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Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 (sent8)
Gene : trpD
DDBJ      :trpD         anthranilate synthase, component II
Swiss-Prot:TRPG_SALTY   RecName: Full=Anthranilate synthase component II;         EC=4.1.3.27;Includes:  RecName: Full=Glutamine amidotransferase;Includes:  RecName: Full=Anthranilate phosphoribosyltransferase;           EC=2.4.2.18;

Homologs  Archaea  62/68 : Bacteria  779/915 : Eukaryota  121/199 : Viruses  0/175   --->[See Alignment]
a.46.2c.23.16c.27.1
:531 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   2->193 1i1qB PDBj e-104 98.9 %
:BLT:PDB   199->530 1khdB PDBj e-129 76.2 %
:RPS:PDB   1->163 3dkyE PDBj 1e-43 11.8 %
:RPS:PDB   199->529 2bpqA PDBj 1e-63 23.7 %
:RPS:SCOP  2->193 1i1qB  c.23.16.1 * 4e-32 97.8 %
:RPS:SCOP  199->267 1kgzA1  a.46.2.1 * 7e-13 59.4 %
:RPS:SCOP  268->530 1kgzA2  c.27.1.1 * 5e-83 71.8 %
:HMM:SCOP  1->190 1qdlB_ c.23.16.1 * 1e-49 36.9 %
:HMM:SCOP  198->267 1o17A1 a.46.2.1 * 1.1e-16 37.1 %
:HMM:SCOP  268->530 1khdA2 c.27.1.1 * 9.2e-89 48.3 %
:RPS:PFM   6->183 PF00117 * GATase 4e-22 38.2 %
:RPS:PFM   203->252 PF02885 * Glycos_trans_3N 1e-05 34.0 %
:RPS:PFM   278->481 PF00591 * Glycos_transf_3 2e-48 50.2 %
:HMM:PFM   272->521 PF00591 * Glycos_transf_3 7.5e-105 53.6 250/254  
:HMM:PFM   5->187 PF00117 * GATase 3.3e-48 36.5 181/192  
:HMM:PFM   199->263 PF02885 * Glycos_trans_3N 1.5e-20 33.8 65/66  
:BLT:SWISS 1->531 TRPG_SALTY 0.0 99.6 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF69017.1 GT:GENE trpD GT:PRODUCT anthranilate synthase, component II GT:DATABASE GIB00763CH01 GT:ORG sent8 GB:ACCESSION GIB00763CH01 GB:LOCATION 1867923..1869518 GB:FROM 1867923 GB:TO 1869518 GB:DIRECTION + GB:GENE trpD GB:PRODUCT anthranilate synthase, component II GB:NOTE identified by match to protein family HMM PF00117; match to protein family HMM PF00591; match to protein family HMM PF02885; match to protein family HMM TIGR00566; match to protein family HMM TIGR01245 GB:PROTEIN_ID ACF69017.1 GB:DB_XREF GI:194408798 GB:GENE:GENE trpD LENGTH 531 SQ:AASEQ MADILLLDNIDSFTWNLADQLRTNGHNVVIYRNHIPAQTLIDRLATMKNPVLMLSPGPGIPSEAGCMPELLTRLRGKLPIIGICLGHQAIVEAYGGYVGQAGEILHGKASSIEHDGQAMFAGLANPLPVARYHSLVGSNVPAGLTINAHFNGMVMAVRHDADRVCGFQFHPESILTTQGARLLEQTLAWAQQKLEPTNTLQPILEKLYQAQTLTQQESHQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRPEYLFADIVGTGGDGSNSINISTASAFVAAACGLKVAKHGNRSVSSKSGSSDLLAAFGINLDMNADKSRQALDELGVCFLFAPKYHTGFRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGVYSPELVLPIAETLRVLGYQRAAVVHSGGMDEVSLHAPTIVAELHDGEIKSYQLTAEDFGLTPYHQDQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHGQEDLKANAQTVLDVLRNGTAYDRVTALAARG GT:EXON 1|1-531:0| SW:ID TRPG_SALTY SW:DE RecName: Full=Anthranilate synthase component II; EC=4.1.3.27;Includes: RecName: Full=Glutamine amidotransferase;Includes: RecName: Full=Anthranilate phosphoribosyltransferase; EC=2.4.2.18; SW:GN Name=trpD; Synonyms=trpGD; OrderedLocusNames=STM1724; SW:KW 3D-structure; Amino-acid biosynthesis;Aromatic amino acid biosynthesis; Complete proteome;Glutamine amidotransferase; Glycosyltransferase; Lyase;Multifunctional enzyme; Transferase; Tryptophan biosynthesis. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->531|TRPG_SALTY|0.0|99.6|531/531| GO:SWS:NREP 8 GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0009073|"GO:aromatic amino acid family biosynthetic process"|Aromatic amino acid biosynthesis| GO:SWS GO:0006541|"GO:glutamine metabolic process"|Glutamine amidotransferase| GO:SWS GO:0016757|"GO:transferase activity, transferring glycosyl groups"|Glycosyltransferase| GO:SWS GO:0016829|"GO:lyase activity"|Lyase| GO:SWS GO:0003824|"GO:catalytic activity"|Multifunctional enzyme| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| GO:SWS GO:0000162|"GO:tryptophan biosynthetic process"|Tryptophan biosynthesis| SEG 253->264|agaatallenaa| SEG 311->319|svssksgss| SEG 482->493|aaheaavaanva| BL:PDB:NREP 2 BL:PDB:REP 2->193|1i1qB|e-104|98.9|186/186| BL:PDB:REP 199->530|1khdB|e-129|76.2|328/328| RP:PDB:NREP 2 RP:PDB:REP 1->163|3dkyE|1e-43|11.8|161/180| RP:PDB:REP 199->529|2bpqA|1e-63|23.7|329/344| RP:PFM:NREP 3 RP:PFM:REP 6->183|PF00117|4e-22|38.2|173/185|GATase| RP:PFM:REP 203->252|PF02885|1e-05|34.0|50/65|Glycos_trans_3N| RP:PFM:REP 278->481|PF00591|2e-48|50.2|203/252|Glycos_transf_3| HM:PFM:NREP 3 HM:PFM:REP 272->521|PF00591|7.5e-105|53.6|250/254|Glycos_transf_3| HM:PFM:REP 5->187|PF00117|3.3e-48|36.5|181/192|GATase| HM:PFM:REP 199->263|PF02885|1.5e-20|33.8|65/66|Glycos_trans_3N| GO:PFM:NREP 3 GO:PFM GO:0003824|"GO:catalytic activity"|PF00117|IPR000991| GO:PFM GO:0008152|"GO:metabolic process"|PF00591|IPR000312| GO:PFM GO:0016757|"GO:transferase activity, transferring glycosyl groups"|PF00591|IPR000312| RP:SCP:NREP 3 RP:SCP:REP 2->193|1i1qB|4e-32|97.8|186/186|c.23.16.1| RP:SCP:REP 199->267|1kgzA1|7e-13|59.4|69/69|a.46.2.1| RP:SCP:REP 268->530|1kgzA2|5e-83|71.8|259/259|c.27.1.1| HM:SCP:REP 1->190|1qdlB_|1e-49|36.9|187/195|c.23.16.1|1/1|Class I glutamine amidotransferase-like| HM:SCP:REP 198->267|1o17A1|1.1e-16|37.1|70/70|a.46.2.1|1/1|Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain| HM:SCP:REP 268->530|1khdA2|9.2e-89|48.3|263/0|c.27.1.1|1/1|Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain| OP:NHOMO 2317 OP:NHOMOORG 962 OP:PATTERN 22-2--2222222222-22222224223333333333322332222221222233311311222--23 2322444444433332223-2322222222223333445432322222322222223211222222345343333333----22222322222221-222-223222232--------11----132232233223322223342222532232222222222233346532223222223224444432-22233333333133333322222233322243433333332313332333333333333333----11-----22--11----2-33311111112222222222222211111111111112--222----33-23----------212211112-2-122223335322--323223-212332222-----334224443242222222222222-33333333223-2222222222223223222222222222222222222213223-----------------------------32222322222222222322222222222222222222222223222222222332222222222222222222222-45333231233331222222222222233442111-22222232133333323223223333223333333334433333333333331-2223212-11322333232222222222-2222222222222222222222434432221222222222222322222223-331333313333331311-1133332223333323313333313322222323332233332224222222222311333331233333333333333223232222233222221332222111-1---------------------------------2111-111222 ------1-----2332322222223223323333332333333222223332342232222132223213233332222233333233-36233332223323232-15----------------------------------------------------------------1-3322S2333343462853253433 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 530 STR:RPRED 99.8 SQ:SECSTR HHHHHHHTcccEEEccccccccHTEEEEEEccccccHHHHHHHHHHHHccEEcccHHHHHHHTTTccHHHHHTTcccccTTccEEETTccGGGGcccHHHHHHHHHHHHHHHHHTTcccHHHHHHHHHHHHHHHTcHHHHHHHHTTTHHHHHHHHHHHHHHTTEEEEcccTTcTTcTTHHHHHHHHHHHHHHHHccc#cHHHHHHHHHTTccccTTHHHHHHHHHHTTcccHHHHHHHHHHHHHccccHHHHHHHHHHHHHHcccccTcTTccEEEEEcccTTcccHHHHHHHHHHHHHTTccEEEEEccGGGcccccHHHHHHTTccccccHHHHHHHHHHHcEEEEEHHHHccccTTHHHHHHHHccccGGGTcGGGccTTcccEEEEEcccHHHHHHHHHHHHHTTHcEEEEEETTccccccccccEEEEEEETTEEEEEEEcGGGGTcccccGGGGccccHHHHHHHHHHHHTTccHHHHHHHHHHHHTTcTTccHHHHHHHHHHHHHHHHHTcHHHHHHHHHHHcc PSIPRED ccEEEEEEcccHHHHHHHHHHHHccccEEEEEccccccccHHHHHcccccEEEEccccccHHHccccHHHHHHHcccccEEEEcHHHHHHHHHcccEEEEccccccccEEEEEEccccEEccccccEEEEEcccEEEccccccEEEEEEEccEEEEEEEccccEEEEEcccccccccHHHHHHHHHHHHHHHHccccccHHHHHHHHHHcccccHHHHHHHHHHHHcccccHHHHHHHHHHHHHccccHHHHHHHHHHHHHHccccccccccEEEEEccccccccccccHHHHHHHHHHccccEEEEccccccccccHHHHHHHccccccccHHHHHHHHHHccEEEEEHHHccHHHHHHHHHHHHcccccHHHHHHHHcccccccEEEEEEccHHHHHHHHHHHHHccccEEEEEccccEEEEcccccEEEEEEEccEEEEEEEEHHHHccccccHHHcccccHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHccHHHHHHHHHHccc //