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Streptococcus pneumoniae G54 (spne4)
Gene : metG
DDBJ      :metG         methionyl-tRNA synthetase
Swiss-Prot:SYM_STRR6    RecName: Full=Methionyl-tRNA synthetase;         EC=6.1.1.10;AltName: Full=Methionine--tRNA ligase;         Short=MetRS;

Homologs  Archaea  68/68 : Bacteria  909/915 : Eukaryota  194/199 : Viruses  1/175   --->[See Alignment]
a.27.1b.40.4c.26.1
:665 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   4->474 2ct8A PDBj e-113 50.4 %
:BLT:PDB   558->662 1pybA PDBj 4e-21 53.9 %
:RPS:PDB   3->519 2d54A PDBj 4e-75 37.0 %
:RPS:PDB   559->664 1e7zA PDBj 4e-28 26.9 %
:RPS:SCOP  3->360 1a8hA2  c.26.1.1 * 1e-57 41.9 %
:RPS:SCOP  363->591 1rqgA1  a.27.1.1 * 1e-29 22.8 %
:HMM:SCOP  2->360 2d5bA2 c.26.1.1 * 2.1e-104 38.6 %
:HMM:SCOP  362->576 1rqgA1 a.27.1.1 * 2.8e-45 33.3 %
:HMM:SCOP  557->664 1gd7A_ b.40.4.4 * 5.6e-31 43.4 %
:RPS:PFM   8->372 PF09334 * tRNA-synt_1g e-107 54.0 %
:RPS:PFM   409->486 PF08264 * Anticodon_1 3e-05 36.2 %
:RPS:PFM   516->592 PF06353 * DUF1062 6e-04 31.2 %
:RPS:PFM   570->651 PF01588 * tRNA_bind 1e-11 48.1 %
:HMM:PFM   6->373 PF09334 * tRNA-synt_1g 1.9e-129 44.7 365/391  
:HMM:PFM   568->662 PF01588 * tRNA_bind 1.3e-24 45.7 92/95  
:HMM:PFM   401->533 PF08264 * Anticodon_1 2.7e-08 20.5 117/152  
:BLT:SWISS 1->665 SYM_STRR6 0.0 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF55528.1 GT:GENE metG GT:PRODUCT methionyl-tRNA synthetase GT:DATABASE GIB00761CH01 GT:ORG spne4 GB:ACCESSION GIB00761CH01 GB:LOCATION 696667..698664 GB:FROM 696667 GB:TO 698664 GB:DIRECTION + GB:GENE metG GB:PRODUCT methionyl-tRNA synthetase GB:NOTE identified by match to protein family HMM PF01588; match to protein family HMM PF09334; match to protein family HMM TIGR00398; match to protein family HMM TIGR00399 GB:PROTEIN_ID ACF55528.1 GB:DB_XREF GI:194357080 GB:GENE:GENE metG LENGTH 665 SQ:AASEQ MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDVFYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHEKVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGHEVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRTTFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILRFHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRYYLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVTEFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEALRDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVTVVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKVEIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVANLKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG GT:EXON 1|1-665:0| SW:ID SYM_STRR6 SW:DE RecName: Full=Methionyl-tRNA synthetase; EC=6.1.1.10;AltName: Full=Methionine--tRNA ligase; Short=MetRS; SW:GN Name=metG; Synonyms=metS; OrderedLocusNames=spr0696; SW:KW Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm;Ligase; Nucleotide-binding; Protein biosynthesis; RNA-binding;tRNA-binding. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->665|SYM_STRR6|0.0|100.0|665/665| GO:SWS:NREP 8 GO:SWS GO:0004812|"GO:aminoacyl-tRNA ligase activity"|Aminoacyl-tRNA synthetase| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016874|"GO:ligase activity"|Ligase| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0006412|"GO:translation"|Protein biosynthesis| GO:SWS GO:0003723|"GO:RNA binding"|RNA-binding| GO:SWS GO:0000049|"GO:tRNA binding"|tRNA-binding| SEG 487->500|lgleevsslenlsl| BL:PDB:NREP 2 BL:PDB:REP 4->474|2ct8A|e-113|50.4|415/465| BL:PDB:REP 558->662|1pybA|4e-21|53.9|102/107| RP:PDB:NREP 2 RP:PDB:REP 3->519|2d54A|4e-75|37.0|494/500| RP:PDB:REP 559->664|1e7zA|4e-28|26.9|104/173| RP:PFM:NREP 4 RP:PFM:REP 8->372|PF09334|e-107|54.0|354/363|tRNA-synt_1g| RP:PFM:REP 409->486|PF08264|3e-05|36.2|69/153|Anticodon_1| RP:PFM:REP 516->592|PF06353|6e-04|31.2|77/144|DUF1062| RP:PFM:REP 570->651|PF01588|1e-11|48.1|81/100|tRNA_bind| HM:PFM:NREP 3 HM:PFM:REP 6->373|PF09334|1.9e-129|44.7|365/391|tRNA-synt_1g| HM:PFM:REP 568->662|PF01588|1.3e-24|45.7|92/95|tRNA_bind| HM:PFM:REP 401->533|PF08264|2.7e-08|20.5|117/152|Anticodon_1| GO:PFM:NREP 13 GO:PFM GO:0000166|"GO:nucleotide binding"|PF09334|IPR015413| GO:PFM GO:0004812|"GO:aminoacyl-tRNA ligase activity"|PF09334|IPR015413| GO:PFM GO:0005524|"GO:ATP binding"|PF09334|IPR015413| GO:PFM GO:0005737|"GO:cytoplasm"|PF09334|IPR015413| GO:PFM GO:0006412|"GO:translation"|PF09334|IPR015413| GO:PFM GO:0006418|"GO:tRNA aminoacylation for protein translation"|PF09334|IPR015413| GO:PFM GO:0000166|"GO:nucleotide binding"|PF08264|IPR013155| GO:PFM GO:0004812|"GO:aminoacyl-tRNA ligase activity"|PF08264|IPR013155| GO:PFM GO:0005524|"GO:ATP binding"|PF08264|IPR013155| GO:PFM GO:0005737|"GO:cytoplasm"|PF08264|IPR013155| GO:PFM GO:0006412|"GO:translation"|PF08264|IPR013155| GO:PFM GO:0006418|"GO:tRNA aminoacylation for protein translation"|PF08264|IPR013155| GO:PFM GO:0000049|"GO:tRNA binding"|PF01588|IPR002547| RP:SCP:NREP 2 RP:SCP:REP 3->360|1a8hA2|1e-57|41.9|344/348|c.26.1.1| RP:SCP:REP 363->591|1rqgA1|1e-29|22.8|206/210|a.27.1.1| HM:SCP:REP 2->360|2d5bA2|2.1e-104|38.6|345/0|c.26.1.1|1/1|Nucleotidylyl transferase| HM:SCP:REP 362->576|1rqgA1|2.8e-45|33.3|207/210|a.27.1.1|1/1|Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases| HM:SCP:REP 557->664|1gd7A_|5.6e-31|43.4|106/109|b.40.4.4|1/1|Nucleic acid-binding proteins| OP:NHOMO 1886 OP:NHOMOORG 1172 OP:PATTERN 22222222222222222223222212211112111111111112222211111231223222223112 1121211111111111111-11111111111111111111111112111112111111112111111111111111111122132111111112222-12111211212111111111111111122221121221122111111121112122211111112211111111112111112111211111112222222221222222232223322422232241222112233333333333333333333322311322222222113331123333333333322333433433333333323333333343333333311311222111212112111222111231121111111131111111121111222211111112111111111111111111111111111111111121112212211122112111111111111111111111111111111111122221111111111111111121112111111111111111111111111111111111111111111111111111111211111111111222111111111111111111111111111112112211111222222211111111111111112111111111111111111111111111111-1112111111111111111222122122-2212222222221111111111111111111111111111111121111121111111111111111111111111112111111111111111111111111111111111113111111111111111-111111111311111121221111111111111111111111112112222211121111-11122211113211212221111221222221 2211223-41122231233322223232234344443333333323222222222223133323322223222232222222233313-23122222222232322134253222321121121222223H2-223221121221-21222111211222244332-325B43223332X2333333363223354233 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- STR:NPRED 665 STR:RPRED 100.0 SQ:SECSTR ccccEEEEEEEEEETTccccHHHHHHHHHHHHHHHHHHHTTcEEEEEEEEEcccHHHHHHHHHTTccHHHHHHHHHHHHHHHHHHTTccccEEEETTcHHHHHHHHHHHHHHHHTTcEEEEEEEEEEETTTTEEEcTTTccTTccTTEccccTccTTTccccEEEEEEEEEEcGGGGHHHHHHHHHHcTTccccHHHHHHHHHTTcccccEEcEEETTTcccccEETTEEEEEEcHHHHHHTHHHHTTTTTTcHHTHHHHHHGGGEEEEEEGGGHHHHHTHHHHHHHHHTcccccEEEEEccEEcTTccccGGGTccccHHHHHHHHcHHHHHHHHHHHccTTccEEccHHHHHHHHHHHcccccHHHHHHHHHHHHHHcTTcccccccccccccHHHGGGGGGGHHHHHHHHHTTcHHHHHHHHHHHHHHHHHHHHHHcHHHHTTHHHcHHHHHHHHHHHHHHHHHHHHHHTTTcHHHHHHHHHHTTccccccGGGGGcccccccccccccccccccccccccEEEEEEETTETccGEEEEEEEcccccHHHHHHHHTTccccHHHHHcccccEEEEETTccTEEEEEcEccccccEEEEEccTTTccHHTHHTTcEEEEEcccccEETETTEEEccEEcEEEccccEEEccccTTccTTcccG DISOP:02AL 1-1,529-549,663-666| PSIPRED cccccEEEEcccccccccccHHHHHHHHHHHHHHHHHHHcccEEEccccccHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHccccccccEEcccHHHHHHHHHHHHHHHHcccEEEccEEEEccccccccccHHHHHHHcccccccccccccccccccEEEEcccEEEEcHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHcccccccccccccEEEEEEEcccccEEEEccccccccHHHccccccccccccccccccEEEEEEEEHHHHHHHHHHHHHHHcccccccEEEEEEEEEEccccccccccccccHHHHHHHcccHHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccccccHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHccHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccccccccccccccccccccccccHHHHHHHHHHHHHHHHccccccccccHHHHHHHHHHHcccccHHHHHHHHHHHHHHccccccEEEEEEEEEccccccEEEEEEHHHcccHHHHcccEEEEEEccccHHHHcccEEEEEEEEEcccccEEEEccccccccccccc //