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Streptococcus pneumoniae G54 (spne4)
Gene : ACF54907.1
DDBJ      :             acetolactate synthase large subunit
Swiss-Prot:             

Homologs  Archaea  56/68 : Bacteria  764/915 : Eukaryota  180/199 : Viruses  0/175   --->[See Alignment]
c.31.1c.36.1c.92.2
:566 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   1->560 3ea4A PDBj e-125 43.6 %
:RPS:PDB   11->538 1bfdA PDBj e-120 25.2 %
:RPS:SCOP  2->521 1fp4B  c.92.2.3 * 3e-85 10.2 %
:HMM:SCOP  10->193 1ybhA2 c.36.1.5 * 1.1e-60 43.1 %
:HMM:SCOP  191->361 1jscA1 c.31.1.3 * 4e-61 49.1 %
:HMM:SCOP  367->560 2djiA3 c.36.1.9 * 6.1e-62 45.8 %
:RPS:PFM   11->171 PF02776 * TPP_enzyme_N 4e-43 49.7 %
:RPS:PFM   213->335 PF00205 * TPP_enzyme_M 1e-35 56.1 %
:RPS:PFM   409->537 PF02775 * TPP_enzyme_C 1e-25 45.7 %
:HMM:PFM   11->176 PF02776 * TPP_enzyme_N 2e-60 45.2 166/172  
:HMM:PFM   200->335 PF00205 * TPP_enzyme_M 9.3e-49 50.0 136/137  
:HMM:PFM   391->538 PF02775 * TPP_enzyme_C 1.1e-47 46.3 147/150  
:BLT:SWISS 1->564 ILVB_LACLA 0.0 63.5 %
:PROS 428->447|PS00187|TPP_ENZYMES
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF54907.1 GT:GENE ACF54907.1 GT:PRODUCT acetolactate synthase large subunit GT:DATABASE GIB00761CH01 GT:ORG spne4 GB:ACCESSION GIB00761CH01 GB:LOCATION 397089..398789 GB:FROM 397089 GB:TO 398789 GB:DIRECTION + GB:PRODUCT acetolactate synthase large subunit GB:NOTE identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118 GB:PROTEIN_ID ACF54907.1 GB:DB_XREF GI:194356459 LENGTH 566 SQ:AASEQ MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIYNFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPLLVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRPGPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAGGGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTEADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQMLLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDVGQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQMTNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAYGIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA GT:EXON 1|1-566:0| BL:SWS:NREP 1 BL:SWS:REP 1->564|ILVB_LACLA|0.0|63.5|564/575| PROS 428->447|PS00187|TPP_ENZYMES|PDOC00166| SEG 199->212|qikkilkqlskakk| BL:PDB:NREP 1 BL:PDB:REP 1->560|3ea4A|e-125|43.6|555/581| RP:PDB:NREP 1 RP:PDB:REP 11->538|1bfdA|e-120|25.2|515/523| RP:PFM:NREP 3 RP:PFM:REP 11->171|PF02776|4e-43|49.7|161/170|TPP_enzyme_N| RP:PFM:REP 213->335|PF00205|1e-35|56.1|123/138|TPP_enzyme_M| RP:PFM:REP 409->537|PF02775|1e-25|45.7|129/139|TPP_enzyme_C| HM:PFM:NREP 3 HM:PFM:REP 11->176|PF02776|2e-60|45.2|166/172|TPP_enzyme_N| HM:PFM:REP 200->335|PF00205|9.3e-49|50.0|136/137|TPP_enzyme_M| HM:PFM:REP 391->538|PF02775|1.1e-47|46.3|147/150|TPP_enzyme_C| GO:PFM:NREP 5 GO:PFM GO:0030976|"GO:thiamin pyrophosphate binding"|PF02776|IPR012001| GO:PFM GO:0000287|"GO:magnesium ion binding"|PF00205|IPR012000| GO:PFM GO:0030976|"GO:thiamin pyrophosphate binding"|PF00205|IPR012000| GO:PFM GO:0003824|"GO:catalytic activity"|PF02775|IPR011766| GO:PFM GO:0030976|"GO:thiamin pyrophosphate binding"|PF02775|IPR011766| RP:SCP:NREP 1 RP:SCP:REP 2->521|1fp4B|3e-85|10.2|500/522|c.92.2.3| HM:SCP:REP 10->193|1ybhA2|1.1e-60|43.1|181/0|c.36.1.5|1/2|Thiamin diphosphate-binding fold (THDP-binding)| HM:SCP:REP 191->361|1jscA1|4e-61|49.1|171/0|c.31.1.3|1/1|DHS-like NAD/FAD-binding domain| HM:SCP:REP 367->560|2djiA3|6.1e-62|45.8|192/0|c.36.1.9|2/2|Thiamin diphosphate-binding fold (THDP-binding)| OP:NHOMO 3389 OP:NHOMOORG 1000 OP:PATTERN 11-1--6665566674-31221143--21122243222222221312213343211-----2421-11 4362942233323257A55-53337E545556455555EG2225243-232196754311635255C98621222111-211811111223112--111-1111142211---------------21111111111222331111834524432211113111222333721111111211111211111-134555554571465536334434545235242-4444432534444444444444434444122145112-27622553331344231111---22222222222222-------------221222111122135-------5-42133111-112--2122165222121221112--1-112222-11-124CAB2149457633333332316-66855A59772-644346B775896413168A42367685555555542222332-----------------------------3335226DA8899BAA986666AADE999957A8H89A824654333228355B73333111311111111112422-A22312234333412213112443222352521111111111-1-------1111221322241312222332422322222323233-1-311111111155553555666576766-6646767656666665664878763357566556667668664965666651-75555554555511---1---112232762222222-22213222333332312442A99949454588633333----1---313253333322222332222222211111111331132------------------------111----------11--1-111122 ----22--21----254425554B69833222222224142442333324235C1124232242342732573424523432222124-23242221111112522-25-4232222--11121242618K2-32412122-152121122-1421123374163211122235121118111235125244223111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 565 STR:RPRED 99.8 SQ:SECSTR ccEEcTTccEcHHHHHHHHHHHTTccEEEEcccGGGHHHHTTccHHTTcEEEEcccHHHHHHHHHHHHHHHTccEEEEEEHHHHHHHTHHHHHHHHHHTccEEEEEEEccHHHHTTTcTccTTGGGTTTTcccEEEccccGGGHHHHHHHHHHHHHccccccEEEEEEGGGTTccccGcGGGGGTTccccccccccHHHHHHHHHHHHHccccEEEEcHHHHHHTcHHHHHHHHHHHTccEEEcccccccccTTcTTEEEEcccGcHHHHHHHHTTccEEEEEcccTTcccccccccccTTcEEEEEEccHHHHHHccccEEEEEccHHHHHHHHHcccccHHHccccccccccccccccccccccccccHHHHHHHHHHHccTTcEEEEEcGGGHHHHHHHcccccTTcEEEcTTccccccHHHHHHHHHHHcTTccEEEEEEHHHHTTTGGGHHHHHHHTcccEEEEEEccccHHHHHHHHHTTccccccccccccccHHHHHHHTTcEEEEEccHHHHHHHHHHHHccccEEEEEEcccccccTTTTcTTccGGGcTTcccH# DISOP:02AL 1-10,565-567| PSIPRED cccccccccccHHHHHHHHHHHccccEEEEcccccHHHHHHHHHHccccEEEEcccHHHHHHHHHHHHHHHccEEEEEEcccHHHHHHHHHHHHHHHHcccEEEEEccccHHHccccccccccHHHHHHHHccEEEEcccHHHHHHHHHHHHHHHHcccccEEEEEEccHHHHcccccccccccccccccccccccHHHHHHHHHHHHHccccEEEEccccccHHHHHHHHHHHHHHcccEEEcHHHccccccccccccccccccccHHHHHHHHHccEEEEEcccccccccccHHHccccccEEEEEccHHHHccccccccEEEccHHHHHHHHHHccccccccHHHHHHHHHHHHHccccccccccccHHHHHHHHHHHcccccEEEEcccHHHHHHHHccccccccEEEcccccccHHHHHHHHHHHHHHccccEEEEEEccHHHHHcHHHHHHHHHccccEEEEEEEccccHHHHHHHHHccccccccccccccccHHHHHHHccccEEEEccHHHHHHHHHHHHccccEEEEEEEcccccccccccccccHHHHccccccc //