[GTOP] [HELP] [ORGANISMS] [SEARCH] [SUMMARY]
Streptococcus pneumoniae G54 (spne4)
Gene : gyrA
DDBJ      :gyrA         DNA gyrase, A subunit
Swiss-Prot:GYRA_STRR6   RecName: Full=DNA gyrase subunit A;         EC=5.99.1.3;

Homologs  Archaea  22/68 : Bacteria  910/915 : Eukaryota  175/199 : Viruses  8/175   --->[See Alignment]
b.68.10e.11.1
:822 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   31->484 2novC PDBj e-128 51.4 %
:BLT:PDB   506->805 1zi0B PDBj 2e-62 42.4 %
:RPS:PDB   28->484 1ab4A PDBj e-158 55.2 %
:RPS:PDB   506->602 3dwpA PDBj 1e-32 15.5 %
:RPS:PDB   615->708 3dwpC PDBj 1e-06 7.8 %
:RPS:PDB   695->804 3dwpC PDBj 4e-10 9.6 %
:RPS:SCOP  28->484 1ab4A  e.11.1.1 * e-159 55.2 %
:RPS:SCOP  506->804 1wp5A  b.68.10.1 * e-100 29.7 %
:HMM:SCOP  4->488 1bjtA_ e.11.1.1 * 2.9e-181 57.6 %
:HMM:SCOP  497->822 1wp5A_ b.68.10.1 * 3.6e-103 49.4 %
:RPS:PFM   30->440 PF00521 * DNA_topoisoIV e-160 68.6 %
:RPS:PFM   706->755 PF03989 * DNA_gyraseA_C 1e-04 34.0 %
:HMM:PFM   30->470 PF00521 * DNA_topoisoIV 7.7e-159 52.2 425/426  
:HMM:PFM   501->548 PF03989 * DNA_gyraseA_C 3.6e-11 31.2 48/50  
:HMM:PFM   551->601 PF03989 * DNA_gyraseA_C 3.6e-14 37.5 48/50  
:HMM:PFM   610->652 PF03989 * DNA_gyraseA_C 4.8e-09 25.6 43/50  
:HMM:PFM   658->703 PF03989 * DNA_gyraseA_C 2.5e-14 37.0 46/50  
:HMM:PFM   707->755 PF03989 * DNA_gyraseA_C 4.9e-11 35.4 48/50  
:HMM:PFM   758->804 PF03989 * DNA_gyraseA_C 4.7e-13 23.4 47/50  
:BLT:SWISS 1->805 GYRA_STRR6 0.0 99.6 %
:REPEAT 3|507->601|613->698|712->804
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF55945.1 GT:GENE gyrA GT:PRODUCT DNA gyrase, A subunit GT:DATABASE GIB00761CH01 GT:ORG spne4 GB:ACCESSION GIB00761CH01 GB:LOCATION complement(1088234..1090702) GB:FROM 1088234 GB:TO 1090702 GB:DIRECTION - GB:GENE gyrA GB:PRODUCT DNA gyrase, A subunit GB:NOTE identified by match to protein family HMM PF00521; match to protein family HMM PF03989; match to protein family HMM TIGR01063 GB:PROTEIN_ID ACF55945.1 GB:DB_XREF GI:194357497 GB:GENE:GENE gyrA LENGTH 822 SQ:AASEQ MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVDGHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPARFPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTGALVMGKSGIHXAYETGKGSIVLRSRTEIETTKTGRERIVVTXFPYMVNKTKVHEHIVRLVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAIQNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIRIIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIADLADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQVLSLEDEDLIEESDVLITLSNRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRLKGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTSVKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRIATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAKITEKNGLLAGLMTVQGDEDLMIITDTGVIIRTNLANISQTGRATMGVKVMRLDQDAQIVTFTTVAVAEKEEVGTENETEGEA GT:EXON 1|1-822:0| SW:ID GYRA_STRR6 SW:DE RecName: Full=DNA gyrase subunit A; EC=5.99.1.3; SW:GN Name=gyrA; OrderedLocusNames=spr1099; SW:KW ATP-binding; Complete proteome; DNA-binding; Isomerase;Nucleotide-binding; Topoisomerase. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->805|GYRA_STRR6|0.0|99.6|805/822| GO:SWS:NREP 5 GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding| GO:SWS GO:0016853|"GO:isomerase activity"|Isomerase| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0003916|"GO:DNA topoisomerase activity"|Topoisomerase| NREPEAT 1 REPEAT 3|507->601|613->698|712->804| SEG 442->456|ddllaliadladila| SEG 489->505|vlslededlieesdvli| SEG 806->821|vaekeevgtenetege| BL:PDB:NREP 2 BL:PDB:REP 31->484|2novC|e-128|51.4|451/451| BL:PDB:REP 506->805|1zi0B|2e-62|42.4|288/296| RP:PDB:NREP 4 RP:PDB:REP 28->484|1ab4A|e-158|55.2|446/477| RP:PDB:REP 506->602|3dwpA|1e-32|15.5|97/116| RP:PDB:REP 615->708|3dwpC|1e-06|7.8|94/120| RP:PDB:REP 695->804|3dwpC|4e-10|9.6|110/120| RP:PFM:NREP 2 RP:PFM:REP 30->440|PF00521|e-160|68.6|407/434|DNA_topoisoIV| RP:PFM:REP 706->755|PF03989|1e-04|34.0|50/50|DNA_gyraseA_C| HM:PFM:NREP 7 HM:PFM:REP 30->470|PF00521|7.7e-159|52.2|425/426|DNA_topoisoIV| HM:PFM:REP 501->548|PF03989|3.6e-11|31.2|48/50|DNA_gyraseA_C| HM:PFM:REP 551->601|PF03989|3.6e-14|37.5|48/50|DNA_gyraseA_C| HM:PFM:REP 610->652|PF03989|4.8e-09|25.6|43/50|DNA_gyraseA_C| HM:PFM:REP 658->703|PF03989|2.5e-14|37.0|46/50|DNA_gyraseA_C| HM:PFM:REP 707->755|PF03989|4.9e-11|35.4|48/50|DNA_gyraseA_C| HM:PFM:REP 758->804|PF03989|4.7e-13|23.4|47/50|DNA_gyraseA_C| GO:PFM:NREP 10 GO:PFM GO:0003677|"GO:DNA binding"|PF00521|IPR002205| GO:PFM GO:0003918|"GO:DNA topoisomerase (ATP-hydrolyzing) activity"|PF00521|IPR002205| GO:PFM GO:0005524|"GO:ATP binding"|PF00521|IPR002205| GO:PFM GO:0005694|"GO:chromosome"|PF00521|IPR002205| GO:PFM GO:0006265|"GO:DNA topological change"|PF00521|IPR002205| GO:PFM GO:0003677|"GO:DNA binding"|PF03989|IPR006691| GO:PFM GO:0003916|"GO:DNA topoisomerase activity"|PF03989|IPR006691| GO:PFM GO:0005524|"GO:ATP binding"|PF03989|IPR006691| GO:PFM GO:0005694|"GO:chromosome"|PF03989|IPR006691| GO:PFM GO:0006265|"GO:DNA topological change"|PF03989|IPR006691| RP:SCP:NREP 2 RP:SCP:REP 28->484|1ab4A|e-159|55.2|446/477|e.11.1.1| RP:SCP:REP 506->804|1wp5A|e-100|29.7|293/323|b.68.10.1| HM:SCP:REP 4->488|1bjtA_|2.9e-181|57.6|458/760|e.11.1.1|1/1|Type II DNA topoisomerase| HM:SCP:REP 497->822|1wp5A_|3.6e-103|49.4|320/0|b.68.10.1|1/1|GyrA/ParC C-terminal domain-like| OP:NHOMO 1924 OP:NHOMOORG 1115 OP:PATTERN -----------------------111111111-----------1111111111--------111---- 1111211111111111112-12111211111122221111211122222222222222222222221222222222221111111111222212222112222222222222222222222222211111111111111111111122222222222222222222222222222222222221111111112222222222222222222222222222212222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222212122222222222221222222222111221122111121111111111112222222222222222222222222222222222-22223222222222222222222222222222222222222222222222222221111111111112222222222222111112222222222222222222222222222222232222222222222222222222221121222222222111222112121111111111111111111111122111111111111111111111111111222223222222222222222222222222221-2222211111122222222222222222-22222222222222222222222222222222222222222222222222221222222222222112222222222222222222222222112222222122222222222222222222222222222222222222222222222322222222222222222212222222222222221211112-22222222222222222231111111111122 221122114121112111111111111111111111111121111111111111111111111-1111-1111-1111111-111111-1--11111111-211111-22-221322111-11112-215A1-3151--11-11211--1---1-212-13912111111-43113222F2233232111233422221 ---1---------------1---------------111-1----------------------------------------------------------------------------------------------------------------------------------1-1-- STR:NPRED 805 STR:RPRED 97.9 SQ:SECSTR HHHHcccccccccccTHHHHHHHHHHHcTTTcccTTTcccHHHHHHHHHHHHTTcccccccEEHHHHHHHHHHHTccccHHHHHHHHHHTTcTTTcccccEEEEcccccTTccccccTTTcEEEEcTTHHHHcTTTTTTcccEEEcTTcccEEEccccccccHHHHHcEEEccccccEEEccccHHHHHHHHHHHHHcTTccHHHHTTTccccccccccEEcccHHHHHHHHHcEEEEEEEcEEEEEcHEEETcEEEEEEccTTccHHHHHHHHHHHHTTTcccccccEEEccccccccEEEccHHHHHHHHHHHHHHHHcTTEEEEEEEcEEEETTEEEEccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHcccHHHHHHHHHHcEEccHHHHHHHHTccGGGGcHHHHHHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHccccccEEHHHHHHHHHHHccGGGcccEEEEccGGGHHHccGcccccHHHHTTTcTTcEEEEEcccccGGGGGGcHHHHHHHcEEEEEETTTTGGGTcHHHHHHHHHHHHHHHHHcHEEEEEEEEcccccHHHHHHTcccTTccccTTcccccccHEHHHHHHHHHHHHHHHHHHHHHHTccGGccHHHHHHHHHTHHGGGEEEccccEEEEEEEEEEccTTcccccEEEEEEEEEEEEEEETTEEEEEEEEEETTccEEEEEEETTccccGGGHHHHHHHHHHHHHHHccEEEETTccccHHHHHHccccEEEEcccccccccccccc################# DISOP:02AL 1-4,8-8,527-529,780-781,783-783,810-823| PSIPRED ccccccEEccHHHHHHHHHHHHHHHHHHHHcccHHHHcccHHHHHHHHHHHHcccccccccEEEHHHHHHHHHHcccccHHHHHHHHHHHHHHHHcccEEEEcccccccccccccHHHHHHHHHHHHHHHHHHHHccccccccEEcccccccccEEEcccccEEEEEccccEEEccccccccccHHHHHHHHHHHHHcccccHHHHHHHccccccccccEEEcHHHccHHHHccccEEEEEEEEEEEEEcccccEEEEEcccccccHHHHHHHHHHHHHccccccHHHHHHHccccccEEEEEEcccccHHHHHHHHHHHccEEEEEEEEEEEEEccEEEEccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHccccHHHHHHHccccccHHcHHHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHcccccccEEEcccccccHHcccccccEEEEEcccccEEEEEHHHccccccccccccccccccccEEEEEEEEEcccEEEEEEccccEEEEEHHHccccccccccEEEHHHcccccccEEEEEEEcccccccccEEEEEEcccEEEEEEHHHHcccccccEEEEEcccccEEEEEEEcccccEEEEEEcccEEEEEEHHHccccccccccEEEEEEccccEEEEEEEEccccEEEEEEccccEEEEEHHHccccccccccEEcccccccccEEEEEEEcccccEEEEEEcccEEEEEEHHHccccccccccEEEEEEccccEEEEEEEEcccccccccccccccccc //