[GTOP] [HELP] [ORGANISMS] [SEARCH] [SUMMARY]
Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : prpE
DDBJ      :prpE         propionate--CoA ligase
Swiss-Prot:PRPE_SALTY   RecName: Full=Propionate--CoA ligase;         EC=6.2.1.17;AltName: Full=Propionyl-CoA synthetase;

Homologs  Archaea  53/68 : Bacteria  697/915 : Eukaryota  196/199 : Viruses  0/175   --->[See Alignment]
e.23.1
:628 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   7->622 2p2bB PDBj e-123 40.0 %
:RPS:PDB   37->601 2d1sA PDBj 1e-65 16.7 %
:RPS:SCOP  2->627 1pg3A  e.23.1.1 * 9e-80 35.0 %
:HMM:SCOP  3->628 1pg4A_ e.23.1.1 * 1.1e-167 30.4 %
:RPS:PFM   3->63 PF11930 * DUF3448 1e-17 54.1 %
:RPS:PFM   85->524 PF00501 * AMP-binding 9e-44 35.4 %
:HMM:PFM   85->525 PF00501 * AMP-binding 3.8e-93 27.8 417/418  
:HMM:PFM   3->75 PF11930 * DUF3448 1.8e-28 46.6 73/82  
:BLT:SWISS 1->628 PRPE_SALTY 0.0 99.7 %
:PROS 237->248|PS00455|AMP_BINDING
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF67241.1 GT:GENE prpE GT:PRODUCT propionate--CoA ligase GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION 468814..470700 GB:FROM 468814 GB:TO 470700 GB:DIRECTION + GB:GENE prpE GB:PRODUCT propionate--CoA ligase GB:NOTE identified by match to protein family HMM PF00501; match to protein family HMM TIGR02316 GB:PROTEIN_ID ACF67241.1 GB:DB_XREF GI:194407022 GB:GENE:GENE prpE LENGTH 628 SQ:AASEQ MSFSEFYQRSINEPEAFWAEQARRIDWRQPFTQTLDHSRPPFARWFCDGTTNLCHNAVDRWLDKQPEALALIAVSSETDEERTFTFSQLHDEVNIVAAMLLSLGVQRGDRVLVYMPMIAEAQITLLACARIGAIHSVVFGGFASHSVAARIDDARPALIVSADAGARGGKILPYKKLLDDAIAQAQHQPKHVLLVDRGLAKMAWVDGRDLDFATLRQQHLGASVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGGVFFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTYPDCGVWWKIVEKYQVNRMFSAPTAIRVLKKFPTAQIRNHDLSSLEALYLAGEPLDEPTASWVTETLGVPVIDNYWQTESGWPIMALARALDDRPSRLGSPGVPMYGYNVQLLNEVTGEPCGINEKGMLVIEGPLPPGCIQTIWGDDARFVKTYWSLFNRQVYATFDWGIRDAEGYYFILGRTDDVINIAGHRLGTREIEESISSYPNVAEVAVVGIKDALKGQVAVAFVIPKQSDTLADREAARDEENAIMALVDNQIGHFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLQQIRQAIEE GT:EXON 1|1-628:0| SW:ID PRPE_SALTY SW:DE RecName: Full=Propionate--CoA ligase; EC=6.2.1.17;AltName: Full=Propionyl-CoA synthetase; SW:GN Name=prpE; OrderedLocusNames=STM0371; SW:KW ATP-binding; Complete proteome; Ligase; Nucleotide-binding. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->628|PRPE_SALTY|0.0|99.7|628/628| GO:SWS:NREP 3 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| PROS 237->248|PS00455|AMP_BINDING|PDOC00427| SEG 550->559|adreaardee| BL:PDB:NREP 1 BL:PDB:REP 7->622|2p2bB|e-123|40.0|602/639| RP:PDB:NREP 1 RP:PDB:REP 37->601|2d1sA|1e-65|16.7|528/538| RP:PFM:NREP 2 RP:PFM:REP 3->63|PF11930|1e-17|54.1|61/85|DUF3448| RP:PFM:REP 85->524|PF00501|9e-44|35.4|396/405|AMP-binding| HM:PFM:NREP 2 HM:PFM:REP 85->525|PF00501|3.8e-93|27.8|417/418|AMP-binding| HM:PFM:REP 3->75|PF11930|1.8e-28|46.6|73/82|DUF3448| GO:PFM:NREP 2 GO:PFM GO:0003824|"GO:catalytic activity"|PF00501|IPR000873| GO:PFM GO:0008152|"GO:metabolic process"|PF00501|IPR000873| RP:SCP:NREP 1 RP:SCP:REP 2->627|1pg3A|9e-80|35.0|611/634|e.23.1.1| HM:SCP:REP 3->628|1pg4A_|1.1e-167|30.4|615/643|e.23.1.1|1/1|Acetyl-CoA synthetase-like| OP:NHOMO 6675 OP:NHOMOORG 946 OP:PATTERN 54-2--8BECEEEDDC2174643E744322563261--333317546854232----1---444---2 2377H221223627JSEDD-CO33LSDDDDDCORVROcxk4I6O3114254-959668--9791BEPJDG5--------273F213212222-2--1--21211242321---------------33233313343A99DE222C65353245--11111211111473B111111111111145576--1D8CCCCCCBBE9DBDBDA67AAADCDD9HDCC45222222D3122222222222222222231-1-11-2-----1112-1-123111-------------------------------------------11---21111111-1-7-22------41-81-51C82261--941111---721555A1111144RMO536QHQLJ46664465657-87887F687DF-844A67897B88CE554BAD5666B9D33333333A3211894-----------------------------2A9Q6-5GG8EDGHJGF88887CCGKEFEE7FQAQUXdV35HG98BBBAP9GHPJ3371121541222222232F874YH95566456555-2631423454564D598112--11111-111-11-111222411551543544635555538554547465488--12743------63544226779699776-6767776677776775775435249C37566777767666667646355651-233333322233---311121544223736111-11-1-1-11126667647799A4BBECCFDF79DC9767B1----1-1-12227444446646644443443331111--2-221122--------1-------------------------------------21- 1111VU4-621-677GF9BBCB8EAEG999A67BB9BD8EAECACB94799BEE87A679A962232232342223333332222223-9I6F7484443537FCE1667NDJ9D9D94575B7NH6J6T*F1HDL9768C86A767654C43L8E98EA8H7VAHAF9GF4BDF1335H34374JDGdAMH43H9D96 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 626 STR:RPRED 99.7 SQ:SECSTR GGTTGGcccEEEcTTccTTTcHHHHTTccTTcTTcETcEEccccccccccccHHHHHHHHHHHHHHHHTcEEEEEEETTTccEEEHHHHHHHHHHHHHHHHHTTccTTcEEEEEccccTTTHHHHHHHHHHTcEEEEEcTTccHHHHHHHHHHHcccEEEEcTTTHHHHHHHHHHHHcTTcEEEEcccccEEEETTcccccTTcccHHHHHHTccTTccGGGcccccccTTTcEEEEEcccccccccccEEEEHHHHHHHHHHHTcTcccccTTcEEEEcccTTcHHHHHHHHHHHHTTcEEEEEEccccccccHHHHHHHHHHTTEEEEEEcHHHHHHHHHccTccGGGcccTTccEEEEccccccHHHHHHHHHHTTccccEEEEEcGGGccEEEEccTTcccTccTTcccEEcTTcEEEEEcTTTcccccTTccEEEEEEccTcTTcccEETTcHHHHHHHccTEETTccEEEEEEEEEcTTccEEEEEEGGGccccTTccccHHHHHHHHHTcTTEEEEEEEEEEETTTEEEEEEEEEEcTTcTccHTcccccHHHHHHHHHTTccGGGccTTcEEEcccccccTTccccHHHHHHHHcHHccEEEEEEEEEETTEEEEEEE## DISOP:02AL 628-629| PSIPRED ccHHHHHHHHHHcHHHHHHHHHHHHEEcccHHHHccccccccccccccccEEHHHHHHHHHHHHccccEEEEEEccccccEEEEEHHHHHHHHHHHHHHHHHcccccccEEEEEccccHHHHHHHHHHHHHccEEEEccccccHHHHHHHHHHcccEEEEEEcccccccccccHHHHHHHHHHHccccccEEEEEEcccccccccccccccHHHHHHHcccccccccccccccEEEEEEcccccccccEEEEcHHHHHHHHHHHHHHHcccccccEEEEEccHHHHHHHHHHHHHHHHHccEEEEEccccccccHHHHHHHHHHHcccEEEcHHHHHHHHHHccccHHHccccccEEEEEEccccccHHHHHHHHHHHccEEEEEcccccHHHHHEEccccccccccccccccccccccEEEEEccccccccccccEEEEEEEcccccHHHccccccHHHHHHHHHHHccccEEEEccEEEEccccEEEEEcccccEEEEccEEEcHHHHHHHHHHcccEEEEEEEEccccccccEEEEEEEEcccccccHHHHHHHHHHHHHHHHHHHccccccccEEEEEccccccccccEEHHHHHHHHcccccccccccccHHHHHHHHHHHcc //