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Streptococcus pneumoniae G54 (spne4)
Gene : ACF55591.1
DDBJ      :             penicillin-binding protein 1A
Swiss-Prot:PBPA_STRPN   RecName: Full=Penicillin-binding protein 1A;         Short=PBP-1A;

Homologs  Archaea  0/68 : Bacteria  829/915 : Eukaryota  8/199 : Viruses  0/175   --->[See Alignment]
d.2.1e.3.1
:719 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   66->252 2oqoA PDBj 1e-37 43.0 %
:BLT:PDB   267->650 2c6wB PDBj 0.0 92.2 %
:RPS:PDB   69->252 3d3hA PDBj 5e-60 47.4 %
:RPS:PDB   267->650 2c6wB PDBj 8e-70 90.1 %
:RPS:SCOP  46->274 2oluA1  d.2.1.10 * 8e-64 40.5 %
:RPS:SCOP  266->650 2c5wB1  e.3.1.1 * 1e-70 89.6 %
:HMM:SCOP  266->650 2c5wB1 e.3.1.1 * 1.4e-92 29.9 %
:RPS:PFM   62->236 PF00912 * Transgly 7e-45 50.6 %
:RPS:PFM   330->621 PF00905 * Transpeptidase 5e-27 38.5 %
:HMM:PFM   60->237 PF00912 * Transgly 2.9e-64 47.4 175/178  
:HMM:PFM   331->622 PF00905 * Transpeptidase 1.2e-34 29.3 276/304  
:BLT:SWISS 1->653 PBPA_STRPN 0.0 92.6 %
:TM
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF55591.1 GT:GENE ACF55591.1 GT:PRODUCT penicillin-binding protein 1A GT:DATABASE GIB00761CH01 GT:ORG spne4 GB:ACCESSION GIB00761CH01 GB:LOCATION complement(327805..329964) GB:FROM 327805 GB:TO 329964 GB:DIRECTION - GB:PRODUCT penicillin-binding protein 1A GB:NOTE identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 GB:PROTEIN_ID ACF55591.1 GB:DB_XREF GI:194357143 LENGTH 719 SQ:AASEQ MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSESKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGIDTIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQKATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLRELSLPQLALLAGMPQAPNQYDPYSHPEAALDRRNLVLSEMKGQGYISAEQYEKAINTPITDGLQSLKSVNSYPAYMDNYLKEVIDQVEQETGYNLLTTGMDVYTNVDQEAQKHLWDIYNSDQYVSYPDDDLQVASTVVDVSNGKVIAQLGARHQASNVSFGTNQAVETNRDWGSTMKPITDYAPAIEYGVYDSTATMVNDIPYNYPGTSTPVYNWDRAYFGNITLQYALQQSRNVPAVETLNKVGLDRAKNFLNGLGIDYPDMHYSNAISSNTTESNKQYGASSEKMAAAFAAFANGGIYHKPMYINKIVFSDGSEKEFSDAGTRAMKETTAYMMTEMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDEEIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTYLSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSSSTTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP GT:EXON 1|1-719:0| SW:ID PBPA_STRPN SW:DE RecName: Full=Penicillin-binding protein 1A; Short=PBP-1A; SW:GN Name=ponA; OrderedLocusNames=SP_0369; SW:KW 3D-structure; Antibiotic resistance; Cell shape;Cell wall biogenesis/degradation; Complete proteome;Multifunctional enzyme; Peptidoglycan synthesis; Secreted. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->653|PBPA_STRPN|0.0|92.6|653/719| GO:SWS:NREP 6 GO:SWS GO:0046677|"GO:response to antibiotic"|Antibiotic resistance| GO:SWS GO:0008360|"GO:regulation of cell shape"|Cell shape| GO:SWS GO:0007047|"GO:cellular cell wall organization"|Cell wall biogenesis/degradation| GO:SWS GO:0003824|"GO:catalytic activity"|Multifunctional enzyme| GO:SWS GO:0009252|"GO:peptidoglycan biosynthetic process"|Peptidoglycan synthesis| GO:SWS GO:0005576|"GO:extracellular region"|Secreted| TM:NTM 1 TM:REGION 12->34| SEG 484->491|aaafaafa| SEG 654->718|stwsspapqqppstessssssdsstsqsssttpstnnstttnpnnntqqsnttpdqqnqnpqpaq| BL:PDB:NREP 2 BL:PDB:REP 66->252|2oqoA|1e-37|43.0|179/181| BL:PDB:REP 267->650|2c6wB|0.0|92.2|384/384| RP:PDB:NREP 2 RP:PDB:REP 69->252|3d3hA|5e-60|47.4|173/174| RP:PDB:REP 267->650|2c6wB|8e-70|90.1|384/384| RP:PFM:NREP 2 RP:PFM:REP 62->236|PF00912|7e-45|50.6|172/178|Transgly| RP:PFM:REP 330->621|PF00905|5e-27|38.5|270/289|Transpeptidase| HM:PFM:NREP 2 HM:PFM:REP 60->237|PF00912|2.9e-64|47.4|175/178|Transgly| HM:PFM:REP 331->622|PF00905|1.2e-34|29.3|276/304|Transpeptidase| GO:PFM:NREP 5 GO:PFM GO:0003824|"GO:catalytic activity"|PF00912|IPR001264| GO:PFM GO:0009252|"GO:peptidoglycan biosynthetic process"|PF00912|IPR001264| GO:PFM GO:0009274|"GO:peptidoglycan-based cell wall"|PF00912|IPR001264| GO:PFM GO:0008658|"GO:penicillin binding"|PF00905|IPR001460| GO:PFM GO:0009273|"GO:peptidoglycan-based cell wall biogenesis"|PF00905|IPR001460| RP:SCP:NREP 2 RP:SCP:REP 46->274|2oluA1|8e-64|40.5|205/208|d.2.1.10| RP:SCP:REP 266->650|2c5wB1|1e-70|89.6|385/385|e.3.1.1| HM:SCP:REP 266->650|2c5wB1|1.4e-92|29.9|385/0|e.3.1.1|1/1|beta-lactamase/transpeptidase-like| OP:NHOMO 2438 OP:NHOMOORG 837 OP:PATTERN -------------------------------------------------------------------- 333-322222222222222-23222322222233333344233322212323232112115522324846321222221131311111333214111--23443236515---------------2222212232222233---215343334223312122243224673111-11111-11232111124346666676666666666455446674544433222222443333333333333333333332223422324222233332222333333333333333333333333333333333333343333333331212211111212221211111131211322213333222521111212144-766422222454444445354533333333334-6666776565414444556555673434423343442451111111111112335------------2222122211112----1433424444468878655554664455552675457671222243333353442333222332222222222222453532133212222133333333334444434122131111121211111111111122443233322233444333233332422322--11213-1-11144323434444444444-4444444444444344444444334444444344444444443443332342133444444444411131111122223542422233313332222423333333333333334335444443444---------122242222233222444444433333331-136666661111111111--------------------------1-11111111--3 -------------1-----------------------------------------------------------------------------------------------------------------------------------------------------1--------------11-----1--3--1--1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 609 STR:RPRED 84.7 SQ:SECSTR ############################################ccccccccEEEEcTTccEEEEEcccccccccGGGccHHHHHHHHHHHcGGGTTcccccHHHHHHTTTTTTTcccccccccHHHHHHHHHccccccccccccHHHHHHHHHHHHHHHccHHHHHHHHHHHccccTTcccHHHHHHHHTccccTTccHHHHHHHHHGGGcHHHHcTTTcHHHHHHHHHHHHHHHHHTTcccHHHHHHHTTcccGGGcccTTGGGcccccTTGGGHHHHHHHHHHcHHHHTTcTcEEEEcccHHHHHHHHHHHHcHHccccccTTEEEEEEEEETTTccEEEEEccTTccTTcTTTcccTTTccEEcGGGGHHHHTHHHHHHHcccccTTcEEEcccccccccccccccTTcccccEEEHHHHHHTTcHHHHHHHHHHHHHHccTTHHHHHHHHTTccccccGccHHHHTTcTTcEEcHHHHHHHHHHHTTTcEEEccccEEEEEcccccEEEccccEEEcccHHHHHHHHHHHHTTccTTcTTTTcccccccEEEEEEEEccTTHHHHTTccTTEEEEEEEEEEEcccEEEEEEEEEGGTTcEEHHHHHTHHHHHHHHHHHHHccccccccccccTTEEEETTEEEEcccc################################################################## DISOP:02AL 1-3,656-720| PSIPRED ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHcccccEEEEEccccEEEEEccccEEEEcHHHccHHHHHHHHHHHHccccccccccHHHHHHHHHHHHHccccccccHHHHHHHHHHHcccccccccHHHHHHHHHHHHHHHHHHcHHHHHHHHcccccccccHHHHHHHHHHHHcccHHHccHHHHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHcccccccccccccHHHHHHHHHHHHHHHHHHHHHHHHcccccEEEEcccHHHHHHHHHHHHHHHHHccccccccEEEEEEEccccEEEEEEcccccccccccccccccccccccHHHHHHHHHHHHHHHccccccccEEEccccEEEccEEEEEEEccccccccccHHHHHHHccHHHHHHHHHHHcHHHHHHHHHHHccccccccccccccccHHHccccccccHHHHHHHHHHHHcccEEEccEEEEEEEcccccEEEccccccccccHHHHHHHHHHHHHHHHcccccccccccccEEEEEcccccccccccccccccccccccEEEEEEcccEEEEEEEEcccccccccccccHHHHHHHHHHHHHHHccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccc //