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Streptococcus pneumoniae G54 (spne4)
Gene : ciaR
DDBJ      :ciaR         CiaR response regulator TCS05
Swiss-Prot:CIAR_STRR6   RecName: Full=Transcriptional regulatory protein ciaR;

Homologs  Archaea  21/68 : Bacteria  855/915 : Eukaryota  34/199 : Viruses  0/175   --->[See Alignment]
a.4.6c.23.1
:224 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   4->221 2oqrA PDBj 1e-33 36.9 %
:RPS:PDB   1->218 3c3wB PDBj 4e-31 18.9 %
:RPS:SCOP  3->121 1p2fA2  c.23.1.1 * 1e-27 33.3 %
:RPS:SCOP  124->221 1gxpA  a.4.6.1 * 6e-21 22.4 %
:HMM:SCOP  1->178 1s8nA_ c.23.1.1 * 8.5e-35 31.1 %
:RPS:PFM   32->108 PF00072 * Response_reg 9e-12 44.2 %
:RPS:PFM   148->220 PF00486 * Trans_reg_C 4e-09 35.6 %
:HMM:PFM   4->112 PF00072 * Response_reg 4.9e-23 33.9 109/112  
:HMM:PFM   146->220 PF00486 * Trans_reg_C 4.3e-20 30.7 75/77  
:BLT:SWISS 1->224 CIAR_STRR6 e-126 100.0 %

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF56723.1 GT:GENE ciaR GT:PRODUCT CiaR response regulator TCS05 GT:DATABASE GIB00761CH01 GT:ORG spne4 GB:ACCESSION GIB00761CH01 GB:LOCATION 706799..707473 GB:FROM 706799 GB:TO 707473 GB:DIRECTION + GB:GENE ciaR GB:PRODUCT CiaR response regulator TCS05 GB:NOTE Guenzi Mol Microbiol. 1994 12(3):505-15.; identified by match to protein family HMM PF00072; match to protein family HMM PF00486 GB:PROTEIN_ID ACF56723.1 GB:DB_XREF GI:194358275 GB:GENE:GENE ciaR LENGTH 224 SQ:AASEQ MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVYFLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGYLLKDVQ GT:EXON 1|1-224:0| SW:ID CIAR_STRR6 SW:DE RecName: Full=Transcriptional regulatory protein ciaR; SW:GN Name=ciaR; OrderedLocusNames=spr0707; SW:KW Competence; Complete proteome; Cytoplasm; DNA-binding; Phosphoprotein;Transcription; Transcription regulation;Two-component regulatory system. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->224|CIAR_STRR6|e-126|100.0|224/224| GO:SWS:NREP 6 GO:SWS GO:0030420|"GO:establishment of competence for transformation"|Competence| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding| GO:SWS GO:0006350|"GO:transcription"|Transcription| GO:SWS GO:0045449|"GO:regulation of transcription"|Transcription regulation| GO:SWS GO:0000160|"GO:two-component signal transduction system (phosphorelay)"|Two-component regulatory system| BL:PDB:NREP 1 BL:PDB:REP 4->221|2oqrA|1e-33|36.9|217/226| RP:PDB:NREP 1 RP:PDB:REP 1->218|3c3wB|4e-31|18.9|206/210| RP:PFM:NREP 2 RP:PFM:REP 32->108|PF00072|9e-12|44.2|77/111|Response_reg| RP:PFM:REP 148->220|PF00486|4e-09|35.6|73/77|Trans_reg_C| HM:PFM:NREP 2 HM:PFM:REP 4->112|PF00072|4.9e-23|33.9|109/112|Response_reg| HM:PFM:REP 146->220|PF00486|4.3e-20|30.7|75/77|Trans_reg_C| GO:PFM:NREP 7 GO:PFM GO:0000156|"GO:two-component response regulator activity"|PF00072|IPR001789| GO:PFM GO:0000160|"GO:two-component signal transduction system (phosphorelay)"|PF00072|IPR001789| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF00072|IPR001789| GO:PFM GO:0000156|"GO:two-component response regulator activity"|PF00486|IPR001867| GO:PFM GO:0000160|"GO:two-component signal transduction system (phosphorelay)"|PF00486|IPR001867| GO:PFM GO:0003677|"GO:DNA binding"|PF00486|IPR001867| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF00486|IPR001867| RP:SCP:NREP 2 RP:SCP:REP 3->121|1p2fA2|1e-27|33.3|117/120|c.23.1.1| RP:SCP:REP 124->221|1gxpA|6e-21|22.4|98/103|a.4.6.1| HM:SCP:REP 1->178|1s8nA_|8.5e-35|31.1|177/190|c.23.1.1|1/1|CheY-like| OP:NHOMO 11370 OP:NHOMOORG 910 OP:PATTERN -----------------------11112-312---1--111111--14-9533--------------- 8GH7O466778455ABBAA-AI44ADAAAAA8IEFF9FGEACCF89676887ADD45711JHJ5O7GMKN7444464459JB714778HJbT-E22---57M4CDT8RAL--------------232352257382PQQPMG8EW5kQdSTSDGGDF968AB9MLEDljuK684565675555DF688342B7HUUWVWTUXHYSXXURHPDCCFVXd9BDX9FEA99A9Agc7AB9A99899AAA9979996C675CC645466677CC655675686DED8668A99888888988885555566667655A7766476786VKMkRRRWUUWTRMEdUU9EGCRKF8BBHOA5jdPDC435657696328FDAGFFC66666FDMLLEACCLEGKAA9AAAAA99D-GIJGILJKCMA2NKKNHEKMMHGFDL8C9B8CFAEFABBAAAAAAAABDC99NGA2212222222332333323323323222236CD56BEDAGSUWUaRLIIIEQQTRLJLKEJZSSKRPX23KQPNDKEDZIIKK7INJBCBDC91211111974FNTGSRFB8H86KI77D-ZSWSLURFFDAECVVEJQ9887666666323433333GP9CL66JIAGIGP9JFFMHMMJGLKNMMKOMLMMPT--25A4A------EDGGDGBFFFGFFGHFF-FHGFFFFFFHFFFFFFFFELJLDG889FFFFFFFFEFFEFEFFIEDDEEFF81CFFGGGFFFGGG--2E333335655ADUBP444333244443224DCABD7A99CGERPTROWXXIQTTTKPOR3212132126HGHPFFFFFLKNNOORGDJDEEED77671-T2998899322-22225-2-------------------------49445665456K3 ----24-------1311----1------------------------111-------1-----------------------------11----1-1-111-11-21-----------------------------------------------------1----2-1-------3-113-------2--C--11-B---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 223 STR:RPRED 99.6 SQ:SECSTR cEEEEEEcccHHHHHHHHHHHTTEEEEEEEccHHHHHHHHHHHcccEEEEccEETTEEHHHHHHHHHHHcTTcEEEEGGGcccHHHHHHHHHHTcccHHHHHHHHHHHHHHHHHHHHHGGGccHHGGHHHHHHHHHHHHHHHHccTTTTccHHHHHHHHHHTTTccEEEEcccccHHHHHHHHTccHHHHHHHHHHHHHHTTcccccHHHHHHHHHTcccccT# DISOP:02AL 122-123,125-125,224-225| PSIPRED ccEEEEEEccHHHHHHHHHHHHHccEEEEEccHHHHHHHHHHccccEEEEEcccccccHHHHHHHHHHccccccEEEEEccccHHHHHHHHccccccEEEccccHHHHHHHHHHHHHcccccccccEEEccEEEEccccEEEEccEEEcccHHHHHHHHHHHHcccccccHHHHHHHHcccccccccccHHHHHHHHHHHccccccccEEEEEccccEEEEccc //