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Streptococcus pneumoniae G54 (spne4)
Gene : metB
DDBJ      :metB         cystathionine gamma-synthase (CGS) (O-succinylhomoserine(thiol)-lyase)
Swiss-Prot:             

Homologs  Archaea  47/68 : Bacteria  754/915 : Eukaryota  190/199 : Viruses  0/175   --->[See Alignment]
c.67.1
:364 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   7->358 1ibjA PDBj 9e-66 38.7 %
:RPS:PDB   5->361 3e6gA PDBj 2e-97 40.2 %
:RPS:SCOP  6->363 1cs1A  c.67.1.3 * 7e-61 40.2 %
:HMM:SCOP  5->363 1cs1A_ c.67.1.3 * 2.9e-96 38.4 %
:RPS:PFM   8->362 PF01053 * Cys_Met_Meta_PP 3e-76 46.6 %
:HMM:PFM   9->363 PF01053 * Cys_Met_Meta_PP 2e-118 51.8 355/386  
:BLT:SWISS 1->361 METB_HAEIN 6e-92 47.4 %
:PROS 189->203|PS00868|CYS_MET_METAB_PP
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF56676.1 GT:GENE metB GT:PRODUCT cystathionine gamma-synthase (CGS) (O-succinylhomoserine(thiol)-lyase) GT:DATABASE GIB00761CH01 GT:ORG spne4 GB:ACCESSION GIB00761CH01 GB:LOCATION complement(1399962..1401056) GB:FROM 1399962 GB:TO 1401056 GB:DIRECTION - GB:GENE metB GB:PRODUCT cystathionine gamma-synthase (CGS) (O-succinylhomoserine(thiol)-lyase) GB:NOTE identified by match to protein family HMM PF01053 GB:PROTEIN_ID ACF56676.1 GB:DB_XREF GI:194358228 GB:GENE:GENE metB LENGTH 364 SQ:AASEQ MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRSTGFDYTRTKNPTRSKAEEVLATIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLYGGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAKLAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELYEKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLYTGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIGIEDARDLIADLRQALEG GT:EXON 1|1-364:0| BL:SWS:NREP 1 BL:SWS:REP 1->361|METB_HAEIN|6e-92|47.4|361/369| PROS 189->203|PS00868|CYS_MET_METAB_PP|PDOC00677| SEG 157->171|klaklahakgakvvv| BL:PDB:NREP 1 BL:PDB:REP 7->358|1ibjA|9e-66|38.7|351/380| RP:PDB:NREP 1 RP:PDB:REP 5->361|3e6gA|2e-97|40.2|346/368| RP:PFM:NREP 1 RP:PFM:REP 8->362|PF01053|3e-76|46.6|354/384|Cys_Met_Meta_PP| HM:PFM:NREP 1 HM:PFM:REP 9->363|PF01053|2e-118|51.8|355/386|Cys_Met_Meta_PP| GO:PFM:NREP 2 GO:PFM GO:0006520|"GO:cellular amino acid metabolic process"|PF01053|IPR000277| GO:PFM GO:0030170|"GO:pyridoxal phosphate binding"|PF01053|IPR000277| RP:SCP:NREP 1 RP:SCP:REP 6->363|1cs1A|7e-61|40.2|358/384|c.67.1.3| HM:SCP:REP 5->363|1cs1A_|2.9e-96|38.4|359/0|c.67.1.3|1/1|PLP-dependent transferases| OP:NHOMO 3003 OP:NHOMOORG 991 OP:PATTERN 22-1-11111111111-111111-3332233321--------1451-1-1221-111-1--2221--- 1741421233222144433-34223533333244443567133365423442446565--324-433334346664441-131-----33222211---11435442344---------------2323322431144444---43---2--1--11332321----2-1-22222232223234322--12435555555555555556633435553453511333333752333333333333323334422-11113-1-331112-1-253323-------222122221211111111111112111222333222-241573333333231227721113241-5333-22--1-242333321316-33334-----35867543B567544444443446156755836783-555666665866443543434544345222222224222335811-----------------------11112346424643463344754444333844441453465441143333455635664323111343222222222244221123-2-241----565354423445442113231122212112111111123121113332314434335455444444544355442--3321------52332332222222222-2222222232222222223333334462222222222222222422222222-32233333333322-311111111112214333333-22212223333332312231333344251656424221--------12223222222332233232333331111113122--11--------1----------------------------11--22222-22 ----113-631-5645554667556655544344646444444444445538965544444455544425534545534555554433-57454483222323433-3624151121111111122111372-2131121111211111111111111111135241112233323235n4442365685643342225 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 364 STR:RPRED 100.0 SQ:SECSTR ccccccHHHHHHHTTccccTTTcccccccccccccccccccHHHHHHccccccHHHHHHHHHHHHHHTccEEEEEccHHHHHHHHHTTccTTcEEEEEccccHHHHHHHHHHHHHHHEEEEcTTcHHHHHHHccTTEEEEEEEcccTTTcccccHHHHHHHHHHTTcEEEEEcccccTTTccGGGGTccEEEEETTTTTTcccccccEEEEEcccHHHHHHHHHHHHHcccccHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHTcTTEEEEEcTTcccEEEEEETHHHHHHHHHHHccccEEcccccccccEEEcTTTTTTcccccTTTTTccccccEEEEEcccccHHHHHHHHTTcTHH DISOP:02AL 1-4| PSIPRED ccccccccEEEEEcccccccccccccccHHccEEEEcccccccccccccccccccHHHHHHHHHHHHcccEEEEEcccHHHHHHHHHHcccccEEEEEccccHHHHHHHHHHHHcccEEEEEcccHHHHHHHccccccEEEEEcccccccccccHHHHHHHHHHcccEEEEEccccccccccHHHHcccEEEEccccccccccccccEEEEEcHHHHHHHHHHHHHHHcccccHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHccHHHHHHcccccccEEEEEEccHHHHHHHHHHccEEEEEcccccccEEEEcccHHHHHcccHHHHHHccccccEEEEEEEcccHHHHHHHHHHHHcc //