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Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : pntA
DDBJ      :pntA         NAD(P) transhydrogenase, alpha subunit
Swiss-Prot:PNTA_ECOLI   RecName: Full=NAD(P) transhydrogenase subunit alpha;         EC=1.6.1.2;AltName: Full=Nicotinamide nucleotide transhydrogenase subunit alpha;AltName: Full=Pyridine nucleotide transhydrogenase subunit alpha;

Homologs  Archaea  7/68 : Bacteria  635/915 : Eukaryota  135/199 : Viruses  0/175   --->[See Alignment]
c.2.1c.23.12
:509 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   2->375 1x15A PDBj e-180 92.9 %
:RPS:PDB   1->164 2eezA PDBj 9e-28 34.0 %
:RPS:PDB   238->336 2c2xA PDBj 6e-14 19.5 %
:RPS:SCOP  2->163 1f8gA2  c.23.12.2 * 1e-57 40.7 %
:RPS:SCOP  137->317 1pjbA1  c.2.1.4 * 6e-29 26.7 %
:RPS:SCOP  322->370 1f8gA2  c.23.12.2 * 7e-07 30.6 %
:HMM:SCOP  1->168 1pjcA2 c.23.12.2 * 1.8e-59 49.7 %
:HMM:SCOP  137->318 1pjcA1 c.2.1.4 * 1.3e-42 41.4 %
:RPS:PFM   4->137 PF05222 * AlaDh_PNT_N 3e-41 62.7 %
:RPS:PFM   148->295 PF01262 * AlaDh_PNT_C 7e-38 55.9 %
:HMM:PFM   147->311 PF01262 * AlaDh_PNT_C 3.5e-58 50.0 164/168  
:HMM:PFM   4->137 PF05222 * AlaDh_PNT_N 3.5e-54 56.0 134/136  
:BLT:SWISS 1->509 PNTA_ECOLI 0.0 92.1 %
:PROS 4->30|PS00836|ALADH_PNT_1
:PROS 170->195|PS00837|ALADH_PNT_2
:TM
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF70095.1 GT:GENE pntA GT:PRODUCT NAD(P) transhydrogenase, alpha subunit GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION 1602837..1604366 GB:FROM 1602837 GB:TO 1604366 GB:DIRECTION + GB:GENE pntA GB:PRODUCT NAD(P) transhydrogenase, alpha subunit GB:NOTE identified by match to protein family HMM PF01262; match to protein family HMM PF05222; match to protein family HMM TIGR00561 GB:PROTEIN_ID ACF70095.1 GB:DB_XREF GI:194409876 GB:GENE:GENE pntA LENGTH 509 SQ:AASEQ MRIGIPKERLPNETRVAATPKTVEQLLKLGFSVAIESGAGQLASFDDKAFAQAGADIVDGNAIWQSEIILKVNAPEEDEIALLNPGTTLVSFIWPAQNPGLMEKLAERKVTVMAMDSVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAAGKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKEEAGSGDGYAKVMSEAFIKAEMALFAAQAKEVDIIVTTALIPGKPAPKLITRDMVDSMKAGSVIVDLAAQNGGNCEYTVANQVVTTDNGVKVIGYTDLPGRLPTQSSQLYGTNLVNLLKLLCKEKDGNIDVDFDDVVIRGVTVIRDGDITWPAPPIQVSAQPQAAPKAAPAPKEPEKPASPWRKYALMALAIILFGWLADVAPKEFLGHFTVFALACVVGYYVVWNVSHALHTPLMSVTNAISGIIVVGALLQIGQGGWVSFLSFIAVLIASINIFGGFTVTQRMLKMFRKN GT:EXON 1|1-509:0| SW:ID PNTA_ECOLI SW:DE RecName: Full=NAD(P) transhydrogenase subunit alpha; EC=1.6.1.2;AltName: Full=Nicotinamide nucleotide transhydrogenase subunit alpha;AltName: Full=Pyridine nucleotide transhydrogenase subunit alpha; SW:GN Name=pntA; OrderedLocusNames=b1603, JW1595; SW:KW 3D-structure; Cell inner membrane; Cell membrane; Complete proteome;Direct protein sequencing; Membrane; NAD; NADP; Oxidoreductase;Transmembrane. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->509|PNTA_ECOLI|0.0|92.1|509/510| GO:SWS:NREP 6 GO:SWS GO:0005886|"GO:plasma membrane"|Cell inner membrane| GO:SWS GO:0005886|"GO:plasma membrane"|Cell membrane| GO:SWS GO:0016020|"GO:membrane"|Membrane| GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| GO:SWS GO:0016021|"GO:integral to membrane"|Transmembrane| PROS 4->30|PS00836|ALADH_PNT_1|PDOC00654| PROS 170->195|PS00837|ALADH_PNT_2|PDOC00654| TM:NTM 5 TM:REGION 169->191| TM:REGION 404->425| TM:REGION 427->449| TM:REGION 451->473| TM:REGION 476->498| SEG 170->189|vigagvaglaaigaanslga| SEG 376->398|saqpqaapkaapapkepekpasp| BL:PDB:NREP 1 BL:PDB:REP 2->375|1x15A|e-180|92.9|368/370| RP:PDB:NREP 2 RP:PDB:REP 1->164|2eezA|9e-28|34.0|162/343| RP:PDB:REP 238->336|2c2xA|6e-14|19.5|87/280| RP:PFM:NREP 2 RP:PFM:REP 4->137|PF05222|3e-41|62.7|134/136|AlaDh_PNT_N| RP:PFM:REP 148->295|PF01262|7e-38|55.9|145/164|AlaDh_PNT_C| HM:PFM:NREP 2 HM:PFM:REP 147->311|PF01262|3.5e-58|50.0|164/168|AlaDh_PNT_C| HM:PFM:REP 4->137|PF05222|3.5e-54|56.0|134/136|AlaDh_PNT_N| GO:PFM:NREP 4 GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF05222|IPR007886| GO:PFM GO:0055114|"GO:oxidation reduction"|PF05222|IPR007886| GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF01262|IPR007698| GO:PFM GO:0055114|"GO:oxidation reduction"|PF01262|IPR007698| RP:SCP:NREP 3 RP:SCP:REP 2->163|1f8gA2|1e-57|40.7|162/201|c.23.12.2| RP:SCP:REP 137->317|1pjbA1|6e-29|26.7|161/168|c.2.1.4| RP:SCP:REP 322->370|1f8gA2|7e-07|30.6|49/201|c.23.12.2| HM:SCP:REP 1->168|1pjcA2|1.8e-59|49.7|163/194|c.23.12.2|1/1|Formate/glycerate dehydrogenase catalytic domain-like| HM:SCP:REP 137->318|1pjcA1|1.3e-42|41.4|162/168|c.2.1.4|1/1|NAD(P)-binding Rossmann-fold domains| OP:NHOMO 1341 OP:NHOMOORG 777 OP:PATTERN -----------------------------2--------111112------------------------ -24131-------133333-323335313333222232433-1-11112112334111---12341222111222111---14-----1111-2-2---11211222231--------------122122112121---11----223433321122212222323123231121111211111113311-11122222222222222212221122322212111111111212222222222222211111--1-11------------11--1----------1---1-1--------------------1--------------------------11-------1-1----11-11--11-111----1-23333-----323222222222222222222212-22222222322-311322732233224332212221222222222223112-233------------22221222-2222----33333-122132333324222233632222225233H742322422-222231421121-1-3211111113331131132-1-1411111-11111111-33231111-----------1-1111111-------222314213121111112221112123111---2113------111111-1111111111-1111111111111111111111111111111111111111111111111111-111111111111---133333333322222111111111112111222222222233222122223-2222-22----------22232222222222111-1--111------2-222222----------1----------------11-----------------32- 1122111-1------11-1-111112111111111111111111111111111111111111---------------------------1111111---1-------12-2252213111111162111262-1211111111211111111131112213412121-11-112--1218---2---111--32----2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 375 STR:RPRED 73.7 SQ:SECSTR cEEEEcccccTTcccccccHHHHHHHHHTTcEEEEETTTTGGGTccHHHHHHHTcEEEcHHHHTTccEEEccccccGGGGGGccTTcEEEEcccGGGcHHHHHHHHHHTcEEEEGGGcccccTTcccTTTHHHHHHHHHHHHHHHHHHTcGGGTcccccTTccTccEEEEEcccHHHHHHHHHHHHTTcHHHHTTccGGGEEEEEEETTEEEEccTTccHHHHcTTcHHHHTTccTTTcccHHHHHTTccEEEEccccTTcccTTcccGGGHTTccTTcEEEEccEEEETTEEEEcccGGGHHTcGGTccEEEccccccHHHHHHHHHHHHHHHHHHHcTTccccccccTTcHHHHHHEEEETTEEccccccccc###################################################################################################################################### DISOP:02AL 381-392,508-510| PSIPRED cEEEEEccccccccEEEccHHHHHHHHHcccEEEEEccccccccccHHHHHHcccEEEcHHHHHHccEEEEEccccHHHHHHcccccEEEEEccccccHHHHHHHHHcccEEEEEHHcccccccccEEEEEccHHHHHHHHHHHHHHHHHHHcccccccccccccccEEEEccHHHHHHHHHHHHHcccEEEEEEccHHHHHHHHHccccEEEEcccccccccccccccccHHHHHHHHHHHHHHHccccEEEEEEEEccccccccccHHHHHHcccccEEEEEEEccccccccccccccEEEEccEEEEEcccHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccccHHHHHccEEEEccEEcccccccccccccccccccccccccccccccHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHccccHHHcccHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcc //