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Streptococcus pneumoniae G54 (spne4)
Gene : ciaH
DDBJ      :ciaH         CiaH histidine kinase TCS05
Swiss-Prot:CIAH_STRR6   RecName: Full=Sensor protein ciaH;         EC=2.7.13.3;

Homologs  Archaea  24/68 : Bacteria  821/915 : Eukaryota  105/199 : Viruses  1/175   --->[See Alignment]
a.30.2d.122.1d.123.1
:444 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   220->434 3dgeA PDBj 2e-21 29.9 %
:RPS:PDB   212->434 3dgeA PDBj 3e-25 26.0 %
:RPS:SCOP  211->404 1f51A  d.123.1.1 * 5e-20 15.7 %
:HMM:SCOP  198->283 2c2aA1 a.30.2.1 * 3.2e-10 29.1 %
:HMM:SCOP  280->442 1gkzA2 d.122.1.4 * 6e-35 27.8 %
:RPS:PFM   331->430 PF02518 * HATPase_c 2e-17 39.0 %
:HMM:PFM   327->434 PF02518 * HATPase_c 3e-29 40.2 107/111  
:HMM:PFM   217->283 PF00512 * HisKA 3.7e-12 34.3 67/68  
:HMM:PFM   59->136 PF07209 * DUF1415 0.001 19.2 78/174  
:HMM:PFM   185->211 PF00672 * HAMP 0.00071 37.0 27/70  
:BLT:SWISS 1->444 CIAH_STRR6 0.0 100.0 %
:TM

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF56115.1 GT:GENE ciaH GT:PRODUCT CiaH histidine kinase TCS05 GT:DATABASE GIB00761CH01 GT:ORG spne4 GB:ACCESSION GIB00761CH01 GB:LOCATION 707463..708797 GB:FROM 707463 GB:TO 708797 GB:DIRECTION + GB:GENE ciaH GB:PRODUCT CiaH histidine kinase TCS05 GB:NOTE Guenzi Mol Microbiol. 1994 12(3):505-15.; identified by match to protein family HMM PF00512; match to protein family HMM PF02518 GB:PROTEIN_ID ACF56115.1 GB:DB_XREF GI:194357667 GB:GENE:GENE ciaH LENGTH 444 SQ:AASEQ MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLYTSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFDKDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTNIKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQSFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLNLARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQLMTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKARTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK GT:EXON 1|1-444:0| SW:ID CIAH_STRR6 SW:DE RecName: Full=Sensor protein ciaH; EC=2.7.13.3; SW:GN Name=ciaH; OrderedLocusNames=spr0708; SW:KW ATP-binding; Cell membrane; Competence; Complete proteome; Kinase;Membrane; Nucleotide-binding; Phosphoprotein; Transferase;Transmembrane; Two-component regulatory system. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->444|CIAH_STRR6|0.0|100.0|444/444| GO:SWS:NREP 9 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005886|"GO:plasma membrane"|Cell membrane| GO:SWS GO:0030420|"GO:establishment of competence for transformation"|Competence| GO:SWS GO:0016301|"GO:kinase activity"|Kinase| GO:SWS GO:0016020|"GO:membrane"|Membrane| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| GO:SWS GO:0016021|"GO:integral to membrane"|Transmembrane| GO:SWS GO:0000160|"GO:two-component signal transduction system (phosphorelay)"|Two-component regulatory system| TM:NTM 2 TM:REGION 21->43| TM:REGION 182->204| BL:PDB:NREP 1 BL:PDB:REP 220->434|3dgeA|2e-21|29.9|214/237| RP:PDB:NREP 1 RP:PDB:REP 212->434|3dgeA|3e-25|26.0|223/237| RP:PFM:NREP 1 RP:PFM:REP 331->430|PF02518|2e-17|39.0|100/112|HATPase_c| HM:PFM:NREP 4 HM:PFM:REP 327->434|PF02518|3e-29|40.2|107/111|HATPase_c| HM:PFM:REP 217->283|PF00512|3.7e-12|34.3|67/68|HisKA| HM:PFM:REP 59->136|PF07209|0.001|19.2|78/174|DUF1415| HM:PFM:REP 185->211|PF00672|0.00071|37.0|27/70|HAMP| GO:PFM:NREP 1 GO:PFM GO:0005524|"GO:ATP binding"|PF02518|IPR003594| RP:SCP:NREP 1 RP:SCP:REP 211->404|1f51A|5e-20|15.7|172/181|d.123.1.1| HM:SCP:REP 198->283|2c2aA1|3.2e-10|29.1|86/0|a.30.2.1|1/1|Homodimeric domain of signal transducing histidine kinase| HM:SCP:REP 280->442|1gkzA2|6e-35|27.8|162/193|d.122.1.4|1/1|ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase| OP:NHOMO 9809 OP:NHOMOORG 951 OP:PATTERN -----------------------2B22-2524---1-122224-3-297KF38--------------3 4HP2E45655643437755-5A3387555556B99A34634745444247535783351158I2958A896222243355D8612244TTjW-b213--C8S7HAaUeLd--------------2213A4427285UWVJID57b2pYhfSSFDF892-2453HRATws*H2212-114-3-1A953334299ENNPNPKPODOORPPLEECB9CNOV6ADM7IE977987ZX6778787777777776554576769963446565599654665575ABA666653355555555555444444444544453333133365VEKtNNMUQOQLNKDTSR9CEAMIH657EEC3QPJD9645546575-27BAKMJJB333339AIJHB97IFFEH77767665769-BBFBDGAD9GG3DBBGEECKHKCC7D87F83887788E73333333345456dAF1111111111-3------1--1--1111-23693455439SIJMPRG9997NNNTDDDE7DNNKGKOP-2FJ9LBB75D8CCJ3CID5E9AE3222222234AAFrOLMC93ZD3vSCBC2PUQhQNOAFCDRDcp6D8122311-1-2-1-------E737G65HD8TJLL6TNDF9BBBCHEEAADFFCIGKN--264A6------HEDD8BBEFFGEGEHEE-FFFEFFFEEGFFFEEEEEEFFHDEAA9FFEDFGFEEFGGGGDHGED9EDEE5-DEFGHGFCFHHG--376666678778DY5K333222122123122AAABB6A485EDHHNIDSQOHPMRIJKMO2222133127GFEJEFFFFLLLNOBBCBEBB7884444--x3KK78BB-------13-1-------------------------3A544454343O2 --1-A91------1A56522234434322111122222222233331454453733433555221----2--211------2222221-2426352111263256A-5-5------------------------------------------------5-----------------144F1-1-1K-144162-6132- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------2- STR:NPRED 274 STR:RPRED 61.7 SQ:SECSTR #########################################################################################################################################################################HHHHHTccHHHHTcHHHHHHHHHHHHHHHHHHGGGTccGccTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccTTcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTccccccEEEEHHHHHHHHHHTTHHHHHHTTcEEEEEEccEEEEcHHHHHHHHHHHHHHHHHccccccEEEEEEcccccEEEEEEEEccccccTTTTTGGGcTTcccccTTcccccccccHHHHHHHHHHHTTcEEEEEEETTTEEEEEEEEEccTTTTEE# DISOP:02AL 1-3,5-6,77-77,79-81,249-250,393-393,436-437,439-445| PSIPRED ccHHHHHHHcccccEEEEEcccHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccHHHEEEHHHHHHHHHHHHHHHHcccccHHHcccEEEEEEccccccccEEEEEEEEccccHHHccccEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHHcccEEEEEcccccEEEEcHHHHHHHHHHHHcccEEEcccccEEEEEEEEEccEEEEEEEEccccccHHHHHHHcccHHHcccccccccccccHHHHHHHHHHHHcccEEEEEEEccccEEEEEEEEccccccccc //