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Streptococcus pneumoniae G54 (spne4)
Gene : ACF56111.1
DDBJ      :             dihydrofolate folylpolyglutamate synthetase
Swiss-Prot:             

Homologs  Archaea  11/68 : Bacteria  847/915 : Eukaryota  181/199 : Viruses  0/175   --->[See Alignment]
c.59.1c.72.2
:418 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   5->412 1jbwA PDBj 4e-43 32.5 %
:RPS:PDB   21->413 2am1A PDBj 3e-39 14.4 %
:RPS:SCOP  1->286 1o5zA2  c.72.2.2 * 9e-50 28.4 %
:RPS:SCOP  288->412 1o5zA1  c.59.1.2 * 5e-12 22.8 %
:HMM:SCOP  1->287 1o5zA2 c.72.2.2 * 3.3e-91 44.5 %
:HMM:SCOP  288->411 1o5zA1 c.59.1.2 * 1.7e-19 37.5 %
:RPS:PFM   153->214 PF08245 * Mur_ligase_M 3e-06 50.9 %
:HMM:PFM   44->258 PF08245 * Mur_ligase_M 3.1e-16 29.3 167/188  
:HMM:PFM   286->347 PF02875 * Mur_ligase_C 0.00048 24.6 61/91  
:BLT:SWISS 5->408 FOLC_BACSU 2e-54 35.6 %
:PROS 139->154|PS01012|FOLYLPOLYGLU_SYNT_2
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF56111.1 GT:GENE ACF56111.1 GT:PRODUCT dihydrofolate folylpolyglutamate synthetase GT:DATABASE GIB00761CH01 GT:ORG spne4 GB:ACCESSION GIB00761CH01 GB:LOCATION 182863..184119 GB:FROM 182863 GB:TO 184119 GB:DIRECTION + GB:PRODUCT dihydrofolate folylpolyglutamate synthetase GB:NOTE identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 GB:PROTEIN_ID ACF56111.1 GB:DB_XREF GI:194357663 LENGTH 418 SQ:AASEQ MCMFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTGTNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKEMEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVITSIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQAGQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVRKALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKDYQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDLLFVTGSLYFISEVRGYLLDREQIN GT:EXON 1|1-418:0| BL:SWS:NREP 1 BL:SWS:REP 5->408|FOLC_BACSU|2e-54|35.6|396/430| PROS 139->154|PS01012|FOLYLPOLYGLU_SYNT_2|PDOC00773| SEG 134->149|evdlvllevgigglld| SEG 232->242|sssllnlsqln| BL:PDB:NREP 1 BL:PDB:REP 5->412|1jbwA|4e-43|32.5|391/409| RP:PDB:NREP 1 RP:PDB:REP 21->413|2am1A|3e-39|14.4|341/442| RP:PFM:NREP 1 RP:PFM:REP 153->214|PF08245|3e-06|50.9|53/187|Mur_ligase_M| HM:PFM:NREP 2 HM:PFM:REP 44->258|PF08245|3.1e-16|29.3|167/188|Mur_ligase_M| HM:PFM:REP 286->347|PF02875|0.00048|24.6|61/91|Mur_ligase_C| GO:PFM:NREP 2 GO:PFM GO:0005524|"GO:ATP binding"|PF08245|IPR013221| GO:PFM GO:0009058|"GO:biosynthetic process"|PF08245|IPR013221| RP:SCP:NREP 2 RP:SCP:REP 1->286|1o5zA2|9e-50|28.4|271/284|c.72.2.2| RP:SCP:REP 288->412|1o5zA1|5e-12|22.8|123/137|c.59.1.2| HM:SCP:REP 1->287|1o5zA2|3.3e-91|44.5|283/296|c.72.2.2|1/1|MurD-like peptide ligases, catalytic domain| HM:SCP:REP 288->411|1o5zA1|1.7e-19|37.5|112/137|c.59.1.2|1/1|MurD-like peptide ligases, peptide-binding domain| OP:NHOMO 1325 OP:NHOMOORG 1039 OP:PATTERN ------------------------21111111-----------------------------111---- 111-111111111111111-11111-1111111111111111111111111111111111111111111111111111111111111111111111---11111111111--------------111-1-111111111111111211112211111111111111211111111111111112212211121111111111111111111111111111121111111111111111111111111111111111211221212222112113211111112111222222222222222222222222222222222222111211111111111111111111111111111111111111111111212111111111111111111111122211111111111-21111111111121111111111111112111111111111111111-111111111111111111111111111111111-111111-1111111111111111111111111-1111111111111121111111111111111111111111111111-11111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111-11111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--111111111111111111111111111111111111111111111111111111111111111-11111111111----11--------111--1-1---1--------1-------1211111111121 11--111-311-2223322244334323342224333323332131543332422322232122222222222222313322222222-13232232122222223-1-12111-1211-11112-13-8B2--11-1-11113-1111111-11111224212111221133111112A312223226266212222- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 413 STR:RPRED 98.8 SQ:SECSTR HHHHHHHHcTTHHHHHHHHTcHHHHHHHHHHHHHHHHccEEEEEEcccccccHHHHHHHHTTTcccccEEEEEEccTTcccTTHHHHHHHTcTTccEEEEEccccccHHHHHHcTTHHHHHEEGGGGccccHTTccEEEEccHHHHHTTTHHHHcccEEEEccccccccTTcccHHHHHHHHHGGGTTcTTcEEEEEccGGGGGGcccccEEEEEcTTccccEEEEEccEEEEETTcccEEEEccccHHHHHHHHHHHHHHHTHTccHHHTccHHHHHHHGGGccccccccEEccEEEEEcccccHHHHHHHHHHTTccccccEEEEEEEccHHHHHHHGGGccTTTccEEHHHHHHHHHccTTcEEEEEccccccTHHHHHHHHHHHccTTEEEEEEccccHHHHHHHHHHc##### DISOP:02AL 1-1,418-419| PSIPRED ccHHHHHHHHHHHHcccccccHHHHHHHHHHccccHHccEEEEEEccccHHHHHHHHHHHHHHccccEEEEEcccccccccEEEEccEEccHHHHHHHHHHHHHHHHHcccccccccHHHHHHHHHHHHHHHccccEEEEEcccccHHHHcccccccEEEEccccHHHHHHHcccHHHHHHHHHHHHccccEEEEEcccHHHHHHHHHHHHHccccEEEEccEEEEEEEEEEccccccccccccccccccHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHccccccEEEEccEEEEEccccHHHHHHHHHHHHHHHcccccEEEEEcccccccHHHHHHHHHHHccEEEEEccccccHHcccHHHcccEEEEccHHHHHHHHHHHcccccEEEEEccHHHHHHHHHHHHHccccc //