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Streptococcus pneumoniae G54 (spne4)
Gene : ptsI
DDBJ      :ptsI         phosphoenolpyruvate-protein phosphotransferase
Swiss-Prot:PT1_STREI    RecName: Full=Phosphoenolpyruvate-protein phosphotransferase;         EC=2.7.3.9;AltName: Full=Phosphotransferase system, enzyme I;

Homologs  Archaea  64/68 : Bacteria  823/915 : Eukaryota  38/199 : Viruses  0/175   --->[See Alignment]
a.60.10c.1.12c.8.1
:577 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   2->574 2wqdA PDBj 0.0 59.6 %
:RPS:PDB   1->534 1dikA PDBj e-117 22.3 %
:RPS:SCOP  25->145 1ezaA1  a.60.10.1 * 2e-32 33.3 %
:RPS:SCOP  141->235 1zymA2  c.8.1.2 * 4e-20 47.4 %
:RPS:SCOP  250->534 1dikA1  c.1.12.2 * 1e-77 29.8 %
:HMM:SCOP  23->146 1zymA1 a.60.10.1 * 7.6e-34 45.5 %
:HMM:SCOP  127->251 1zymA2 c.8.1.2 * 7.1e-37 43.2 %
:HMM:SCOP  250->554 1h6zA1 c.1.12.2 * 6.5e-112 46.4 %
:RPS:PFM   5->129 PF05524 * PEP-utilisers_N 3e-21 50.4 %
:RPS:PFM   152->227 PF00391 * PEP-utilizers 3e-14 51.4 %
:RPS:PFM   258->534 PF02896 * PEP-utilizers_C 3e-78 53.6 %
:HMM:PFM   252->545 PF02896 * PEP-utilizers_C 3.7e-129 57.9 292/294  
:HMM:PFM   5->129 PF05524 * PEP-utilisers_N 1e-35 40.7 123/123  
:HMM:PFM   154->227 PF00391 * PEP-utilizers 5.8e-25 46.6 73/81  
:HMM:PFM   217->259 PF01782 * RimM 0.00093 18.6 43/84  
:BLT:SWISS 1->577 PT1_STREI 0.0 90.8 %
:PROS 186->197|PS00370|PEP_ENZYMES_PHOS_SITE
:PROS 451->469|PS00742|PEP_ENZYMES_2
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACF56151.1 GT:GENE ptsI GT:PRODUCT phosphoenolpyruvate-protein phosphotransferase GT:DATABASE GIB00761CH01 GT:ORG spne4 GB:ACCESSION GIB00761CH01 GB:LOCATION complement(1052183..1053916) GB:FROM 1052183 GB:TO 1053916 GB:DIRECTION - GB:GENE ptsI GB:PRODUCT phosphoenolpyruvate-protein phosphotransferase GB:NOTE identified by match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417 GB:PROTEIN_ID ACF56151.1 GB:DB_XREF GI:194357703 GB:GENE:GENE ptsI LENGTH 577 SQ:AASEQ MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARLDAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAEAGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIVIAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGDILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAANIGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVRTMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRIMFPMVALLKEFRAAKAVFNEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEVDFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHSEGKWAGMCGEMAGDQTAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEVLELQKEYVNFD GT:EXON 1|1-577:0| SW:ID PT1_STREI SW:DE RecName: Full=Phosphoenolpyruvate-protein phosphotransferase; EC=2.7.3.9;AltName: Full=Phosphotransferase system, enzyme I; SW:GN Name=ptsI; SW:KW Cytoplasm; Kinase; Magnesium; Metal-binding;Phosphotransferase system; Sugar transport; Transferase; Transport. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->577|PT1_STREI|0.0|90.8|577/577| GO:SWS:NREP 7 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016301|"GO:kinase activity"|Kinase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0009401|"GO:phosphoenolpyruvate-dependent sugar phosphotransferase system"|Phosphotransferase system| GO:SWS GO:0008643|"GO:carbohydrate transport"|Sugar transport| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| GO:SWS GO:0006810|"GO:transport"|Transport| PROS 186->197|PS00370|PEP_ENZYMES_PHOS_SITE|PDOC00527| PROS 451->469|PS00742|PEP_ENZYMES_2|PDOC00527| SEG 236->249|eqaaefkaageaya| BL:PDB:NREP 1 BL:PDB:REP 2->574|2wqdA|0.0|59.6|569/570| RP:PDB:NREP 1 RP:PDB:REP 1->534|1dikA|e-117|22.3|521/869| RP:PFM:NREP 3 RP:PFM:REP 5->129|PF05524|3e-21|50.4|123/123|PEP-utilisers_N| RP:PFM:REP 152->227|PF00391|3e-14|51.4|74/79|PEP-utilizers| RP:PFM:REP 258->534|PF02896|3e-78|53.6|274/300|PEP-utilizers_C| HM:PFM:NREP 4 HM:PFM:REP 252->545|PF02896|3.7e-129|57.9|292/294|PEP-utilizers_C| HM:PFM:REP 5->129|PF05524|1e-35|40.7|123/123|PEP-utilisers_N| HM:PFM:REP 154->227|PF00391|5.8e-25|46.6|73/81|PEP-utilizers| HM:PFM:REP 217->259|PF01782|0.00093|18.6|43/84|RimM| GO:PFM:NREP 8 GO:PFM GO:0005351|"GO:sugar:hydrogen symporter activity"|PF05524|IPR008731| GO:PFM GO:0005737|"GO:cytoplasm"|PF05524|IPR008731| GO:PFM GO:0008965|"GO:phosphoenolpyruvate-protein phosphotransferase activity"|PF05524|IPR008731| GO:PFM GO:0009401|"GO:phosphoenolpyruvate-dependent sugar phosphotransferase system"|PF05524|IPR008731| GO:PFM GO:0016310|"GO:phosphorylation"|PF00391|IPR008279| GO:PFM GO:0016772|"GO:transferase activity, transferring phosphorus-containing groups"|PF00391|IPR008279| GO:PFM GO:0016310|"GO:phosphorylation"|PF02896|IPR000121| GO:PFM GO:0016772|"GO:transferase activity, transferring phosphorus-containing groups"|PF02896|IPR000121| RP:SCP:NREP 3 RP:SCP:REP 25->145|1ezaA1|2e-32|33.3|120/123|a.60.10.1| RP:SCP:REP 141->235|1zymA2|4e-20|47.4|95/124|c.8.1.2| RP:SCP:REP 250->534|1dikA1|1e-77|29.8|282/365|c.1.12.2| HM:SCP:REP 23->146|1zymA1|7.6e-34|45.5|123/0|a.60.10.1|1/1|Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain| HM:SCP:REP 127->251|1zymA2|7.1e-37|43.2|125/0|c.8.1.2|1/1|Phosphohistidine domain| HM:SCP:REP 250->554|1h6zA1|6.5e-112|46.4|302/366|c.1.12.2|1/1|Phosphoenolpyruvate/pyruvate domain| OP:NHOMO 1930 OP:NHOMOORG 925 OP:PATTERN 11111-11111111112112211121113-21112111111112211212332111111111111--1 -1124111111-1--------2--13------222213221-11121222212331-1--2-2211221221---111211221111111111111--------11--2111111111111111122222212222344331112141322221111------11113332------------23111213211111111111111111111111111111111122222233211111111111111222222111221211122222321111111122221112111111111111111111111111112111111112221122222222222-222322232222232221-13-121122222221113344412222224432222222211111111113-22322232242-1222233332222222222233332221111111143314344--111---1111111111111111111111242212222233333333333443433333433323321244422332333323223222262222222232222213621233232333123324444522322222-----------111111111-1112223362212232333333343332333333331-2322311-11163333336667677766-5666666646566666665344333344433434433424334465455543-4444444444441111111112222-23321111111111111113333323111314444454533333333311111111113335333333433333333333332222--1311111111111111311----1-1-11111111111111---1111121111332 --------2111-------11-1---1----------------------111-A---11--------------------------------------------------2-----------------------------------------------------2---------111221U221--2142-21123113- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 577 STR:RPRED 100.0 SQ:SECSTR cccccccTTcEEEEEEEEcTTTccEEEEEEEEEcccccEETTTHHHHcHHHHHHHHHHHHHHEEEEETTEEEEEEcccccccHHHHHHHHHHHHHTTcccHHHHHHHccGGGGGTTTccccccHHHHHTccccEEEEEEEEEccHHHHHTTccTTccEEEEEccccGGGHHHHHHHHccEEEEccccTTcHHHHHHHHHTcEEEEccTTcEEETTTTEEEccccETTEEEcccEEEEETTcEEEcccccccccccHHHHHHHHHHHHHcccEEEEEcccHHHHHHHHHTTcccEEEEEcTHHHHcHHHHHHHHHHHHHHHHHHHHHTTccEEEEcccccGGGTccccHTTccccTTccccTHHHHHHcHHHHHHHHHHHHHHHHHHHHHcEEEEcccccHHHHHHHHHHHHHHHHHHHccccccccccEEEEEEccHHHHHTHHHHHHHccEEEEEHHHHHHHHHTccHHHHTTcccccTTTTTHHHHHHHHHHHHHHHTcEEEEEcTTTTcHHHHHHHHHHTccEEEEcTTTHHHHHHHHHTccHHHHHHHHHHHHTccHHHHHHHHHHHcHHTHH DISOP:02AL 1-1,60-67| PSIPRED ccEEEEEEEEcccEEEEEEEEEEcccccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHccHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHccccccHHHHcccccEEEEccccHHHHHHccHHHHHHHEEcccccccHHHHHHHHHcccEEEcccHHHHHcccccEEEEEccccEEEEcccHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccEEEEEEccccHHHHHHHHHcccccccHHHHHHHHccccccccHHHHHHHHHHHHHHHccccEEEEEcccccccccccccccccccccccccEEEHHHccccHHHHHHHHHHHHHHHHHcccEEEEEccccHHHHHHHHHHHHHHHHHHHHcccccccccEEEEEEccHHHHHHHHHHHHHccEEEEcccHHHHHHHHHccccHHHHHHcccccHHHHHHHHHHHHHHHHcccEEEEEccccccHHHHHHHHHccccEEEEcHHHHHHHHHHHHHHcHHHHHHHHHHHHHccccHHHHHHHHHHHHccc //