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Streptococcus pneumoniae G54 (spne4)
Gene : fabH
DDBJ      :fabH         3-oxoacyl-(acyl-carrier-protein) synthase III
Swiss-Prot:FABH_STRZP   RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase 3;         EC=2.3.1.180;AltName: Full=3-oxoacyl-[acyl-carrier-protein] synthase III;AltName: Full=Beta-ketoacyl-ACP synthase III;         Short=KAS III;

Homologs  Archaea  2/68 : Bacteria  821/915 : Eukaryota  23/199 : Viruses  0/175   --->[See Alignment]
c.95.1
:324 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   3->306 3il5A PDBj 1e-94 57.9 %
:RPS:PDB   5->296 1b65A PDBj 3e-45 8.3 %
:RPS:SCOP  3->171 1eblA1  c.95.1.2 * 2e-59 43.2 %
:RPS:SCOP  207->298 1u0mA2  c.95.1.2 * 8e-19 21.7 %
:HMM:SCOP  1->324 1tedA_ c.95.1.2 * 7.4e-60 30.4 %
:RPS:PFM   106->183 PF08545 * ACP_syn_III 1e-22 61.5 %
:RPS:PFM   242->296 PF08541 * ACP_syn_III_C 1e-12 49.1 %
:HMM:PFM   106->183 PF08545 * ACP_syn_III 8e-33 64.1 78/80  
:HMM:PFM   234->323 PF08541 * ACP_syn_III_C 2.3e-32 46.6 88/90  
:BLT:SWISS 1->306 FABH_STRZP e-172 100.0 %
:TM
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF56437.1 GT:GENE fabH GT:PRODUCT 3-oxoacyl-(acyl-carrier-protein) synthase III GT:DATABASE GIB00761CH01 GT:ORG spne4 GB:ACCESSION GIB00761CH01 GB:LOCATION 375514..376488 GB:FROM 375514 GB:TO 376488 GB:DIRECTION + GB:GENE fabH GB:PRODUCT 3-oxoacyl-(acyl-carrier-protein) synthase III GB:NOTE identified by similarity to GB:AAK91994.1; match to protein family HMM PF08541; match to protein family HMM PF08545; match to protein family HMM TIGR00747 GB:PROTEIN_ID ACF56437.1 GB:DB_XREF GI:194357989 GB:GENE:GENE fabH LENGTH 324 SQ:AASEQ MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRHISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANKAFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDGAGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVFDFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMMEYGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI GT:EXON 1|1-324:0| SW:ID FABH_STRZP SW:DE RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase 3; EC=2.3.1.180;AltName: Full=3-oxoacyl-[acyl-carrier-protein] synthase III;AltName: Full=Beta-ketoacyl-ACP synthase III; Short=KAS III; SW:GN Name=fabH; OrderedLocusNames=SPP_0448; SW:KW Acyltransferase; Complete proteome; Cytoplasm;Fatty acid biosynthesis; Lipid synthesis; Multifunctional enzyme;Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->306|FABH_STRZP|e-172|100.0|306/324| GO:SWS:NREP 6 GO:SWS GO:0008415|"GO:acyltransferase activity"|Acyltransferase| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006633|"GO:fatty acid biosynthetic process"|Fatty acid biosynthesis| GO:SWS GO:0008610|"GO:lipid biosynthetic process"|Lipid synthesis| GO:SWS GO:0003824|"GO:catalytic activity"|Multifunctional enzyme| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| TM:NTM 2 TM:REGION 102->124| TM:REGION 303->324| SEG 307->323|llsgfgggltwgtlilt| BL:PDB:NREP 1 BL:PDB:REP 3->306|3il5A|1e-94|57.9|299/320| RP:PDB:NREP 1 RP:PDB:REP 5->296|1b65A|3e-45|8.3|276/363| RP:PFM:NREP 2 RP:PFM:REP 106->183|PF08545|1e-22|61.5|78/79|ACP_syn_III| RP:PFM:REP 242->296|PF08541|1e-12|49.1|55/90|ACP_syn_III_C| HM:PFM:NREP 2 HM:PFM:REP 106->183|PF08545|8e-33|64.1|78/80|ACP_syn_III| HM:PFM:REP 234->323|PF08541|2.3e-32|46.6|88/90|ACP_syn_III_C| GO:PFM:NREP 4 GO:PFM GO:0004315|"GO:3-oxoacyl-[acyl-carrier-protein] synthase activity"|PF08545|IPR013751| GO:PFM GO:0006633|"GO:fatty acid biosynthetic process"|PF08545|IPR013751| GO:PFM GO:0008610|"GO:lipid biosynthetic process"|PF08541|IPR013747| GO:PFM GO:0016747|"GO:transferase activity, transferring acyl groups other than amino-acyl groups"|PF08541|IPR013747| RP:SCP:NREP 2 RP:SCP:REP 3->171|1eblA1|2e-59|43.2|169/174|c.95.1.2| RP:SCP:REP 207->298|1u0mA2|8e-19|21.7|92/148|c.95.1.2| HM:SCP:REP 1->324|1tedA_|7.4e-60|30.4|313/0|c.95.1.2|1/1|Thiolase-like| OP:NHOMO 1315 OP:NHOMOORG 846 OP:PATTERN -----------------------------------1-1------------------------------ 11214---------32111-11--2-111112-11142221333112121111221131111112224631--------11-111111422114112--224333124141111111111111111111111121122211---3111111111111111112111111311111111111111121111-112333332253423222132212342111111111111132111111111111111121111-111111-1-2211111222211111111111111111111111111111111111111211111111111122333333323251223111-13--1111111111113111131122212222211111221222122222222222222222-33133112242222211121111112223122111122211111111111111111111111111--11111111211111111-211212111141121433333113155553321311111122111111211211113121231111111111111124211111112111122242222222223512111112221231111111111111111331-221221142333532333253232371-11111------12211111112111111-1111121111111111112111221111111111111111111211111111-1111211112221111222213444113111111111111111111111111111--33332425122221332111111111111122222232232113232222322221113--1111--------1-2-------------------------11----2---121 1-------1----1----------------------------------------------------------------------------------------------31----------------------------------------------------1-------------111A111115115-12-1----1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 306 STR:RPRED 94.4 SQ:SECSTR HHEEcGGGGTccccccccTTccGGGcTTcEEEEEEEEcccccTTccccEEEEEEEETTTTccccccEEEEEEEEEEccccccHHccHHHHHcEEcccEEEEEGGGHHHcHHHHHHHHHHHHTHHHHccccccccccEEEEEccTTccGGGccccHHHHHHHHHTcccccccccccGGGTcEEEEEEEEEETEEEEEEEEEEEccccGGGcccTTccHHHHccTTcHHHHHHHHHHHTccGGHccEEEEEEEcccccHHHHHHHHHTHHHHHHTTTccccTTcEEEEEEEEccccccccccTcccEE################## DISOP:02AL 1-1| PSIPRED ccccEEEEEEEEcccccccHHHHHHHHcccHHHHHHcccccEEEccccccHHHHHHHHHHHHHHHccccHHHccEEEEEccccccccccHHHHHHHHccccccEEEEEccHHHHHHHHHHHHHHHHHcccccEEEEEEEEHHHHHcccccccccEEEcccEEEEEEEccccccEEEEEEccccccccEEEcccccccccccccccccccEEEEHHHHHHHHHHHHHHHHHHHHHHccccHHHccEEEEccccHHHHHHHHHHccccHHHHHHHHHHHccccccHHHHHHHHHHHHcccccccccEEEEEEEEccccEEEEEEEc //