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Streptococcus pneumoniae G54 (spne4)
Gene : nanB
DDBJ      :nanB         neuraminidase B
Swiss-Prot:NANB_STRPN   RecName: Full=Sialidase B;         EC=3.2.1.18;AltName: Full=Neuraminidase B;Flags: Precursor;

Homologs  Archaea  0/68 : Bacteria  30/915 : Eukaryota  0/199 : Viruses  0/175   --->[See Alignment]
b.29.1b.68.1d.258.1
:697 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   37->697 2jkbA PDBj 0.0 99.2 %
:RPS:PDB   71->223 3bodA PDBj 1e-04 12.6 %
:RPS:PDB   226->594 3b7fA PDBj 1e-08 13.9 %
:RPS:SCOP  68->220 1sliA1  b.29.1.9 * 4e-22 35.3 %
:RPS:SCOP  211->301 1dilA  b.68.1.1 * 1e-04 28.9 %
:RPS:SCOP  384->441 1um0A  d.258.1.1 * 6e-04 18.9 %
:RPS:SCOP  458->672 1eurA  b.68.1.1 * 2e-26 21.4 %
:HMM:SCOP  67->223 2sliA1 b.29.1.9 * 7e-29 25.3 %
:HMM:SCOP  228->689 1ms9A2 b.68.1.1 * 1e-50 26.7 %
:RPS:PFM   68->220 PF02973 * Sialidase 2e-26 47.3 %
:RPS:PFM   486->638 PF10339 * Vel1p 3e-04 31.3 %
:HMM:PFM   42->227 PF02973 * Sialidase 4.1e-68 48.6 179/190  
:HMM:PFM   281->290 PF02012 * BNR 3.7e-05 80.0 10/12  
:HMM:PFM   518->528 PF02012 * BNR 0.00038 45.5 11/12  
:BLT:SWISS 1->697 NANB_STRPN 0.0 99.3 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF54964.1 GT:GENE nanB GT:PRODUCT neuraminidase B GT:DATABASE GIB00761CH01 GT:ORG spne4 GB:ACCESSION GIB00761CH01 GB:LOCATION complement(1537369..1539462) GB:FROM 1537369 GB:TO 1539462 GB:DIRECTION - GB:GENE nanB GB:PRODUCT neuraminidase B GB:NOTE identified by match to protein family HMM PF02012; match to protein family HMM PF02973 GB:PROTEIN_ID ACF54964.1 GB:DB_XREF GI:194356516 GB:GENE:GENE nanB LENGTH 697 SQ:AASEQ MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQGGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYFSIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMYVNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQEVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVYDETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYMTSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLSNVXQYIDLEINDLTK GT:EXON 1|1-697:0| SW:ID NANB_STRPN SW:DE RecName: Full=Sialidase B; EC=3.2.1.18;AltName: Full=Neuraminidase B;Flags: Precursor; SW:GN Name=nanB; OrderedLocusNames=SP_1687; SW:KW 3D-structure; Complete proteome; Glycosidase; Hydrolase; Repeat;Signal. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->697|NANB_STRPN|0.0|99.3|697/697| GO:SWS:NREP 3 GO:SWS GO:0016798|"GO:hydrolase activity, acting on glycosyl bonds"|Glycosidase| GO:SWS GO:0008152|"GO:metabolic process"|Glycosidase| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| SEG 50->66|lnnksidissllldkls| BL:PDB:NREP 1 BL:PDB:REP 37->697|2jkbA|0.0|99.2|661/661| RP:PDB:NREP 2 RP:PDB:REP 71->223|3bodA|1e-04|12.6|135/178| RP:PDB:REP 226->594|3b7fA|1e-08|13.9|337/358| RP:PFM:NREP 2 RP:PFM:REP 68->220|PF02973|2e-26|47.3|148/183|Sialidase| RP:PFM:REP 486->638|PF10339|3e-04|31.3|131/198|Vel1p| HM:PFM:NREP 3 HM:PFM:REP 42->227|PF02973|4.1e-68|48.6|179/190|Sialidase| HM:PFM:REP 281->290|PF02012|3.7e-05|80.0|10/12|BNR| HM:PFM:REP 518->528|PF02012|0.00038|45.5|11/12|BNR| GO:PFM:NREP 2 GO:PFM GO:0004308|"GO:exo-alpha-sialidase activity"|PF02973|IPR004124| GO:PFM GO:0005975|"GO:carbohydrate metabolic process"|PF02973|IPR004124| RP:SCP:NREP 4 RP:SCP:REP 68->220|1sliA1|4e-22|35.3|153/196|b.29.1.9| RP:SCP:REP 211->301|1dilA|1e-04|28.9|90/381|b.68.1.1| RP:SCP:REP 384->441|1um0A|6e-04|18.9|53/365|d.258.1.1| RP:SCP:REP 458->672|1eurA|2e-26|21.4|206/361|b.68.1.1| HM:SCP:REP 67->223|2sliA1|7e-29|25.3|154/0|b.29.1.9|1/1|Concanavalin A-like lectins/glucanases| HM:SCP:REP 228->689|1ms9A2|1e-50|26.7|344/0|b.68.1.1|1/1|Sialidases| OP:NHOMO 48 OP:NHOMOORG 30 OP:PATTERN -------------------------------------------------------------------- ------1--------------------------------------------------------2-----------1------------1111-1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111-111---22233223232-------------------------------------------22------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 661 STR:RPRED 94.8 SQ:SECSTR ####################################ccccccEEEEEEEEEcccEEcHHHHGGGcccccEEEEEEEEcccccEEEEEEEEEEEEccccccEEEEEEETTTEEEEEEEcccccEEEEcccccccccccEEEEEEEEEEEEEEEETTEEEEEETTcccEEEcccccccccccccEEEEEEcccTTcccccccccEEEEEEEETTEEHHHHHHTTcTcETTEEEEEEEcTTcccccEEEEEEEcTTcEEEEEEEccccTTcEEEEccccEEEEEEccTTcccEEccccccccccccccccEEEEEEEccTTcTTcEEEEETEEEEEccTTcccEEcHHHTTccGGHTcTHHHHHcccccccEEEEEEcTTcTTcEEEEETcEEEEccccccEEEcccccTcEEccTTcccEEccTTcccTTcccccccccccEEEEEEccccTTEEEEEETTEEEEETTTTEEEcGGGGcTTTEcccEEEEEEccccTTcEEEEEcccccccccccccEEEEccTTcccEEEccTcccccccccTccEEcccccccEEEEcTTccEEEEEEccTTcccEEETcTEcccccEEEEEEEEEEEEEEETTEEEEEEEEEccccccccEEEEEEEEcTTTccEEEEEEEEcccTTcccccEEEEEcTTccEEEEEEccccccTTcccccccEEEEEEcHHHHcc DISOP:02AL 1-4,697-698| PSIPRED ccccccHHHHccHHHHHHHHcccccEEEccccccccEEEEEEEccccEEEcccEEEccccHHHHHccccEEEEEEEEcccccccEEEEEEccccccccccEEEEEEEcccEEEEEEEccccccEEEEcccHHHHEEccccccccEEEEEEcccccEEEEEEccEEEEEEccccccEEccccccEEEEEccEEccccEEEEcccEEEEEEEccccccHHHccccccccccEEEEcccccccccEEEEEEEEEcccccEEEEEEccccccccccccccEEEEEEEccccccccEEEEEcccccccccccccccccccccccccccEEEccEEEEEccccEEEEEEEEEccccccccccccccccccccccEEEEEEEEccccEEEEEEcccEEccccccccEEEEEccccEEEEcccccEEcccEEEEccccEEEEccccEEccEEEEEccccccccccEEEEEEEccccccccccEEccccccccccEEEEEccccEEEEEccEEEEEEEEcccEEEEEEcccccEEEEccccccccccccccEEEEEcccEEEEEEEcccccEEEEEEccccccccccEEcccccccccccEEEEEEccccccccEEEEEEcccccccccccEEEEEEEEcccccEEccccccEEccccccccEEEEEccccEEEEEEEcccccEEEEEEEEEEEEEEEEEEHHHcc //