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Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : pepN
DDBJ      :pepN         aminopeptidase N
Swiss-Prot:AMPN_ECOLI   RecName: Full=Aminopeptidase N;         EC=3.4.11.2;AltName: Full=Alpha-aminoacylpeptide hydrolase;

Homologs  Archaea  28/68 : Bacteria  572/915 : Eukaryota  195/199 : Viruses  0/175   --->[See Alignment]
b.98.1d.92.1
:870 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   4->870 2dqmA PDBj 0.0 94.0 %
:RPS:PDB   4->870 2dqmA PDBj e-176 91.5 %
:RPS:SCOP  5->192 1gw6A2  b.98.1.1 * 5e-35 20.7 %
:RPS:SCOP  205->451 1gw6A3  d.92.1.13 * 3e-57 22.7 %
:HMM:SCOP  1->193 1hs6A2 b.98.1.1 * 1.6e-47 34.4 %
:HMM:SCOP  202->450 1hs6A3 d.92.1.13 * 9.3e-77 38.9 %
:RPS:PFM   22->384 PF01433 * Peptidase_M1 1e-57 42.4 %
:RPS:PFM   461->870 PF11940 * DUF3458 e-113 52.0 %
:HMM:PFM   458->870 PF11940 * DUF3458 2.3e-162 51.2 408/410  
:HMM:PFM   90->384 PF01433 * Peptidase_M1 7e-65 26.8 287/391  
:HMM:PFM   416->478 PF11838 * DUF3358 0.00096 23.8 63/428  
:BLT:SWISS 1->870 AMPN_ECOLI 0.0 94.0 %
:PROS 294->303|PS00142|ZINC_PROTEASE
:COIL
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF66052.1 GT:GENE pepN GT:PRODUCT aminopeptidase N GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION 1148866..1151478 GB:FROM 1148866 GB:TO 1151478 GB:DIRECTION + GB:GENE pepN GB:PRODUCT aminopeptidase N GB:NOTE identified by match to protein family HMM PF01433; match to protein family HMM TIGR02414 GB:PROTEIN_ID ACF66052.1 GB:DB_XREF GI:194405833 GB:GENE:GENE pepN LENGTH 870 SQ:AASEQ MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAEKTVVTAISQAVRHGAPDAPLRLDGEDLTLVSIHVNDAPWTAYKEEEGALVISDLPERFTLRIVNEISPAANTALEGLYQSGDALCTQCEAEGFRHITWYLDRPDVLARFTTKIIADKSKYPFLLSNGNRVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKWDEARFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRISNVRTMRGLQFAEDASPMAHPIRPDKVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPIVTVKDDYNPETEQYTLTISQRTPATADQAEKQPLHIPFAIELYDNEGNVIPLQKGGHPVNAVLNVTQAEQTFTFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSANEIAELFEVIDPIAIAQVREALTRTLAAELADEFLAIYNANHLDEYRVDHGDIGKRTLRNACLRFLAFGETELANTLVSKQYRDANNMTDALAALSAAVAAQLPCRDTLMQEYDDKWHQDGLVMDKWFILQSTSPAENVLETVRGLLKHRSFSMSNPNRIRSLIGAFAGSNPAAFHAQDGSGYQFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDDKRQEKMRAALEQLKGLENLSGDLYEKITKALA GT:EXON 1|1-870:0| SW:ID AMPN_ECOLI SW:DE RecName: Full=Aminopeptidase N; EC=3.4.11.2;AltName: Full=Alpha-aminoacylpeptide hydrolase; SW:GN Name=pepN; OrderedLocusNames=b0932, JW0915; SW:KW 3D-structure; Aminopeptidase; Cell inner membrane; Cell membrane;Complete proteome; Direct protein sequencing; Hydrolase; Membrane;Metal-binding; Metalloprotease; Protease; Zinc. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->870|AMPN_ECOLI|0.0|94.0|870/870| GO:SWS:NREP 8 GO:SWS GO:0004177|"GO:aminopeptidase activity"|Aminopeptidase| GO:SWS GO:0005886|"GO:plasma membrane"|Cell inner membrane| GO:SWS GO:0005886|"GO:plasma membrane"|Cell membrane| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| GO:SWS GO:0016020|"GO:membrane"|Membrane| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0008237|"GO:metallopeptidase activity"|Metalloprotease| GO:SWS GO:0008233|"GO:peptidase activity"|Protease| PROS 294->303|PS00142|ZINC_PROTEASE|PDOC00129| COIL:NAA 27 COIL:NSEG 1 COIL:REGION 842->868| SEG 641->653|realtrtlaaela| SEG 713->725|alaalsaavaaql| BL:PDB:NREP 1 BL:PDB:REP 4->870|2dqmA|0.0|94.0|867/867| RP:PDB:NREP 1 RP:PDB:REP 4->870|2dqmA|e-176|91.5|867/867| RP:PFM:NREP 2 RP:PFM:REP 22->384|PF01433|1e-57|42.4|356/379|Peptidase_M1| RP:PFM:REP 461->870|PF11940|e-113|52.0|410/415|DUF3458| HM:PFM:NREP 3 HM:PFM:REP 458->870|PF11940|2.3e-162|51.2|408/410|DUF3458| HM:PFM:REP 90->384|PF01433|7e-65|26.8|287/391|Peptidase_M1| HM:PFM:REP 416->478|PF11838|0.00096|23.8|63/428|DUF3358| GO:PFM:NREP 2 GO:PFM GO:0008237|"GO:metallopeptidase activity"|PF01433|IPR014782| GO:PFM GO:0008270|"GO:zinc ion binding"|PF01433|IPR014782| RP:SCP:NREP 2 RP:SCP:REP 5->192|1gw6A2|5e-35|20.7|188/208|b.98.1.1| RP:SCP:REP 205->451|1gw6A3|3e-57|22.7|238/252|d.92.1.13| HM:SCP:REP 1->193|1hs6A2|1.6e-47|34.4|189/208|b.98.1.1|1/1|Leukotriene A4 hydrolase N-terminal domain| HM:SCP:REP 202->450|1hs6A3|9.3e-77|38.9|239/252|d.92.1.13|1/1|Metalloproteases ("zincins"), catalytic domain| OP:NHOMO 1891 OP:NHOMOORG 795 OP:PATTERN ------21222222221211111----------------------11--1111--------222--11 1111421111111111111-11111111111122221123-2221113211123222211123221173311111111----------11-1-1--1--113-1131211------------------1-1----1----------111-111--111111111112111111-1111111-1-----------------------------------------------------------------------111111111111111111111111111111111111111111111111111111111111--111---1--1----------------------------------------111-------31111111111-----------11111111111-11111111111-1111111111111112-1111111111--------11111-1-------------------------------122121111122222222222222122222222111111122211111111121111111-1111111111111111-1-1----------111--1-1-221154-1--------------------1----11111212123213222223233221223222--11111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--131111122221111111111111111111122222211111111111111111111111111111-111-1111111111111113434433311111-1-221111------------------------------------------------- 1111562-433-55333223232333322222222213132332333334334333343333452242324343433-3331122121-431314122224214543323GDDBEBF5655473785A3L*C1B8J656581A9A77555C23F396687GOEH9M9RDQb9BCG2313H3212244793382357672 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 867 STR:RPRED 99.7 SQ:SECSTR ###ccccEEGGGcccccEEEEEEEEEEEcccccEEEEEEEEEEEcccTTccEEEEccccEEEEEEETTEEcccEEEETTEEEEcccccEEEEEEEEEEcGGGcTTccEEEEETTEEEEEcTTTTGGGTccccccTTcccEEEEEEEEETTTccEEEEccEEEEEEEccTTEEEEEEEccccccGGGccEEEEccEEEEEEEEcTTccEEEEEEEEcTTcGGGcHHHHHHHHHHHHHHHHHHcccccccEEEEEEEccccccEEccTTEEEEEGGGTcccTTTccHHHHHHHHHHHHHHHHTTTcTTTEEEccGGGHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHTHHHHHTcTTcccccccEEccGGGGccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTEEEcHHHHHHHHHHHHTcccTTTTHHHHcccccEEEEEEEEETTTTEEEEEEEEEccccTTccccccccEEEEEEEEcTTccccccEETTEEcccEEEEcccEEEEEEcccccccEEEEcGGGccccEEEccccHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHTTTccccccHHHHHHHHHHHHcTTccHHHHHHHTccccHHHHHTTcccccHHHHHHHHHHHHHHHHHHTHHHHHHHHHHTccccccccHHHHHHHHHHHHHHHHHTTccHHHHHHHHHHHHHHcccHHHHHHHHHHHHHTTcTTHHHHHHHHHHHHTTcHHHHHHHHHHHHTcccTTHHHHHHHGGGcTTccTTcHHHHHHHHHHHHHHcHHHHTcTTcHHHHHHHHHHHHHHHHcHHHHHHHHHHHHTGGGccHHHHHHHHHHHHHHHTcTTccHHHHHHHHHHHc DISOP:02AL 1-4| PSIPRED cccccccccHHHccccccEEEEEEEEEEEcccEEEEEEEEEEEEccccccEEEEEccccEEEEEEEccEEEccEEccccEEEEEcccccEEEEEEEEEccccccccccEEEEccEEEEEcccccccEEEEEccccccccEEEEEEEEEcccEEEEEccccccccEEccccEEEEEEEccccccHHHEEEEEEccEEEEEEEEccccccEEEEEEEcHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccEEEEcccccccccccccccccccEEEcccccccHHHHHHHHHHHHHHHHHHHcccEEccccHHHHHHccHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHcccccccccccccccccHHHHccHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHcccccccHHHHHHHHHHHccccHHHHHHHHccccccEEEEEEccccccEEEEEEEEEEEccccccccccEEEEEEEEEEEcccccEEEEEEcccccEEEEEEcccEEEEEEccccHHHHHHHHcccccEEEEEccccHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHccccccccccHHHHHHHHHHHccccccHHHHHHHHccccHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHccccHHHHHHHHHHHHccccHHHHHHHHHHHHHcccHHHHHHHHHHHcccccccHHHHHHHHHHccccccccccHHHHHHHHHHccccHHcccccccHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHccccccccHHHHHHHHHc //