Viruses  0/175   --->[See Alignment]
a.100.1c.2.1
:303 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   1->293 1yjqA PDBj e-156 87.7 %
:RPS:PDB   1->289 3egoB PDBj 2e-26 25.4 %
:RPS:SCOP  1->167 1ks9A2  c.2.1.6 * 5e-07 89.8 %
:RPS:SCOP  168->283 1ks9A1  a.100.1.7 * 2e-09 83.6 %
:HMM:SCOP  1->167 1ks9A2 c.2.1.6 * 1.1e-61 47.3 %
:HMM:SCOP  168->291 1ks9A1 a.100.1.7 * 5.5e-37 40.3 %
:RPS:PFM   3->140 PF02558 * ApbA 3e-11 34.1 %
:RPS:PFM   168->289 PF08546 * ApbA_C 1e-27 51.6 %
:HMM:PFM   168->289 PF08546 * ApbA_C 3.1e-41 48.4 122/125  
:HMM:PFM   3->143 PF02558 * ApbA 9.7e-30 31.4 140/151  
:BLT:SWISS 1->303 PANE_SALTY e-180 100.0 %

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF67418.1 GT:GENE panE.1 GT:PRODUCT 2-dehydropantoate 2-reductase GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION complement(533915..534826) GB:FROM 533915 GB:TO 534826 GB:DIRECTION - GB:GENE panE GB:PRODUCT 2-dehydropantoate 2-reductase GB:NOTE identified by match to protein family HMM PF02558; match to protein family HMM PF08546; match to protein family HMM TIGR00745 GB:PROTEIN_ID ACF67418.1 GB:DB_XREF GI:194407199 GB:GENE:GENE panE LENGTH 303 SQ:AASEQ MKITVLGCGALGQLWLSALCKHGHDVQGWLRVPQPYCSVNLIDTDGSFFNESLTANDPDFLAKSELLLVTLKAWQVSDAVRTLASTLPVTSPILLIHNGMGTIEELQNIQQPMLMGTITHAARRDGNIIIHVANGTTHIGPAREQDGDYSYLADILQGVLPDVAWHNNIRAEMWRKLAVNCVINPLTALWNCPNGELRHHTDEINAICEEVAAVIEREGYHTSADDLRYYVEQVIDSTAENISSMLQDVRAMRHTEIDYITGYLLKRARVHGLAVPENSRLFEMVKRKESEYERSGTGMPRPW GT:EXON 1|1-303:0| SW:ID PANE_SALTY SW:DE RecName: Full=2-dehydropantoate 2-reductase; EC=1.1.1.169;AltName: Full=Ketopantoate reductase; Short=KPA reductase; Short=KPR; SW:GN Name=panE; Synonyms=abpA; OrderedLocusNames=STM0434; SW:KW Complete proteome; Cytoplasm; Direct protein sequencing; NADP;Oxidoreductase; Pantothenate biosynthesis. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->303|PANE_SALTY|e-180|100.0|303/303| GO:SWS:NREP 4 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| GO:SWS GO:0015940|"GO:pantothenate biosynthetic process"|Pantothenate biosynthesis| BL:PDB:NREP 1 BL:PDB:REP 1->293|1yjqA|e-156|87.7|293/293| RP:PDB:NREP 1 RP:PDB:REP 1->289|3egoB|2e-26|25.4|284/291| RP:PFM:NREP 2 RP:PFM:REP 3->140|PF02558|3e-11|34.1|138/150|ApbA| RP:PFM:REP 168->289|PF08546|1e-27|51.6|122/125|ApbA_C| HM:PFM:NREP 2 HM:PFM:REP 168->289|PF08546|3.1e-41|48.4|122/125|ApbA_C| HM:PFM:REP 3->143|PF02558|9.7e-30|31.4|140/151|ApbA| GO:PFM:NREP 3 GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF08546|IPR013752| GO:PFM GO:0050661|"GO:NADP or NADPH binding"|PF08546|IPR013752| GO:PFM GO:0055114|"GO:oxidation reduction"|PF08546|IPR013752| RP:SCP:NREP 2 RP:SCP:REP 1->167|1ks9A2|5e-07|89.8|167/167|c.2.1.6| RP:SCP:REP 168->283|1ks9A1|2e-09|83.6|116/124|a.100.1.7| HM:SCP:REP 1->167|1ks9A2|1.1e-61|47.3|167/0|c.2.1.6|1/1|NAD(P)-binding Rossmann-fold domains| HM:SCP:REP 168->291|1ks9A1|5.5e-37|40.3|124/124|a.100.1.7|1/1|6-phosphogluconate dehydrogenase C-terminal domain-like| OP:NHOMO 456 OP:NHOMOORG 417 OP:PATTERN --1-11-----------111--111--1-1--11----1-1-11-12-------1111111------- -------------------------------------------------------------------1---------------1-111------------------------------------------------1--11-------------1-------------------------------------111111111111111111111111111111-11111111111111111111111111112-2---11-----------11-11-1111111111--------------1111111111111-11---1111---211111111111-1--1111---11-----3211-------------12-----------------11-11-------------------------1--------------------------11111111--1------------------------------------1--------1----1-----11-2-----1--1-1---12---1111111-1--------------------11-----1-1--------1-1-------------1---------------------------11111-1111111111111111111111111------------11111111111111111-11111111111111111111111111121222222222222221111111111111111111111---1----------1111-------------------------1-111112111111111-1----------11111111111111------------------------------------------------------------------------- ----11------1113111-211325111-111111111111111111-1--111111111-111----1--111------11111-1-11-1---112-----21--1-------------------------------------------------------------------11----------11--1--1--- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 295 STR:RPRED 97.4 SQ:SECSTR cEEEEEcccHHHHHHHHHHHTTTcEEEEEcccHHHHHHHHEEEEETTEEEEEccEEEccccccccEEEEcccGGGHHHHHHHHHTccccEEEEcccccHHHHHHHTcccccEEEEEEEccEEEEcccEEEEEEcccEEEEEcTTccTHHHHHHHccccTTccEEEcccHHHHHHHHHHHHHHHHHHHHHHTccTTHHHHcHHHHHHHHHHHHHHHTcccHHHHHHHHHHHHHHHHHHTTTcccHHHHHHTTTccccHHHHHHHHHHHHHHTTcccHHHHHHHHHHHHHcTcTccc######## DISOP:02AL 293-296,299-304| PSIPRED cEEEEEcccHHHHHHHHHHHHcccEEEEEEccHHHHHHHHcccccccccccccccccHHHHccccEEEEEccccHHHHHHHHHHHHcccccEEEEEcccHHHHHHHHHccccEEEEEEEEEEEccccEEEEcccccEEEEEcccccHHHHHHHHHHHcccccEEEcccHHHHHHHHHHHHHHHHHHHHHHcccHHHHHccHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHccccccccHHHHHHHcccccHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHcccccccccc //