[GTOP] [HELP] [ORGANISMS] [SEARCH] [SUMMARY]
Streptococcus pneumoniae G54 (spne4)
Gene : polA
DDBJ      :polA         DNA polymerase I
Swiss-Prot:DPO1_STRPN   RecName: Full=DNA polymerase I;         Short=POL I;         EC=2.7.7.7;

Homologs  Archaea  0/68 : Bacteria  907/915 : Eukaryota  96/199 : Viruses  20/175   --->[See Alignment]
a.60.7c.120.1c.55.3e.8.1
:877 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   4->259 1ut5B PDBj 4e-13 28.8 %
:BLT:PDB   300->877 1u4bA PDBj e-153 50.1 %
:RPS:PDB   3->877 1bgxT PDBj 0.0 39.8 %
:RPS:SCOP  3->174 1a76A2  c.120.1.2 * 3e-36 20.1 %
:RPS:SCOP  178->278 1exnA1  a.60.7.1 * 3e-26 27.7 %
:RPS:SCOP  301->467 1l3sA1  c.55.3.5 * 4e-14 31.1 %
:RPS:SCOP  466->877 1bgxT4  e.8.1.1 * e-143 47.8 %
:HMM:SCOP  3->175 1bgxT2 c.120.1.2 * 1e-55 51.5 %
:HMM:SCOP  175->279 1xo1A1 a.60.7.1 * 4e-37 52.4 %
:HMM:SCOP  300->467 2hhvA1 c.55.3.5 * 6.1e-34 31.0 %
:HMM:SCOP  468->877 2hhvA2 e.8.1.1 * 3.3e-150 59.0 %
:RPS:PFM   5->154 PF02739 * 5_3_exonuc_N 1e-41 57.5 %
:RPS:PFM   176->271 PF01367 * 5_3_exonuc 8e-27 60.4 %
:RPS:PFM   511->873 PF00476 * DNA_pol_A e-122 63.4 %
:HMM:PFM   495->876 PF00476 * DNA_pol_A 2.7e-152 52.0 379/383  
:HMM:PFM   4->174 PF02739 * 5_3_exonuc_N 3e-66 53.3 169/169  
:HMM:PFM   176->274 PF01367 * 5_3_exonuc 1.3e-36 58.6 99/101  
:BLT:SWISS 1->877 DPO1_STRPN 0.0 99.5 %
:PROS 703->722|PS00447|DNA_POLYMERASE_A

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF55506.1 GT:GENE polA GT:PRODUCT DNA polymerase I GT:DATABASE GIB00761CH01 GT:ORG spne4 GB:ACCESSION GIB00761CH01 GB:LOCATION 30478..33111 GB:FROM 30478 GB:TO 33111 GB:DIRECTION + GB:GENE polA GB:PRODUCT DNA polymerase I GB:NOTE identified by match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF02739; match to protein family HMM TIGR00593 GB:PROTEIN_ID ACF55506.1 GB:DB_XREF GI:194357058 GB:GENE:GENE polA LENGTH 877 SQ:AASEQ MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQLMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEYGSLEGIYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK GT:EXON 1|1-877:0| SW:ID DPO1_STRPN SW:DE RecName: Full=DNA polymerase I; Short=POL I; EC=2.7.7.7; SW:GN Name=polA; OrderedLocusNames=SP_0032; SW:KW Complete proteome; DNA damage; DNA repair; DNA replication;DNA-binding; DNA-directed DNA polymerase; Exonuclease; Hydrolase;Nuclease; Nucleotidyltransferase; Transferase. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->877|DPO1_STRPN|0.0|99.5|877/877| GO:SWS:NREP 10 GO:SWS GO:0006974|"GO:response to DNA damage stimulus"|DNA damage| GO:SWS GO:0006281|"GO:DNA repair"|DNA repair| GO:SWS GO:0006260|"GO:DNA replication"|DNA replication| GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding| GO:SWS GO:0003887|"GO:DNA-directed DNA polymerase activity"|DNA-directed DNA polymerase| GO:SWS GO:0004527|"GO:exonuclease activity"|Exonuclease| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| GO:SWS GO:0004518|"GO:nuclease activity"|Nuclease| GO:SWS GO:0016779|"GO:nucleotidyltransferase activity"|Nucleotidyltransferase| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 703->722|PS00447|DNA_POLYMERASE_A|PDOC00412| BL:PDB:NREP 2 BL:PDB:REP 4->259|1ut5B|4e-13|28.8|236/272| BL:PDB:REP 300->877|1u4bA|e-153|50.1|575/580| RP:PDB:NREP 1 RP:PDB:REP 3->877|1bgxT|0.0|39.8|814/828| RP:PFM:NREP 3 RP:PFM:REP 5->154|PF02739|1e-41|57.5|146/165|5_3_exonuc_N| RP:PFM:REP 176->271|PF01367|8e-27|60.4|96/100|5_3_exonuc| RP:PFM:REP 511->873|PF00476|e-122|63.4|355/360|DNA_pol_A| HM:PFM:NREP 3 HM:PFM:REP 495->876|PF00476|2.7e-152|52.0|379/383|DNA_pol_A| HM:PFM:REP 4->174|PF02739|3e-66|53.3|169/169|5_3_exonuc_N| HM:PFM:REP 176->274|PF01367|1.3e-36|58.6|99/101|5_3_exonuc| GO:PFM:NREP 7 GO:PFM GO:0003677|"GO:DNA binding"|PF02739|IPR020046| GO:PFM GO:0008409|"GO:5'-3' exonuclease activity"|PF02739|IPR020046| GO:PFM GO:0003677|"GO:DNA binding"|PF01367|IPR020047| GO:PFM GO:0008409|"GO:5'-3' exonuclease activity"|PF01367|IPR020047| GO:PFM GO:0003677|"GO:DNA binding"|PF00476|IPR001098| GO:PFM GO:0003887|"GO:DNA-directed DNA polymerase activity"|PF00476|IPR001098| GO:PFM GO:0006260|"GO:DNA replication"|PF00476|IPR001098| RP:SCP:NREP 4 RP:SCP:REP 3->174|1a76A2|3e-36|20.1|164/207|c.120.1.2| RP:SCP:REP 178->278|1exnA1|3e-26|27.7|101/105|a.60.7.1| RP:SCP:REP 301->467|1l3sA1|4e-14|31.1|167/172|c.55.3.5| RP:SCP:REP 466->877|1bgxT4|e-143|47.8|402/406|e.8.1.1| HM:SCP:REP 3->175|1bgxT2|1e-55|51.5|163/173|c.120.1.2|1/1|PIN domain-like| HM:SCP:REP 175->279|1xo1A1|4e-37|52.4|105/0|a.60.7.1|1/1|5' to 3' exonuclease, C-terminal subdomain| HM:SCP:REP 300->467|2hhvA1|6.1e-34|31.0|168/0|c.55.3.5|1/1|Ribonuclease H-like| HM:SCP:REP 468->877|2hhvA2|3.3e-150|59.0|407/0|e.8.1.1|1/1|DNA/RNA polymerases| OP:NHOMO 1513 OP:NHOMOORG 1023 OP:PATTERN -------------------------------------------------------------------- 1221211111111122222-22112222222222222222212222121111222111112231222333111111111111222222111111111--1111111111111111111111111111111111111111111111112111111111111111111111111111111111112111111112222222322222222222222222321132142222222222222222222222222222111111111111111121111111111111111111111111111111111111111111111111111111112111111111111111111112112212122212111111111111111111111111111111111111111111111111-111131111111111111111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111211-1121111111111121111112112211111111111111111111111111111211111222111232122122111111111111111111111111111112221122112222222222222222222221-1111211111122222222221222222-22222222222222222222222222222222222222322222222222221233323323222111111111111111112111111111111111111111111111111111111111111111111111111222222222222222222222222111111111111111111111111111112-11211111111211111111111111111111 33--431-B54---1---------------------------------------------------------------------------------------------42511222-2122222572526G2-4251212222211221222-72131212112212111311212244K4445364A7-552332111 ------11------------------------------1---------------11-------1-1-11--------------------11-----1-------1---------1------1----------------1----------1-1--------2-------1------ STR:NPRED 875 STR:RPRED 99.8 SQ:SECSTR ##cTTcccccccTHHHHTTcccTTTTccccccccccccccTTHHHHHHHGGGTHccccccccccccccccccGGGGTTTcccccccTTcTTGGGTHHHHHHHTTccccccccccHHHHHHHHHHHHHHHTcccccccccTTccTTccTTccccccccccccccEcccTTHHHHTcccGGGTTTTTTccccccccccccccccccTTTTTGGGTTcccccccccccccTTTTcHHHHcccccTTcGGGcccccccccccccccccccccccHHHHHHHHTTTTcccTTcccccccccccEEEccccccEEEcccccTTcccEEEcccccTTTccccEEEcccccEEEccccEHHHHHHcccccHHHHHccccTTHHHHHHHHHHTcccccccccHHHHHHHHcTGGcccHHHHHHTTTcccTTHHHHHHcccccccHHHHHHHHHHHHHHHHHHHTTcHHHHHHHHHTTcHHHHHTTHHHHHHHHHHHHHHcccccTTTHHHHHHHHHHHHHHHHHHHHHccccccccccHHHHTTTTTTccccccccccccccccGGGTcTTTTGGGTccTTHHHHTHHHHccccTTccccTTTcccTTcccccEEEcccccccccEEEcccTTccccccTTTTTTGGGcccccccccEEEEEEccHHHHHHHHTTTcTTHHHHHHHTccHHHHHHHHHHTccGTTcccTTHHHHHHHHHHHTTccccHHHHHHHccccHHHHHHHHHHHHHHcHHHHHHHHHHTHHHHTTcccccccccccccGGGccccHHHHHHHHHHHTTHHHHTHHHHHHHTHHHHHHHHHHHHHHTcEEEEEETTEEEEEccHHTHHHHHHHHHHHHHccccccccccEEccEEccHHHHc DISOP:02AL 1-2,292-294,296-296,877-878| PSIPRED cccccEEEEEccHHHHHHHHHHHHcccccccccccccHHHHHHHHHHHHHHHcccccEEEEEEEcccccHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHcccEEEEccccHHHHHHHHHHHHHHccccEEEEcccHHHHHHccccEEEEEccccccEEEEccHHHHHHHccccHHHHHHHHHHcccccccccccccccHHHHHHHHHHcccHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHcccccccccHHHcccccccHHHHHHHHHHHcHHHHHHHHcccccccccccccccccHHHHHHHHccccccccccccccccccEEEEEEEcccEEEEEccccccccHHHHHHHccccEEEEcHHHHHHHHHHcccccccHHHHHHHHHHHHcccccccHHHHHHHHcccccccHHHHcccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHcccEEcHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccHHHHHHHHHHccccccccccccccccccHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccEEEcccccccEEEEccccHHHccccccHHHHHHEEEEEccccEEEEEEEccHHHHHHHHHHHccHHHHHHHHccccHHHHHHHHHcccccHHHccHHHHHHHHHHHHHHHHcccHHHHHHHccccHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHcccEEccccccccccccccccHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccEEEEEEEccEEEEEccHHHHHHHHHHHHHHHHccccccccEEEEccccccHHHHc //